Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55853481 . G A CCDS32450.1:NM_001025195.1:c.872aCg>aTg_NP_001020366.1:p.291T>M Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 THR A:272 A:1290 74.0 0.529 -81.4 163.7 70.0 0.5 0.029 B:P23141:0.029
 HOH
 3.797
 N
 O
THR B:272 B:2290 72.0 0.514 -77.6 163.2 72.0 0.514 0.0 HOH
 3.038
 OG1
 O
THR C:272 C:3290 77.0 0.55 -80.7 161.6 71.0 0.507 0.043 A:P23141:0.043
 HOH
 3.147
 OG1
 O
THR D:272 D:4290 76.0 0.543 -81.9 167.5 69.0 0.493 0.05 E:P23141:0.05
 HOH
 3.390
 CB
 O
THR E:272 E:5290 70.0 0.5 -78.9 166.4 70.0 0.5 0.0 HOH
 2.814
 OG1
 O
THR F:272 F:6290 73.0 0.521 -84.6 168.6 69.0 0.493 0.028 D:P23141:0.029
 HOH
 3.503
 CB
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:272 A:1290 62.0 0.443 -80.1 170.0 62.0 0.443 0.0 HOH
 2.572
 OG1
 O
THR B:272 B:2290 56.0 0.4 -73.1 159.0 56.0 0.4 0.0 HOH
 3.077
 OG1
 O
THR C:272 C:3290 72.0 0.514 -89.0 160.0 64.0 0.457 0.057 A:P23141:0.057
 HOH
 3.467
 OG1
 O
THR D:272 D:4290 65.0 0.464 -78.1 158.9 NA NA NA
THR E:272 E:5290 63.0 0.45 -75.1 162.0 NA NA NA
THR F:272 F:6290 62.0 0.443 -79.4 170.7 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:272 A:1290 73.0 0.521 -74.9 167.3 73.0 0.521 0.0 HOH
 2.993
 OG1
 O
THR B:272 B:2290 67.0 0.479 -84.5 166.5 67.0 0.479 0.0 HOH
 5.292
 OG1
 O
THR C:272 C:3290 71.0 0.507 -72.3 170.0 71.0 0.507 0.0 HOH
 6.115
 CA
 O
THR D:272 D:4290 74.0 0.529 -83.7 168.4 66.0 0.471 0.058 E:P23141:0.057
 HOH
 7.317
 C
 O
THR E:272 E:5290 70.0 0.5 -74.0 172.0 70.0 0.5 0.0 HOH
 2.494
 OG1
 O
THR F:272 F:6290 61.0 0.436 -82.0 160.9 61.0 0.436 0.0 HOH
 2.678
 OG1
 O
THR G:272 G:1290 74.0 0.529 -68.7 162.5 NA NA NA
THR H:272 H:2290 74.0 0.529 -90.6 161.9 NA NA NA
THR I:272 I:3290 71.0 0.507 -83.1 178.4 NA NA NA
THR J:272 J:4290 72.0 0.514 -77.3 163.1 NA NA NA
THR K:272 K:5290 71.0 0.507 -92.7 165.2 NA NA NA
THR L:272 L:6290 63.0 0.45 -88.1 145.4 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:272 A:1290 64.0 0.457 -87.3 159.2 64.0 0.457 0.0 SO4
HOH
 4.713
2.816
 CA
OG1
 O2
O
THR B:272 B:2290 64.0 0.457 -87.1 158.2 64.0 0.457 0.0 SO4
HOH
 5.854
3.178
 CB
CB
 O1
O
THR C:272 C:3290 65.0 0.464 -85.1 157.4 65.0 0.464 0.0 SO4
HOH
 3.610
3.162
 CB
OG1
 O2
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:272 A:1290 71.0 0.507 -79.6 167.0 71.0 0.507 0.0 SO4
HOH
 3.198
2.764
 CA
OG1
 O2
O
THR B:272 B:2290 71.0 0.507 -86.7 170.4 71.0 0.507 0.0 SO4
HOH
 3.268
4.104
 CA
CB
 O4
O
THR C:272 C:3290 75.0 0.536 -77.5 165.0 75.0 0.536 0.0 SO4
HOH
 3.144
4.902
 CA
OG1
 O4
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:272 A:1290 64.0 0.457 -82.7 162.0 64.0 0.457 0.0 SO4
HOH
 3.496
6.538
 CA
OG1
 O2
O
THR B:272 B:2290 63.0 0.45 -83.5 163.4 63.0 0.45 0.0 SO4
HOH
 3.042
5.727
 CB
CG2
 O4
O
THR C:272 C:3290 65.0 0.464 -82.2 161.8 65.0 0.464 0.0 SO4
HOH
 3.014
5.590
 CA
C
 O4
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:272 A:1290 76.0 0.543 -81.5 164.4 68.0 0.486 0.057 B:P23141:0.057
 SO4
HOH
 3.305
2.828
 CA
OG1
 O2
O
THR B:272 B:2290 73.0 0.521 -79.5 166.5 73.0 0.521 0.0 SO4
HOH
 3.031
2.681
 CA
OG1
 O2
O
THR C:272 C:3290 68.0 0.486 -76.4 163.4 67.0 0.479 0.007 A:P23141:0.007
 SO4
HOH
 3.190
2.784
 CA
OG1
 O1
O
THR D:272 D:4290 75.0 0.536 -75.4 164.9 75.0 0.536 0.0 SO4
HOH
 3.151
2.759
 CA
OG1
 O2
O
THR E:272 E:5290 73.0 0.521 -83.0 166.4 69.0 0.493 0.028 D:P23141:0.029
 SO4
HOH
 3.449
2.638
 CA
OG1
 O3
O
THR F:272 F:6290 72.0 0.514 -77.9 166.1 72.0 0.514 0.0 SO4
HOH
 3.292
2.697
 CA
OG1
 O2
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:270 A:290 68.0 0.486 -83.3 162.1 68.0 0.486 0.0 SO4
HOH
 3.103
5.747
 CA
CG2
 O2
O
THR B:270 B:290 66.0 0.471 -84.6 167.6 66.0 0.471 0.0 SO4
HOH
 3.200
5.824
 CB
CA
 O4
O
THR C:270 C:290 70.0 0.5 -80.3 157.4 70.0 0.5 0.0 SO4
HOH
 3.129
2.862
 CA
OG1
 O4
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:270 A:290 72.0 0.514 -101.1 159.3 72.0 0.514 0.0 SO4
HOH
 3.307
4.334
 CA
CB
 O1
O
THR B:270 B:290 70.0 0.5 -92.0 162.1 70.0 0.5 0.0 SO4
HOH
 3.263
3.204
 CA
OG1
 O3
O
THR C:270 C:290 62.0 0.443 -77.4 157.4 59.0 0.421 0.022 A:P23141:0.021
 SO4
HOH
 3.147
4.762
 CA
CB
 O4
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:270 A:290 69.0 0.493 -84.2 159.9 69.0 0.493 0.0 SO4
HOH
 4.611
3.440
 CA
CA
 O1
O
THR B:270 B:290 69.0 0.493 -83.1 158.5 69.0 0.493 0.0 SO4
HOH
 3.649
6.273
 CG2
CA
 O4
O
THR C:270 C:290 68.0 0.486 -83.1 155.0 68.0 0.486 0.0 SO4
SO4
HOH
 3.133
8.362
4.522
 CA
N
CA
 O3
O1
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:270 A:290 57.0 0.407 -102.1 161.7 45.0 0.321 0.086 B:P23141:0.086
 SO4
HOH
 3.327
2.627
 CA
OG1
 O3
O
THR B:270 B:290 63.0 0.45 -93.9 178.4 60.0 0.429 0.021 C:P23141:0.021
 SO4
HOH
 3.173
2.830
 CA
OG1
 O3
O
THR C:270 C:290 69.0 0.493 -79.3 150.3 68.0 0.486 0.007 A:P23141:0.007
 SO4
HOH
 3.123
3.895
 CA
CB
 O2
O
THR D:270 D:290 56.0 0.4 -93.0 169.4 NA NA NA
THR E:270 E:290 59.0 0.421 -94.8 167.1 NA NA NA
THR F:270 F:290 74.0 0.529 -69.6 167.7 NA NA NA
THR G:270 G:290 74.0 0.529 -77.2 163.5 NA NA NA
THR H:270 H:290 53.0 0.379 -86.1 172.8 NA NA NA
THR I:270 I:290 59.0 0.421 -72.5 159.3 NA NA NA
THR J:270 J:290 73.0 0.521 -79.0 155.3 NA NA NA
THR K:270 K:290 65.0 0.464 -92.5 162.8 NA NA NA
THR L:270 L:290 65.0 0.464 -78.7 166.4 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:270 A:1290 69.0 0.493 -85.7 164.2 69.0 0.493 0.0 SO4
HOH
 3.690
3.617
 C
CB
 O3
O
THR B:270 B:2290 58.0 0.414 -73.9 165.7 53.0 0.379 0.035 C:Q9UK77:0.036
 SO4
HOH
 3.138
2.728
 CA
OG1
 O2
O
THR C:270 C:3290 60.0 0.429 -73.7 164.7 59.0 0.421 0.008 A:Q9UK77:0.007
 SO4
HOH
 2.930
3.931
 CA
CG2
 O2
O
THR D:270 D:4290 68.0 0.486 -90.5 165.4 NA NA NA
THR E:270 E:5290 73.0 0.521 -80.2 166.3 NA NA NA
THR F:270 F:6290 64.0 0.457 -70.5 161.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:270 A:1290 67.0 0.479 -93.2 169.4 67.0 0.479 0.0 SO4
HOH
 3.082
4.600
 CB
CG2
 O2
O
THR B:270 B:2290 72.0 0.514 -79.6 158.5 72.0 0.514 0.0 HOH
 3.041
 OG1
 O
THR C:270 C:3290 71.0 0.507 -77.0 157.5 68.0 0.486 0.021 A:Q9UK77:0.021
 SO4
HOH
 3.072
4.689
 CA
N
 O3
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 THR A:270 A:290 76.0 0.543 -79.3 164.9 76.0 0.543 0.0 SCN
HOH
 9.277
2.765
 N
OG1
 S
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 THR A:270 A:290 65.0 0.464 -74.5 156.4 65.0 0.464 0.0 PO4
HOH
 4.026
2.625
 N
OG1
 O2
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:270 A:290 62.0 0.443 -74.4 160.8 62.0 0.443 0.0 HOH
 2.755
 OG1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:269 A:290 64.0 0.457 -72.5 154.7 64.0 0.457 0.0 HOH
 6.738
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 THR A:267 A:1290 71.0 0.507 -82.2 157.7 62.0 0.443 0.064 B:P23141:0.064
THR B:267 B:2290 60.0 0.429 -82.1 157.4 58.0 0.414 0.015 C:P23141:0.014
 HOH
 6.579
 CA
 O
THR C:267 C:3290 62.0 0.443 -82.4 157.5 56.0 0.4 0.043 A:P23141:0.043
 HOH
 7.053
 CA
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 THR A:267 A:289 60.0 0.429 -97.5 153.7 60.0 0.429 0.0 HOH
 2.886
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 THR A:290 A:290 64.0 0.457 -72.3 167.3