Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857472 . C A CCDS32450.1:NM_001025195.1:c.529Gga>Tga_NP_001020366.1:p.177G>* Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:158 A:1176 0.0 0.0 H -100.5 -15.4 0.0 0.0 0.0 HOH
 4.819
 O
 O
GLY B:158 B:2176 0.0 0.0 H -97.1 -15.7 0.0 0.0 0.0 HOH
 4.852
 N
 O
GLY C:158 C:3176 0.0 0.0 H -93.9 -21.8 0.0 0.0 0.0 HOH
 4.825
 O
 O
GLY D:158 D:4176 0.0 0.0 H -99.6 -17.1 0.0 0.0 0.0 HOH
 4.796
 O
 O
GLY E:158 E:5176 0.0 0.0 H -97.9 -16.7 0.0 0.0 0.0 HOH
 4.733
 O
 O
GLY F:158 F:6176 0.0 0.0 H -98.3 -14.7 0.0 0.0 0.0 HOH
 4.786
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:158 A:1176 0.0 0.0 H -102.5 -6.3 0.0 0.0 0.0 HOH
 4.563
 O
 O
GLY B:158 B:2176 0.0 0.0 H -97.9 -9.9 0.0 0.0 0.0 HOH
 4.556
 O
 O
GLY C:158 C:3176 0.0 0.0 H -101.0 -10.8 0.0 0.0 0.0 HOH
 4.675
 O
 O
GLY D:158 D:4176 0.0 0.0 H -96.4 -14.6 NA NA NA
GLY E:158 E:5176 0.0 0.0 H -95.8 -9.1 NA NA NA
GLY F:158 F:6176 0.0 0.0 H -106.0 -8.6 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:158 A:1176 0.0 0.0 H -102.1 -1.5 0.0 0.0 0.0 HOH
 6.619
 N
 O
GLY B:158 B:2176 0.0 0.0 H -91.9 -30.5 0.0 0.0 0.0 HOH
 4.724
 N
 O
GLY C:158 C:3176 0.0 0.0 H -90.8 -9.3 0.0 0.0 0.0 HOH
 4.687
 O
 O
GLY D:158 D:4176 0.0 0.0 H -106.6 -7.0 0.0 0.0 0.0 HOH
 4.717
 N
 O
GLY E:158 E:5176 0.0 0.0 H -105.3 -10.0 0.0 0.0 0.0 HOH
 4.896
 N
 O
GLY F:158 F:6176 0.0 0.0 H -108.1 -7.8 0.0 0.0 0.0 HOH
 4.787
 O
 O
GLY G:158 G:1176 0.0 0.0 H -99.9 -13.0 NA NA NA
GLY H:158 H:2176 0.0 0.0 H -103.4 -10.6 NA NA NA
GLY I:158 I:3176 0.0 0.0 H -90.1 -36.6 NA NA NA
GLY J:158 J:4176 0.0 0.0 H -102.7 -9.5 NA NA NA
GLY K:158 K:5176 0.0 0.0 H -103.6 -15.1 NA NA NA
GLY L:158 L:6176 0.0 0.0 H -123.0 -23.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:158 A:1176 0.0 0.0 H -114.9 -0.4 0.0 0.0 0.0 HOH
 5.027
 O
 O
GLY B:158 B:2176 0.0 0.0 H -114.1 -0.4 0.0 0.0 0.0 HOH
 4.721
 N
 O
GLY C:158 C:3176 0.0 0.0 H -115.8 -1.2 0.0 0.0 0.0 HOH
 4.786
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:158 A:1176 0.0 0.0 H -103.5 -15.5 0.0 0.0 0.0 HOH
 4.514
 O
 O
GLY B:158 B:2176 0.0 0.0 H -111.4 5.1 0.0 0.0 0.0 HOH
 5.003
 N
 O
GLY C:158 C:3176 0.0 0.0 H -100.4 -13.1 0.0 0.0 0.0 HOH
 4.953
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:158 A:1176 0.0 0.0 H -111.9 -1.0 0.0 0.0 0.0 HOH
 4.885
 N
 O
GLY B:158 B:2176 0.0 0.0 H -111.0 -1.7 0.0 0.0 0.0 HOH
 4.679
 O
 O
GLY C:158 C:3176 0.0 0.0 H -111.2 -0.4 0.0 0.0 0.0 HOH
 4.989
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:158 A:1176 0.0 0.0 H -89.0 -21.1 0.0 0.0 0.0 HOH
 4.810
 O
 O
GLY B:158 B:2176 0.0 0.0 H -97.5 -18.2 0.0 0.0 0.0 HOH
 4.868
 N
 O
GLY C:158 C:3176 0.0 0.0 H -97.0 -17.8 0.0 0.0 0.0 HOH
 4.823
 N
 O
GLY D:158 D:4176 0.0 0.0 H -97.5 -15.8 0.0 0.0 0.0 HOH
 4.704
 N
 O
GLY E:158 E:5176 0.0 0.0 H -98.5 -18.0 0.0 0.0 0.0 HOH
 4.746
 O
 O
GLY F:158 F:6176 0.0 0.0 H -91.6 -24.5 0.0 0.0 0.0 HOH
 4.719
 N
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:156 A:176 0.0 0.0 H -108.5 -10.5 0.0 0.0 0.0 HOH
 4.643
 O
 O
GLY B:156 B:176 0.0 0.0 H -105.5 -8.8 0.0 0.0 0.0 HOH
 4.524
 N
 O
GLY C:156 C:176 0.0 0.0 H -104.3 -5.0 0.0 0.0 0.0 HOH
 4.815
 N
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:156 A:176 0.0 0.0 H -115.6 -0.7 0.0 0.0 0.0 HOH
 4.381
 O
 O
GLY B:156 B:176 0.0 0.0 H -113.4 -7.5 0.0 0.0 0.0 HOH
 4.603
 O
 O
GLY C:156 C:176 0.0 0.0 H -103.8 -5.9 0.0 0.0 0.0 HOH
 4.795
 N
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:156 A:176 0.0 0.0 H -106.5 2.0 0.0 0.0 0.0 HOH
 4.743
 O
 O
GLY B:156 B:176 0.0 0.0 H -103.7 -10.6 0.0 0.0 0.0 HOH
 4.712
 O
 O
GLY C:156 C:176 0.0 0.0 H -105.6 -9.4 0.0 0.0 0.0 HOH
 4.624
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:156 A:176 0.0 0.0 H -95.8 -29.8 0.0 0.0 0.0 HOH
 8.921
 CA
 O
GLY B:156 B:176 0.0 0.0 H -109.9 -7.8 0.0 0.0 0.0 HOH
 4.536
 O
 O
GLY C:156 C:176 0.0 0.0 H -112.1 -5.9 0.0 0.0 0.0 HOH
 4.407
 O
 O
GLY D:156 D:176 0.0 0.0 H -110.8 -8.1 NA NA NA
GLY E:156 E:176 0.0 0.0 H -112.0 -4.5 NA NA NA
GLY F:156 F:176 0.0 0.0 H -105.7 -8.0 NA NA NA
GLY G:156 G:176 0.0 0.0 H -104.0 -16.2 NA NA NA
GLY H:156 H:176 0.0 0.0 H -115.3 -12.9 NA NA NA
GLY I:156 I:176 0.0 0.0 H -127.3 -8.0 NA NA NA
GLY J:156 J:176 0.0 0.0 H -112.0 -0.3 NA NA NA
GLY K:156 K:176 0.0 0.0 H -110.4 -4.2 NA NA NA
GLY L:156 L:176 0.0 0.0 H -120.9 -17.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:156 A:1176 0.0 0.0 H -91.1 -16.7 0.0 0.0 0.0 HOH
 4.745
 O
 O
GLY B:156 B:2176 0.0 0.0 H -104.5 -9.8 0.0 0.0 0.0 HOH
 4.788
 N
 O
GLY C:156 C:3176 0.0 0.0 H -94.1 -12.4 0.0 0.0 0.0 HOH
 4.812
 O
 O
GLY D:156 D:4176 0.0 0.0 H -93.7 -15.3 NA NA NA
GLY E:156 E:5176 0.0 0.0 H -98.3 -11.3 NA NA NA
GLY F:156 F:6176 0.0 0.0 H -101.4 -8.6 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:156 A:1176 0.0 0.0 H -97.1 -3.2 0.0 0.0 0.0 HOH
 4.524
 N
 O
GLY B:156 B:2176 0.0 0.0 H -98.1 -8.6 0.0 0.0 0.0 HOH
 4.779
 N
 O
GLY C:156 C:3176 0.0 0.0 H -91.6 -13.2 0.0 0.0 0.0 HOH
 4.919
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:156 A:176 0.0 0.0 H -94.0 -27.7 0.0 0.0 0.0 HOH
 4.780
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:156 A:176 0.0 0.0 H -85.0 -24.7 0.0 0.0 0.0 HOH
 4.842
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:156 A:176 0.0 0.0 H -91.6 -21.0 0.0 0.0 0.0 HOH
 4.791
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:155 A:176 0.0 0.0 H -78.1 -32.7 0.0 0.0 0.0 HOH
 4.767
 O
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:153 A:1176 0.0 0.0 H -115.2 -3.0 0.0 0.0 0.0 HOH
 4.741
 N
 O
GLY B:153 B:2176 0.0 0.0 H -117.3 -0.9 0.0 0.0 0.0 HOH
 7.183
 N
 O
GLY C:153 C:3176 0.0 0.0 H -116.0 -2.2 0.0 0.0 0.0 HOH
 4.769
 O
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:154 A:176 0.0 0.0 H -95.9 -21.1 0.0 0.0 0.0 HOH
 4.742
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:176 A:176 0.0 0.0 H -89.1 -29.9
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:177 A:177 0.0 0.0 H -87.5 -29.9