Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55850874 . T A CCDS32450.1:NM_001025195.1:c.907Aaa>Taa_NP_001020366.1:p.303K>* Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 LYS A:284 A:1302 137.0 0.685 T 57.8 58.5 100.0 0.5 0.185 F:P23141:0.185
 HOH
 2.631
 NZ
 O
LYS B:284 B:2302 149.0 0.745 T 60.1 57.5 92.0 0.46 0.285 E:P23141:0.285
 THA
HOH
 9.344
2.511
 O
NZ
 C11
O
LYS C:284 C:3302 148.0 0.74 T 58.9 56.2 78.0 0.39 0.35 D:P23141:0.35
 HOH
 3.157
 CE
 O
LYS D:284 D:4302 156.0 0.78 T 59.6 51.4 74.0 0.37 0.41 C:P23141:0.41
 THA
HOH
 9.744
3.530
 O
C
 C2
O
LYS E:284 E:5302 150.0 0.75 T 57.1 58.0 98.0 0.49 0.26 B:P23141:0.26
 THA
THA
HOH
 9.247
9.797
2.661
 NZ
O
NZ
 C12
N15
O
LYS F:284 F:6302 152.0 0.76 T 51.5 57.0 64.0 0.32 0.44 A:P23141:0.44
 THA
HOH
 9.248
3.034
 O
CE
 C1
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LYS A:284 A:1302 151.0 0.755 T 47.8 53.1 151.0 0.755 0.0 HOH
 3.006
 O
 O
LYS B:284 B:2302 151.0 0.755 T 48.2 58.1 151.0 0.755 0.0 HTQ
HOH
 9.639
3.172
 C
C
 C17
O
LYS C:284 C:3302 150.0 0.75 T 49.1 65.8 150.0 0.75 0.0 HTQ
HOH
 9.250
2.825
 C
O
 C19
O
LYS D:284 D:4302 157.0 0.785 T 46.2 50.1 NA NA NA
LYS E:284 E:5302 152.0 0.76 T 43.6 56.1 NA NA NA
LYS F:284 F:6302 153.0 0.765 T 42.9 68.2 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LYS A:284 A:1302 149.0 0.745 T 49.9 57.1 96.0 0.48 0.265 F:P23141:0.265
 NLX
HOH
 8.386
3.047
 O
CG
 C20
O
LYS B:284 B:2302 150.0 0.75 T 58.8 52.2 110.0 0.55 0.2 E:P23141:0.2
 NLX
NLX
HOH
 6.632
6.881
5.329
 O
NZ
CD
 C19
C19
O
LYS C:284 C:3302 152.0 0.76 T 66.9 51.1 72.0 0.36 0.4 D:P23141:0.4
 NLX
NLX
HOH
 8.100
8.155
6.627
 O
CE
CD
 C17
C19
O
LYS D:284 D:4302 151.0 0.755 T 52.8 49.5 93.0 0.465 0.29 C:P23141:0.29
 NLX
HOH
 7.906
5.480
 O
NZ
 C20
O
LYS E:284 E:5302 154.0 0.77 T 49.0 52.0 84.0 0.42 0.35 B:P23141:0.35
 NLX
HOH
 7.819
5.554
 O
NZ
 C19
O
LYS F:284 F:6302 147.0 0.735 T 55.5 56.4 69.0 0.345 0.39 A:P23141:0.39
 NLX
NLX
HOH
 6.913
8.637
5.875
 NZ
O
CE
 C19
C1
O
LYS G:284 G:1302 153.0 0.765 T 44.9 66.7 NA NA NA
LYS H:284 H:2302 158.0 0.79 T 35.2 53.6 NA NA NA
LYS I:284 I:3302 161.0 0.805 44.0 46.4 NA NA NA
LYS J:284 J:4302 133.0 0.665 T 48.6 64.4 NA NA NA
LYS K:284 K:5302 154.0 0.77 T 56.8 56.8 NA NA NA
LYS L:284 L:6302 147.0 0.735 T 41.9 35.0 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:284 A:1302 149.0 0.745 52.3 85.9 149.0 0.745 0.0 PLM
HOH
 3.508
4.549
 CA
O
 CG
O
LYS B:284 B:2302 161.0 0.805 T 36.2 69.6 161.0 0.805 0.0 PLM
HOH
 8.448
8.869
 C
C
 CB
O
LYS C:284 C:3302 154.0 0.77 T 53.8 52.3 154.0 0.77 0.0 PLM
HOH
 7.220
3.688
 CA
C
 CG
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:284 A:1302 156.0 0.78 T 57.2 49.6 156.0 0.78 0.0 HOH
 3.451
 N
 O
LYS B:284 B:2302 161.0 0.805 43.3 75.6 161.0 0.805 0.0 HOH
 5.059
 O
 O
LYS C:284 C:3302 156.0 0.78 T 52.1 66.9 156.0 0.78 0.0 HOH
 3.373
 N
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:284 A:1302 152.0 0.76 T 51.0 66.9 152.0 0.76 0.0 TCH
HOH
 7.873
2.879
 C
C
 O24
O
LYS B:284 B:2302 153.0 0.765 T 45.5 46.6 153.0 0.765 0.0 TCH
HOH
 8.553
5.685
 O
C
 O3S
O
LYS C:284 C:3302 168.0 0.84 50.6 104.8 168.0 0.84 0.0 TCH
HOH
 8.167
5.182
 CA
CA
 O3S
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:284 A:1302 101.0 0.505 T 53.0 49.7 60.0 0.3 0.205 F:P23141:0.205
 COA
COA
HOH
 3.089
2.694
2.517
 C
CB
O
 O2A
O2B
O
LYS B:284 B:2302 100.0 0.5 T 61.8 40.4 62.0 0.31 0.19 D:P23141:0.19
 COA
COA
HOH
 2.898
2.866
2.577
 C
CB
O
 O2A
O2B
O
LYS C:284 C:3302 105.0 0.525 T 49.0 61.3 61.0 0.305 0.22 E:P23141:0.22
 COA
COA
HOH
 2.820
2.742
2.649
 C
CB
O
 O2A
O2B
O
LYS D:284 D:4302 104.0 0.52 T 56.3 54.1 59.0 0.295 0.225 B:P23141:0.225
 COA
COA
HOH
 2.535
3.416
2.580
 CB
O
O
 O2B
O2A
O
LYS E:284 E:5302 99.0 0.495 T 54.4 44.3 62.0 0.31 0.185 C:P23141:0.185
 COA
COA
HOH
 2.641
3.230
2.547
 CB
C
NZ
 O2B
O2A
O
LYS F:284 F:6302 103.0 0.515 T 50.9 60.4 57.0 0.285 0.23 A:P23141:0.23
 COA
COA
HOH
 2.680
2.876
2.610
 CB
C
O
 O2B
O2A
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:282 A:302 164.0 0.82 T 47.5 59.9 164.0 0.82 0.0 CTX
HOH
 6.026
3.774
 C
C
 C21
O
LYS B:282 B:302 167.0 0.835 T 36.1 68.3 167.0 0.835 0.0 CTX
HOH
 7.833
3.070
 C
NZ
 C22
O
LYS C:282 C:302 170.0 0.85 T 49.9 55.0 170.0 0.85 0.0 CTX
HOH
 7.982
4.877
 C
O
 CB1
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:282 A:302 151.0 0.755 T 48.5 52.4 151.0 0.755 0.0 HOH
 8.040
 N
 O
LYS B:282 B:302 157.0 0.785 T 42.2 56.0 157.0 0.785 0.0 HOH
 4.578
 O
 O
LYS C:282 C:302 159.0 0.795 T 71.2 57.7 159.0 0.795 0.0 HOH
 3.222
 N
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:282 A:302 163.0 0.815 T 48.9 65.5 163.0 0.815 0.0 HOH
 2.428
 O
 O
LYS B:282 B:302 166.0 0.83 T 51.6 65.0 166.0 0.83 0.0 HOH
 2.501
 O
 O
LYS C:282 C:302 164.0 0.82 T 52.3 62.2 164.0 0.82 0.0 HOH
 2.228
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:282 A:302 148.0 0.74 T 61.2 56.4 148.0 0.74 0.0 HOH
 7.648
 CD
 O
LYS B:282 B:302 141.0 0.705 T 41.0 83.5 141.0 0.705 0.0 HOH
 8.222
 O
 O
LYS C:282 C:302 152.0 0.76 T 68.9 56.2 152.0 0.76 0.0 HOH
 9.823
 N
 O
LYS D:282 D:302 161.0 0.805 T 54.3 47.2 NA NA NA
LYS E:282 E:302 155.0 0.775 T 43.5 52.8 NA NA NA
LYS F:282 F:302 134.0 0.67 T 65.7 42.5 NA NA NA
LYS G:282 G:302 143.0 0.715 T 61.1 56.3 NA NA NA
LYS H:282 H:302 147.0 0.735 T 62.0 50.4 NA NA NA
LYS I:282 I:302 145.0 0.725 T 17.5 86.7 NA NA NA
LYS J:282 J:302 135.0 0.675 T 61.7 44.2 NA NA NA
LYS K:282 K:302 156.0 0.78 T 54.5 58.6 NA NA NA
LYS L:282 L:302 145.0 0.725 T 32.3 64.0 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LYS A:282 A:1302 154.0 0.77 T 49.0 56.4 154.0 0.77 0.0 HOH
 4.209
 CB
 O
LYS B:282 B:2302 158.0 0.79 T 44.5 64.2 158.0 0.79 0.0 HOH
 3.872
 C
 O
LYS C:282 C:3302 159.0 0.795 T 55.9 55.3 159.0 0.795 0.0 HOH
 2.573
 O
 O
LYS D:282 D:4302 130.0 0.65 T 51.7 57.9 NA NA NA
LYS E:282 E:5302 154.0 0.77 T 48.9 57.0 NA NA NA
LYS F:282 F:6302 162.0 0.81 T 59.2 52.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LYS A:282 A:1302 124.0 0.62 T 37.4 59.4 124.0 0.62 0.0 HOH
 3.987
 CA
 O
LYS B:282 B:2302 138.0 0.69 T 54.7 57.5 138.0 0.69 0.0 HOH
 3.015
 C
 O
LYS C:282 C:3302 152.0 0.76 T 55.9 51.9 152.0 0.76 0.0 HOH
 3.226
 CE
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 LYS A:282 A:302 158.0 0.79 T 52.7 63.2 82.0 0.41 0.38 A:P23141:0.38
 HOH
 3.047
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 LYS A:282 A:302 140.0 0.7 T 55.9 49.6 140.0 0.7 0.0 HOH
 4.018
 C
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LYS A:282 A:302 141.0 0.705 T 52.9 60.8 141.0 0.705 0.0 HOH
 3.112
 C
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LYS A:281 A:302 140.0 0.7 T 46.2 58.9 140.0 0.7 0.0 HOH
 3.787
 C
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 LYS A:279 A:1302 187.0 0.935 T 52.2 45.5 187.0 0.935 0.0 HOH
 4.685
 O
 O
LYS B:279 B:2302 156.0 0.78 T 51.6 46.2 156.0 0.78 0.0 HOH
 8.545
 N
 O
LYS C:279 C:3302 180.0 0.9 T 50.9 46.2 180.0 0.9 0.0 WW2
HOH
 9.508
9.909
 O
CA
 C4
O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 LYS A:279 A:301 118.0 0.59 T 49.2 65.1 118.0 0.59 0.0 HOH
 2.975
 NZ
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 LYS A:302 A:302 142.0 0.71 T 53.1 43.2