Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 55855402 | . | C | A | CCDS32450.1:NM_001025195.1:c.571Ggt>Tgt_NP_001020366.1:p.191G>C | Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1mx1 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-22 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -62.5 | -38.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.912 |
N |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -65.5 | -34.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.912 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -64.3 | -34.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.872 |
N |
O |
|||||||||
| GLY | D:172 | D:4190 | 0.0 | 0.0 | H | -61.4 | -40.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.812 |
N |
O |
|||||||||
| GLY | E:172 | E:5190 | 0.0 | 0.0 | H | -64.6 | -40.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.764 |
N |
O |
|||||||||
| GLY | F:172 | F:6190 | 0.0 | 0.0 | H | -56.2 | -45.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.948 |
N |
O |
|||||||||
| 1mx5 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -59.6 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.606 |
N |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -60.1 | -40.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.596 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -62.6 | -33.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.731 |
N |
O |
|||||||||
| GLY | D:172 | D:4190 | 0.0 | 0.0 | H | -62.1 | -44.2 | NA | NA | NA | |||||||||||||
| GLY | E:172 | E:5190 | 0.0 | 0.0 | H | -61.3 | -36.5 | NA | NA | NA | |||||||||||||
| GLY | F:172 | F:6190 | 0.0 | 0.0 | H | -54.3 | -38.3 | NA | NA | NA | |||||||||||||
| 1mx9 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -52.9 | -46.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.173 |
O |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -58.0 | -40.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.736 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -62.5 | -47.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.362 |
N |
O |
|||||||||
| GLY | D:172 | D:4190 | 0.0 | 0.0 | H | -54.5 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.797 |
N |
O |
|||||||||
| GLY | E:172 | E:5190 | 0.0 | 0.0 | H | -64.6 | -47.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.527 |
N |
O |
|||||||||
| GLY | F:172 | F:6190 | 0.0 | 0.0 | H | -61.6 | -40.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.739 |
N |
O |
|||||||||
| GLY | G:172 | G:1190 | 0.0 | 0.0 | H | -51.8 | -47.5 | NA | NA | NA | |||||||||||||
| GLY | H:172 | H:2190 | 0.0 | 0.0 | H | -61.0 | -47.6 | NA | NA | NA | |||||||||||||
| GLY | I:172 | I:3190 | 0.0 | 0.0 | H | -56.2 | -48.2 | NA | NA | NA | |||||||||||||
| GLY | J:172 | J:4190 | 0.0 | 0.0 | H | -70.6 | -38.8 | NA | NA | NA | |||||||||||||
| GLY | K:172 | K:5190 | 0.0 | 0.0 | H | -59.5 | -49.2 | NA | NA | NA | |||||||||||||
| GLY | L:172 | L:6190 | 0.0 | 0.0 | H | -65.0 | -40.9 | NA | NA | NA | |||||||||||||
| 2dqy | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -56.8 | -45.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.756 |
N |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -56.3 | -45.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.977 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -54.6 | -47.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.719 |
N |
O |
|||||||||
| 2dqz | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -61.4 | -35.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.424 |
N |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -62.7 | -40.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.015 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -57.2 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.801 |
N |
O |
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| 2dr0 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -54.7 | -50.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.746 |
N |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -54.3 | -49.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.552 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -54.8 | -48.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.795 |
N |
O |
|||||||||
| 2h7c | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | GLY | A:172 | A:1190 | 0.0 | 0.0 | H | -66.5 | -32.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.855 |
N |
O |
||
| GLY | B:172 | B:2190 | 0.0 | 0.0 | H | -61.8 | -37.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.898 |
N |
O |
|||||||||
| GLY | C:172 | C:3190 | 0.0 | 0.0 | H | -63.9 | -36.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.845 |
N |
O |
|||||||||
| GLY | D:172 | D:4190 | 0.0 | 0.0 | H | -69.7 | -34.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.767 |
N |
O |
|||||||||
| GLY | E:172 | E:5190 | 0.0 | 0.0 | H | -61.8 | -40.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.737 |
N |
O |
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| GLY | F:172 | F:6190 | 0.0 | 0.0 | H | -64.2 | -39.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.837 |
N |
O |
|||||||||
| 1ya4 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -51.1 | -49.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.401 |
N |
O |
||
| GLY | B:170 | B:190 | 0.0 | 0.0 | H | -53.5 | -43.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.084 |
N |
O |
|||||||||
| GLY | C:170 | C:190 | 0.0 | 0.0 | H | -54.4 | -51.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.783 |
N |
O |
|||||||||
| 1ya8 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -59.6 | -46.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.534 |
N |
O |
||
| GLY | B:170 | B:190 | 0.0 | 0.0 | H | -55.5 | -48.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.760 |
N |
O |
|||||||||
| GLY | C:170 | C:190 | 0.0 | 0.0 | H | -58.3 | -38.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.002 |
N |
O |
|||||||||
| 1yah | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -47.1 | -50.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.652 |
N |
O |
||
| GLY | B:170 | B:190 | 0.0 | 0.0 | H | -53.0 | -46.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.740 |
N |
O |
|||||||||
| GLY | C:170 | C:190 | 0.0 | 0.0 | H | -52.2 | -45.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.587 |
N |
O |
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| 1yaj | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -68.3 | -41.4 | 0.0 | 0.0 | 0.0 |
HOH |
8.475 |
O |
O |
||
| GLY | B:170 | B:190 | 0.0 | 0.0 | H | -53.6 | -55.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.528 |
N |
O |
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| GLY | C:170 | C:190 | 0.0 | 0.0 | H | -62.6 | -37.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.252 |
N |
O |
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| GLY | D:170 | D:190 | 0.0 | 0.0 | H | -55.6 | -47.6 | NA | NA | NA | |||||||||||||
| GLY | E:170 | E:190 | 0.0 | 0.0 | H | -56.1 | -43.5 | NA | NA | NA | |||||||||||||
| GLY | F:170 | F:190 | 0.0 | 0.0 | H | -54.4 | -34.0 | NA | NA | NA | |||||||||||||
| GLY | G:170 | G:190 | 0.0 | 0.0 | H | -54.3 | -37.4 | NA | NA | NA | |||||||||||||
| GLY | H:170 | H:190 | 0.0 | 0.0 | H | -60.5 | -57.4 | NA | NA | NA | |||||||||||||
| GLY | I:170 | I:190 | 0.0 | 0.0 | H | -47.7 | -45.6 | NA | NA | NA | |||||||||||||
| GLY | J:170 | J:190 | 0.0 | 0.0 | H | -60.6 | -41.7 | NA | NA | NA | |||||||||||||
| GLY | K:170 | K:190 | 0.0 | 0.0 | H | -70.9 | -54.9 | NA | NA | NA | |||||||||||||
| GLY | L:170 | L:190 | 0.0 | 0.0 | H | -55.7 | -45.3 | NA | NA | NA | |||||||||||||
| 2hrq | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | GLY | A:170 | A:1190 | 0.0 | 0.0 | H | -64.2 | -36.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.707 |
N |
O |
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| GLY | B:170 | B:2190 | 0.0 | 0.0 | H | -61.5 | -34.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.908 |
N |
O |
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| GLY | C:170 | C:3190 | 0.0 | 0.0 | H | -57.2 | -36.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.790 |
N |
O |
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| GLY | D:170 | D:4190 | 0.0 | 0.0 | H | -62.9 | -33.9 | NA | NA | NA | |||||||||||||
| GLY | E:170 | E:5190 | 0.0 | 0.0 | H | -55.8 | -42.1 | NA | NA | NA | |||||||||||||
| GLY | F:170 | F:6190 | 0.0 | 0.0 | H | -60.8 | -36.8 | NA | NA | NA | |||||||||||||
| 2hrr | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | GLY | A:170 | A:1190 | 0.0 | 0.0 | H | -58.9 | -37.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.916 |
N |
O |
||
| GLY | B:170 | B:2190 | 0.0 | 0.0 | H | -61.6 | -40.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.074 |
N |
O |
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| GLY | C:170 | C:3190 | 0.0 | 0.0 | H | -60.9 | -38.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.775 |
N |
O |
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| 4ab1 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2012-03-07 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -70.7 | -35.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.808 |
N |
O |
||
| 5a7f | 1 | P23141-3 | 99.81 | 0.0 |
X-RAY |
2016-01-13 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -57.7 | -39.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.891 |
N |
O |
||
| 5a7g | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | GLY | A:170 | A:190 | 0.0 | 0.0 | H | -62.9 | -39.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.876 |
N |
O |
||
| 5a7h | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | GLY | A:169 | A:190 | 0.0 | 0.0 | H | -58.9 | -37.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.807 |
N |
O |
||
| 3k9b | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2010-01-19 | GLY | A:167 | A:1190 | 0.0 | 0.0 | H | -63.4 | -41.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.218 |
N |
O |
||
| GLY | B:167 | B:2190 | 0.0 | 0.0 | H | -62.0 | -41.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
| GLY | C:167 | C:3190 | 0.0 | 0.0 | H | -61.5 | -41.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.578 |
N |
O |
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| 1k4y | 1 | 3219695 | 82.06 | 0.0 |
X-RAY |
2002-05-01 | GLY | A:168 | A:190 | 0.0 | 0.0 | H | -53.1 | -42.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.716 |
N |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p23141-f1 | 1 | P23141 | 99.82 | 0.0 | GLY | A:190 | A:190 | 0.0 | 0.0 | H | -60.2 | -43.7 | |
| af-q9uky3-f1 | 1 | Q9UKY3 | 93.63 | 3e-170 | GLY | A:191 | A:191 | 0.0 | 0.0 | H | -64.1 | -40.0 | |