Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55853545 . C A CCDS32450.1:NM_001025195.1:c.808Gct>Tct_NP_001020366.1:p.270A>S Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ALA A:251 A:1269 0.0 0.0 H -62.8 -43.8 0.0 0.0 0.0 HOH
 6.734
 O
 O
ALA B:251 B:2269 0.0 0.0 H -64.4 -45.9 0.0 0.0 0.0 HOH
 4.836
 O
 O
ALA C:251 C:3269 0.0 0.0 H -61.4 -47.6 0.0 0.0 0.0 HOH
 5.002
 O
 O
ALA D:251 D:4269 0.0 0.0 H -65.3 -42.6 0.0 0.0 0.0 HOH
 5.040
 O
 O
ALA E:251 E:5269 0.0 0.0 H -57.5 -47.6 0.0 0.0 0.0 HOH
 4.954
 O
 O
ALA F:251 F:6269 0.0 0.0 H -62.4 -44.8 0.0 0.0 0.0 HOH
 5.163
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:251 A:1269 0.0 0.0 H -59.5 -45.6 0.0 0.0 0.0 HOH
 4.904
 O
 O
ALA B:251 B:2269 0.0 0.0 H -62.8 -45.3 0.0 0.0 0.0 HOH
 4.779
 O
 O
ALA C:251 C:3269 0.0 0.0 H -60.4 -41.1 0.0 0.0 0.0 HOH
 5.796
 O
 O
ALA D:251 D:4269 0.0 0.0 H -59.2 -44.1 NA NA NA
ALA E:251 E:5269 0.0 0.0 H -54.5 -43.0 NA NA NA
ALA F:251 F:6269 0.0 0.0 H -58.6 -46.5 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:251 A:1269 0.0 0.0 H -52.2 -59.7 0.0 0.0 0.0 HOH
 7.115
 O
 O
ALA B:251 B:2269 0.0 0.0 H -55.2 -46.4 0.0 0.0 0.0 HOH
 8.490
 N
 O
ALA C:251 C:3269 0.0 0.0 H -53.1 -56.1 0.0 0.0 0.0 HOH
 7.264
 O
 O
ALA D:251 D:4269 0.0 0.0 H -65.3 -47.2 0.0 0.0 0.0 HOH
 7.865
 O
 O
ALA E:251 E:5269 0.0 0.0 H -62.5 -45.6 0.0 0.0 0.0 HOH
 4.990
 O
 O
ALA F:251 F:6269 0.0 0.0 H -47.8 -56.5 0.0 0.0 0.0 HOH
 5.882
 C
 O
ALA G:251 G:1269 0.0 0.0 H -46.6 -57.9 NA NA NA
ALA H:251 H:2269 0.0 0.0 H -46.5 -50.9 NA NA NA
ALA I:251 I:3269 0.0 0.0 H -49.1 -55.9 NA NA NA
ALA J:251 J:4269 0.0 0.0 H -65.6 -41.6 NA NA NA
ALA K:251 K:5269 0.0 0.0 H -51.6 -56.1 NA NA NA
ALA L:251 L:6269 0.0 0.0 H -48.4 -55.9 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:251 A:1269 0.0 0.0 H -51.5 -51.3 0.0 0.0 0.0 SO4
HOH
 9.940
7.106
 O
O
 O4
O
ALA B:251 B:2269 0.0 0.0 H -50.0 -52.8 0.0 0.0 0.0 HOH
 4.844
 O
 O
ALA C:251 C:3269 0.0 0.0 H -49.8 -52.3 0.0 0.0 0.0 SO4
HOH
 9.141
4.965
 CB
O
 O4
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:251 A:1269 0.0 0.0 H -51.0 -52.2 0.0 0.0 0.0 HOH
 7.466
 O
 O
ALA B:251 B:2269 0.0 0.0 H -61.0 -47.1 0.0 0.0 0.0 HOH
 7.320
 O
 O
ALA C:251 C:3269 0.0 0.0 H -56.2 -44.7 0.0 0.0 0.0 HOH
 4.841
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:251 A:1269 0.0 0.0 H -51.6 -53.4 0.0 0.0 0.0 HOH
 7.143
 N
 O
ALA B:251 B:2269 0.0 0.0 H -52.1 -52.6 0.0 0.0 0.0 HOH
 7.673
 CB
 O
ALA C:251 C:3269 0.0 0.0 H -53.1 -51.4 0.0 0.0 0.0 HOH
 7.639
 CB
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:251 A:1269 0.0 0.0 H -56.7 -46.2 0.0 0.0 0.0 HOH
 4.983
 O
 O
ALA B:251 B:2269 0.0 0.0 H -63.2 -46.3 0.0 0.0 0.0 HOH
 2.696
 CB
 O
ALA C:251 C:3269 0.0 0.0 H -60.5 -47.5 0.0 0.0 0.0 HOH
 5.113
 O
 O
ALA D:251 D:4269 0.0 0.0 H -58.8 -45.4 0.0 0.0 0.0 HOH
 4.847
 O
 O
ALA E:251 E:5269 0.0 0.0 H -62.7 -45.4 0.0 0.0 0.0 HOH
 4.907
 O
 O
ALA F:251 F:6269 0.0 0.0 H -58.2 -47.5 0.0 0.0 0.0 HOH
 5.102
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:249 A:269 0.0 0.0 H -58.3 -46.4 0.0 0.0 0.0 HOH
 6.978
 O
 O
ALA B:249 B:269 0.0 0.0 H -60.3 -49.7 0.0 0.0 0.0 HOH
 6.943
 O
 O
ALA C:249 C:269 0.0 0.0 H -52.2 -45.8 0.0 0.0 0.0
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:249 A:269 0.0 0.0 H -58.4 -47.7 0.0 0.0 0.0 HOH
 7.076
 N
 O
ALA B:249 B:269 0.0 0.0 H -55.8 -50.8 0.0 0.0 0.0 HOH
 6.522
 O
 O
ALA C:249 C:269 0.0 0.0 H -52.0 -54.1 0.0 0.0 0.0 HOH
 8.106
 CB
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:249 A:269 0.0 0.0 H -54.9 -52.3 0.0 0.0 0.0 HOH
 7.612
 O
 O
ALA B:249 B:269 0.0 0.0 H -48.9 -55.4 0.0 0.0 0.0 HOH
 6.683
 O
 O
ALA C:249 C:269 0.0 0.0 H -55.3 -49.8 0.0 0.0 0.0 SO4
HOH
 9.291
4.475
 O
O
 O3
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:249 A:269 0.0 0.0 H -62.5 -60.2 0.0 0.0 0.0
ALA B:249 B:269 0.0 0.0 H -56.4 -57.7 0.0 0.0 0.0
ALA C:249 C:269 0.0 0.0 H -47.3 -48.9 0.0 0.0 0.0 HOH
 7.890
 O
 O
ALA D:249 D:269 0.0 0.0 H -54.3 -47.1 NA NA NA
ALA E:249 E:269 0.0 0.0 H -60.2 -18.4 NA NA NA
ALA F:249 F:269 0.0 0.0 H -63.9 -26.0 NA NA NA
ALA G:249 G:269 0.0 0.0 H -51.0 -48.7 NA NA NA
ALA H:249 H:269 0.0 0.0 H -57.7 -36.2 NA NA NA
ALA I:249 I:269 0.0 0.0 H -62.5 -55.5 NA NA NA
ALA J:249 J:269 0.0 0.0 H -59.0 -50.5 NA NA NA
ALA K:249 K:269 0.0 0.0 H -67.3 -47.7 NA NA NA
ALA L:249 L:269 0.0 0.0 H -55.8 -35.8 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:249 A:1269 0.0 0.0 H -55.4 -50.0 0.0 0.0 0.0 HOH
 6.893
 O
 O
ALA B:249 B:2269 0.0 0.0 H -55.5 -52.3 0.0 0.0 0.0 HOH
 8.749
 N
 O
ALA C:249 C:3269 0.0 0.0 H -54.2 -48.1 0.0 0.0 0.0 HOH
 6.948
 O
 O
ALA D:249 D:4269 0.0 0.0 H -57.9 -47.6 NA NA NA
ALA E:249 E:5269 0.0 0.0 H -58.9 -48.1 NA NA NA
ALA F:249 F:6269 0.0 0.0 H -54.3 -49.8 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:249 A:1269 0.0 0.0 H -59.3 -43.5 0.0 0.0 0.0 HOH
 6.406
 C
 O
ALA B:249 B:2269 0.0 0.0 H -53.5 -50.1 0.0 0.0 0.0 HOH
 4.579
 O
 O
ALA C:249 C:3269 0.0 0.0 H -58.6 -48.6 0.0 0.0 0.0 HOH
 7.070
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ALA A:249 A:269 0.0 0.0 H -62.9 -46.4 0.0 0.0 0.0 HOH
 5.189
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ALA A:249 A:269 0.0 0.0 H -57.7 -44.7 0.0 0.0 0.0 HOH
 7.223
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:249 A:269 0.0 0.0 H -59.5 -51.3 0.0 0.0 0.0 HOH
 5.068
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:248 A:269 0.0 0.0 H -62.6 -41.8 0.0 0.0 0.0 HOH
 8.060
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ALA A:246 A:1269 0.0 0.0 H -63.1 -41.6 0.0 0.0 0.0
ALA B:246 B:2269 0.0 0.0 H -63.2 -43.1 0.0 0.0 0.0
ALA C:246 C:3269 0.0 0.0 H -63.6 -42.5 0.0 0.0 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ALA A:246 A:268 0.0 0.0 H -63.4 -42.4 0.0 0.0 0.0 HOH
 4.771
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ALA A:269 A:269 0.0 0.0 H -59.8 -46.5