Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857462 . C A CCDS32450.1:NM_001025195.1:c.539aGc>aTc_NP_001020366.1:p.180S>I Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 SER A:161 A:1179 10.0 0.087 -132.8 136.2 10.0 0.087 0.0 HOH
 2.687
 O
 O
SER B:161 B:2179 11.0 0.096 -133.7 134.9 11.0 0.096 0.0 HOH
 2.568
 O
 O
SER C:161 C:3179 10.0 0.087 -137.9 134.8 10.0 0.087 0.0 HOH
 2.753
 O
 O
SER D:161 D:4179 10.0 0.087 -129.8 136.7 10.0 0.087 0.0 HOH
 2.814
 N
 O
SER E:161 E:5179 11.0 0.096 -127.2 140.9 11.0 0.096 0.0 HOH
 2.528
 O
 O
SER F:161 F:6179 11.0 0.096 -138.6 134.0 11.0 0.096 0.0 HOH
 2.811
 N
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 SER A:161 A:1179 11.0 0.096 -135.3 146.6 11.0 0.096 0.0 HOH
 3.916
 OG
 O
SER B:161 B:2179 9.0 0.078 -134.6 131.1 9.0 0.078 0.0 SIA
HOH
 9.038
2.723
 C
OG
 O9
O
SER C:161 C:3179 10.0 0.087 -142.7 139.3 10.0 0.087 0.0 SIA
HOH
 9.738
3.373
 O
OG
 O9
O
SER D:161 D:4179 10.0 0.087 -132.2 130.5 NA NA NA
SER E:161 E:5179 9.0 0.078 -145.4 130.0 NA NA NA
SER F:161 F:6179 9.0 0.078 -134.3 145.4 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 SER A:161 A:1179 14.0 0.122 -143.7 141.8 14.0 0.122 0.0 HOH
 8.230
 O
 O
SER B:161 B:2179 10.0 0.087 -144.9 141.4 10.0 0.087 0.0 HOH
 3.075
 O
 O
SER C:161 C:3179 6.0 0.052 -137.4 149.1 6.0 0.052 0.0 HOH
 2.820
 N
 O
SER D:161 D:4179 11.0 0.096 -139.2 141.6 11.0 0.096 0.0 HOH
 2.553
 O
 O
SER E:161 E:5179 7.0 0.061 -151.7 154.2 7.0 0.061 0.0 HOH
 4.480
 CB
 O
SER F:161 F:6179 9.0 0.078 -128.9 146.2 9.0 0.078 0.0 HOH
 3.217
 OG
 O
SER G:161 G:1179 12.0 0.104 -144.0 154.9 NA NA NA
SER H:161 H:2179 11.0 0.096 -138.1 149.3 NA NA NA
SER I:161 I:3179 13.0 0.113 -130.4 132.8 NA NA NA
SER J:161 J:4179 12.0 0.104 -148.3 138.7 NA NA NA
SER K:161 K:5179 10.0 0.087 -137.4 130.1 NA NA NA
SER L:161 L:6179 10.0 0.087 -136.1 135.4 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:161 A:1179 5.0 0.043 -127.9 135.7 5.0 0.043 0.0 HOH
 4.174
 CB
 O
SER B:161 B:2179 8.0 0.07 -127.7 135.2 8.0 0.07 0.0 HOH
 3.865
 CB
 O
SER C:161 C:3179 11.0 0.096 -128.5 135.6 11.0 0.096 0.0 HOH
 3.820
 CB
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:161 A:1179 13.0 0.113 -125.9 127.4 13.0 0.113 0.0 HOH
 3.295
 OG
 O
SER B:161 B:2179 11.0 0.096 -130.2 133.9 11.0 0.096 0.0 NAG
HOH
 9.500
4.082
 OG
CB
 C8
O
SER C:161 C:3179 11.0 0.096 -135.0 130.9 11.0 0.096 0.0 HOH
 3.542
 OG
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:161 A:1179 12.0 0.104 -145.1 140.8 12.0 0.104 0.0 HOH
 4.345
 CB
 O
SER B:161 B:2179 12.0 0.104 -143.6 141.5 12.0 0.104 0.0 HOH
 4.354
 CB
 O
SER C:161 C:3179 12.0 0.104 -142.6 140.6 12.0 0.104 0.0 HOH
 4.010
 CB
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:161 A:1179 10.0 0.087 -135.6 139.6 10.0 0.087 0.0 HOH
 2.637
 O
 O
SER B:161 B:2179 10.0 0.087 -136.2 134.4 10.0 0.087 0.0 HOH
 2.717
 N
 O
SER C:161 C:3179 10.0 0.087 -140.5 134.8 10.0 0.087 0.0 HOH
 2.672
 O
 O
SER D:161 D:4179 10.0 0.087 -139.3 134.5 10.0 0.087 0.0 HOH
 2.649
 O
 O
SER E:161 E:5179 10.0 0.087 -140.1 135.8 10.0 0.087 0.0 HOH
 2.688
 O
 O
SER F:161 F:6179 11.0 0.096 -135.4 137.0 11.0 0.096 0.0 HOH
 2.745
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:159 A:179 12.0 0.104 -134.9 139.5 12.0 0.104 0.0 HOH
 4.692
 CB
 O
SER B:159 B:179 11.0 0.096 -136.1 144.1 11.0 0.096 0.0 HOH
 7.855
 OG
 O
SER C:159 C:179 11.0 0.096 -131.4 133.7 11.0 0.096 0.0 HOH
 4.026
 CB
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:159 A:179 6.0 0.052 -144.4 135.9 6.0 0.052 0.0 HOH
 4.367
 CB
 O
SER B:159 B:179 7.0 0.061 -142.9 135.1 7.0 0.061 0.0 HOH
 4.012
 CB
 O
SER C:159 C:179 11.0 0.096 -135.6 136.4 11.0 0.096 0.0 HOH
 3.823
 CB
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:159 A:179 12.0 0.104 -135.1 130.5 12.0 0.104 0.0 HOH
 4.367
 CB
 O
SER B:159 B:179 11.0 0.096 -138.7 128.2 11.0 0.096 0.0 HOH
 4.234
 CB
 O
SER C:159 C:179 10.0 0.087 -142.2 130.4 10.0 0.087 0.0 HOH
 2.713
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:159 A:179 8.0 0.07 -123.8 143.4 8.0 0.07 0.0 SIA
HOH
 9.888
8.631
 O
OG
 O10
O
SER B:159 B:179 12.0 0.104 -141.0 135.8 12.0 0.104 0.0 HOH
 4.517
 CB
 O
SER C:159 C:179 12.0 0.104 -125.1 148.0 12.0 0.104 0.0 HOH
 4.367
 CB
 O
SER D:159 D:179 12.0 0.104 -141.4 129.2 NA NA NA
SER E:159 E:179 12.0 0.104 -138.8 130.5 NA NA NA
SER F:159 F:179 11.0 0.096 -132.0 140.4 NA NA NA
SER G:159 G:179 11.0 0.096 -131.1 150.2 NA NA NA
SER H:159 H:179 7.0 0.061 -121.2 137.7 NA NA NA
SER I:159 I:179 8.0 0.07 -123.1 142.2 NA NA NA
SER J:159 J:179 12.0 0.104 -124.8 143.9 NA NA NA
SER K:159 K:179 9.0 0.078 -131.7 137.0 NA NA NA
SER L:159 L:179 11.0 0.096 -103.6 139.6 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 SER A:159 A:1179 10.0 0.087 -138.5 127.4 10.0 0.087 0.0 HOH
 2.627
 N
 O
SER B:159 B:2179 11.0 0.096 -141.2 128.4 11.0 0.096 0.0 HOH
 3.089
 N
 O
SER C:159 C:3179 9.0 0.078 -134.5 138.8 9.0 0.078 0.0 HOH
 2.723
 N
 O
SER D:159 D:4179 11.0 0.096 -140.7 129.7 NA NA NA
SER E:159 E:5179 10.0 0.087 -139.9 128.5 NA NA NA
SER F:159 F:6179 11.0 0.096 -132.5 140.1 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 SER A:159 A:1179 5.0 0.043 -142.5 131.8 5.0 0.043 0.0 HOH
 3.050
 N
 O
SER B:159 B:2179 10.0 0.087 -133.0 131.3 10.0 0.087 0.0 HOH
 2.993
 N
 O
SER C:159 C:3179 9.0 0.078 -141.0 130.0 9.0 0.078 0.0 HOH
 2.869
 N
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 SER A:159 A:179 9.0 0.078 -139.0 130.6 9.0 0.078 0.0 SCN
HOH
 8.224
2.707
 OG
O
 S
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 SER A:159 A:179 9.0 0.078 -134.9 132.5 9.0 0.078 0.0 HOH
 2.931
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 SER A:159 A:179 8.0 0.07 -138.7 129.9 8.0 0.07 0.0 HOH
 2.755
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 SER A:158 A:179 10.0 0.087 -133.3 133.2 10.0 0.087 0.0 HOH
 2.868
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 SER A:156 A:1179 12.0 0.104 -137.7 145.9 12.0 0.104 0.0 HOH
 7.800
 CA
 O
SER B:156 B:2179 12.0 0.104 -138.0 146.3 12.0 0.104 0.0
SER C:156 C:3179 13.0 0.113 -137.9 146.6 13.0 0.113 0.0 HOH
 4.058
 CB
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 SER A:157 A:179 2.0 0.017 -136.1 138.7 2.0 0.017 0.0 HOH
 2.503
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 SER A:179 A:179 9.0 0.078 -130.5 136.6
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 SER A:180 A:180 28.0 0.243 -137.4 133.1