Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55855336 . G A CCDS32450.1:NM_001025195.1:c.637Cca>Tca_NP_001020366.1:p.213P>S Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 PRO A:194 A:1212 28.0 0.193 E -57.8 -13.6 28.0 0.193 0.0 HOH
 3.695
 CG
 O
PRO B:194 B:2212 32.0 0.221 E -63.7 -15.8 32.0 0.221 0.0 HOH
 3.888
 CG
 O
PRO C:194 C:3212 21.0 0.145 E -62.6 -13.9 21.0 0.145 0.0 HOH
 3.673
 CG
 O
PRO D:194 D:4212 26.0 0.179 E -63.7 -13.4 26.0 0.179 0.0 HOH
 3.768
 CG
 O
PRO E:194 E:5212 32.0 0.221 E -61.8 -20.5 32.0 0.221 0.0 HOH
 3.973
 CD
 O
PRO F:194 F:6212 19.0 0.131 E -58.2 -19.2 19.0 0.131 0.0 HOH
 3.152
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 PRO A:194 A:1212 38.0 0.262 E -55.3 -19.8 38.0 0.262 0.0 HOH
 4.060
 CG
 O
PRO B:194 B:2212 32.0 0.221 E -62.4 -15.7 32.0 0.221 0.0 HOH
 3.082
 O
 O
PRO C:194 C:3212 42.0 0.29 E -54.8 -22.4 42.0 0.29 0.0 HOH
 2.874
 O
 O
PRO D:194 D:4212 34.0 0.234 E -56.8 -2.5 NA NA NA
PRO E:194 E:5212 38.0 0.262 E -56.5 -14.2 NA NA NA
PRO F:194 F:6212 41.0 0.283 E -54.3 -21.0 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 PRO A:194 A:1212 27.0 0.186 E -65.1 7.3 27.0 0.186 0.0 HOH
 4.091
 CG
 O
PRO B:194 B:2212 28.0 0.193 E -55.1 -8.4 28.0 0.193 0.0 HOH
 3.765
 CG
 O
PRO C:194 C:3212 27.0 0.186 E -62.8 -22.7 27.0 0.186 0.0 HOH
 6.180
 C
 O
PRO D:194 D:4212 26.0 0.179 E -53.2 -11.8 26.0 0.179 0.0 HOH
 3.653
 CG
 O
PRO E:194 E:5212 30.0 0.207 E -72.0 2.6 30.0 0.207 0.0 HOH
 4.251
 CG
 O
PRO F:194 F:6212 29.0 0.2 E -60.6 -14.2 29.0 0.2 0.0 HOH
 3.238
 CG
 O
PRO G:194 G:1212 26.0 0.179 E -51.7 -23.5 NA NA NA
PRO H:194 H:2212 32.0 0.221 E -63.3 -14.4 NA NA NA
PRO I:194 I:3212 29.0 0.2 E -68.2 -30.2 NA NA NA
PRO J:194 J:4212 35.0 0.241 E -59.2 -17.3 NA NA NA
PRO K:194 K:5212 39.0 0.269 E -67.0 -4.9 NA NA NA
PRO L:194 L:6212 25.0 0.172 E -57.8 -9.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:194 A:1212 32.0 0.221 E -58.2 -14.7 32.0 0.221 0.0 HOH
 6.630
 O
 O
PRO B:194 B:2212 31.0 0.214 E -59.7 -14.0 31.0 0.214 0.0 HOH
 5.603
 O
 O
PRO C:194 C:3212 31.0 0.214 E -58.4 -14.3 31.0 0.214 0.0 HOH
 3.280
 CB
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:194 A:1212 37.0 0.255 E -51.6 -26.1 37.0 0.255 0.0 HOH
 4.547
 CG
 O
PRO B:194 B:2212 29.0 0.2 E -62.5 -14.1 29.0 0.2 0.0 HOH
 5.937
 O
 O
PRO C:194 C:3212 30.0 0.207 E -59.7 -28.1 30.0 0.207 0.0 HOH
 3.570
 CG
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:194 A:1212 38.0 0.262 E -51.2 -20.1 38.0 0.262 0.0 HOH
 4.289
 CB
 O
PRO B:194 B:2212 37.0 0.255 E -50.8 -21.0 37.0 0.255 0.0 HOH
 3.852
 CB
 O
PRO C:194 C:3212 37.0 0.255 E -51.2 -20.1 37.0 0.255 0.0 HOH
 3.453
 CB
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:194 A:1212 31.0 0.214 E -63.0 -16.6 31.0 0.214 0.0 HOH
 3.118
 O
 O
PRO B:194 B:2212 31.0 0.214 E -62.8 -18.1 31.0 0.214 0.0 HOH
 3.745
 O
 O
PRO C:194 C:3212 37.0 0.255 E -59.7 -10.6 37.0 0.255 0.0 HOH
 3.680
 CG
 O
PRO D:194 D:4212 37.0 0.255 E -62.5 -14.9 37.0 0.255 0.0 HOH
 3.311
 O
 O
PRO E:194 E:5212 34.0 0.234 E -63.1 -15.4 34.0 0.234 0.0 HOH
 2.657
 O
 O
PRO F:194 F:6212 31.0 0.214 E -59.9 -16.3 31.0 0.214 0.0 HOH
 3.793
 CB
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:192 A:212 33.0 0.228 E -55.2 -19.9 33.0 0.228 0.0 HOH
 4.188
 CB
 O
PRO B:192 B:212 31.0 0.214 E -52.4 -15.4 31.0 0.214 0.0 HOH
 9.323
 CD
 O
PRO C:192 C:212 32.0 0.221 E -56.0 -10.0 32.0 0.221 0.0 HOH
 3.059
 CG
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:192 A:212 48.0 0.331 E -56.8 -16.8 48.0 0.331 0.0 HOH
 3.262
 O
 O
PRO B:192 B:212 29.0 0.2 E -57.3 -11.3 29.0 0.2 0.0 HOH
 5.008
 O
 O
PRO C:192 C:212 34.0 0.234 E -58.4 -12.1 34.0 0.234 0.0 HOH
 3.587
 CD
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:192 A:212 30.0 0.207 E -55.1 -12.1 30.0 0.207 0.0 HOH
 3.729
 CG
 O
PRO B:192 B:212 30.0 0.207 E -59.2 -14.5 30.0 0.207 0.0 HOH
 3.641
 CG
 O
PRO C:192 C:212 30.0 0.207 E -59.1 -12.3 30.0 0.207 0.0 HOH
 4.505
 CG
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:192 A:212 42.0 0.29 E -58.8 10.4 42.0 0.29 0.0 HOH
 3.122
 O
 O
PRO B:192 B:212 36.0 0.248 E -58.8 -18.2 36.0 0.248 0.0 HOH
 5.521
 CG
 O
PRO C:192 C:212 27.0 0.186 E -57.6 -17.5 27.0 0.186 0.0 HOH
 3.620
 CB
 O
PRO D:192 D:212 41.0 0.283 E -63.3 -4.6 NA NA NA
PRO E:192 E:212 33.0 0.228 E -62.2 1.0 NA NA NA
PRO F:192 F:212 33.0 0.228 E -59.2 -14.4 NA NA NA
PRO G:192 G:212 28.0 0.193 E -61.9 -8.0 NA NA NA
PRO H:192 H:212 41.0 0.283 E -58.8 -10.0 NA NA NA
PRO I:192 I:212 35.0 0.241 E -59.3 1.0 NA NA NA
PRO J:192 J:212 34.0 0.234 E -47.6 -14.6 NA NA NA
PRO K:192 K:212 38.0 0.262 E -63.0 5.5 NA NA NA
PRO L:192 L:212 29.0 0.2 E -58.5 3.0 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 PRO A:192 A:1212 44.0 0.303 E -56.9 -18.8 44.0 0.303 0.0 HOH
 2.749
 O
 O
PRO B:192 B:2212 32.0 0.221 E -60.4 -14.2 32.0 0.221 0.0 HOH
 3.941
 CG
 O
PRO C:192 C:3212 31.0 0.214 E -61.5 -14.5 31.0 0.214 0.0 HOH
 3.866
 CD
 O
PRO D:192 D:4212 41.0 0.283 E -58.9 -15.5 NA NA NA
PRO E:192 E:5212 29.0 0.2 E -57.9 -19.6 NA NA NA
PRO F:192 F:6212 32.0 0.221 E -59.3 -21.4 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 PRO A:192 A:1212 33.0 0.228 E -57.5 -20.2 33.0 0.228 0.0 HOH
 3.933
 CB
 O
PRO B:192 B:2212 30.0 0.207 E -59.5 -18.5 30.0 0.207 0.0 HOH
 3.909
 CG
 O
PRO C:192 C:3212 24.0 0.166 E -59.9 -17.0 24.0 0.166 0.0 HOH
 3.896
 CB
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 PRO A:192 A:212 29.0 0.2 E -65.4 -16.7 29.0 0.2 0.0 HOH
 2.861
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 PRO A:192 A:212 31.0 0.214 E -64.8 -19.6 31.0 0.214 0.0 PO4
HOH
 8.756
3.798
 O
CG
 O1
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 PRO A:192 A:212 19.0 0.131 E -66.9 -17.4 19.0 0.131 0.0 HOH
 3.055
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 PRO A:191 A:212 25.0 0.172 E -76.4 -6.6 25.0 0.172 0.0 HOH
 3.064
 CG
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 PRO A:189 A:1212 30.0 0.207 E -64.3 -11.1 30.0 0.207 0.0 HOH
 5.983
 O
 O
PRO B:189 B:2212 45.0 0.31 E -63.6 -10.2 45.0 0.31 0.0
PRO C:189 C:3212 29.0 0.2 E -64.0 -10.6 29.0 0.2 0.0 HOH
 8.520
 C
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 PRO A:190 A:212 33.0 0.228 E -61.2 -11.2 33.0 0.228 0.0 HOH
 3.278
 CG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 PRO A:212 A:212 21.0 0.145 E -61.8 -24.1
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 PRO A:213 A:213 24.0 0.166 E -62.0 -24.9