Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55853521 . T A CCDS32450.1:NM_001025195.1:c.832Acc>Tcc_NP_001020366.1:p.278T>S Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 THR A:259 A:1277 109.0 0.779 S -50.8 -52.1 54.0 0.386 0.393 C:P23141:0.393
 HOH
 2.755
 OG1
 O
THR B:259 B:2277 108.0 0.771 S -53.6 -45.0 51.0 0.364 0.407 A:P23141:0.407
 SIA
HOH
 4.002
2.800
 O
OG1
 C11
O
THR C:259 C:3277 108.0 0.771 S -53.2 -44.5 46.0 0.329 0.442 B:P23141:0.443
 SIA
HOH
 5.588
3.463
 O
C
 N5
O
THR D:259 D:4277 110.0 0.786 S -51.2 -44.7 52.0 0.371 0.415 F:P23141:0.414
 HOH
 2.801
 OG1
 O
THR E:259 E:5277 104.0 0.743 S -51.9 -48.0 41.0 0.293 0.45 D:P23141:0.45
 SIA
HOH
 2.769
4.810
 O
O
 O9
O
THR F:259 F:6277 103.0 0.736 S -48.1 -48.5 50.0 0.357 0.379 E:P23141:0.379
 SIA
HOH
 4.883
2.883
 O
OG1
 O8
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:259 A:1277 107.0 0.764 S -40.8 -46.6 58.0 0.414 0.35 C:P23141:0.35
 HOH
 3.467
 OG1
 O
THR B:259 B:2277 96.0 0.686 S -44.0 -52.8 46.0 0.329 0.357 A:P23141:0.357
 SIA
HOH
 5.391
2.817
 O
OG1
 C9
O
THR C:259 C:3277 104.0 0.743 S -49.5 -44.4 36.0 0.257 0.486 B:P23141:0.486
 SIA
HOH
 4.135
2.714
 O
OG1
 C9
O
THR D:259 D:4277 105.0 0.75 S -42.2 -54.2 NA NA NA
THR E:259 E:5277 104.0 0.743 S -42.1 -49.0 NA NA NA
THR F:259 F:6277 105.0 0.75 S -50.6 -44.5 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:259 A:1277 102.0 0.729 S -33.8 -56.5 51.0 0.364 0.365 C:P23141:0.364
 HOH
 4.191
 N
 O
THR B:259 B:2277 101.0 0.721 S -64.9 -54.0 42.0 0.3 0.421 A:P23141:0.421
 NAG
HOH
 8.663
2.660
 O
OG1
 O7
O
THR C:259 C:3277 97.0 0.693 S -46.7 -42.4 40.0 0.286 0.407 B:P23141:0.407
 HOH
 2.687
 OG1
 O
THR D:259 D:4277 110.0 0.786 S -52.7 -51.7 55.0 0.393 0.393 F:P23141:0.393
 HOH
 2.937
 OG1
 O
THR E:259 E:5277 100.0 0.714 S -54.8 -51.8 43.0 0.307 0.407 D:P23141:0.407
 HOH
 4.876
 OG1
 O
THR F:259 F:6277 108.0 0.771 S -52.2 -47.2 51.0 0.364 0.407 E:P23141:0.407
 HOH
 4.843
 O
 O
THR G:259 G:1277 96.0 0.686 S -46.4 -53.2 NA NA NA
THR H:259 H:2277 92.0 0.657 S -60.4 -51.5 NA NA NA
THR I:259 I:3277 100.0 0.714 S -55.3 -52.4 NA NA NA
THR J:259 J:4277 107.0 0.764 S -48.9 -62.8 NA NA NA
THR K:259 K:5277 104.0 0.743 S -55.9 -54.8 NA NA NA
THR L:259 L:6277 102.0 0.729 S -54.0 -49.5 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:259 A:1277 106.0 0.757 S -49.0 -48.0 47.0 0.336 0.421 C:P23141:0.421
 SO4
SIA
HOH
 7.018
3.587
3.255
 OG1
O
O
 O1
O10
O
THR B:259 B:2277 104.0 0.743 S -48.8 -47.4 54.0 0.386 0.357 A:P23141:0.357
 SIA
HOH
 4.138
3.589
 O
OG1
 C11
O
THR C:259 C:3277 103.0 0.736 S -50.8 -48.4 42.0 0.3 0.436 B:P23141:0.436
 SIA
SO4
HOH
 4.340
6.408
3.410
 O
OG1
OG1
 C11
O2
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:259 A:1277 104.0 0.743 S -49.1 -43.8 36.0 0.257 0.486 C:P23141:0.486
 SIA
SO4
HOH
 3.434
9.956
2.531
 O
OG1
OG1
 C11
O2
O
THR B:259 B:2277 104.0 0.743 S -44.9 -44.4 41.0 0.293 0.45 A:P23141:0.45
 SIA
SO4
HOH
 3.362
9.789
2.766
 O
OG1
OG1
 C11
O3
O
THR C:259 C:3277 108.0 0.771 S -62.8 -36.8 47.0 0.336 0.435 B:P23141:0.436
 SIA
SO4
HOH
 4.971
9.512
2.859
 O
OG1
OG1
 C11
O3
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:259 A:1277 108.0 0.771 S -43.2 -43.8 45.0 0.321 0.45 C:P23141:0.45
 SIA
HOH
 5.000
4.012
 O
OG1
 C11
O
THR B:259 B:2277 103.0 0.736 S -44.4 -44.6 53.0 0.379 0.357 A:P23141:0.357
 SIA
SO4
HOH
 4.623
9.412
3.595
 O
OG1
O
 C11
O3
O
THR C:259 C:3277 107.0 0.764 S -44.1 -45.8 42.0 0.3 0.464 B:P23141:0.464
 SIA
SO4
HOH
 5.609
8.574
5.015
 O
OG1
O
 C11
O3
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:259 A:1277 102.0 0.729 S -49.3 -52.3 50.0 0.357 0.372 C:P23141:0.371
 SO4
HOH
 9.228
2.740
 OG1
OG1
 O4
O
THR B:259 B:2277 105.0 0.75 S -47.1 -52.1 49.0 0.35 0.4 A:P23141:0.4
 SO4
HOH
 9.528
2.899
 OG1
O
 O3
O
THR C:259 C:3277 107.0 0.764 S -50.0 -48.7 55.0 0.393 0.371 B:P23141:0.371
 SO4
HOH
 9.554
2.669
 OG1
OG1
 O4
O
THR D:259 D:4277 107.0 0.764 S -44.6 -51.5 54.0 0.386 0.378 E:P23141:0.379
 SO4
SIA
HOH
 9.610
4.107
2.661
 OG1
O
O
 O4
N5
O
THR E:259 E:5277 96.0 0.686 S -52.9 -49.2 43.0 0.307 0.379 F:P23141:0.379
 SO4
HOH
 9.619
2.943
 OG1
OG1
 O4
O
THR F:259 F:6277 106.0 0.757 S -51.4 -52.9 51.0 0.364 0.393 D:P23141:0.393
 SIA
SO4
HOH
 3.831
9.034
3.989
 O
OG1
O
 O1B
O3
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:257 A:277 101.0 0.721 S -39.2 -53.5 41.0 0.293 0.428 C:P23141:0.429
 SIA
SO4
HOH
 4.754
9.655
5.130
 O
OG1
O
 C11
O2
O
THR B:257 B:277 103.0 0.736 S -38.7 -43.1 47.0 0.336 0.4 A:P23141:0.4
 SIA
SO4
HOH
 4.120
8.409
3.363
 O
OG1
OG1
 C11
O1
O
THR C:257 C:277 102.0 0.729 S -46.6 -46.5 39.0 0.279 0.45 B:P23141:0.45
 SIA
SO4
HOH
 4.406
8.150
3.668
 O
OG1
OG1
 C11
O3
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:257 A:277 105.0 0.75 S -50.1 -50.4 37.0 0.264 0.486 C:P23141:0.486
 SIA
HOH
 4.670
3.093
 O
OG1
 N5
O
THR B:257 B:277 101.0 0.721 S -45.0 -54.2 53.0 0.379 0.342 A:P23141:0.343
 SIA
SO4
HOH
 3.376
8.960
3.970
 O
OG1
OG1
 C11
O4
O
THR C:257 C:277 103.0 0.736 S -48.6 -51.0 42.0 0.3 0.436 B:P23141:0.436
 SIA
SO4
HOH
 4.227
9.749
3.331
 O
OG1
OG1
 C11
O4
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:257 A:277 100.0 0.714 S -40.5 -51.3 46.0 0.329 0.385 C:P23141:0.386
 SIA
SO4
HOH
 4.366
9.450
5.701
 O
OG1
O
 O10
O2
O
THR B:257 B:277 99.0 0.707 S -37.7 -56.6 49.0 0.35 0.357 A:P23141:0.357
 SIA
HOH
 3.731
3.187
 O
OG1
 C11
O
THR C:257 C:277 102.0 0.729 S -37.1 -58.8 45.0 0.321 0.408 B:P23141:0.407
 SIA
SO4
HOH
 4.080
9.309
4.349
 O
OG1
OG1
 C10
O3
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:257 A:277 111.0 0.793 S -45.5 -54.6 53.0 0.379 0.414 C:P23141:0.414
 SIA
HOH
 5.012
3.634
 O
OG1
 O10
O
THR B:257 B:277 112.0 0.8 S -35.2 -62.2 51.0 0.364 0.436 A:P23141:0.436
 SIA
SO4
HOH
 3.666
9.654
3.968
 O
OG1
OG1
 O4
O2
O
THR C:257 C:277 119.0 0.85 S -49.5 -43.5 52.0 0.371 0.479 B:P23141:0.479
 SIA
HOH
 4.957
6.498
 O
O
 C11
O
THR D:257 D:277 103.0 0.736 S -50.9 -52.4 NA NA NA
THR E:257 E:277 111.0 0.793 S -39.6 -54.5 NA NA NA
THR F:257 F:277 109.0 0.779 S -78.4 -34.7 NA NA NA
THR G:257 G:277 112.0 0.8 S -58.4 -45.0 NA NA NA
THR H:257 H:277 114.0 0.814 S -50.3 -63.5 NA NA NA
THR I:257 I:277 98.0 0.7 S -51.5 -43.6 NA NA NA
THR J:257 J:277 118.0 0.843 S -54.4 -48.1 NA NA NA
THR K:257 K:277 116.0 0.829 S -41.9 -54.5 NA NA NA
THR L:257 L:277 112.0 0.8 S -40.9 -46.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:257 A:1277 103.0 0.736 S -50.3 -44.1 42.0 0.3 0.436 C:Q9UK77:0.436
 SO4
SIA
HOH
 9.078
4.199
3.246
 OG1
O
OG1
 O1
O10
O
THR B:257 B:2277 97.0 0.693 S -34.9 -53.5 47.0 0.336 0.357 A:Q9UK77:0.357
 SIA
SO4
HOH
 4.644
8.694
4.879
 O
OG1
O
 O1A
O4
O
THR C:257 C:3277 97.0 0.693 S -51.5 -47.2 39.0 0.279 0.414 B:Q9UK77:0.414
 SIA
SO4
HOH
 4.891
9.443
2.986
 O
OG1
OG1
 O8
O1
O
THR D:257 D:4277 101.0 0.721 S -43.2 -52.4 NA NA NA
THR E:257 E:5277 93.0 0.664 S -41.2 -48.2 NA NA NA
THR F:257 F:6277 95.0 0.679 S -48.6 -48.7 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:257 A:1277 106.0 0.757 S -51.1 -45.1 45.0 0.321 0.436 C:Q9UK77:0.436
 SO4
SIA
HOH
 9.530
5.421
3.161
 OG1
O
OG1
 O1
O7
O
THR B:257 B:2277 104.0 0.743 S -41.0 -49.9 51.0 0.364 0.379 A:Q9UK77:0.379
 SIA
SO4
HOH
 3.101
8.028
3.864
 O
OG1
N
 C11
O3
O
THR C:257 C:3277 106.0 0.757 S -47.8 -50.0 45.0 0.321 0.436 B:Q9UK77:0.436
 SIA
HOH
 4.650
2.907
 O
OG1
 C11
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 THR A:257 A:277 105.0 0.75 S -58.7 -41.1 49.0 0.35 0.4 A:P23141:0.4
 HOH
 3.839
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 THR A:257 A:277 107.0 0.764 S -56.0 -43.5 44.0 0.314 0.45 A:P23141-3:0.45
 HOH
 4.702
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:257 A:277 104.0 0.743 S -53.2 -46.3 104.0 0.743 0.0 HOH
 2.790
 OG1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:256 A:277 110.0 0.786 S -48.6 -51.3 110.0 0.786 0.0 IOD
HOH
 9.756
4.865
 OG1
O
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 THR A:254 A:1277 110.0 0.786 S -55.7 -39.9 38.0 0.271 0.515 C:P23141:0.514
THR B:254 B:2277 105.0 0.75 S -54.9 -40.2 36.0 0.257 0.493 A:P23141:0.493
 HOH
 8.226
 CG2
 O
THR C:254 C:3277 109.0 0.779 S -55.3 -40.6 68.0 0.486 0.293 B:P23141:0.293
 HOH
 8.781
 O
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 THR A:254 A:276 99.0 0.707 S -50.6 -41.5 99.0 0.707 0.0 HOH
 3.873
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 THR A:277 A:277 108.0 0.771 S -55.6 -44.1