Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55853460 . G A CCDS32450.1:NM_001025195.1:c.893aCg>aTg_NP_001020366.1:p.298T>M Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 THR A:279 A:1297 5.0 0.036 H -64.3 -42.8 5.0 0.036 0.0 HOH
 3.288
 OG1
 O
THR B:279 B:2297 4.0 0.029 H -67.8 -37.7 4.0 0.029 0.0 HOH
 3.186
 OG1
 O
THR C:279 C:3297 6.0 0.043 H -66.1 -40.4 6.0 0.043 0.0 HOH
 3.269
 OG1
 O
THR D:279 D:4297 5.0 0.036 H -65.1 -42.1 5.0 0.036 0.0 HOH
 3.833
 OG1
 O
THR E:279 E:5297 6.0 0.043 H -64.9 -39.0 6.0 0.043 0.0 HOH
 3.355
 OG1
 O
THR F:279 F:6297 7.0 0.05 H -69.3 -40.3 7.0 0.05 0.0 HOH
 3.355
 OG1
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:279 A:1297 5.0 0.036 H -65.9 -40.9 5.0 0.036 0.0 HOH
 2.989
 OG1
 O
THR B:279 B:2297 5.0 0.036 H -63.3 -42.8 5.0 0.036 0.0 HOH
 5.942
 N
 O
THR C:279 C:3297 5.0 0.036 H -68.6 -38.6 5.0 0.036 0.0 HOH
 3.443
 OG1
 O
THR D:279 D:4297 5.0 0.036 H -68.2 -44.0 NA NA NA
THR E:279 E:5297 5.0 0.036 H -60.0 -43.7 NA NA NA
THR F:279 F:6297 4.0 0.029 H -65.2 -44.4 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:279 A:1297 6.0 0.043 H -72.2 -37.2 6.0 0.043 0.0 HOH
 6.715
 C
 O
THR B:279 B:2297 4.0 0.029 H -73.3 -45.0 4.0 0.029 0.0 HOH
 5.785
 N
 O
THR C:279 C:3297 5.0 0.036 H -69.9 -51.0 5.0 0.036 0.0 HOH
 6.612
 C
 O
THR D:279 D:4297 5.0 0.036 H -70.7 -46.8 5.0 0.036 0.0 HOH
 6.594
 C
 O
THR E:279 E:5297 3.0 0.021 H -67.1 -44.8 3.0 0.021 0.0 HOH
 5.412
 N
 O
THR F:279 F:6297 5.0 0.036 H -77.5 -46.6 5.0 0.036 0.0 HOH
 6.519
 C
 O
THR G:279 G:1297 6.0 0.043 H -71.1 -49.1 NA NA NA
THR H:279 H:2297 7.0 0.05 H -74.3 -42.5 NA NA NA
THR I:279 I:3297 5.0 0.036 H -80.3 -43.2 NA NA NA
THR J:279 J:4297 4.0 0.029 H -73.8 -52.2 NA NA NA
THR K:279 K:5297 5.0 0.036 H -68.3 -51.6 NA NA NA
THR L:279 L:6297 6.0 0.043 H -71.2 -54.4 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:279 A:1297 6.0 0.043 H -55.0 -47.6 6.0 0.043 0.0 PLM
HOH
 6.375
6.459
 O
C
 CG
O
THR B:279 B:2297 3.0 0.021 H -54.8 -47.0 3.0 0.021 0.0 HOH
 6.633
 C
 O
THR C:279 C:3297 5.0 0.036 H -54.4 -43.1 5.0 0.036 0.0 HOH
 5.276
 N
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:279 A:1297 7.0 0.05 H -68.3 -38.8 7.0 0.05 0.0 HOH
 5.942
 O
 O
THR B:279 B:2297 4.0 0.029 H -56.8 -47.3 4.0 0.029 0.0 HOH
 2.693
 OG1
 O
THR C:279 C:3297 7.0 0.05 H -63.0 -37.6 7.0 0.05 0.0 HOH
 3.147
 OG1
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:279 A:1297 6.0 0.043 H -62.3 -40.0 6.0 0.043 0.0 HOH
 6.347
 OG1
 O
THR B:279 B:2297 6.0 0.043 H -63.8 -42.3 6.0 0.043 0.0 HOH
 8.876
 C
 O
THR C:279 C:3297 6.0 0.043 H -62.5 -41.3 6.0 0.043 0.0 HOH
 6.441
 C
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:279 A:1297 5.0 0.036 H -59.3 -42.3 5.0 0.036 0.0 COA
COA
HOH
 9.176
7.685
3.134
 O
O
OG1
 O9A
O8A
O
THR B:279 B:2297 4.0 0.029 H -67.2 -41.4 4.0 0.029 0.0 COA
COA
HOH
 8.602
7.868
3.174
 O
O
OG1
 O9A
O8A
O
THR C:279 C:3297 5.0 0.036 H -66.3 -42.6 5.0 0.036 0.0 COA
COA
HOH
 8.720
7.999
3.221
 O
O
OG1
 O9A
O8A
O
THR D:279 D:4297 5.0 0.036 H -66.4 -41.8 5.0 0.036 0.0 COA
COA
HOH
 7.477
9.061
3.356
 O
O
OG1
 O8A
O9A
O
THR E:279 E:5297 6.0 0.043 H -64.8 -41.0 6.0 0.043 0.0 COA
COA
HOH
 7.328
9.262
3.277
 O
O
OG1
 O8A
O9A
O
THR F:279 F:6297 5.0 0.036 H -65.1 -38.4 5.0 0.036 0.0 COA
COA
HOH
 7.932
8.735
3.198
 O
O
OG1
 O8A
O9A
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:277 A:297 6.0 0.043 H -62.9 -38.5 6.0 0.043 0.0 HOH
 6.774
 C
 O
THR B:277 B:297 5.0 0.036 H -70.3 -42.7 5.0 0.036 0.0 HOH
 3.097
 OG1
 O
THR C:277 C:297 5.0 0.036 H -69.3 -40.4 5.0 0.036 0.0 HOH
 8.917
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:277 A:297 4.0 0.029 H -71.1 -39.6 4.0 0.029 0.0 HOH
 3.010
 OG1
 O
THR B:277 B:297 3.0 0.021 H -62.3 -44.0 3.0 0.021 0.0 HOH
 5.633
 OG1
 O
THR C:277 C:297 9.0 0.064 H -59.4 -40.6 9.0 0.064 0.0 HOH
 4.567
 N
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:277 A:297 5.0 0.036 H -63.6 -44.8 5.0 0.036 0.0 HOH
 5.882
 O
 O
THR B:277 B:297 5.0 0.036 H -63.8 -42.3 5.0 0.036 0.0 HOH
 6.237
 O
 O
THR C:277 C:297 5.0 0.036 H -63.5 -44.2 5.0 0.036 0.0 HOH
 3.961
 OG1
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:277 A:297 4.0 0.029 H -72.9 -35.2 4.0 0.029 0.0 HOH
 8.159
 C
 O
THR B:277 B:297 2.0 0.014 H -65.9 -45.1 2.0 0.014 0.0
THR C:277 C:297 4.0 0.029 H -51.7 -41.4 4.0 0.029 0.0 HOH
 4.124
 OG1
 O
THR D:277 D:297 6.0 0.043 H -73.5 -25.8 NA NA NA
THR E:277 E:297 2.0 0.014 H -74.1 -50.2 NA NA NA
THR F:277 F:297 2.0 0.014 H -52.1 -39.4 NA NA NA
THR G:277 G:297 6.0 0.043 H -51.7 -39.3 NA NA NA
THR H:277 H:297 4.0 0.029 H -63.3 -36.9 NA NA NA
THR I:277 I:297 1.0 0.007 H -72.6 -40.2 NA NA NA
THR J:277 J:297 4.0 0.029 H -45.9 -41.1 NA NA NA
THR K:277 K:297 4.0 0.029 H -84.0 -33.1 NA NA NA
THR L:277 L:297 2.0 0.014 H -80.1 -33.8 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:277 A:1297 6.0 0.043 H -59.9 -40.8 6.0 0.043 0.0 HOH
 6.456
 C
 O
THR B:277 B:2297 3.0 0.021 H -61.3 -43.9 3.0 0.021 0.0 HOH
 4.241
 OG1
 O
THR C:277 C:3297 5.0 0.036 H -65.3 -37.3 5.0 0.036 0.0 HOH
 6.327
 O
 O
THR D:277 D:4297 7.0 0.05 H -63.7 -41.0 NA NA NA
THR E:277 E:5297 5.0 0.036 H -59.0 -44.8 NA NA NA
THR F:277 F:6297 5.0 0.036 H -61.0 -41.8 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:277 A:1297 8.0 0.057 H -60.6 -45.8 8.0 0.057 0.0 HOH
 5.569
 N
 O
THR B:277 B:2297 4.0 0.029 H -59.5 -41.8 4.0 0.029 0.0 HOH
 3.069
 OG1
 O
THR C:277 C:3297 6.0 0.043 H -56.5 -41.8 6.0 0.043 0.0 HOH
 3.242
 OG1
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 THR A:277 A:297 4.0 0.029 H -54.4 -47.5 4.0 0.029 0.0 HOH
 3.332
 OG1
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 THR A:277 A:297 4.0 0.029 H -52.3 -46.0 4.0 0.029 0.0 HOH
 3.507
 OG1
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:277 A:297 5.0 0.036 H -65.0 -46.4 5.0 0.036 0.0 HOH
 2.688
 OG1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:276 A:297 7.0 0.05 H -55.1 -43.2 7.0 0.05 0.0 HOH
 6.021
 O
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 THR A:274 A:1297 7.0 0.05 H -71.6 -42.3 7.0 0.05 0.0 HOH
 6.624
 C
 O
THR B:274 B:2297 6.0 0.043 H -72.4 -42.0 6.0 0.043 0.0 HOH
 6.201
 C
 O
THR C:274 C:3297 7.0 0.05 H -71.6 -43.2 7.0 0.05 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 VAL A:274 A:296 5.0 0.032 H -63.3 -44.5 5.0 0.032 0.0 HOH
 5.849
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 THR A:297 A:297 4.0 0.029 H -58.7 -47.2