Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857480 . C A CCDS32450.1:NM_001025195.1:c.521gGc>gTc_NP_001020366.1:p.174G>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:155 A:1173 2.0 0.027 H 49.1 -138.3 2.0 0.027 0.0 HOH
 3.137
 CA
 O
GLY B:155 B:2173 3.0 0.04 H 47.9 -135.1 3.0 0.04 0.0 HOH
 3.284
 CA
 O
GLY C:155 C:3173 2.0 0.027 H 46.0 -134.5 2.0 0.027 0.0 HOH
 3.369
 CA
 O
GLY D:155 D:4173 3.0 0.04 H 44.5 -133.2 3.0 0.04 0.0 HOH
 3.326
 CA
 O
GLY E:155 E:5173 2.0 0.027 H 52.9 -134.4 2.0 0.027 0.0 HOH
 3.379
 CA
 O
GLY F:155 F:6173 2.0 0.027 H 48.2 -139.2 2.0 0.027 0.0 HOH
 3.176
 CA
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:155 A:1173 2.0 0.027 H 45.1 -139.7 2.0 0.027 0.0 HOH
 3.302
 CA
 O
GLY B:155 B:2173 2.0 0.027 H 42.2 -136.2 2.0 0.027 0.0 HOH
 3.553
 N
 O
GLY C:155 C:3173 3.0 0.04 H 47.6 -129.8 3.0 0.04 0.0 HTQ
HOH
 9.717
3.078
 N
CA
 C17
O
GLY D:155 D:4173 2.0 0.027 H 47.6 -134.7 NA NA NA
GLY E:155 E:5173 2.0 0.027 H 44.4 -140.2 NA NA NA
GLY F:155 F:6173 2.0 0.027 H 49.6 -140.3 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:155 A:1173 3.0 0.04 H 49.9 -136.5 3.0 0.04 0.0 HOH
 3.373
 CA
 O
GLY B:155 B:2173 2.0 0.027 H 32.5 -133.9 2.0 0.027 0.0 HOH
 3.174
 CA
 O
GLY C:155 C:3173 3.0 0.04 H 40.3 -144.0 3.0 0.04 0.0 HOH
 3.413
 CA
 O
GLY D:155 D:4173 2.0 0.027 H 44.0 -141.2 2.0 0.027 0.0 HOH
 3.279
 CA
 O
GLY E:155 E:5173 2.0 0.027 H 55.0 -141.3 2.0 0.027 0.0 HOH
 3.072
 CA
 O
GLY F:155 F:6173 4.0 0.053 H 42.9 -150.1 4.0 0.053 0.0 HOH
 3.347
 CA
 O
GLY G:155 G:1173 3.0 0.04 H 42.2 -137.1 NA NA NA
GLY H:155 H:2173 3.0 0.04 H 31.7 -137.2 NA NA NA
GLY I:155 I:3173 2.0 0.027 H 44.6 -138.0 NA NA NA
GLY J:155 J:4173 2.0 0.027 H 57.4 -156.2 NA NA NA
GLY K:155 K:5173 2.0 0.027 H 53.6 -151.0 NA NA NA
GLY L:155 L:6173 2.0 0.027 S 56.0 -145.1 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:155 A:1173 2.0 0.027 H 46.6 -136.5 2.0 0.027 0.0 PLM
HOH
 8.236
3.596
 CA
CA
 CE
O
GLY B:155 B:2173 2.0 0.027 H 46.8 -136.2 2.0 0.027 0.0 HOH
 3.135
 CA
 O
GLY C:155 C:3173 3.0 0.04 H 47.2 -136.9 3.0 0.04 0.0 HOH
 3.623
 CA
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:155 A:1173 2.0 0.027 H 42.5 -135.4 2.0 0.027 0.0 HOH
 3.395
 CA
 O
GLY B:155 B:2173 3.0 0.04 H 53.7 -140.4 3.0 0.04 0.0 HOH
 3.108
 CA
 O
GLY C:155 C:3173 3.0 0.04 H 48.7 -137.0 3.0 0.04 0.0 HOH
 3.292
 CA
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:155 A:1173 3.0 0.04 H 46.9 -138.9 3.0 0.04 0.0 HOH
 3.054
 CA
 O
GLY B:155 B:2173 3.0 0.04 H 46.5 -140.0 3.0 0.04 0.0 HOH
 4.698
 N
 O
GLY C:155 C:3173 2.0 0.027 H 47.0 -140.0 2.0 0.027 0.0 HOH
 3.153
 CA
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:155 A:1173 2.0 0.027 H 50.2 -133.7 2.0 0.027 0.0 COA
HOH
 8.592
3.378
 CA
CA
 O4A
O
GLY B:155 B:2173 2.0 0.027 H 50.3 -138.3 2.0 0.027 0.0 COA
HOH
 8.383
3.312
 CA
CA
 O4A
O
GLY C:155 C:3173 2.0 0.027 H 51.3 -134.5 2.0 0.027 0.0 COA
HOH
 8.617
3.400
 CA
CA
 O4A
O
GLY D:155 D:4173 2.0 0.027 H 51.2 -136.1 2.0 0.027 0.0 COA
HOH
 8.783
3.207
 CA
CA
 O4A
O
GLY E:155 E:5173 3.0 0.04 H 49.3 -134.4 3.0 0.04 0.0 COA
HOH
 8.731
3.414
 CA
CA
 O4A
O
GLY F:155 F:6173 3.0 0.04 H 55.2 -137.7 3.0 0.04 0.0 COA
HOH
 8.689
3.393
 CA
CA
 O4A
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:153 A:173 3.0 0.04 H 47.7 -142.1 3.0 0.04 0.0 HOH
 3.308
 CA
 O
GLY B:153 B:173 2.0 0.027 H 53.5 -145.3 2.0 0.027 0.0 HOH
 6.204
 CA
 O
GLY C:153 C:173 3.0 0.04 H 48.3 -142.3 3.0 0.04 0.0 HOH
 3.450
 CA
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:153 A:173 3.0 0.04 H 47.6 -138.0 3.0 0.04 0.0 HOH
 3.455
 CA
 O
GLY B:153 B:173 3.0 0.04 H 48.8 -137.9 3.0 0.04 0.0 HOH
 4.699
 N
 O
GLY C:153 C:173 4.0 0.053 H 44.5 -133.0 4.0 0.053 0.0 HOH
 3.398
 CA
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:153 A:173 2.0 0.027 H 47.1 -142.2 2.0 0.027 0.0 HOH
 3.364
 CA
 O
GLY B:153 B:173 3.0 0.04 H 53.4 -138.6 3.0 0.04 0.0 HOH
 3.248
 CA
 O
GLY C:153 C:173 2.0 0.027 H 46.9 -138.9 2.0 0.027 0.0 HOH
 3.198
 CA
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:153 A:173 2.0 0.027 H 46.7 -152.3 2.0 0.027 0.0 HOH
 5.625
 CA
 O
GLY B:153 B:173 3.0 0.04 H 49.7 -132.2 3.0 0.04 0.0 HOH
 5.947
 N
 O
GLY C:153 C:173 3.0 0.04 H 42.7 -148.2 3.0 0.04 0.0 HOH
 3.437
 CA
 O
GLY D:153 D:173 3.0 0.04 H 48.3 -142.3 NA NA NA
GLY E:153 E:173 2.0 0.027 T 71.0 -140.6 NA NA NA
GLY F:153 F:173 2.0 0.027 H 42.4 -152.0 NA NA NA
GLY G:153 G:173 3.0 0.04 H 42.5 -147.3 NA NA NA
GLY H:153 H:173 2.0 0.027 H 47.9 -149.5 NA NA NA
GLY I:153 I:173 2.0 0.027 T 56.5 -141.4 NA NA NA
GLY J:153 J:173 3.0 0.04 H 41.3 -147.0 NA NA NA
GLY K:153 K:173 2.0 0.027 H 51.8 -142.9 NA NA NA
GLY L:153 L:173 1.0 0.013 T 49.2 -140.9 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:153 A:1173 2.0 0.027 H 49.2 -129.2 2.0 0.027 0.0 HOH
 3.342
 CA
 O
GLY B:153 B:2173 3.0 0.04 H 48.8 -135.1 3.0 0.04 0.0 HOH
 3.244
 CA
 O
GLY C:153 C:3173 3.0 0.04 H 45.5 -139.1 3.0 0.04 0.0 HOH
 3.196
 CA
 O
GLY D:153 D:4173 2.0 0.027 H 47.8 -127.5 NA NA NA
GLY E:153 E:5173 3.0 0.04 H 46.3 -136.6 NA NA NA
GLY F:153 F:6173 3.0 0.04 H 44.3 -137.6 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:153 A:1173 2.0 0.027 H 39.8 -132.8 2.0 0.027 0.0 HOH
 3.419
 CA
 O
GLY B:153 B:2173 2.0 0.027 H 45.3 -137.9 2.0 0.027 0.0 HOH
 3.180
 N
 O
GLY C:153 C:3173 2.0 0.027 H 43.3 -135.8 2.0 0.027 0.0 HOH
 2.967
 CA
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:153 A:173 2.0 0.027 H 62.3 -143.6 2.0 0.027 0.0 HOH
 3.330
 CA
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:153 A:173 3.0 0.04 H 63.4 -138.9 3.0 0.04 0.0 HOH
 3.383
 CA
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:153 A:173 2.0 0.027 H 65.8 -139.3 2.0 0.027 0.0 HOH
 3.212
 CA
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:152 A:173 3.0 0.04 H 46.5 -137.4 3.0 0.04 0.0 HOH
 3.379
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:150 A:1173 4.0 0.053 H 44.5 -141.5 4.0 0.053 0.0 HOH
 3.593
 CA
 O
GLY B:150 B:2173 4.0 0.053 H 45.8 -142.5 4.0 0.053 0.0 HOH
 3.686
 CA
 O
GLY C:150 C:3173 4.0 0.053 H 46.6 -140.9 4.0 0.053 0.0 HOH
 6.852
 O
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:151 A:173 3.0 0.04 H 54.3 -137.4 3.0 0.04 0.0 HOH
 3.110
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:173 A:173 1.0 0.013 H 50.1 -132.6
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:174 A:174 8.0 0.107 H 52.7 -136.8