Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857498 . G A CCDS32450.1:NM_001025195.1:c.503aCc>aTc_NP_001020366.1:p.168T>I Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 THR A:149 A:1167 0.0 0.0 E -111.7 123.5 0.0 0.0 0.0 HOH
 2.925
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -113.3 125.1 0.0 0.0 0.0 HOH
 3.052
 OG1
 O
THR C:149 C:3167 0.0 0.0 E -107.2 126.0 0.0 0.0 0.0 HOH
 2.960
 OG1
 O
THR D:149 D:4167 0.0 0.0 E -110.9 126.3 0.0 0.0 0.0 HOH
 3.055
 OG1
 O
THR E:149 E:5167 0.0 0.0 E -106.3 124.9 0.0 0.0 0.0 HOH
 3.128
 OG1
 O
THR F:149 F:6167 0.0 0.0 E -110.7 121.5 0.0 0.0 0.0 HOH
 2.978
 OG1
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:149 A:1167 0.0 0.0 E -101.4 129.8 0.0 0.0 0.0 HOH
 2.505
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -112.8 123.9 0.0 0.0 0.0 SIA
HOH
 9.598
3.008
 O
OG1
 O1A
O
THR C:149 C:3167 0.0 0.0 E -105.9 124.6 0.0 0.0 0.0 HOH
 2.633
 OG1
 O
THR D:149 D:4167 0.0 0.0 E -106.2 122.1 NA NA NA
THR E:149 E:5167 0.0 0.0 E -108.8 128.9 NA NA NA
THR F:149 F:6167 0.0 0.0 E -100.7 131.8 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 THR A:149 A:1167 0.0 0.0 E -115.4 129.9 0.0 0.0 0.0 HOH
 3.107
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -113.8 126.2 0.0 0.0 0.0 HOH
 2.796
 OG1
 O
THR C:149 C:3167 0.0 0.0 E -113.8 125.5 0.0 0.0 0.0 HOH
 4.275
 CB
 O
THR D:149 D:4167 0.0 0.0 E -105.7 128.8 0.0 0.0 0.0 HOH
 2.905
 OG1
 O
THR E:149 E:5167 0.0 0.0 E -108.3 123.5 0.0 0.0 0.0 HOH
 2.993
 OG1
 O
THR F:149 F:6167 0.0 0.0 E -99.3 122.6 0.0 0.0 0.0 HOH
 2.649
 OG1
 O
THR G:149 G:1167 0.0 0.0 E -76.6 131.8 NA NA NA
THR H:149 H:2167 0.0 0.0 E -111.0 130.3 NA NA NA
THR I:149 I:3167 0.0 0.0 E -114.9 125.5 NA NA NA
THR J:149 J:4167 0.0 0.0 E -101.9 123.4 NA NA NA
THR K:149 K:5167 0.0 0.0 E -89.6 104.3 NA NA NA
THR L:149 L:6167 0.0 0.0 E -109.5 118.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:149 A:1167 0.0 0.0 E -106.0 115.7 0.0 0.0 0.0 HOH
 2.759
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -106.0 115.4 0.0 0.0 0.0 HOH
 2.713
 OG1
 O
THR C:149 C:3167 0.0 0.0 E -106.0 115.2 0.0 0.0 0.0 HOH
 3.041
 OG1
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:149 A:1167 0.0 0.0 E -107.2 125.5 0.0 0.0 0.0 HOH
 2.814
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -111.7 126.1 0.0 0.0 0.0 HOH
 2.710
 OG1
 O
THR C:149 C:3167 0.0 0.0 E -101.4 126.0 0.0 0.0 0.0 HOH
 3.128
 OG1
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:149 A:1167 0.0 0.0 E -112.1 109.3 0.0 0.0 0.0 HOH
 2.712
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -112.5 108.8 0.0 0.0 0.0 HOH
 3.004
 OG1
 O
THR C:149 C:3167 0.0 0.0 E -110.3 110.2 0.0 0.0 0.0 HOH
 2.835
 OG1
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 THR A:149 A:1167 0.0 0.0 E -107.5 125.3 0.0 0.0 0.0 HOH
 2.977
 OG1
 O
THR B:149 B:2167 0.0 0.0 E -105.9 129.4 0.0 0.0 0.0 HOH
 2.811
 OG1
 O
THR C:149 C:3167 0.0 0.0 E -108.4 124.3 0.0 0.0 0.0 HOH
 2.889
 OG1
 O
THR D:149 D:4167 0.0 0.0 E -113.2 126.8 0.0 0.0 0.0 HOH
 2.836
 OG1
 O
THR E:149 E:5167 0.0 0.0 E -109.8 124.3 0.0 0.0 0.0 HOH
 2.945
 OG1
 O
THR F:149 F:6167 0.0 0.0 E -109.6 126.6 0.0 0.0 0.0 HOH
 2.868
 OG1
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:147 A:167 0.0 0.0 E -116.8 123.8 0.0 0.0 0.0 HOH
 2.590
 OG1
 O
THR B:147 B:167 0.0 0.0 E -111.2 124.6 0.0 0.0 0.0 HOH
 2.533
 OG1
 O
THR C:147 C:167 0.0 0.0 E -108.0 120.0 0.0 0.0 0.0 HOH
 2.820
 OG1
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:147 A:167 0.0 0.0 E -107.2 130.1 0.0 0.0 0.0 HOH
 2.632
 OG1
 O
THR B:147 B:167 0.0 0.0 E -105.1 123.1 0.0 0.0 0.0 HOH
 2.781
 OG1
 O
THR C:147 C:167 0.0 0.0 E -105.6 121.5 0.0 0.0 0.0 HOH
 2.686
 OG1
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:147 A:167 0.0 0.0 E -100.7 117.1 0.0 0.0 0.0 HOH
 2.991
 OG1
 O
THR B:147 B:167 0.0 0.0 E -102.2 121.5 0.0 0.0 0.0 HOH
 2.553
 OG1
 O
THR C:147 C:167 0.0 0.0 E -104.7 122.1 0.0 0.0 0.0 HOH
 2.757
 OG1
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 THR A:147 A:167 0.0 0.0 E -98.8 127.3 0.0 0.0 0.0 HOH
 7.729
 OG1
 O
THR B:147 B:167 0.0 0.0 E -115.7 123.4 0.0 0.0 0.0 HOH
 4.469
 CB
 O
THR C:147 C:167 0.0 0.0 E -129.9 100.4 0.0 0.0 0.0 HOH
 3.100
 OG1
 O
THR D:147 D:167 0.0 0.0 E -104.4 121.5 NA NA NA
THR E:147 E:167 0.0 0.0 E -131.3 124.1 NA NA NA
THR F:147 F:167 0.0 0.0 E -122.2 96.1 NA NA NA
THR G:147 G:167 0.0 0.0 E -97.7 121.1 NA NA NA
THR H:147 H:167 0.0 0.0 E -112.0 117.0 NA NA NA
THR I:147 I:167 0.0 0.0 E -112.2 122.4 NA NA NA
THR J:147 J:167 0.0 0.0 E -102.1 112.5 NA NA NA
THR K:147 K:167 0.0 0.0 E -108.5 115.9 NA NA NA
THR L:147 L:167 0.0 0.0 E -106.1 132.4 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:147 A:1167 0.0 0.0 E -102.0 127.8 0.0 0.0 0.0 HOH
 2.855
 OG1
 O
THR B:147 B:2167 0.0 0.0 E -99.5 132.7 0.0 0.0 0.0 HOH
 2.958
 OG1
 O
THR C:147 C:3167 0.0 0.0 E -99.4 125.3 0.0 0.0 0.0 HOH
 2.907
 OG1
 O
THR D:147 D:4167 0.0 0.0 E -98.9 129.0 NA NA NA
THR E:147 E:5167 0.0 0.0 E -102.7 128.2 NA NA NA
THR F:147 F:6167 0.0 0.0 E -104.8 125.8 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 THR A:147 A:1167 0.0 0.0 E -99.9 130.2 0.0 0.0 0.0 HOH
 2.881
 OG1
 O
THR B:147 B:2167 0.0 0.0 E -102.3 122.8 0.0 0.0 0.0 HOH
 2.766
 OG1
 O
THR C:147 C:3167 0.0 0.0 E -100.3 127.7 0.0 0.0 0.0 HOH
 2.761
 OG1
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 THR A:147 A:167 0.0 0.0 E -103.0 126.7 0.0 0.0 0.0 HOH
 2.910
 OG1
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 THR A:147 A:167 0.0 0.0 E -104.7 130.6 0.0 0.0 0.0 HOH
 2.814
 OG1
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:147 A:167 0.0 0.0 E -107.1 131.1 0.0 0.0 0.0 HOH
 2.773
 OG1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 THR A:146 A:167 0.0 0.0 E -105.0 135.5 0.0 0.0 0.0 IOD
HOH
 9.693
2.955
 OG1
OG1
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 THR A:144 A:1167 0.0 0.0 E -110.0 115.4 0.0 0.0 0.0 HOH
 4.047
 C
 O
THR B:144 B:2167 0.0 0.0 E -111.4 115.2 0.0 0.0 0.0 HOH
 2.948
 OG1
 O
THR C:144 C:3167 0.0 0.0 E -111.3 114.8 0.0 0.0 0.0 HOH
 2.825
 OG1
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 THR A:145 A:167 1.0 0.007 E -103.3 122.0 1.0 0.007 0.0 HOH
 2.738
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 THR A:167 A:167 0.0 0.0 E -106.8 124.7
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 THR A:168 A:168 2.0 0.014 E -109.3 125.8