Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 55857477 | . | A | C | CCDS32450.1:NM_001025195.1:c.524aTc>aGc_NP_001020366.1:p.175I>S | Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1mx1 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-22 | ILE | A:156 | A:1174 | 0.0 | 0.0 | H | -51.6 | -48.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.761 |
N |
O |
||
| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -53.0 | -50.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.788 |
N |
O |
|||||||||
| ILE | C:156 | C:3174 | 0.0 | 0.0 | H | -56.5 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.933 |
N |
O |
|||||||||
| ILE | D:156 | D:4174 | 0.0 | 0.0 | H | -54.6 | -49.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.800 |
N |
O |
|||||||||
| ILE | E:156 | E:5174 | 0.0 | 0.0 | H | -59.1 | -49.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.943 |
N |
O |
|||||||||
| ILE | F:156 | F:6174 | 0.0 | 0.0 | H | -55.2 | -42.3 | 0.0 | 0.0 | 0.0 |
HOH |
2.844 |
N |
O |
|||||||||
| 1mx5 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ILE | A:156 | A:1174 | 0.0 | 0.0 | H | -47.4 | -46.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.971 |
N |
O |
||
| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -45.1 | -51.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.007 |
N |
O |
|||||||||
| ILE | C:156 | C:3174 | 0.0 | 0.0 | H | -61.5 | -48.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.839 |
N |
O |
|||||||||
| ILE | D:156 | D:4174 | 0.0 | 0.0 | H | -48.4 | -55.8 | NA | NA | NA | |||||||||||||
| ILE | E:156 | E:5174 | 0.0 | 0.0 | H | -52.2 | -42.9 | NA | NA | NA | |||||||||||||
| ILE | F:156 | F:6174 | 0.0 | 0.0 | H | -46.0 | -52.0 | NA | NA | NA | |||||||||||||
| 1mx9 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ILE | A:156 | A:1174 | 0.0 | 0.0 | H | -60.6 | -53.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.916 |
N |
O |
||
| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -48.0 | -55.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.353 |
N |
O |
|||||||||
| ILE | C:156 | C:3174 | 0.0 | 0.0 | H | -38.5 | -55.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.670 |
N |
O |
|||||||||
| ILE | D:156 | D:4174 | 0.0 | 0.0 | H | -48.9 | -60.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.750 |
N |
O |
|||||||||
| ILE | E:156 | E:5174 | 0.0 | 0.0 | H | -52.2 | -46.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.719 |
N |
O |
|||||||||
| ILE | F:156 | F:6174 | 0.0 | 0.0 | H | -44.0 | -49.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.757 |
N |
O |
|||||||||
| ILE | G:156 | G:1174 | 0.0 | 0.0 | H | -47.1 | -55.5 | NA | NA | NA | |||||||||||||
| ILE | H:156 | H:2174 | 0.0 | 0.0 | H | -46.0 | -50.0 | NA | NA | NA | |||||||||||||
| ILE | I:156 | I:3174 | 0.0 | 0.0 | H | -50.1 | -56.0 | NA | NA | NA | |||||||||||||
| ILE | J:156 | J:4174 | 0.0 | 0.0 | H | -46.1 | -44.2 | NA | NA | NA | |||||||||||||
| ILE | K:156 | K:5174 | 0.0 | 0.0 | H | -47.3 | -38.2 | NA | NA | NA | |||||||||||||
| ILE | L:156 | L:6174 | 0.0 | 0.0 | H | -49.7 | -57.5 | NA | NA | NA | |||||||||||||
| 2dqy | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ILE | A:156 | A:1174 | 0.0 | 0.0 | H | -52.9 | -53.2 | 0.0 | 0.0 | 0.0 |
PLM HOH |
9.110 2.928 |
CG1 N |
CF O |
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| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -52.2 | -52.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.531 |
N |
O |
|||||||||
| ILE | C:156 | C:3174 | 0.0 | 0.0 | H | -51.9 | -53.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.688 |
N |
O |
|||||||||
| 2dqz | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ILE | A:156 | A:1174 | 0.0 | 0.0 | H | -57.1 | -45.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.926 |
N |
O |
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| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -49.2 | -46.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.720 |
N |
O |
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| ILE | C:156 | C:3174 | 0.0 | 0.0 | H | -54.3 | -44.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.865 |
N |
O |
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| 2dr0 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ILE | A:156 | A:1174 | 2.0 | 0.011 | H | -56.0 | -52.6 | 2.0 | 0.011 | 0.0 |
HOH |
3.185 |
N |
O |
||
| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -54.5 | -51.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.940 |
N |
O |
|||||||||
| ILE | C:156 | C:3174 | 4.0 | 0.023 | H | -54.4 | -53.6 | 4.0 | 0.023 | 0.0 |
HOH |
2.825 |
N |
O |
|||||||||
| 2h7c | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ILE | A:156 | A:1174 | 0.0 | 0.0 | H | -55.9 | -47.8 | 0.0 | 0.0 | 0.0 |
COA HOH |
9.881 2.938 |
N N |
O4A O |
||
| ILE | B:156 | B:2174 | 0.0 | 0.0 | H | -53.3 | -47.0 | 0.0 | 0.0 | 0.0 |
COA HOH |
9.753 2.880 |
N N |
O4A O |
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| ILE | C:156 | C:3174 | 0.0 | 0.0 | H | -55.2 | -48.8 | 0.0 | 0.0 | 0.0 |
COA HOH |
9.939 2.935 |
N N |
O4A O |
|||||||||
| ILE | D:156 | D:4174 | 0.0 | 0.0 | H | -55.6 | -45.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.835 |
N |
O |
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| ILE | E:156 | E:5174 | 0.0 | 0.0 | H | -55.9 | -44.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.883 |
N |
O |
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| ILE | F:156 | F:6174 | 0.0 | 0.0 | H | -53.5 | -49.1 | 0.0 | 0.0 | 0.0 |
COA HOH |
9.993 2.881 |
N N |
O4A O |
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| 1ya4 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -55.7 | -46.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.844 |
N |
O |
||
| ILE | B:154 | B:174 | 0.0 | 0.0 | H | -57.3 | -43.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.329 |
O |
O |
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| ILE | C:154 | C:174 | 0.0 | 0.0 | H | -53.2 | -48.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.496 |
N |
O |
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| 1ya8 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -51.9 | -53.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.944 |
N |
O |
||
| ILE | B:154 | B:174 | 0.0 | 0.0 | H | -55.4 | -45.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.510 |
O |
O |
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| ILE | C:154 | C:174 | 0.0 | 0.0 | H | -53.9 | -48.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.955 |
N |
O |
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| 1yah | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -47.4 | -57.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.208 |
N |
O |
||
| ILE | B:154 | B:174 | 0.0 | 0.0 | H | -51.6 | -52.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.782 |
N |
O |
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| ILE | C:154 | C:174 | 0.0 | 0.0 | H | -50.5 | -50.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.961 |
N |
O |
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| 1yaj | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -39.2 | -59.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.892 |
N |
O |
||
| ILE | B:154 | B:174 | 0.0 | 0.0 | H | -56.7 | -52.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.906 |
O |
O |
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| ILE | C:154 | C:174 | 0.0 | 0.0 | H | -45.2 | -47.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.701 |
N |
O |
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| ILE | D:154 | D:174 | 1.0 | 0.006 | H | -53.8 | -35.2 | NA | NA | NA | |||||||||||||
| ILE | E:154 | E:174 | 0.0 | 0.0 | H | -49.1 | -52.1 | NA | NA | NA | |||||||||||||
| ILE | F:154 | F:174 | 0.0 | 0.0 | H | -47.0 | -41.1 | NA | NA | NA | |||||||||||||
| ILE | G:154 | G:174 | 0.0 | 0.0 | H | -45.3 | -51.7 | NA | NA | NA | |||||||||||||
| ILE | H:154 | H:174 | 0.0 | 0.0 | H | -43.1 | -46.9 | NA | NA | NA | |||||||||||||
| ILE | I:154 | I:174 | 1.0 | 0.006 | H | -53.0 | -55.3 | NA | NA | NA | |||||||||||||
| ILE | J:154 | J:174 | 0.0 | 0.0 | H | -38.9 | -53.1 | NA | NA | NA | |||||||||||||
| ILE | K:154 | K:174 | 0.0 | 0.0 | H | -46.8 | -42.9 | NA | NA | NA | |||||||||||||
| ILE | L:154 | L:174 | 0.0 | 0.0 | H | -60.1 | -35.2 | NA | NA | NA | |||||||||||||
| 2hrq | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ILE | A:154 | A:1174 | 0.0 | 0.0 | H | -56.3 | -51.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.796 |
N |
O |
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| ILE | B:154 | B:2174 | 0.0 | 0.0 | H | -55.2 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.838 |
N |
O |
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| ILE | C:154 | C:3174 | 0.0 | 0.0 | H | -44.7 | -52.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.013 |
N |
O |
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| ILE | D:154 | D:4174 | 0.0 | 0.0 | H | -56.2 | -53.7 | NA | NA | NA | |||||||||||||
| ILE | E:154 | E:5174 | 0.0 | 0.0 | H | -54.9 | -42.5 | NA | NA | NA | |||||||||||||
| ILE | F:154 | F:6174 | 0.0 | 0.0 | H | -51.4 | -47.2 | NA | NA | NA | |||||||||||||
| 2hrr | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ILE | A:154 | A:1174 | 0.0 | 0.0 | H | -53.2 | -52.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.968 |
N |
O |
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| ILE | B:154 | B:2174 | 0.0 | 0.0 | H | -49.3 | -49.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.922 |
N |
O |
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| ILE | C:154 | C:3174 | 0.0 | 0.0 | H | -51.5 | -48.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.689 |
N |
O |
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| 4ab1 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2012-03-07 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -51.7 | -45.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.698 |
N |
O |
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| 5a7f | 1 | P23141-3 | 99.81 | 0.0 |
X-RAY |
2016-01-13 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -56.6 | -47.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.908 |
N |
O |
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| 5a7g | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ILE | A:154 | A:174 | 0.0 | 0.0 | H | -55.9 | -48.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.905 |
N |
O |
||
| 5a7h | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ILE | A:153 | A:174 | 0.0 | 0.0 | H | -50.4 | -47.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.076 |
N |
O |
||
| 3k9b | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2010-01-19 | ILE | A:151 | A:1174 | 1.0 | 0.006 | H | -49.4 | -47.4 | 1.0 | 0.006 | 0.0 |
HOH |
3.711 |
N |
O |
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| ILE | B:151 | B:2174 | 1.0 | 0.006 | H | -49.1 | -48.5 | 1.0 | 0.006 | 0.0 |
HOH |
3.222 |
N |
O |
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| ILE | C:151 | C:3174 | 0.0 | 0.0 | H | -50.5 | -48.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.203 |
O |
O |
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| 1k4y | 1 | 3219695 | 82.06 | 0.0 |
X-RAY |
2002-05-01 | ILE | A:152 | A:174 | 0.0 | 0.0 | H | -57.3 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.888 |
N |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p23141-f1 | 1 | P23141 | 99.82 | 0.0 | ILE | A:174 | A:174 | 0.0 | 0.0 | H | -56.4 | -45.6 | |
| af-q9uky3-f1 | 1 | Q9UKY3 | 93.63 | 3e-170 | ILE | A:175 | A:175 | 76.0 | 0.434 | H | -56.9 | -43.6 | |