Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55853536 . C A CCDS32450.1:NM_001025195.1:c.817Gct>Tct_NP_001020366.1:p.273A>S Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ALA A:254 A:1272 11.0 0.096 T -83.6 0.7 11.0 0.096 0.0 HOH
 3.987
 CA
 O
ALA B:254 B:2272 13.0 0.113 H -78.7 -6.2 13.0 0.113 0.0 HOH
 2.757
 O
 O
ALA C:254 C:3272 14.0 0.122 T -83.0 -1.9 14.0 0.122 0.0 HOH
 4.005
 CA
 O
ALA D:254 D:4272 16.0 0.139 T -86.0 -3.0 16.0 0.139 0.0 HOH
 2.858
 O
 O
ALA E:254 E:5272 15.0 0.13 H -78.1 -18.4 15.0 0.13 0.0 HOH
 4.356
 CA
 O
ALA F:254 F:6272 12.0 0.104 T -81.6 -6.4 12.0 0.104 0.0 HOH
 4.273
 CA
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:254 A:1272 12.0 0.104 T -87.9 -3.6 12.0 0.104 0.0 HOH
 4.114
 CA
 O
ALA B:254 B:2272 12.0 0.104 T -86.2 0.3 12.0 0.104 0.0 HOH
 5.190
 N
 O
ALA C:254 C:3272 10.0 0.087 T -85.5 -8.0 10.0 0.087 0.0 HOH
 2.812
 O
 O
ALA D:254 D:4272 12.0 0.104 T -79.8 -7.1 NA NA NA
ALA E:254 E:5272 10.0 0.087 T -77.8 -5.2 NA NA NA
ALA F:254 F:6272 16.0 0.139 T -92.7 -0.7 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:254 A:1272 12.0 0.104 T -75.2 -1.0 12.0 0.104 0.0 HOH
 6.020
 O
 O
ALA B:254 B:2272 12.0 0.104 H -72.2 -4.8 12.0 0.104 0.0 HOH
 7.782
 O
 O
ALA C:254 C:3272 11.0 0.096 T -85.6 13.5 11.0 0.096 0.0 HOH
 5.846
 O
 O
ALA D:254 D:4272 15.0 0.13 T -68.8 -0.5 15.0 0.13 0.0 HOH
 5.616
 O
 O
ALA E:254 E:5272 14.0 0.122 H -73.7 -12.4 14.0 0.122 0.0 HOH
 4.393
 O
 O
ALA F:254 F:6272 14.0 0.122 T -71.7 -3.4 14.0 0.122 0.0 HOH
 6.768
 N
 O
ALA G:254 G:1272 17.0 0.148 T -82.3 8.0 NA NA NA
ALA H:254 H:2272 14.0 0.122 H -76.8 -8.9 NA NA NA
ALA I:254 I:3272 16.0 0.139 T -107.8 4.8 NA NA NA
ALA J:254 J:4272 15.0 0.13 H -69.1 -14.7 NA NA NA
ALA K:254 K:5272 13.0 0.113 H -72.7 -1.7 NA NA NA
ALA L:254 L:6272 12.0 0.104 H -59.3 -14.5 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:254 A:1272 10.0 0.087 T -92.0 0.6 10.0 0.087 0.0 SO4
HOH
 9.687
5.569
 O
O
 O4
O
ALA B:254 B:2272 8.0 0.07 T -92.7 1.5 8.0 0.07 0.0 HOH
 6.106
 C
 O
ALA C:254 C:3272 10.0 0.087 T -91.4 0.5 10.0 0.087 0.0 SO4
HOH
 9.427
5.720
 O
C
 O1
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:254 A:1272 10.0 0.087 H -69.2 -18.0 10.0 0.087 0.0 HOH
 6.093
 O
 O
ALA B:254 B:2272 12.0 0.104 H -74.4 -7.7 12.0 0.104 0.0 HOH
 2.877
 O
 O
ALA C:254 C:3272 13.0 0.113 T -86.6 -4.3 13.0 0.113 0.0 HOH
 4.077
 CA
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:254 A:1272 10.0 0.087 T -82.3 -5.6 10.0 0.087 0.0 HOH
 6.610
 O
 O
ALA B:254 B:2272 11.0 0.096 T -84.0 -3.9 11.0 0.096 0.0
ALA C:254 C:3272 10.0 0.087 T -83.7 -4.2 10.0 0.087 0.0 HOH
 9.247
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:254 A:1272 14.0 0.122 T -81.8 -8.8 14.0 0.122 0.0 HOH
 2.901
 O
 O
ALA B:254 B:2272 16.0 0.139 H -84.7 -8.3 16.0 0.139 0.0 HOH
 2.775
 O
 O
ALA C:254 C:3272 13.0 0.113 T -79.6 -4.7 13.0 0.113 0.0 HOH
 2.789
 O
 O
ALA D:254 D:4272 15.0 0.13 T -77.1 -6.5 15.0 0.13 0.0 HOH
 2.838
 O
 O
ALA E:254 E:5272 10.0 0.087 T -82.4 -1.9 10.0 0.087 0.0 HOH
 4.112
 CA
 O
ALA F:254 F:6272 13.0 0.113 H -82.5 -10.8 13.0 0.113 0.0 HOH
 4.006
 CA
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:252 A:272 12.0 0.104 T -77.5 -1.9 12.0 0.104 0.0 HOH
 7.916
 O
 O
ALA B:252 B:272 11.0 0.096 T -83.3 0.3 11.0 0.096 0.0 HOH
 3.747
 CA
 O
ALA C:252 C:272 12.0 0.104 T -82.6 -6.6 12.0 0.104 0.0 HOH
 9.573
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:252 A:272 11.0 0.096 T -81.1 -5.1 11.0 0.096 0.0 HOH
 3.718
 O
 O
ALA B:252 B:272 15.0 0.13 H -82.2 -10.0 15.0 0.13 0.0 HOH
 3.431
 O
 O
ALA C:252 C:272 11.0 0.096 T -80.3 -7.2 11.0 0.096 0.0 HOH
 6.517
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:252 A:272 14.0 0.122 T -94.6 1.0 14.0 0.122 0.0 HOH
 5.056
 O
 O
ALA B:252 B:272 12.0 0.104 T -93.8 7.4 12.0 0.104 0.0 HOH
 3.386
 O
 O
ALA C:252 C:272 13.0 0.113 T -94.7 1.9 13.0 0.113 0.0 SO4
HOH
 7.972
2.711
 O
O
 O1
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:252 A:272 9.0 0.078 H -69.1 -8.9 9.0 0.078 0.0
ALA B:252 B:272 15.0 0.13 H -91.0 -16.1 15.0 0.13 0.0
ALA C:252 C:272 11.0 0.096 T -93.6 13.7 11.0 0.096 0.0 HOH
 4.574
 CA
 O
ALA D:252 D:272 9.0 0.078 H -80.4 -20.4 NA NA NA
ALA E:252 E:272 13.0 0.113 T -96.9 -18.3 NA NA NA
ALA F:252 F:272 8.0 0.07 T -83.1 -3.1 NA NA NA
ALA G:252 G:272 14.0 0.122 T -84.3 1.6 NA NA NA
ALA H:252 H:272 7.0 0.061 H -68.5 -28.0 NA NA NA
ALA I:252 I:272 17.0 0.148 H -83.6 -8.6 NA NA NA
ALA J:252 J:272 11.0 0.096 T -80.8 1.7 NA NA NA
ALA K:252 K:272 9.0 0.078 H -64.3 -29.4 NA NA NA
ALA L:252 L:272 15.0 0.13 H -82.3 -26.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:252 A:1272 12.0 0.104 H -89.7 -8.8 12.0 0.104 0.0 HOH
 5.138
 O
 O
ALA B:252 B:2272 16.0 0.139 H -94.0 -4.1 16.0 0.139 0.0 HOH
 5.491
 CA
 O
ALA C:252 C:3272 15.0 0.13 T -81.0 -3.8 15.0 0.13 0.0 HOH
 5.193
 N
 O
ALA D:252 D:4272 14.0 0.122 H -84.1 -12.1 NA NA NA
ALA E:252 E:5272 17.0 0.148 H -91.5 -5.8 NA NA NA
ALA F:252 F:6272 13.0 0.113 T -86.8 -4.1 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:252 A:1272 14.0 0.122 H -84.7 -14.3 14.0 0.122 0.0 HOH
 3.739
 O
 O
ALA B:252 B:2272 13.0 0.113 T -90.5 -3.1 13.0 0.113 0.0 HOH
 3.172
 O
 O
ALA C:252 C:3272 14.0 0.122 T -88.2 -3.9 14.0 0.122 0.0 HOH
 4.247
 CA
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ALA A:252 A:272 16.0 0.139 T -81.8 -2.3 16.0 0.139 0.0 HOH
 3.748
 CA
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ALA A:252 A:272 14.0 0.122 H -72.8 -13.5 14.0 0.122 0.0 HOH
 3.623
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:252 A:272 11.0 0.096 H -75.8 -8.5 11.0 0.096 0.0 HOH
 3.030
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:251 A:272 13.0 0.113 H -74.0 -14.1 13.0 0.113 0.0 IOD
HOH
 9.708
9.638
 O
N
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ALA A:249 A:1272 14.0 0.122 T -93.9 -3.3 14.0 0.122 0.0
ALA B:249 B:2272 14.0 0.122 T -94.4 -4.3 14.0 0.122 0.0
ALA C:249 C:3272 14.0 0.122 T -93.7 -2.9 14.0 0.122 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ALA A:249 A:271 18.0 0.157 H -90.9 -14.7 18.0 0.157 0.0 HOH
 4.454
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ALA A:272 A:272 8.0 0.07 T -77.5 -5.0