Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55846883 . T A CCDS32450.1:NM_001025195.1:c.1018Agg>Tgg_NP_001020366.1:p.340R>W Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ARG A:321 A:1339 152.0 0.676 T -62.0 64.6 152.0 0.676 0.0 HOH
 2.667
 NE
 O
ARG B:321 B:2339 87.0 0.387 -152.4 51.2 87.0 0.387 0.0 HOH
 3.276
 O
 O
ARG C:321 C:3339 101.0 0.449 T 59.8 29.2 101.0 0.449 0.0 HOH
 2.418
 NE
 O
ARG D:321 D:4339 149.0 0.662 T -107.3 44.3 149.0 0.662 0.0 HOH
 2.821
 O
 O
ARG E:321 E:5339 156.0 0.693 T 46.5 37.7 156.0 0.693 0.0 HOH
 2.804
 NH2
 O
ARG F:321 F:6339 100.0 0.444 T -68.6 61.4 100.0 0.444 0.0 HOH
 3.100
 NE
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:321 A:1339 96.0 0.427 -136.7 22.4 96.0 0.427 0.0 HOH
 2.587
 O
 O
ARG B:321 B:2339 161.0 0.716 T 37.9 44.5 161.0 0.716 0.0 HOH
 3.149
 O
 O
ARG C:321 C:3339 109.0 0.484 T 56.0 17.8 109.0 0.484 0.0 HOH
 2.537
 O
 O
ARG D:321 D:4339 90.0 0.4 S -123.2 18.0 NA NA NA
ARG E:321 E:5339 150.0 0.667 T 51.0 30.4 NA NA NA
ARG F:321 F:6339 115.0 0.511 T 51.3 40.3 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:321 A:1339 182.0 0.809 T -96.5 39.6 182.0 0.809 0.0 HOH
 4.097
 NH2
 O
ARG B:321 B:2339 84.0 0.373 -108.9 -65.5 84.0 0.373 0.0 HOH
 4.389
 C
 O
ARG C:321 C:3339 177.0 0.787 -126.6 133.9 177.0 0.787 0.0 HOH
 6.758
 CG
 O
ARG D:321 D:4339 172.0 0.764 -56.7 119.0 172.0 0.764 0.0 HOH
 6.961
 NH2
 O
ARG E:321 E:5339 121.0 0.538 -97.2 85.8 121.0 0.538 0.0 HOH
 4.766
 CA
 O
ARG F:321 F:6339 108.0 0.48 T 55.5 18.5 108.0 0.48 0.0 HOH
 7.711
 O
 O
ARG G:321 G:1339 122.0 0.542 T -30.0 88.1 NA NA NA
ARG H:321 H:2339 121.0 0.538 S -138.1 34.3 NA NA NA
ARG I:321 I:3339 105.0 0.467 T 57.9 22.7 NA NA NA
ARG J:321 J:4339 159.0 0.707 T -42.8 106.1 NA NA NA
ARG K:321 K:5339 171.0 0.76 T -84.7 87.9 NA NA NA
ARG L:321 L:6339 112.0 0.498 T 43.9 32.9 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:321 A:1339 98.0 0.436 -114.2 26.9 98.0 0.436 0.0 HOH
 5.375
 C
 O
ARG B:321 B:2339 100.0 0.444 -114.8 26.4 100.0 0.444 0.0 HOH
 2.681
 NH2
 O
ARG C:321 C:3339 100.0 0.444 -114.4 26.3 100.0 0.444 0.0 HOH
 4.520
 NH2
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:321 A:1339 92.0 0.409 -113.2 43.8 92.0 0.409 0.0 HOH
 3.930
 NH2
 O
ARG B:321 B:2339 108.0 0.48 -119.3 52.6 108.0 0.48 0.0 HOH
 6.193
 NH1
 O
ARG C:321 C:3339 111.0 0.493 S -107.6 -27.6 111.0 0.493 0.0 HOH
 2.930
 CB
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:321 A:1339 107.0 0.476 -117.1 23.2 107.0 0.476 0.0 HOH
 5.433
 C
 O
ARG B:321 B:2339 108.0 0.48 -117.7 24.0 108.0 0.48 0.0 HOH
 3.086
 C
 O
ARG C:321 C:3339 108.0 0.48 -117.4 23.1 108.0 0.48 0.0 HOH
 7.125
 NH2
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:321 A:1339 104.0 0.462 S -123.5 23.1 104.0 0.462 0.0 HOH
 2.710
 NE
 O
ARG B:321 B:2339 133.0 0.591 T 36.4 46.2 133.0 0.591 0.0 HOH
 2.860
 NH2
 O
ARG C:321 C:3339 109.0 0.484 T 57.4 22.4 109.0 0.484 0.0 HOH
 3.502
 NH1
 O
ARG D:321 D:4339 143.0 0.636 T 55.2 38.1 143.0 0.636 0.0 HOH
 2.685
 NH1
 O
ARG E:321 E:5339 95.0 0.422 T 48.5 31.5 95.0 0.422 0.0 HOH
 2.769
 O
 O
ARG F:321 F:6339 94.0 0.418 T 47.8 38.7 94.0 0.418 0.0 HOH
 3.198
 CG
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:319 A:339 79.0 0.351 -65.4 0.8 79.0 0.351 0.0 HOH
 6.318
 O
 O
ARG B:319 B:339 79.0 0.351 -66.5 1.3 79.0 0.351 0.0 HOH
 7.371
 O
 O
ARG C:319 C:339 79.0 0.351 -66.4 -5.0 79.0 0.351 0.0 HOH
 6.180
 NH1
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:319 A:339 158.0 0.702 -64.8 142.1 158.0 0.702 0.0 HOH
 3.300
 C
 O
ARG B:319 B:339 111.0 0.493 T -83.7 61.4 111.0 0.493 0.0 HOH
 7.083
 NH2
 O
ARG C:319 C:339 101.0 0.449 -79.2 50.0 101.0 0.449 0.0 HOH
 6.941
 C
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:319 A:339 101.0 0.449 -121.7 14.0 101.0 0.449 0.0 HOH
 6.213
 N
 O
ARG B:319 B:339 99.0 0.44 -123.2 17.3 99.0 0.44 0.0 HOH
 6.262
 NH1
 O
ARG C:319 C:339 94.0 0.418 -121.7 11.0 94.0 0.418 0.0 HOH
 2.767
 NH2
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:319 A:339 105.0 0.467 -106.9 -5.1 105.0 0.467 0.0 HOH
 4.529
 N
 O
ARG B:319 B:339 130.0 0.578 -98.4 -37.1 130.0 0.578 0.0 HOH
 8.074
 O
 O
ARG C:319 C:339 121.0 0.538 -77.9 -10.5 121.0 0.538 0.0 HOH
 8.082
 O
 O
ARG D:319 D:339 97.0 0.431 -65.2 -66.2 NA NA NA
ARG E:319 E:339 179.0 0.796 S -122.9 51.9 NA NA NA
ARG F:319 F:339 98.0 0.436 -72.0 -29.1 NA NA NA
ARG G:319 G:339 189.0 0.84 S -78.9 -46.9 NA NA NA
ARG H:319 H:339 119.0 0.529 -107.7 -83.9 NA NA NA
ARG I:319 I:339 150.0 0.667 -130.4 -7.5 NA NA NA
ARG J:319 J:339 90.0 0.4 -71.4 -38.0 NA NA NA
ARG K:319 K:339 96.0 0.427 -71.0 -55.3 NA NA NA
ARG L:319 L:339 115.0 0.511 -110.9 29.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:319 A:1339 107.0 0.476 T 50.9 23.2 107.0 0.476 0.0 HOH
 2.425
 NH2
 O
ARG B:319 B:2339 105.0 0.467 T 46.2 31.9 105.0 0.467 0.0 HOH
 3.271
 O
 O
ARG C:319 C:3339 106.0 0.471 T 41.1 32.9 106.0 0.471 0.0 HOH
 2.789
 O
 O
ARG D:319 D:4339 101.0 0.449 T 56.4 16.6 NA NA NA
ARG E:319 E:5339 104.0 0.462 T 45.4 36.4 NA NA NA
ARG F:319 F:6339 97.0 0.431 58.7 8.5 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:319 A:1339 105.0 0.467 53.2 3.4 105.0 0.467 0.0 HOH
 6.971
 C
 O
ARG B:319 B:2339 111.0 0.493 T 35.9 47.6 111.0 0.493 0.0 HOH
 2.599
 NE
 O
ARG C:319 C:3339 107.0 0.476 T 50.4 27.4 107.0 0.476 0.0 HOH
 3.318
 NE
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ARG A:319 NA:NA DO NA DO DO DO NA NA NA
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ARG A:319 A:339 151.0 0.671 T 58.7 34.9 151.0 0.671 0.0 HOH
 2.875
 NH1
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:319 A:339 136.0 0.604 T 47.2 49.3 136.0 0.604 0.0 HOH
 2.814
 NH2
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:318 A:339 142.0 0.631 T 61.1 30.6 142.0 0.631 0.0 HOH
 3.338
 NH2
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ARG A:316 A:1339 167.0 0.742 -91.8 360.0 167.0 0.742 0.0
ARG B:316 NA:NA DO NA DO DO DO NA NA NA
ARG C:316 NA:NA DO NA DO DO DO NA NA NA
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 LYS A:316 A:338 97.0 0.485 T 55.5 18.0 97.0 0.485 0.0 MAN
MAN
HOH
 8.056
7.730
3.430
 N
CE
N
 O4
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ARG A:339 A:339 141.0 0.627 T 55.4 25.4