Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55846878 . A C CCDS32450.1:NM_001025195.1:c.1023aaT>aaG_NP_001020366.1:p.341N>K Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ASN A:322 A:1340 84.0 0.525 -107.7 77.5 84.0 0.525 0.0 HOH
 2.495
 O
 O
ASN B:322 B:2340 165.0 1.0 -140.6 56.8 165.0 1.0 0.0 HOH
 2.668
 ND2
 O
ASN C:322 C:3340 84.0 0.525 -99.6 93.0 84.0 0.525 0.0 HOH
 2.796
 ND2
 O
ASN D:322 D:4340 73.0 0.456 -76.8 -48.5 73.0 0.456 0.0 HOH
 2.469
 ND2
 O
ASN E:322 E:5340 90.0 0.562 -105.5 91.7 90.0 0.562 0.0 HOH
 2.736
 O
 O
ASN F:322 F:6340 155.0 0.969 T -169.6 -10.2 155.0 0.969 0.0 HOH
 2.774
 CB
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASN A:322 A:1340 151.0 0.944 -117.7 45.9 151.0 0.944 0.0 HOH
 2.910
 ND2
 O
ASN B:322 B:2340 75.0 0.469 -121.2 93.5 75.0 0.469 0.0 HOH
 3.534
 ND2
 O
ASN C:322 C:3340 87.0 0.544 -97.1 93.9 87.0 0.544 0.0 HOH
 2.446
 O
 O
ASN D:322 D:4340 145.0 0.906 S -126.3 20.5 NA NA NA
ASN E:322 E:5340 108.0 0.675 -103.0 63.7 NA NA NA
ASN F:322 F:6340 89.0 0.556 -125.4 101.6 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASN A:322 A:1340 67.0 0.419 -91.5 53.8 67.0 0.419 0.0 HOH
 3.107
 ND2
 O
ASN B:322 B:2340 153.0 0.956 -59.1 88.8 153.0 0.956 0.0 HOH
 2.460
 OD1
 O
ASN C:322 C:3340 98.0 0.613 -115.5 157.6 98.0 0.613 0.0 HOH
 3.800
 O
 O
ASN D:322 D:4340 60.0 0.375 -95.4 -176.8 60.0 0.375 0.0 HOH
 4.973
 O
 O
ASN E:322 E:5340 54.0 0.338 -58.8 161.7 54.0 0.338 0.0 HOH
 4.103
 OD1
 O
ASN F:322 F:6340 102.0 0.637 -97.7 90.6 102.0 0.637 0.0 HOH
 4.840
 O
 O
ASN G:322 G:1340 107.0 0.669 -143.4 63.4 NA NA NA
ASN H:322 H:2340 88.0 0.55 -93.0 -21.0 NA NA NA
ASN I:322 I:3340 76.0 0.475 -80.3 64.8 NA NA NA
ASN J:322 J:4340 83.0 0.519 -121.7 -45.0 NA NA NA
ASN K:322 K:5340 156.0 0.975 T -173.0 8.5 NA NA NA
ASN L:322 L:6340 95.0 0.594 -111.7 61.6 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:322 A:1340 138.0 0.863 -116.3 67.9 138.0 0.863 0.0 HOH
 4.918
 C
 O
ASN B:322 B:2340 139.0 0.869 -115.6 67.4 139.0 0.869 0.0 HOH
 5.333
 C
 O
ASN C:322 C:3340 141.0 0.881 -115.4 66.9 141.0 0.881 0.0 HOH
 2.377
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:322 A:1340 120.0 0.75 -122.5 84.0 120.0 0.75 0.0 HOH
 6.013
 OD1
 O
ASN B:322 B:2340 143.0 0.894 -136.2 63.5 143.0 0.894 0.0 HOH
 3.769
 C
 O
ASN C:322 C:3340 150.0 0.938 S -71.2 78.5 150.0 0.938 0.0 HOH
 2.656
 OD1
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:322 A:1340 146.0 0.912 -92.9 51.4 146.0 0.912 0.0 HOH
 2.660
 O
 O
ASN B:322 B:2340 149.0 0.931 -93.8 51.3 149.0 0.931 0.0 HOH
 3.312
 N
 O
ASN C:322 C:3340 145.0 0.906 -93.1 51.5 145.0 0.906 0.0 HOH
 5.915
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:322 A:1340 144.0 0.9 S -130.3 7.4 144.0 0.9 0.0 HOH
 3.403
 N
 O
ASN B:322 B:2340 99.0 0.619 -109.1 96.9 99.0 0.619 0.0 HOH
 2.395
 O
 O
ASN C:322 C:3340 91.0 0.569 -93.2 78.5 91.0 0.569 0.0 HOH
 5.110
 OD1
 O
ASN D:322 D:4340 70.0 0.438 -104.4 80.4 70.0 0.438 0.0 HOH
 2.668
 ND2
 O
ASN E:322 E:5340 56.0 0.35 -77.6 -39.5 56.0 0.35 0.0 HOH
 2.890
 O
 O
ASN F:322 F:6340 87.0 0.544 -104.1 82.0 87.0 0.544 0.0 HOH
 2.626
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:320 A:340 149.0 0.931 -81.2 83.2 149.0 0.931 0.0 HOH
 2.708
 O
 O
ASN B:320 B:340 153.0 0.956 -79.6 77.0 153.0 0.956 0.0 HOH
 6.675
 C
 O
ASN C:320 C:340 153.0 0.956 -74.4 78.7 153.0 0.956 0.0 HOH
 8.962
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:320 A:340 127.0 0.794 -72.8 32.4 127.0 0.794 0.0 HOH
 2.750
 CA
 O
ASN B:320 B:340 141.0 0.881 T -138.1 13.0 141.0 0.881 0.0 HOH
 9.007
 C
 O
ASN C:320 C:340 139.0 0.869 -128.8 23.3 139.0 0.869 0.0 HOH
 2.966
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:320 A:340 157.0 0.981 -77.4 11.9 157.0 0.981 0.0 HOH
 2.663
 O
 O
ASN B:320 B:340 156.0 0.975 -81.4 14.8 156.0 0.975 0.0 HOH
 2.704
 ND2
 O
ASN C:320 C:340 156.0 0.975 -74.4 11.1 156.0 0.975 0.0 HOH
 2.536
 ND2
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:320 A:340 144.0 0.9 S -55.4 -14.3 144.0 0.9 0.0 HOH
 3.155
 OD1
 O
ASN B:320 B:340 147.0 0.919 S -56.7 90.3 147.0 0.919 0.0 HOH
 6.432
 O
 O
ASN C:320 C:340 143.0 0.894 -73.8 78.7 143.0 0.894 0.0 HOH
 8.868
 C
 O
ASN D:320 D:340 157.0 0.981 S -51.3 100.6 NA NA NA
ASN E:320 E:340 150.0 0.938 S -143.3 15.1 NA NA NA
ASN F:320 F:340 152.0 0.95 S -71.6 75.5 NA NA NA
ASN G:320 G:340 124.0 0.775 S -62.9 91.0 NA NA NA
ASN H:320 H:340 159.0 0.994 S -44.1 111.8 NA NA NA
ASN I:320 I:340 161.0 1.0 S -91.4 57.2 NA NA NA
ASN J:320 J:340 149.0 0.931 S -53.0 82.1 NA NA NA
ASN K:320 K:340 154.0 0.963 S -62.8 86.8 NA NA NA
ASN L:320 L:340 151.0 0.944 -103.9 25.6 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASN A:320 A:1340 105.0 0.656 -119.1 90.8 105.0 0.656 0.0 HOH
 3.410
 N
 O
ASN B:320 B:2340 111.0 0.694 -124.5 89.7 111.0 0.694 0.0 HOH
 3.728
 N
 O
ASN C:320 C:3340 93.0 0.581 -117.6 86.0 93.0 0.581 0.0 HOH
 2.552
 O
 O
ASN D:320 D:4340 105.0 0.656 -104.7 93.6 NA NA NA
ASN E:320 E:5340 108.0 0.675 -126.3 92.9 NA NA NA
ASN F:320 F:6340 107.0 0.669 -97.0 97.6 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASN A:320 A:1340 119.0 0.744 -74.0 -47.5 119.0 0.744 0.0 HOH
 4.229
 ND2
 O
ASN B:320 B:2340 121.0 0.756 -115.0 -30.7 121.0 0.756 0.0 HOH
 7.234
 ND2
 O
ASN C:320 C:3340 92.0 0.575 -88.0 -49.0 92.0 0.575 0.0 HOH
 3.418
 ND2
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ASN A:320 NA:NA DO NA DO DO DO NA NA NA
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ASN A:320 A:340 90.0 0.562 -102.0 80.4 90.0 0.562 0.0 HOH
 2.777
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASN A:320 A:340 135.0 0.844 -92.6 25.8 135.0 0.844 0.0 HOH
 2.957
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASN A:319 A:340 130.0 0.812 -88.2 2.0 130.0 0.812 0.0 HOH
 2.819
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ASN A:317 NA:NA DO NA DO DO DO NA NA NA
ASN B:317 NA:NA DO NA DO DO DO NA NA NA
ASN C:317 NA:NA DO NA DO DO DO NA NA NA
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 LYS A:317 A:339 162.0 0.81 -111.0 32.9 162.0 0.81 0.0 MAN
HOH
 9.322
2.682
 CE
N
 O6
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ASN A:340 A:340 145.0 0.906 -109.6 45.7