Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55854358 . G A CCDS32450.1:NM_001025195.1:c.727Cgg>Tgg_NP_001020366.1:p.243R>W Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ARG A:224 A:1242 44.0 0.196 E -151.0 151.8 44.0 0.196 0.0 HOH
 3.222
 NH2
 O
ARG B:224 B:2242 42.0 0.187 E -149.7 152.0 42.0 0.187 0.0 HOH
 3.974
 CD
 O
ARG C:224 C:3242 46.0 0.204 E -157.2 149.2 46.0 0.204 0.0 HOH
 2.922
 NH2
 O
ARG D:224 D:4242 41.0 0.182 E -152.8 142.7 41.0 0.182 0.0 HOH
 2.544
 NH2
 O
ARG E:224 E:5242 43.0 0.191 E -150.5 149.2 43.0 0.191 0.0 HOH
 3.470
 CZ
 O
ARG F:224 F:6242 46.0 0.204 E -155.9 149.7 46.0 0.204 0.0 HOH
 2.708
 NH1
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:224 A:1242 47.0 0.209 E -158.2 145.9 47.0 0.209 0.0 HOH
 2.799
 NH1
 O
ARG B:224 B:2242 43.0 0.191 E -150.5 156.2 43.0 0.191 0.0 HOH
 3.066
 NH1
 O
ARG C:224 C:3242 41.0 0.182 E -152.6 144.6 41.0 0.182 0.0 HOH
 3.742
 NH2
 O
ARG D:224 D:4242 43.0 0.191 E -155.6 154.2 NA NA NA
ARG E:224 E:5242 40.0 0.178 E -151.0 147.2 NA NA NA
ARG F:224 F:6242 46.0 0.204 E -156.7 146.9 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:224 A:1242 51.0 0.227 E -118.7 155.0 51.0 0.227 0.0 HOH
 3.357
 NH2
 O
ARG B:224 B:2242 40.0 0.178 E -141.2 155.3 40.0 0.178 0.0 HOH
 6.584
 N
 O
ARG C:224 C:3242 45.0 0.2 E -156.1 143.2 45.0 0.2 0.0 HOH
 3.547
 NH2
 O
ARG D:224 D:4242 47.0 0.209 E -151.3 160.8 47.0 0.209 0.0 HOH
 4.667
 CD
 O
ARG E:224 E:5242 47.0 0.209 E -152.5 137.4 47.0 0.209 0.0 HOH
 3.798
 NH1
 O
ARG F:224 F:6242 39.0 0.173 E -156.7 146.7 39.0 0.173 0.0 HOH
 3.754
 NH1
 O
ARG G:224 G:1242 48.0 0.213 E -150.7 153.8 NA NA NA
ARG H:224 H:2242 45.0 0.2 E -153.5 169.3 NA NA NA
ARG I:224 I:3242 44.0 0.196 E -149.9 149.2 NA NA NA
ARG J:224 J:4242 46.0 0.204 E -149.8 156.8 NA NA NA
ARG K:224 K:5242 48.0 0.213 E -151.7 149.7 NA NA NA
ARG L:224 L:6242 44.0 0.196 E -144.3 174.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:224 A:1242 44.0 0.196 E -159.9 145.9 44.0 0.196 0.0 HOH
 3.066
 NH2
 O
ARG B:224 B:2242 45.0 0.2 E -159.5 146.9 45.0 0.2 0.0 HOH
 4.721
 CD
 O
ARG C:224 C:3242 45.0 0.2 E -159.5 145.3 45.0 0.2 0.0 HOH
 2.390
 NH2
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:224 A:1242 42.0 0.187 E -153.2 147.3 42.0 0.187 0.0 HOH
 2.921
 NH1
 O
ARG B:224 B:2242 44.0 0.196 E -159.1 150.5 44.0 0.196 0.0 HOH
 3.934
 NH2
 O
ARG C:224 C:3242 46.0 0.204 E -151.9 138.2 46.0 0.204 0.0 HOH
 3.563
 NH2
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:224 A:1242 42.0 0.187 E -163.3 144.7 42.0 0.187 0.0 HOH
 4.535
 NE
 O
ARG B:224 B:2242 43.0 0.191 E -162.2 144.3 43.0 0.191 0.0 HOH
 2.662
 NH2
 O
ARG C:224 C:3242 42.0 0.187 E -162.7 143.7 42.0 0.187 0.0 HOH
 2.687
 NH2
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:224 A:1242 45.0 0.2 E -147.8 157.8 45.0 0.2 0.0 HOH
 3.707
 NH1
 O
ARG B:224 B:2242 42.0 0.187 E -156.6 148.0 42.0 0.187 0.0 HOH
 2.959
 NH2
 O
ARG C:224 C:3242 44.0 0.196 E -151.0 149.2 44.0 0.196 0.0 HOH
 3.715
 NH2
 O
ARG D:224 D:4242 43.0 0.191 E -152.3 155.2 43.0 0.191 0.0 HOH
 3.305
 NH1
 O
ARG E:224 E:5242 45.0 0.2 E -155.4 152.9 45.0 0.2 0.0 HOH
 3.065
 NH2
 O
ARG F:224 F:6242 41.0 0.182 E -154.2 157.0 41.0 0.182 0.0 HOH
 3.645
 NH1
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:222 A:242 47.0 0.209 E -158.9 138.2 47.0 0.209 0.0 HOH
 7.142
 N
 O
ARG B:222 B:242 49.0 0.218 E -160.5 139.5 49.0 0.218 0.0 HOH
 3.474
 NH1
 O
ARG C:222 C:242 48.0 0.213 E -158.8 135.0 48.0 0.213 0.0 HOH
 9.343
 N
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:222 A:242 38.0 0.169 E -162.3 161.3 38.0 0.169 0.0 HOH
 6.703
 N
 O
ARG B:222 B:242 46.0 0.204 E -152.5 152.1 46.0 0.204 0.0 HOH
 4.253
 CD
 O
ARG C:222 C:242 42.0 0.187 E -156.3 147.1 42.0 0.187 0.0 HOH
 6.411
 N
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:222 A:242 41.0 0.182 E -161.4 151.6 41.0 0.182 0.0 HOH
 2.746
 NH2
 O
ARG B:222 B:242 41.0 0.182 E -158.4 151.2 41.0 0.182 0.0 HOH
 6.759
 N
 O
ARG C:222 C:242 39.0 0.173 E -161.1 148.2 39.0 0.173 0.0 HOH
 3.064
 NH2
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:222 A:242 39.0 0.173 E -163.3 136.8 39.0 0.173 0.0 HOH
 8.006
 NH2
 O
ARG B:222 B:242 47.0 0.209 E -147.1 146.2 47.0 0.209 0.0 HOH
 3.060
 NH2
 O
ARG C:222 C:242 43.0 0.191 E -156.0 144.0 43.0 0.191 0.0 HOH
 5.619
 NH1
 O
ARG D:222 D:242 43.0 0.191 E -167.7 140.4 NA NA NA
ARG E:222 E:242 40.0 0.178 E -157.1 144.9 NA NA NA
ARG F:222 F:242 44.0 0.196 E -156.1 148.2 NA NA NA
ARG G:222 G:242 43.0 0.191 E -156.8 149.5 NA NA NA
ARG H:222 H:242 41.0 0.182 E -158.1 152.6 NA NA NA
ARG I:222 I:242 39.0 0.173 E -159.6 143.8 NA NA NA
ARG J:222 J:242 47.0 0.209 E -160.5 138.2 NA NA NA
ARG K:222 K:242 39.0 0.173 E -167.1 140.9 NA NA NA
ARG L:222 L:242 47.0 0.209 E -150.8 145.3 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:222 A:1242 42.0 0.187 E -159.3 147.0 42.0 0.187 0.0 HOH
 2.719
 NH2
 O
ARG B:222 B:2242 43.0 0.191 E -153.1 146.3 43.0 0.191 0.0 HOH
 4.414
 CD
 O
ARG C:222 C:3242 42.0 0.187 E -153.2 153.0 42.0 0.187 0.0 HOH
 3.097
 NH2
 O
ARG D:222 D:4242 41.0 0.182 E -157.2 147.0 NA NA NA
ARG E:222 E:5242 43.0 0.191 E -149.4 149.5 NA NA NA
ARG F:222 F:6242 43.0 0.191 E -158.8 148.5 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:222 A:1242 48.0 0.213 E -144.1 159.0 48.0 0.213 0.0 HOH
 2.756
 NH1
 O
ARG B:222 B:2242 47.0 0.209 E -141.2 149.0 47.0 0.209 0.0 HOH
 3.737
 NH2
 O
ARG C:222 C:3242 47.0 0.209 E -140.6 155.6 47.0 0.209 0.0 HOH
 3.214
 NH2
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ARG A:222 A:242 47.0 0.209 E -145.3 160.9 47.0 0.209 0.0 HOH
 4.040
 NH1
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ARG A:222 A:242 46.0 0.204 E -152.7 154.8 46.0 0.204 0.0 PO4
HOH
 6.667
2.942
 N
NH1
 O3
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:222 A:242 46.0 0.204 E -155.2 158.6 46.0 0.204 0.0 HOH
 2.785
 NH1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:221 A:242 44.0 0.196 E -149.1 159.4 44.0 0.196 0.0 HOH
 3.556
 CZ
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ARG A:219 A:1242 40.0 0.178 E -153.1 156.3 40.0 0.178 0.0 HOH
 4.989
 NH1
 O
ARG B:219 B:2242 39.0 0.173 E -153.8 157.2 39.0 0.173 0.0
ARG C:219 C:3242 38.0 0.169 E -153.2 156.4 38.0 0.169 0.0 HOH
 4.794
 NE
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ARG A:220 A:242 42.0 0.187 E -157.6 157.6 42.0 0.187 0.0 HOH
 2.722
 NH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ARG A:242 A:242 36.0 0.16 E -153.2 152.5
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ARG A:243 A:243 143.0 0.636 E -144.9 155.9