Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 55855381 | . | C | A | CCDS32450.1:NM_001025195.1:c.592Gcc>Tcc_NP_001020366.1:p.198A>S | Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1mx1 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-22 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -71.1 | -36.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.798 |
N |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -69.3 | -40.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.869 |
N |
O |
|||||||||
| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -67.0 | -37.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.791 |
N |
O |
|||||||||
| ALA | D:179 | D:4197 | 0.0 | 0.0 | H | -64.5 | -37.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.697 |
N |
O |
|||||||||
| ALA | E:179 | E:5197 | 0.0 | 0.0 | H | -68.3 | -41.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.683 |
N |
O |
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| ALA | F:179 | F:6197 | 0.0 | 0.0 | H | -67.2 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.819 |
N |
O |
|||||||||
| 1mx5 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -66.2 | -33.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.853 |
N |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -63.0 | -42.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.787 |
N |
O |
|||||||||
| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -70.4 | -36.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.790 |
N |
O |
|||||||||
| ALA | D:179 | D:4197 | 0.0 | 0.0 | H | -57.2 | -44.2 | NA | NA | NA | |||||||||||||
| ALA | E:179 | E:5197 | 0.0 | 0.0 | H | -66.7 | -32.7 | NA | NA | NA | |||||||||||||
| ALA | F:179 | F:6197 | 0.0 | 0.0 | H | -72.3 | -46.0 | NA | NA | NA | |||||||||||||
| 1mx9 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -64.9 | -43.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.594 |
O |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -61.0 | -46.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.957 |
N |
O |
|||||||||
| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -67.6 | -44.9 | 0.0 | 0.0 | 0.0 |
HOH |
9.401 |
CB |
O |
|||||||||
| ALA | D:179 | D:4197 | 1.0 | 0.009 | H | -70.0 | -39.3 | 1.0 | 0.009 | 0.0 |
HOH |
5.671 |
O |
O |
|||||||||
| ALA | E:179 | E:5197 | 0.0 | 0.0 | H | -69.4 | -38.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.599 |
O |
O |
|||||||||
| ALA | F:179 | F:6197 | 0.0 | 0.0 | H | -57.6 | -52.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.966 |
N |
O |
|||||||||
| ALA | G:179 | G:1197 | 0.0 | 0.0 | H | -58.6 | -39.4 | NA | NA | NA | |||||||||||||
| ALA | H:179 | H:2197 | 0.0 | 0.0 | H | -69.6 | -49.7 | NA | NA | NA | |||||||||||||
| ALA | I:179 | I:3197 | 0.0 | 0.0 | H | -52.5 | -52.7 | NA | NA | NA | |||||||||||||
| ALA | J:179 | J:4197 | 0.0 | 0.0 | H | -62.5 | -42.0 | NA | NA | NA | |||||||||||||
| ALA | K:179 | K:5197 | 0.0 | 0.0 | H | -55.8 | -47.3 | NA | NA | NA | |||||||||||||
| ALA | L:179 | L:6197 | 0.0 | 0.0 | H | -59.0 | -48.3 | NA | NA | NA | |||||||||||||
| 2dqy | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -64.4 | -36.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.745 |
O |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -63.8 | -35.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.212 |
CB |
O |
|||||||||
| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -64.7 | -33.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.681 |
N |
O |
|||||||||
| 2dqz | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -73.3 | -38.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.080 |
N |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -66.5 | -33.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.094 |
N |
O |
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| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -60.2 | -31.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.394 |
N |
O |
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| 2dr0 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -58.0 | -38.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.218 |
CB |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -57.5 | -39.6 | 0.0 | 0.0 | 0.0 |
HOH |
9.353 |
CB |
O |
|||||||||
| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -58.1 | -38.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.221 |
N |
O |
|||||||||
| 2h7c | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:179 | A:1197 | 0.0 | 0.0 | H | -62.9 | -37.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.764 |
N |
O |
||
| ALA | B:179 | B:2197 | 0.0 | 0.0 | H | -67.7 | -40.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.762 |
N |
O |
|||||||||
| ALA | C:179 | C:3197 | 0.0 | 0.0 | H | -67.7 | -36.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.871 |
N |
O |
|||||||||
| ALA | D:179 | D:4197 | 0.0 | 0.0 | H | -63.4 | -41.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.813 |
N |
O |
|||||||||
| ALA | E:179 | E:5197 | 0.0 | 0.0 | H | -64.0 | -42.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.762 |
N |
O |
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| ALA | F:179 | F:6197 | 0.0 | 0.0 | H | -65.9 | -41.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.870 |
N |
O |
|||||||||
| 1ya4 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -56.3 | -43.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.674 |
O |
O |
||
| ALA | B:177 | B:197 | 0.0 | 0.0 | H | -59.9 | -45.1 | 0.0 | 0.0 | 0.0 |
HOH |
9.187 |
CB |
O |
|||||||||
| ALA | C:177 | C:197 | 0.0 | 0.0 | H | -55.0 | -34.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.833 |
N |
O |
|||||||||
| 1ya8 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -69.7 | -28.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.384 |
N |
O |
||
| ALA | B:177 | B:197 | 0.0 | 0.0 | H | -66.9 | -38.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.847 |
O |
O |
|||||||||
| ALA | C:177 | C:197 | 0.0 | 0.0 | H | -59.6 | -39.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.275 |
O |
O |
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| 1yah | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -68.3 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.080 |
N |
O |
||
| ALA | B:177 | B:197 | 0.0 | 0.0 | H | -67.2 | -41.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.055 |
N |
O |
|||||||||
| ALA | C:177 | C:197 | 0.0 | 0.0 | H | -67.0 | -44.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.543 |
O |
O |
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| 1yaj | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -77.4 | -43.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.318 |
O |
O |
||
| ALA | B:177 | B:197 | 0.0 | 0.0 | H | -61.8 | -58.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.039 |
CB |
O |
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| ALA | C:177 | C:197 | 0.0 | 0.0 | H | -73.1 | -44.0 | 0.0 | 0.0 | 0.0 |
HOH |
9.456 |
CB |
O |
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| ALA | D:177 | D:197 | 0.0 | 0.0 | H | -76.3 | -46.8 | NA | NA | NA | |||||||||||||
| ALA | E:177 | E:197 | 0.0 | 0.0 | H | -61.0 | -48.9 | NA | NA | NA | |||||||||||||
| ALA | F:177 | F:197 | 0.0 | 0.0 | H | -60.6 | -46.0 | NA | NA | NA | |||||||||||||
| ALA | G:177 | G:197 | 0.0 | 0.0 | H | -54.9 | -42.3 | NA | NA | NA | |||||||||||||
| ALA | H:177 | H:197 | 1.0 | 0.009 | H | -60.1 | -39.7 | NA | NA | NA | |||||||||||||
| ALA | I:177 | I:197 | 0.0 | 0.0 | H | -51.5 | -40.8 | NA | NA | NA | |||||||||||||
| ALA | J:177 | J:197 | 0.0 | 0.0 | H | -66.7 | -48.9 | NA | NA | NA | |||||||||||||
| ALA | K:177 | K:197 | 1.0 | 0.009 | H | -74.7 | -34.2 | NA | NA | NA | |||||||||||||
| ALA | L:177 | L:197 | 0.0 | 0.0 | H | -68.9 | -48.7 | NA | NA | NA | |||||||||||||
| 2hrq | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ALA | A:177 | A:1197 | 0.0 | 0.0 | H | -66.7 | -42.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.817 |
N |
O |
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| ALA | B:177 | B:2197 | 0.0 | 0.0 | H | -70.7 | -30.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.735 |
N |
O |
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| ALA | C:177 | C:3197 | 0.0 | 0.0 | H | -62.3 | -42.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.855 |
N |
O |
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| ALA | D:177 | D:4197 | 0.0 | 0.0 | H | -69.0 | -39.6 | NA | NA | NA | |||||||||||||
| ALA | E:177 | E:5197 | 0.0 | 0.0 | H | -69.3 | -31.7 | NA | NA | NA | |||||||||||||
| ALA | F:177 | F:6197 | 0.0 | 0.0 | H | -66.0 | -41.9 | NA | NA | NA | |||||||||||||
| 2hrr | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ALA | A:177 | A:1197 | 0.0 | 0.0 | H | -68.1 | -38.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.906 |
N |
O |
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| ALA | B:177 | B:2197 | 0.0 | 0.0 | H | -69.1 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.733 |
N |
O |
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| ALA | C:177 | C:3197 | 0.0 | 0.0 | H | -73.3 | -43.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.854 |
N |
O |
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| 4ab1 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2012-03-07 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -64.5 | -34.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.800 |
N |
O |
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| 5a7f | 1 | P23141-3 | 99.81 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -61.7 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.830 |
N |
O |
||
| 5a7g | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:177 | A:197 | 0.0 | 0.0 | H | -65.0 | -42.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.861 |
N |
O |
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| 5a7h | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:176 | A:197 | 0.0 | 0.0 | H | -64.3 | -35.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.797 |
N |
O |
||
| 3k9b | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2010-01-19 | ALA | A:174 | A:1197 | 0.0 | 0.0 | H | -70.5 | -40.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.174 |
O |
O |
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| ALA | B:174 | B:2197 | 0.0 | 0.0 | H | -68.4 | -40.7 | 0.0 | 0.0 | 0.0 |
HOH |
8.149 |
N |
O |
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| ALA | C:174 | C:3197 | 0.0 | 0.0 | H | -68.5 | -41.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 1k4y | 1 | 3219695 | 82.06 | 0.0 |
X-RAY |
2002-05-01 | ALA | A:175 | A:197 | 0.0 | 0.0 | H | -69.2 | -38.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.124 |
N |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p23141-f1 | 1 | P23141 | 99.82 | 0.0 | ALA | A:197 | A:197 | 0.0 | 0.0 | H | -61.7 | -40.3 | |
| af-q9uky3-f1 | 1 | Q9UKY3 | 93.63 | 3e-170 | ALA | A:198 | A:198 | 0.0 | 0.0 | H | -63.4 | -38.2 | |