Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55855413 . C A CCDS32450.1:NM_001025195.1:c.560cGg>cTg_NP_001020366.1:p.187R>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ARG A:168 A:1186 98.0 0.436 -58.1 -45.2 48.0 0.213 0.223 C:P23141:0.222
 HOH
 2.889
 O
 O
ARG B:168 B:2186 94.0 0.418 -55.9 -43.0 46.0 0.204 0.214 A:P23141:0.213
 HOH
 2.841
 NH1
 O
ARG C:168 C:3186 91.0 0.404 -57.6 -41.0 42.0 0.187 0.217 B:P23141:0.218
 HOH
 3.004
 NH1
 O
ARG D:168 D:4186 91.0 0.404 -53.9 -47.6 41.0 0.182 0.222 F:P23141:0.222
 HOH
 2.875
 NH1
 O
ARG E:168 E:5186 99.0 0.44 -53.9 -43.9 49.0 0.218 0.222 D:P23141:0.222
 HOH
 2.650
 NH2
 O
ARG F:168 F:6186 96.0 0.427 -55.1 -44.8 46.0 0.204 0.223 E:P23141:0.222
 HOH
 2.922
 N
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:168 A:1186 93.0 0.413 -45.3 -49.6 46.0 0.204 0.209 C:P23141:0.209
 HOH
 2.903
 NH1
 O
ARG B:168 B:2186 93.0 0.413 -63.7 -41.6 44.0 0.196 0.217 A:P23141:0.218
 HOH
 2.575
 O
 O
ARG C:168 C:3186 97.0 0.431 -55.0 -48.5 50.0 0.222 0.209 B:P23141:0.209
 HOH
 2.867
 O
 O
ARG D:168 D:4186 98.0 0.436 -60.7 -45.1 NA NA NA
ARG E:168 E:5186 99.0 0.44 -47.5 -55.4 NA NA NA
ARG F:168 F:6186 98.0 0.436 -51.7 -49.7 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:168 A:1186 101.0 0.449 -49.3 -68.9 46.0 0.204 0.245 C:P23141:0.244
 HOH
 4.492
 NH1
 O
ARG B:168 B:2186 93.0 0.413 -55.3 -50.3 45.0 0.2 0.213 A:P23141:0.213
 HOH
 2.873
 NH1
 O
ARG C:168 C:3186 96.0 0.427 -53.0 -49.5 48.0 0.213 0.214 B:P23141:0.213
 HOH
 3.069
 CB
 O
ARG D:168 D:4186 90.0 0.4 -47.6 -67.6 46.0 0.204 0.196 F:P23141:0.196
 HOH
 2.873
 NH1
 O
ARG E:168 E:5186 90.0 0.4 -49.7 -45.5 37.0 0.164 0.236 D:P23141:0.236
 HOH
 2.574
 O
 O
ARG F:168 F:6186 90.0 0.4 -48.7 -40.7 44.0 0.196 0.204 E:P23141:0.204
 HOH
 2.592
 O
 O
ARG G:168 G:1186 92.0 0.409 -49.5 -57.2 NA NA NA
ARG H:168 H:2186 92.0 0.409 -70.0 -30.2 NA NA NA
ARG I:168 I:3186 99.0 0.44 -53.1 -62.6 NA NA NA
ARG J:168 J:4186 97.0 0.431 -49.0 -42.0 NA NA NA
ARG K:168 K:5186 91.0 0.404 -60.3 -53.3 NA NA NA
ARG L:168 L:6186 84.0 0.373 -49.4 -60.9 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:168 A:1186 94.0 0.418 -41.2 -52.1 49.0 0.218 0.2 C:P23141:0.2
 HOH
 3.100
 NH1
 O
ARG B:168 B:2186 96.0 0.427 -42.0 -49.1 47.0 0.209 0.218 A:P23141:0.218
 HOH
 2.799
 NH2
 O
ARG C:168 C:3186 96.0 0.427 -42.3 -50.0 49.0 0.218 0.209 B:P23141:0.209
 HOH
 2.923
 NH1
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:168 A:1186 103.0 0.458 -52.9 -56.9 53.0 0.236 0.222 C:P23141:0.222
 HOH
 2.584
 O
 O
ARG B:168 B:2186 103.0 0.458 -50.1 -49.4 51.0 0.227 0.231 A:P23141:0.231
 HOH
 3.044
 NH1
 O
ARG C:168 C:3186 99.0 0.44 -52.4 -47.4 52.0 0.231 0.209 B:P23141:0.209
 HOH
 2.741
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:168 A:1186 103.0 0.458 -46.3 -55.6 54.0 0.24 0.218 C:P23141:0.218
 HOH
 2.752
 N
 O
ARG B:168 B:2186 102.0 0.453 -49.0 -53.5 48.0 0.213 0.24 A:P23141:0.24
 HOH
 2.818
 N
 O
ARG C:168 C:3186 102.0 0.453 -48.3 -53.4 54.0 0.24 0.213 B:P23141:0.213
 HOH
 4.550
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:168 A:1186 99.0 0.44 -53.1 -41.1 50.0 0.222 0.218 C:P23141:0.218
 HOH
 2.916
 O
 O
ARG B:168 B:2186 95.0 0.422 -54.0 -42.6 41.0 0.182 0.24 A:P23141:0.24
 HOH
 2.610
 NH1
 O
ARG C:168 C:3186 96.0 0.427 -54.4 -45.0 46.0 0.204 0.223 B:P23141:0.222
 HOH
 2.705
 NH1
 O
ARG D:168 D:4186 100.0 0.444 -55.9 -45.5 51.0 0.227 0.217 E:P23141:0.218
 HOH
 2.847
 O
 O
ARG E:168 E:5186 96.0 0.427 -53.6 -46.1 47.0 0.209 0.218 F:P23141:0.218
 HOH
 2.517
 NH1
 O
ARG F:168 F:6186 98.0 0.436 -52.1 -44.3 46.0 0.204 0.232 D:P23141:0.231
 HOH
 2.696
 NH1
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:166 A:186 97.0 0.431 -49.5 -51.6 50.0 0.222 0.209 C:P23141:0.209
 HOH
 3.137
 NE
 O
ARG B:166 B:186 95.0 0.422 -61.9 -46.0 46.0 0.204 0.218 A:P23141:0.218
 HOH
 3.584
 NE
 O
ARG C:166 C:186 96.0 0.427 -53.2 -53.8 50.0 0.222 0.205 B:P23141:0.204
 HOH
 3.433
 NH2
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:166 A:186 94.0 0.418 -47.5 -60.8 49.0 0.218 0.2 C:P23141:0.2
 HOH
 3.191
 NH2
 O
ARG B:166 B:186 98.0 0.436 -45.4 -47.8 31.0 0.138 0.298 A:P23141:0.298
 HOH
 2.792
 N
 O
ARG C:166 C:186 96.0 0.427 -46.3 -52.4 45.0 0.2 0.227 B:P23141:0.227
 HOH
 2.728
 NH1
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:166 A:186 99.0 0.44 -54.3 -48.1 49.0 0.218 0.222 C:P23141:0.222
 HOH
 3.001
 N
 O
ARG B:166 B:186 98.0 0.436 -54.9 -40.8 49.0 0.218 0.218 A:P23141:0.218
 HOH
 2.755
 N
 O
ARG C:166 C:186 102.0 0.453 -53.4 -48.6 49.0 0.218 0.235 B:P23141:0.236
 HOH
 2.705
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:166 A:186 96.0 0.427 -44.4 -57.6 41.0 0.182 0.245 C:P23141:0.244
 HOH
 2.994
 CG
 O
ARG B:166 B:186 102.0 0.453 -45.3 -37.2 41.0 0.182 0.271 A:P23141:0.271
 HOH
 2.868
 N
 O
ARG C:166 C:186 105.0 0.467 -54.2 -47.5 57.0 0.253 0.214 B:P23141:0.213
 HOH
 3.626
 CG
 O
ARG D:166 D:186 89.0 0.396 -47.4 -44.6 NA NA NA
ARG E:166 E:186 93.0 0.413 -46.0 -28.9 NA NA NA
ARG F:166 F:186 101.0 0.449 -48.4 -41.1 NA NA NA
ARG G:166 G:186 105.0 0.467 -51.1 -43.9 NA NA NA
ARG H:166 H:186 96.0 0.427 -44.3 -52.7 NA NA NA
ARG I:166 I:186 90.0 0.4 -52.9 -35.0 NA NA NA
ARG J:166 J:186 106.0 0.471 -48.8 -46.2 NA NA NA
ARG K:166 K:186 95.0 0.422 -43.1 -49.6 NA NA NA
ARG L:166 L:186 102.0 0.453 -51.6 -31.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:166 A:1186 95.0 0.422 -58.8 -44.3 47.0 0.209 0.213 C:Q9UK77:0.213
 HOH
 2.732
 O
 O
ARG B:166 B:2186 103.0 0.458 -51.5 -43.6 47.0 0.209 0.249 A:Q9UK77:0.249
 HOH
 2.666
 O
 O
ARG C:166 C:3186 98.0 0.436 -54.1 -49.5 48.0 0.213 0.223 B:Q9UK77:0.222
 HOH
 2.663
 NH1
 O
ARG D:166 D:4186 96.0 0.427 -56.2 -49.5 NA NA NA
ARG E:166 E:5186 99.0 0.44 -51.2 -45.2 NA NA NA
ARG F:166 F:6186 97.0 0.431 -52.5 -47.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:166 A:1186 96.0 0.427 -55.4 -43.1 47.0 0.209 0.218 C:Q9UK77:0.218
 HOH
 2.959
 NH1
 O
ARG B:166 B:2186 96.0 0.427 -49.0 -41.5 47.0 0.209 0.218 A:Q9UK77:0.218
 HOH
 2.632
 O
 O
ARG C:166 C:3186 96.0 0.427 -54.3 -44.9 45.0 0.2 0.227 B:Q9UK77:0.227
 HOH
 2.827
 N
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ARG A:166 A:186 90.0 0.4 -53.3 -45.0 37.0 0.164 0.236 A:P23141:0.236
 SCN
HOH
 3.563
2.831
 NE
O
 S
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ARG A:166 A:186 106.0 0.471 -57.0 -41.7 48.0 0.213 0.258 A:P23141-3:0.258
 HOH
 2.747
 NH1
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:166 A:186 100.0 0.444 -54.4 -45.6 100.0 0.444 0.0 HOH
 2.807
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:165 A:186 98.0 0.436 -61.3 -44.2 98.0 0.436 0.0 IOD
HOH
 6.572
2.947
 CD
N
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ARG A:163 A:1186 100.0 0.444 -53.0 -56.9 49.0 0.218 0.226 C:P23141:0.227
 HOH
 2.741
 N
 O
ARG B:163 B:2186 104.0 0.462 -53.1 -56.4 54.0 0.24 0.222 A:P23141:0.222
 HOH
 6.916
 NH2
 O
ARG C:163 C:3186 103.0 0.458 -52.6 -56.3 50.0 0.222 0.236 B:P23141:0.236
 HOH
 2.874
 NH2
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ARG A:164 A:186 109.0 0.484 -50.7 -44.6 109.0 0.484 0.0 HOH
 3.175
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ARG A:186 A:186 106.0 0.471 -58.6 -36.8
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 PRO A:187 A:187 74.0 0.51 -58.1 -29.0