Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55850852 . T A CCDS32450.1:NM_001025195.1:c.929cAg>cTg_NP_001020366.1:p.310Q>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLN A:291 A:1309 147.0 0.817 S -114.7 144.7 50.0 0.278 0.539 F:P23141:0.539
 HOH
 2.812
 O
 O
GLN B:291 B:2309 144.0 0.8 S -116.1 141.9 57.0 0.317 0.483 E:P23141:0.483
 HOH
 2.742
 OE1
 O
GLN C:291 C:3309 154.0 0.856 S -119.0 149.3 23.0 0.128 0.728 D:P23141:0.728
 HOH
 2.885
 OE1
 O
GLN D:291 D:4309 147.0 0.817 S -122.4 134.1 43.0 0.239 0.578 C:P23141:0.578
 HOH
 3.762
 C
 O
GLN E:291 E:5309 143.0 0.794 S -118.0 133.1 54.0 0.3 0.494 B:P23141:0.494
 HOH
 3.016
 O
 O
GLN F:291 F:6309 152.0 0.844 S -114.6 153.3 23.0 0.128 0.716 A:P23141:0.717
 HOH
 2.651
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLN A:291 A:1309 171.0 0.95 S -91.7 99.4 171.0 0.95 0.0 HOH
 3.826
 N
 O
GLN B:291 B:2309 160.0 0.889 S -120.1 144.7 160.0 0.889 0.0 HOH
 6.037
 O
 O
GLN C:291 C:3309 136.0 0.756 S -100.7 141.7 136.0 0.756 0.0 HOH
 3.294
 OE1
 O
GLN D:291 D:4309 155.0 0.861 S -109.6 117.3 NA NA NA
GLN E:291 E:5309 137.0 0.761 S -101.8 146.7 NA NA NA
GLN F:291 F:6309 163.0 0.906 S -82.9 114.6 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLN A:291 A:1309 146.0 0.811 S -117.4 157.6 46.0 0.256 0.555 F:P23141:0.556
 HOH
 3.333
 CG
 O
GLN B:291 B:2309 152.0 0.844 S -93.6 133.8 38.0 0.211 0.633 E:P23141:0.633
 HOH
 3.962
 OE1
 O
GLN C:291 C:3309 139.0 0.772 S -107.2 133.8 22.0 0.122 0.65 D:P23141:0.65
 NLX
HOH
 8.103
5.011
 NE2
NE2
 C19
O
GLN D:291 D:4309 139.0 0.772 S -125.3 151.9 59.0 0.328 0.444 C:P23141:0.444
 HOH
 3.301
 O
 O
GLN E:291 E:5309 159.0 0.883 S -112.3 148.9 46.0 0.256 0.627 B:P23141:0.628
 HOH
 2.495
 NE2
 O
GLN F:291 F:6309 148.0 0.822 S -125.5 155.7 24.0 0.133 0.689 A:P23141:0.689
 NLX
HOH
 8.583
2.793
 NE2
O
 C19
O
GLN G:291 G:1309 148.0 0.822 S -122.9 134.7 NA NA NA
GLN H:291 H:2309 158.0 0.878 S -69.9 130.6 NA NA NA
GLN I:291 I:3309 142.0 0.789 S -125.5 149.1 NA NA NA
GLN J:291 J:4309 169.0 0.939 S -80.0 135.9 NA NA NA
GLN K:291 K:5309 151.0 0.839 S -122.3 143.6 NA NA NA
GLN L:291 L:6309 150.0 0.833 S -114.2 158.9 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLN A:291 A:1309 137.0 0.761 S -102.3 -174.8 137.0 0.761 0.0 HOH
 2.688
 CB
 O
GLN B:291 B:2309 138.0 0.767 S -102.0 -174.3 138.0 0.767 0.0 HOH
 7.556
 CA
 O
GLN C:291 C:3309 139.0 0.772 S -103.1 -175.4 139.0 0.772 0.0 HOH
 4.274
 C
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLN A:291 A:1309 145.0 0.806 S -112.9 169.6 145.0 0.806 0.0 HOH
 3.336
 CA
 O
GLN B:291 B:2309 165.0 0.917 S -79.0 92.1 165.0 0.917 0.0 HOH
 3.243
 N
 O
GLN C:291 C:3309 163.0 0.906 S -133.5 121.4 163.0 0.906 0.0 HOH
 2.701
 NE2
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLN A:291 A:1309 139.0 0.772 S -83.2 174.7 139.0 0.772 0.0 HOH
 2.764
 NE2
 O
GLN B:291 B:2309 138.0 0.767 S -83.5 174.6 138.0 0.767 0.0 HOH
 9.689
 CA
 O
GLN C:291 C:3309 138.0 0.767 S -83.9 174.8 138.0 0.767 0.0 HOH
 4.057
 C
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLN A:291 A:1309 143.0 0.794 S -121.9 132.0 39.0 0.217 0.577 F:P23141:0.578
 COA
HOH
 7.998
2.653
 N
O
 N6A
O
GLN B:291 B:2309 153.0 0.85 S -123.7 140.5 17.0 0.094 0.756 D:P23141:0.756
 COA
HOH
 7.475
3.012
 N
CG
 N6A
O
GLN C:291 C:3309 148.0 0.822 S -111.9 143.4 57.0 0.317 0.505 E:P23141:0.506
 COA
HOH
 7.403
2.588
 N
O
 N6A
O
GLN D:291 D:4309 146.0 0.811 S -121.3 143.9 75.0 0.417 0.394 B:P23141:0.394
 COA
HOH
 6.658
3.060
 N
CD
 N6A
O
GLN E:291 E:5309 151.0 0.839 S -116.9 140.0 18.0 0.1 0.739 C:P23141:0.739
 COA
HOH
 7.415
2.892
 N
O
 N6A
O
GLN F:291 F:6309 142.0 0.789 S -121.0 136.3 65.0 0.361 0.428 A:P23141:0.428
 COA
HOH
 7.497
2.832
 N
OE1
 N6A
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLN A:289 A:309 172.0 0.956 S -130.3 110.8 172.0 0.956 0.0 HOH
 4.913
 O
 O
GLN B:289 B:309 175.0 0.972 S -126.3 100.2 175.0 0.972 0.0 HOH
 6.355
 NE2
 O
GLN C:289 C:309 174.0 0.967 S -131.0 101.2 174.0 0.967 0.0 HOH
 2.607
 OE1
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLN A:289 A:309 155.0 0.861 S -110.0 179.0 155.0 0.861 0.0
GLN B:289 B:309 161.0 0.894 S -76.6 176.6 161.0 0.894 0.0 HOH
 7.280
 N
 O
GLN C:289 C:309 148.0 0.822 S -83.0 145.8 148.0 0.822 0.0 HOH
 2.524
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLN A:289 A:309 147.0 0.817 S -102.5 150.3 147.0 0.817 0.0 HOH
 2.766
 OE1
 O
GLN B:289 B:309 150.0 0.833 S -99.4 148.6 150.0 0.833 0.0 HOH
 2.875
 O
 O
GLN C:289 C:309 151.0 0.839 S -100.3 150.9 151.0 0.839 0.0 HOH
 3.197
 CB
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLN A:289 A:309 150.0 0.833 S -76.3 -170.6 150.0 0.833 0.0 HOH
 2.880
 OE1
 O
GLN B:289 B:309 150.0 0.833 S -67.5 132.2 150.0 0.833 0.0
GLN C:289 C:309 167.0 0.928 S -120.5 132.8 167.0 0.928 0.0 HOH
 5.178
 C
 O
GLN D:289 D:309 138.0 0.767 S -112.4 148.4 NA NA NA
GLN E:289 E:309 150.0 0.833 S -65.6 -175.3 NA NA NA
GLN F:289 F:309 183.0 1.0 S -136.0 42.0 NA NA NA
GLN G:289 G:309 181.0 1.0 S -87.7 120.9 NA NA NA
GLN H:289 H:309 136.0 0.756 S -130.9 160.2 NA NA NA
GLN I:289 I:309 152.0 0.844 S -59.7 155.1 NA NA NA
GLN J:289 J:309 167.0 0.928 S -133.2 59.5 NA NA NA
GLN K:289 K:309 137.0 0.761 S -59.7 159.0 NA NA NA
GLN L:289 L:309 154.0 0.856 S -66.5 138.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLN A:289 A:1309 142.0 0.789 S -103.7 171.8 142.0 0.789 0.0 HOH
 2.804
 NE2
 O
GLN B:289 B:2309 139.0 0.772 S -97.9 143.6 139.0 0.772 0.0 HOH
 3.669
 C
 O
GLN C:289 C:3309 144.0 0.8 S -128.8 140.4 144.0 0.8 0.0 HOH
 2.679
 NE2
 O
GLN D:289 D:4309 163.0 0.906 S -108.7 175.5 NA NA NA
GLN E:289 E:5309 146.0 0.811 S -100.7 131.7 NA NA NA
GLN F:289 F:6309 158.0 0.878 S -126.9 128.4 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLN A:289 A:1309 168.0 0.933 S -92.1 -60.9 168.0 0.933 0.0 HOH
 3.299
 O
 O
GLN B:289 B:2309 157.0 0.872 S -90.6 116.9 157.0 0.872 0.0 HOH
 4.630
 O
 O
GLN C:289 C:3309 152.0 0.844 S -103.5 125.8 152.0 0.844 0.0 HOH
 3.981
 N
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLN A:289 A:309 146.0 0.811 S -109.7 139.1 54.0 0.3 0.511 A:P23141:0.511
 HOH
 3.477
 C
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLN A:289 A:309 162.0 0.9 S -136.6 139.5 162.0 0.9 0.0 HOH
 4.767
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLN A:289 A:309 141.0 0.783 S -114.9 153.1 141.0 0.783 0.0 HOH
 7.320
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLN A:288 A:309 126.0 0.7 S -117.1 159.7 126.0 0.7 0.0 HOH
 4.211
 C
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLN A:286 NA:NA DO NA DO DO DO NA NA NA
GLN B:286 NA:NA DO NA DO DO DO NA NA NA
GLN C:286 NA:NA DO NA DO DO DO NA NA NA
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 VAL A:286 A:308 124.0 0.8 S -60.8 141.0 124.0 0.8 0.0 HOH
 5.702
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLN A:309 A:309 160.0 0.889 S -115.0 155.3