Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55855361 . G A CCDS32450.1:NM_001025195.1:c.612gaC>gaT_NP_001020366.1:p.204D>D Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ASP A:185 A:1203 107.0 0.713 H -81.4 -18.8 107.0 0.713 0.0 HOH
 3.013
 OD1
 O
ASP B:185 B:2203 108.0 0.72 H -82.4 -13.3 108.0 0.72 0.0 HOH
 2.932
 O
 O
ASP C:185 C:3203 106.0 0.707 H -83.7 -22.9 106.0 0.707 0.0 HOH
 2.907
 O
 O
ASP D:185 D:4203 116.0 0.773 H -83.5 -21.8 116.0 0.773 0.0 HOH
 2.709
 OD2
 O
ASP E:185 E:5203 110.0 0.733 H -87.1 -21.2 110.0 0.733 0.0 HOH
 3.342
 OD2
 O
ASP F:185 F:6203 109.0 0.727 H -83.0 -19.0 109.0 0.727 0.0 HOH
 3.013
 OD2
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASP A:185 A:1203 116.0 0.773 H -86.4 -19.6 116.0 0.773 0.0 HOH
 2.807
 CG
 O
ASP B:185 B:2203 104.0 0.693 H -94.5 -16.0 104.0 0.693 0.0 HOH
 3.526
 O
 O
ASP C:185 C:3203 109.0 0.727 H -88.3 -13.5 109.0 0.727 0.0 HOH
 2.698
 OD1
 O
ASP D:185 D:4203 113.0 0.753 H -91.5 -15.7 NA NA NA
ASP E:185 E:5203 111.0 0.74 H -87.4 -18.0 NA NA NA
ASP F:185 F:6203 100.0 0.667 H -79.7 -17.9 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASP A:185 A:1203 112.0 0.747 H -87.0 -11.0 112.0 0.747 0.0 HOH
 3.194
 C
 O
ASP B:185 B:2203 104.0 0.693 H -94.3 -15.7 104.0 0.693 0.0 HOH
 3.301
 CG
 O
ASP C:185 C:3203 110.0 0.733 H -91.3 -6.1 110.0 0.733 0.0 HOH
 6.339
 O
 O
ASP D:185 D:4203 110.0 0.733 H -101.0 -6.8 110.0 0.733 0.0 HOH
 3.075
 O
 O
ASP E:185 E:5203 95.0 0.633 H -101.0 7.6 95.0 0.633 0.0 HOH
 3.023
 OD2
 O
ASP F:185 F:6203 107.0 0.713 H -106.1 -27.1 107.0 0.713 0.0 HOH
 3.883
 C
 O
ASP G:185 G:1203 109.0 0.727 H -86.3 0.5 NA NA NA
ASP H:185 H:2203 112.0 0.747 H -94.2 -11.0 NA NA NA
ASP I:185 I:3203 101.0 0.673 H -115.4 2.5 NA NA NA
ASP J:185 J:4203 103.0 0.687 H -102.3 -2.7 NA NA NA
ASP K:185 K:5203 98.0 0.653 H -72.9 -5.3 NA NA NA
ASP L:185 L:6203 104.0 0.693 H -104.1 -17.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASP A:185 A:1203 94.0 0.627 T -106.2 6.3 94.0 0.627 0.0 HOH
 2.698
 OD2
 O
ASP B:185 B:2203 91.0 0.607 H -105.5 5.6 91.0 0.607 0.0 HOH
 4.868
 OD1
 O
ASP C:185 C:3203 92.0 0.613 T -105.3 6.1 92.0 0.613 0.0 HOH
 3.536
 OD1
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASP A:185 A:1203 97.0 0.647 H -96.6 -22.5 97.0 0.647 0.0 HOH
 2.890
 OD2
 O
ASP B:185 B:2203 103.0 0.687 H -93.0 -18.6 103.0 0.687 0.0 HOH
 2.999
 OD1
 O
ASP C:185 C:3203 98.0 0.653 H -102.2 -12.0 98.0 0.653 0.0 HOH
 3.987
 C
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASP A:185 A:1203 108.0 0.72 H -80.4 -10.4 108.0 0.72 0.0 HOH
 2.745
 OD1
 O
ASP B:185 B:2203 108.0 0.72 H -78.8 -11.3 108.0 0.72 0.0 HOH
 3.654
 C
 O
ASP C:185 C:3203 103.0 0.687 H -78.8 -11.6 103.0 0.687 0.0 HOH
 4.098
 C
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASP A:185 A:1203 112.0 0.747 H -79.8 -18.9 112.0 0.747 0.0 HOH
 2.555
 OD2
 O
ASP B:185 B:2203 104.0 0.693 H -76.8 -16.2 104.0 0.693 0.0 HOH
 2.820
 O
 O
ASP C:185 C:3203 105.0 0.7 H -81.7 -18.8 105.0 0.7 0.0 HOH
 3.018
 O
 O
ASP D:185 D:4203 80.0 0.533 H -79.9 -21.2 80.0 0.533 0.0 HOH
 2.872
 O
 O
ASP E:185 E:5203 90.0 0.6 H -83.1 -17.5 90.0 0.6 0.0 HOH
 2.875
 O
 O
ASP F:185 F:6203 93.0 0.62 H -86.6 -9.9 93.0 0.62 0.0 HOH
 3.428
 OD2
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASP A:183 A:203 103.0 0.687 H -84.1 3.3 103.0 0.687 0.0 HOH
 3.296
 C
 O
ASP B:183 B:203 95.0 0.633 T -85.9 7.5 95.0 0.633 0.0 HOH
 6.769
 O
 O
ASP C:183 C:203 100.0 0.667 T -88.8 6.4 100.0 0.667 0.0 HOH
 4.487
 C
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASP A:183 A:203 105.0 0.7 H -95.0 -18.4 105.0 0.7 0.0 HOH
 2.854
 OD1
 O
ASP B:183 B:203 116.0 0.773 H -90.3 -14.7 116.0 0.773 0.0 HOH
 2.833
 O
 O
ASP C:183 C:203 113.0 0.753 H -87.3 -8.5 113.0 0.753 0.0 HOH
 3.025
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASP A:183 A:203 112.0 0.747 H -85.7 -9.3 112.0 0.747 0.0 HOH
 3.007
 O
 O
ASP B:183 B:203 110.0 0.733 H -89.9 -1.0 110.0 0.733 0.0 HOH
 3.939
 C
 O
ASP C:183 C:203 109.0 0.727 H -88.6 -8.8 109.0 0.727 0.0 HOH
 3.363
 C
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASP A:183 A:203 93.0 0.62 T -105.1 7.4 93.0 0.62 0.0 HOH
 3.130
 OD2
 O
ASP B:183 B:203 109.0 0.727 H -114.1 -3.5 109.0 0.727 0.0 HOH
 9.866
 O
 O
ASP C:183 C:203 97.0 0.647 H -96.3 0.0 97.0 0.647 0.0 HOH
 3.791
 C
 O
ASP D:183 D:203 96.0 0.64 T -100.9 14.8 NA NA NA
ASP E:183 E:203 111.0 0.74 H -102.4 -17.9 NA NA NA
ASP F:183 F:203 108.0 0.72 H -117.5 -2.5 NA NA NA
ASP G:183 G:203 109.0 0.727 H -119.6 -3.8 NA NA NA
ASP H:183 H:203 92.0 0.613 H -109.1 13.6 NA NA NA
ASP I:183 I:203 107.0 0.713 H -121.0 -27.9 NA NA NA
ASP J:183 J:203 106.0 0.707 T -107.4 2.7 NA NA NA
ASP K:183 K:203 97.0 0.647 T -113.4 14.8 NA NA NA
ASP L:183 L:203 96.0 0.64 T -104.0 49.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASP A:183 A:1203 102.0 0.68 H -87.7 -20.9 102.0 0.68 0.0 HOH
 2.572
 OD1
 O
ASP B:183 B:2203 117.0 0.78 H -88.4 -21.5 117.0 0.78 0.0 HOH
 2.826
 OD2
 O
ASP C:183 C:3203 115.0 0.767 H -91.9 -17.2 115.0 0.767 0.0 HOH
 3.492
 O
 O
ASP D:183 D:4203 102.0 0.68 H -85.5 -21.7 NA NA NA
ASP E:183 E:5203 112.0 0.747 H -85.9 -23.7 NA NA NA
ASP F:183 F:6203 114.0 0.76 H -87.5 -17.1 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASP A:183 A:1203 87.0 0.58 H -83.6 -20.4 87.0 0.58 0.0 HOH
 2.865
 OD1
 O
ASP B:183 B:2203 109.0 0.727 H -90.8 -25.6 109.0 0.727 0.0 HOH
 2.829
 OD2
 O
ASP C:183 C:3203 104.0 0.693 H -92.1 -13.1 104.0 0.693 0.0 HOH
 2.524
 OD2
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ASP A:183 A:203 98.0 0.653 H -78.8 -21.0 98.0 0.653 0.0 HOH
 2.805
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ASP A:183 A:203 117.0 0.78 H -78.4 -24.9 117.0 0.78 0.0 HOH
 3.472
 OD2
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASP A:183 A:203 114.0 0.76 H -79.5 -17.9 114.0 0.76 0.0 HOH
 2.713
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASP A:182 A:203 112.0 0.747 H -78.1 -13.2 112.0 0.747 0.0 HOH
 2.766
 OD2
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ASP A:180 A:1203 97.0 0.647 H -81.8 -20.3 97.0 0.647 0.0 HOH
 6.698
 N
 O
ASP B:180 B:2203 106.0 0.707 H -81.6 -20.1 106.0 0.707 0.0 HOH
 6.543
 O
 O
ASP C:180 C:3203 108.0 0.72 H -82.3 -20.5 108.0 0.72 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ASP A:181 A:203 108.0 0.72 H -82.3 0.6 108.0 0.72 0.0 HOH
 2.625
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ASP A:203 A:203 116.0 0.773 H -80.0 -25.5
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ASP A:204 A:204 106.0 0.707 H -78.5 -27.3