Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55855374 . C A CCDS32450.1:NM_001025195.1:c.599cGc>cTc_NP_001020366.1:p.200R>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ARG A:181 A:1199 122.0 0.542 H -73.3 -35.8 122.0 0.542 0.0 HOH
 2.699
 NH1
 O
ARG B:181 B:2199 120.0 0.533 H -72.4 -37.6 120.0 0.533 0.0 HOH
 2.528
 NH1
 O
ARG C:181 C:3199 122.0 0.542 H -71.8 -38.9 122.0 0.542 0.0 HOH
 2.601
 NH2
 O
ARG D:181 D:4199 123.0 0.547 H -70.7 -38.6 123.0 0.547 0.0 HOH
 2.914
 NE
 O
ARG E:181 E:5199 115.0 0.511 H -65.2 -42.9 115.0 0.511 0.0 HOH
 3.020
 CD
 O
ARG F:181 F:6199 120.0 0.533 H -67.5 -37.7 120.0 0.533 0.0 HOH
 2.678
 NH2
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:181 A:1199 119.0 0.529 H -71.3 -38.5 119.0 0.529 0.0 HOH
 3.329
 CB
 O
ARG B:181 B:2199 121.0 0.538 H -58.4 -45.7 121.0 0.538 0.0 HOH
 2.578
 NH1
 O
ARG C:181 C:3199 114.0 0.507 H -62.9 -45.7 114.0 0.507 0.0 HOH
 2.670
 NH2
 O
ARG D:181 D:4199 123.0 0.547 H -64.0 -42.3 NA NA NA
ARG E:181 E:5199 124.0 0.551 H -73.1 -35.8 NA NA NA
ARG F:181 F:6199 111.0 0.493 H -66.4 -37.0 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:181 A:1199 127.0 0.564 H -57.3 -45.0 127.0 0.564 0.0 HOH
 2.827
 NE
 O
ARG B:181 B:2199 119.0 0.529 H -79.8 -33.9 119.0 0.529 0.0 HOH
 3.755
 CB
 O
ARG C:181 C:3199 120.0 0.533 H -79.0 -33.6 120.0 0.533 0.0 HOH
 8.946
 O
 O
ARG D:181 D:4199 120.0 0.533 H -73.7 -42.2 120.0 0.533 0.0 HOH
 4.921
 N
 O
ARG E:181 E:5199 137.0 0.609 H -71.6 -39.6 137.0 0.609 0.0 HOH
 3.006
 NE
 O
ARG F:181 F:6199 118.0 0.524 H -63.7 -32.0 118.0 0.524 0.0 HOH
 3.423
 CB
 O
ARG G:181 G:1199 133.0 0.591 H -78.1 -20.2 NA NA NA
ARG H:181 H:2199 118.0 0.524 H -73.8 -40.4 NA NA NA
ARG I:181 I:3199 120.0 0.533 H -76.8 -24.1 NA NA NA
ARG J:181 J:4199 119.0 0.529 H -73.3 -36.5 NA NA NA
ARG K:181 K:5199 124.0 0.551 H -54.7 -33.3 NA NA NA
ARG L:181 L:6199 113.0 0.502 H -70.9 -26.5 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:181 A:1199 120.0 0.533 H -64.1 -39.6 120.0 0.533 0.0 HOH
 2.526
 NH2
 O
ARG B:181 B:2199 116.0 0.516 H -64.5 -38.9 116.0 0.516 0.0 HOH
 4.061
 NH2
 O
ARG C:181 C:3199 120.0 0.533 H -62.9 -40.7 120.0 0.533 0.0 HOH
 2.385
 NH2
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:181 A:1199 121.0 0.538 H -73.5 -38.8 121.0 0.538 0.0 HOH
 3.223
 CD
 O
ARG B:181 B:2199 133.0 0.591 H -68.4 -36.0 133.0 0.591 0.0 HOH
 2.883
 NH1
 O
ARG C:181 C:3199 119.0 0.529 H -69.0 -38.1 119.0 0.529 0.0 HOH
 2.752
 NE
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:181 A:1199 126.0 0.56 H -70.0 -36.6 126.0 0.56 0.0 HOH
 6.368
 O
 O
ARG B:181 B:2199 125.0 0.556 H -67.9 -37.9 125.0 0.556 0.0 HOH
 6.932
 O
 O
ARG C:181 C:3199 122.0 0.542 H -68.8 -37.6 122.0 0.542 0.0 HOH
 2.719
 NE
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:181 A:1199 130.0 0.578 H -64.8 -35.9 130.0 0.578 0.0 HOH
 2.769
 NH2
 O
ARG B:181 B:2199 119.0 0.529 H -68.0 -39.0 119.0 0.529 0.0 HOH
 2.391
 NH2
 O
ARG C:181 C:3199 113.0 0.502 H -66.4 -41.3 113.0 0.502 0.0 HOH
 2.586
 NH2
 O
ARG D:181 D:4199 121.0 0.538 H -69.3 -39.5 121.0 0.538 0.0 HOH
 2.944
 CD
 O
ARG E:181 E:5199 148.0 0.658 H -62.8 -38.4 148.0 0.658 0.0 HOH
 2.922
 NH1
 O
ARG F:181 F:6199 115.0 0.511 H -65.5 -41.1 115.0 0.511 0.0 HOH
 2.541
 NH1
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:179 A:199 118.0 0.524 H -63.9 -43.3 118.0 0.524 0.0 HOH
 3.404
 NH2
 O
ARG B:179 B:199 121.0 0.538 H -65.9 -36.9 121.0 0.538 0.0 HOH
 9.275
 O
 O
ARG C:179 C:199 118.0 0.524 H -68.3 -35.7 118.0 0.524 0.0 HOH
 2.962
 CD
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:179 A:199 119.0 0.529 H -73.0 -37.8 119.0 0.529 0.0 HOH
 4.299
 NH1
 O
ARG B:179 B:199 130.0 0.578 H -63.9 -39.7 130.0 0.578 0.0 HOH
 4.971
 N
 O
ARG C:179 C:199 121.0 0.538 H -64.0 -36.5 121.0 0.538 0.0 HOH
 2.422
 NH1
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:179 A:199 127.0 0.564 H -70.8 -34.6 127.0 0.564 0.0 HOH
 2.987
 NH2
 O
ARG B:179 B:199 125.0 0.556 H -64.7 -36.7 125.0 0.556 0.0 HOH
 4.892
 N
 O
ARG C:179 C:199 123.0 0.547 H -67.4 -36.1 123.0 0.547 0.0 HOH
 2.745
 NH1
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:179 A:199 133.0 0.591 H -63.2 -23.7 133.0 0.591 0.0 HOH
 2.725
 NH1
 O
ARG B:179 B:199 123.0 0.547 H -68.1 -43.4 123.0 0.547 0.0
ARG C:179 C:199 113.0 0.502 H -59.9 -53.3 113.0 0.502 0.0 HOH
 7.055
 O
 O
ARG D:179 D:199 129.0 0.573 H -66.5 -35.5 NA NA NA
ARG E:179 E:199 128.0 0.569 H -73.5 -40.8 NA NA NA
ARG F:179 F:199 109.0 0.484 H -72.7 -39.9 NA NA NA
ARG G:179 G:199 118.0 0.524 H -51.9 -36.6 NA NA NA
ARG H:179 H:199 123.0 0.547 H -56.9 -32.9 NA NA NA
ARG I:179 I:199 120.0 0.533 H -68.9 -35.5 NA NA NA
ARG J:179 J:199 110.0 0.489 H -62.1 -30.9 NA NA NA
ARG K:179 K:199 130.0 0.578 H -69.0 -19.4 NA NA NA
ARG L:179 L:199 128.0 0.569 H -70.3 -43.2 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:179 A:1199 116.0 0.516 H -65.9 -34.9 116.0 0.516 0.0 HOH
 3.182
 NH1
 O
ARG B:179 B:2199 119.0 0.529 H -68.9 -39.1 119.0 0.529 0.0 HOH
 3.135
 NE
 O
ARG C:179 C:3199 115.0 0.511 H -61.7 -35.5 115.0 0.511 0.0 HOH
 2.531
 NH1
 O
ARG D:179 D:4199 116.0 0.516 H -69.7 -37.2 NA NA NA
ARG E:179 E:5199 121.0 0.538 H -66.4 -38.8 NA NA NA
ARG F:179 F:6199 108.0 0.48 H -63.1 -38.1 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:179 A:1199 143.0 0.636 H -70.9 -33.1 143.0 0.636 0.0 HOH
 2.931
 NH1
 O
ARG B:179 B:2199 112.0 0.498 H -69.3 -35.6 112.0 0.498 0.0 HOH
 3.543
 NH1
 O
ARG C:179 C:3199 113.0 0.502 H -65.3 -43.0 113.0 0.502 0.0 HOH
 2.597
 NE
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ARG A:179 A:199 111.0 0.493 H -61.1 -44.4 111.0 0.493 0.0 HOH
 2.437
 NH2
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ARG A:179 A:199 109.0 0.484 H -61.4 -40.6 109.0 0.484 0.0 PO4
HOH
 9.086
2.912
 NH1
NH1
 O2
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:179 A:199 110.0 0.489 H -64.1 -41.3 110.0 0.489 0.0 HOH
 2.728
 NH1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:178 A:199 121.0 0.538 H -63.8 -38.5 121.0 0.538 0.0 IOD
HOH
 8.173
2.863
 NH2
NE
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ARG A:176 A:1199 161.0 0.716 H -83.1 -21.7 161.0 0.716 0.0 HOH
 4.423
 N
 O
ARG B:176 B:2199 142.0 0.631 H -83.9 -21.9 142.0 0.631 0.0 HOH
 7.730
 C
 O
ARG C:176 C:3199 111.0 0.493 H -83.1 -22.6 111.0 0.493 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ARG A:177 A:199 114.0 0.507 H -67.3 -40.2 114.0 0.507 0.0 HOH
 2.603
 NH1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ARG A:199 A:199 118.0 0.524 H -62.0 -44.6
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 HIS A:200 A:200 91.0 0.467 H -58.8 -46.6