Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55846853 . C A CCDS32450.1:NM_001025195.1:c.1048Gga>Tga_NP_001020366.1:p.350G>* Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:331 A:1349 0.0 0.0 E -137.1 167.5 0.0 0.0 0.0 HOH
 2.874
 O
 O
GLY B:331 B:2349 0.0 0.0 E -140.6 164.4 0.0 0.0 0.0 HOH
 2.804
 O
 O
GLY C:331 C:3349 0.0 0.0 E -139.1 166.7 0.0 0.0 0.0 HOH
 3.101
 O
 O
GLY D:331 D:4349 0.0 0.0 E -137.1 170.6 0.0 0.0 0.0 HOH
 2.979
 O
 O
GLY E:331 E:5349 0.0 0.0 E -139.1 166.2 0.0 0.0 0.0 HOH
 2.934
 O
 O
GLY F:331 F:6349 0.0 0.0 E -137.6 164.2 0.0 0.0 0.0 HOH
 3.164
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:331 A:1349 0.0 0.0 E -141.3 168.9 0.0 0.0 0.0 HOH
 2.869
 O
 O
GLY B:331 B:2349 0.0 0.0 E -137.6 164.2 0.0 0.0 0.0 HOH
 2.818
 O
 O
GLY C:331 C:3349 0.0 0.0 E -151.3 157.1 0.0 0.0 0.0 HOH
 2.808
 O
 O
GLY D:331 D:4349 0.0 0.0 E -134.3 166.9 NA NA NA
GLY E:331 E:5349 0.0 0.0 E -142.2 163.6 NA NA NA
GLY F:331 F:6349 0.0 0.0 E -138.7 168.9 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:331 A:1349 0.0 0.0 E -154.5 162.9 0.0 0.0 0.0 HOH
 4.440
 O
 O
GLY B:331 B:2349 0.0 0.0 E -142.4 159.9 0.0 0.0 0.0 HOH
 3.841
 O
 O
GLY C:331 C:3349 0.0 0.0 E -133.1 171.0 0.0 0.0 0.0 HOH
 2.930
 O
 O
GLY D:331 D:4349 0.0 0.0 E -127.4 162.2 0.0 0.0 0.0 HOH
 3.349
 C
 O
GLY E:331 E:5349 0.0 0.0 E -142.0 162.2 0.0 0.0 0.0 HOH
 2.793
 O
 O
GLY F:331 F:6349 0.0 0.0 E -150.4 173.2 0.0 0.0 0.0 HOH
 6.825
 O
 O
GLY G:331 G:1349 0.0 0.0 E -144.0 154.1 NA NA NA
GLY H:331 H:2349 0.0 0.0 E -149.3 157.4 NA NA NA
GLY I:331 I:3349 0.0 0.0 E -132.2 170.1 NA NA NA
GLY J:331 J:4349 0.0 0.0 E -159.6 147.3 NA NA NA
GLY K:331 K:5349 0.0 0.0 E -132.8 179.0 NA NA NA
GLY L:331 L:6349 0.0 0.0 E -135.8 166.7 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:331 A:1349 0.0 0.0 E -135.6 170.2 0.0 0.0 0.0 HOH
 3.170
 O
 O
GLY B:331 B:2349 0.0 0.0 E -137.1 169.1 0.0 0.0 0.0 HOH
 2.722
 O
 O
GLY C:331 C:3349 0.0 0.0 E -136.6 169.4 0.0 0.0 0.0 HOH
 2.825
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:331 A:1349 0.0 0.0 E -136.1 172.1 0.0 0.0 0.0 HOH
 2.887
 O
 O
GLY B:331 B:2349 0.0 0.0 E -135.0 161.9 0.0 0.0 0.0 HOH
 2.638
 O
 O
GLY C:331 C:3349 0.0 0.0 E -128.9 160.7 0.0 0.0 0.0 HOH
 2.879
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:331 A:1349 0.0 0.0 E -130.1 168.2 0.0 0.0 0.0 TCH
HOH
 9.900
3.559
 O
O
 O3
O
GLY B:331 B:2349 0.0 0.0 E -132.3 168.7 0.0 0.0 0.0 TCH
HOH
 8.286
3.717
 O
O
 O3
O
GLY C:331 C:3349 1.0 0.013 E -130.5 167.4 1.0 0.013 0.0 HOH
 2.667
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:331 A:1349 0.0 0.0 E -140.6 164.7 0.0 0.0 0.0 HOH
 3.067
 O
 O
GLY B:331 B:2349 0.0 0.0 E -140.4 164.4 0.0 0.0 0.0 HOH
 2.898
 O
 O
GLY C:331 C:3349 0.0 0.0 E -135.2 164.6 0.0 0.0 0.0 HOH
 2.888
 O
 O
GLY D:331 D:4349 0.0 0.0 E -140.2 165.3 0.0 0.0 0.0 HOH
 3.014
 O
 O
GLY E:331 E:5349 0.0 0.0 E -139.5 165.0 0.0 0.0 0.0 HOH
 2.938
 O
 O
GLY F:331 F:6349 0.0 0.0 E -135.9 167.7 0.0 0.0 0.0 HOH
 2.967
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:329 A:349 0.0 0.0 E -133.7 170.6 0.0 0.0 0.0 HOH
 3.040
 O
 O
GLY B:329 B:349 0.0 0.0 E -145.7 166.5 0.0 0.0 0.0 HOH
 2.992
 O
 O
GLY C:329 C:349 0.0 0.0 E -132.7 169.3 0.0 0.0 0.0 HOH
 2.829
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:329 A:349 0.0 0.0 E -144.8 161.0 0.0 0.0 0.0 HOH
 3.021
 O
 O
GLY B:329 B:349 0.0 0.0 E -153.4 158.4 0.0 0.0 0.0 HOH
 2.714
 O
 O
GLY C:329 C:349 0.0 0.0 E -160.1 162.6 0.0 0.0 0.0 HOH
 2.864
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:329 A:349 0.0 0.0 E -142.0 170.5 0.0 0.0 0.0 HOH
 2.862
 O
 O
GLY B:329 B:349 0.0 0.0 E -140.6 166.9 0.0 0.0 0.0 HOH
 3.311
 O
 O
GLY C:329 C:349 0.0 0.0 E -140.2 168.3 0.0 0.0 0.0 HOH
 2.701
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:329 A:349 0.0 0.0 E -134.0 161.0 0.0 0.0 0.0 HOH
 3.661
 O
 O
GLY B:329 B:349 0.0 0.0 E -140.2 166.4 0.0 0.0 0.0 HOH
 2.825
 O
 O
GLY C:329 C:349 0.0 0.0 E -146.8 154.9 0.0 0.0 0.0 HOH
 2.631
 O
 O
GLY D:329 D:349 0.0 0.0 E -136.4 -177.2 NA NA NA
GLY E:329 E:349 0.0 0.0 E -143.8 161.1 NA NA NA
GLY F:329 F:349 0.0 0.0 E -148.1 161.8 NA NA NA
GLY G:329 G:349 0.0 0.0 E -152.7 170.4 NA NA NA
GLY H:329 H:349 0.0 0.0 E -143.0 155.5 NA NA NA
GLY I:329 I:349 0.0 0.0 E -140.8 163.8 NA NA NA
GLY J:329 J:349 0.0 0.0 E -142.6 160.0 NA NA NA
GLY K:329 K:349 0.0 0.0 E -123.4 168.8 NA NA NA
GLY L:329 L:349 0.0 0.0 E -143.4 160.2 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:329 A:1349 0.0 0.0 E -139.9 167.7 0.0 0.0 0.0 HOH
 2.866
 O
 O
GLY B:329 B:2349 0.0 0.0 E -135.4 166.3 0.0 0.0 0.0 HOH
 2.974
 O
 O
GLY C:329 C:3349 0.0 0.0 E -141.7 167.9 0.0 0.0 0.0 HOH
 3.026
 O
 O
GLY D:329 D:4349 0.0 0.0 E -146.4 170.0 NA NA NA
GLY E:329 E:5349 0.0 0.0 E -140.0 168.9 NA NA NA
GLY F:329 F:6349 0.0 0.0 E -139.5 164.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:329 A:1349 0.0 0.0 E -149.6 163.6 0.0 0.0 0.0 HOH
 3.109
 O
 O
GLY B:329 B:2349 0.0 0.0 E -137.3 163.7 0.0 0.0 0.0 HOH
 3.039
 O
 O
GLY C:329 C:3349 0.0 0.0 E -137.4 164.9 0.0 0.0 0.0 HOH
 3.032
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:329 A:349 0.0 0.0 E -136.0 164.1 0.0 0.0 0.0 HOH
 2.798
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:329 A:349 0.0 0.0 E -142.0 165.5 0.0 0.0 0.0 HOH
 2.874
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:329 A:349 0.0 0.0 E -144.2 165.7 0.0 0.0 0.0 HOH
 2.841
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:328 A:349 0.0 0.0 E -139.2 169.0 0.0 0.0 0.0 HOH
 2.955
 O
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:326 A:1349 0.0 0.0 E -139.2 163.0 0.0 0.0 0.0 HOH
 2.587
 O
 O
GLY B:326 B:2349 0.0 0.0 E -140.1 163.7 0.0 0.0 0.0 HOH
 7.888
 C
 O
GLY C:326 C:3349 0.0 0.0 E -140.4 163.4 0.0 0.0 0.0 HOH
 8.639
 C
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:326 A:348 0.0 0.0 E -136.7 163.1 0.0 0.0 0.0 HOH
 3.434
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:349 A:349 0.0 0.0 E -139.7 167.2