Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55846859 . T A CCDS32450.1:NM_001025195.1:c.1042Atg>Ttg_NP_001020366.1:p.348M>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 MET A:329 A:1347 0.0 0.0 E -110.6 115.6 0.0 0.0 0.0 HOH
 6.383
 O
 O
MET B:329 B:2347 0.0 0.0 E -104.5 125.1 0.0 0.0 0.0 HOH
 6.424
 O
 O
MET C:329 C:3347 0.0 0.0 E -109.7 123.0 0.0 0.0 0.0 HOH
 6.619
 O
 O
MET D:329 D:4347 0.0 0.0 E -107.0 130.6 0.0 0.0 0.0 HOH
 6.664
 O
 O
MET E:329 E:5347 0.0 0.0 E -103.3 123.1 0.0 0.0 0.0 HOH
 6.463
 O
 O
MET F:329 F:6347 0.0 0.0 E -110.6 125.4 0.0 0.0 0.0 HOH
 6.707
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 MET A:329 A:1347 0.0 0.0 E -111.3 123.1 0.0 0.0 0.0 HOH
 6.539
 O
 O
MET B:329 B:2347 0.0 0.0 E -115.3 115.5 0.0 0.0 0.0 HOH
 6.431
 O
 O
MET C:329 C:3347 0.0 0.0 E -115.5 114.9 0.0 0.0 0.0 HOH
 6.314
 O
 O
MET D:329 D:4347 0.0 0.0 E -101.6 120.7 NA NA NA
MET E:329 E:5347 0.0 0.0 E -108.7 118.5 NA NA NA
MET F:329 F:6347 0.0 0.0 E -108.6 122.5 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 MET A:329 A:1347 0.0 0.0 E -108.5 104.5 0.0 0.0 0.0 HOH
 8.662
 O
 O
MET B:329 B:2347 0.0 0.0 E -101.7 127.0 0.0 0.0 0.0 HOH
 7.282
 CG
 O
MET C:329 C:3347 0.0 0.0 E -109.9 119.9 0.0 0.0 0.0 HOH
 6.387
 O
 O
MET D:329 D:4347 0.0 0.0 E -112.1 117.6 0.0 0.0 0.0 HOH
 7.079
 CG
 O
MET E:329 E:5347 0.0 0.0 E -110.6 127.6 0.0 0.0 0.0 HOH
 6.612
 O
 O
MET F:329 F:6347 0.0 0.0 E -116.3 115.0 0.0 0.0 0.0
MET G:329 G:1347 0.0 0.0 E -106.9 129.5 NA NA NA
MET H:329 H:2347 0.0 0.0 E -118.8 122.9 NA NA NA
MET I:329 I:3347 0.0 0.0 E -99.4 128.4 NA NA NA
MET J:329 J:4347 0.0 0.0 E -112.5 115.5 NA NA NA
MET K:329 K:5347 0.0 0.0 E -100.8 128.4 NA NA NA
MET L:329 L:6347 0.0 0.0 E -112.7 109.0 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:329 A:1347 0.0 0.0 E -116.2 113.4 0.0 0.0 0.0 HOH
 7.028
 O
 O
MET B:329 B:2347 0.0 0.0 E -115.3 114.2 0.0 0.0 0.0 HOH
 6.507
 O
 O
MET C:329 C:3347 0.0 0.0 E -117.4 113.5 0.0 0.0 0.0 HOH
 6.635
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:329 A:1347 0.0 0.0 E -113.6 118.2 0.0 0.0 0.0 HOH
 6.682
 O
 O
MET B:329 B:2347 0.0 0.0 E -106.8 117.7 0.0 0.0 0.0 HOH
 6.537
 O
 O
MET C:329 C:3347 0.0 0.0 E -119.9 115.6 0.0 0.0 0.0 HOH
 6.509
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:329 A:1347 0.0 0.0 E -107.1 122.3 0.0 0.0 0.0 HOH
 8.308
 O
 O
MET B:329 B:2347 0.0 0.0 E -107.8 121.5 0.0 0.0 0.0 HOH
 8.342
 O
 O
MET C:329 C:3347 0.0 0.0 E -107.3 121.6 0.0 0.0 0.0 HOH
 6.143
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:329 A:1347 0.0 0.0 E -105.5 126.0 0.0 0.0 0.0 HOH
 6.609
 O
 O
MET B:329 B:2347 0.0 0.0 E -106.0 120.7 0.0 0.0 0.0 HOH
 6.587
 O
 O
MET C:329 C:3347 0.0 0.0 E -104.6 121.4 0.0 0.0 0.0 HOH
 6.473
 O
 O
MET D:329 D:4347 0.0 0.0 E -106.2 124.9 0.0 0.0 0.0 HOH
 6.518
 O
 O
MET E:329 E:5347 0.0 0.0 E -102.4 124.3 0.0 0.0 0.0 HOH
 6.405
 O
 O
MET F:329 F:6347 0.0 0.0 E -105.1 121.4 0.0 0.0 0.0 HOH
 6.663
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:327 A:347 0.0 0.0 E -97.7 120.8 0.0 0.0 0.0 HOH
 6.511
 O
 O
MET B:327 B:347 0.0 0.0 E -102.7 120.1 0.0 0.0 0.0 HOH
 6.844
 O
 O
MET C:327 C:347 0.0 0.0 E -104.2 117.2 0.0 0.0 0.0 HOH
 6.723
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:327 A:347 0.0 0.0 E -112.7 120.6 0.0 0.0 0.0 HOH
 6.751
 O
 O
MET B:327 B:347 0.0 0.0 E -104.7 124.4 0.0 0.0 0.0 HOH
 6.548
 O
 O
MET C:327 C:347 0.0 0.0 E -103.8 126.8 0.0 0.0 0.0 HOH
 6.645
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:327 A:347 0.0 0.0 E -113.2 125.2 0.0 0.0 0.0 HOH
 6.680
 O
 O
MET B:327 B:347 0.0 0.0 E -113.3 124.4 0.0 0.0 0.0 HOH
 6.320
 O
 O
MET C:327 C:347 0.0 0.0 E -113.3 124.1 0.0 0.0 0.0 HOH
 6.727
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:327 A:347 0.0 0.0 E -124.0 110.6 0.0 0.0 0.0 HOH
 6.890
 O
 O
MET B:327 B:347 0.0 0.0 E -95.2 122.2 0.0 0.0 0.0 HOH
 6.767
 O
 O
MET C:327 C:347 0.0 0.0 E -126.9 98.0 0.0 0.0 0.0 HOH
 6.519
 O
 O
MET D:327 D:347 0.0 0.0 E -122.1 115.4 NA NA NA
MET E:327 E:347 0.0 0.0 E -98.7 125.2 NA NA NA
MET F:327 F:347 0.0 0.0 E -115.2 113.3 NA NA NA
MET G:327 G:347 0.0 0.0 E -123.2 89.1 NA NA NA
MET H:327 H:347 0.0 0.0 E -128.1 107.7 NA NA NA
MET I:327 I:347 0.0 0.0 E -109.7 135.3 NA NA NA
MET J:327 J:347 0.0 0.0 E -126.2 107.1 NA NA NA
MET K:327 K:347 0.0 0.0 E -119.7 102.9 NA NA NA
MET L:327 L:347 0.0 0.0 E -92.9 115.9 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 MET A:327 A:1347 0.0 0.0 E -111.3 121.1 0.0 0.0 0.0 HOH
 6.779
 O
 O
MET B:327 B:2347 0.0 0.0 E -117.1 119.3 0.0 0.0 0.0 HOH
 6.627
 O
 O
MET C:327 C:3347 0.0 0.0 E -104.1 123.2 0.0 0.0 0.0 HOH
 6.588
 O
 O
MET D:327 D:4347 0.0 0.0 E -115.4 117.5 NA NA NA
MET E:327 E:5347 0.0 0.0 E -104.8 121.8 NA NA NA
MET F:327 F:6347 0.0 0.0 E -106.6 123.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 MET A:327 A:1347 0.0 0.0 E -111.1 120.7 0.0 0.0 0.0 HOH
 6.557
 O
 O
MET B:327 B:2347 0.0 0.0 E -112.4 116.1 0.0 0.0 0.0 HOH
 6.718
 O
 O
MET C:327 C:3347 0.0 0.0 E -104.5 124.8 0.0 0.0 0.0 HOH
 6.735
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 MET A:327 A:347 0.0 0.0 E -105.3 118.6 0.0 0.0 0.0 HOH
 6.560
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 MET A:327 A:347 0.0 0.0 E -105.4 127.5 0.0 0.0 0.0 HOH
 6.689
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 MET A:327 A:347 0.0 0.0 E -105.0 121.8 0.0 0.0 0.0 HOH
 6.588
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 MET A:326 A:347 0.0 0.0 E -102.3 124.6 0.0 0.0 0.0 HOH
 6.767
 O
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 MET A:324 A:1347 0.0 0.0 E -98.3 126.3 0.0 0.0 0.0 HOH
 6.698
 O
 O
MET B:324 B:2347 0.0 0.0 E -84.0 133.1 0.0 0.0 0.0 HOH
 7.403
 CA
 O
MET C:324 C:3347 0.0 0.0 E -100.7 135.4 0.0 0.0 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 MET A:324 A:346 0.0 0.0 E -107.0 111.7 0.0 0.0 0.0 HOH
 6.733
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 MET A:347 A:347 0.0 0.0 E -101.4 128.3