Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857525 . G A CCDS32450.1:NM_001025195.1:c.476gCt>gTt_NP_001020366.1:p.159A>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ALA A:140 A:1158 0.0 0.0 H -60.5 -54.2 0.0 0.0 0.0 HOH
 4.860
 O
 O
ALA B:140 B:2158 0.0 0.0 H -61.9 -49.3 0.0 0.0 0.0 HOH
 4.863
 N
 O
ALA C:140 C:3158 0.0 0.0 H -60.2 -51.9 0.0 0.0 0.0 HOH
 4.970
 N
 O
ALA D:140 D:4158 0.0 0.0 H -60.5 -52.1 0.0 0.0 0.0 HOH
 4.890
 N
 O
ALA E:140 E:5158 0.0 0.0 H -58.9 -50.3 0.0 0.0 0.0 HOH
 4.694
 O
 O
ALA F:140 F:6158 0.0 0.0 H -62.8 -52.8 0.0 0.0 0.0 HOH
 4.904
 N
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:140 A:1158 0.0 0.0 H -65.6 -50.8 0.0 0.0 0.0 HOH
 5.139
 N
 O
ALA B:140 B:2158 0.0 0.0 H -61.6 -58.1 0.0 0.0 0.0 HOH
 4.521
 O
 O
ALA C:140 C:3158 0.0 0.0 H -57.7 -58.0 0.0 0.0 0.0 HOH
 4.873
 N
 O
ALA D:140 D:4158 0.0 0.0 H -68.1 -40.2 NA NA NA
ALA E:140 E:5158 0.0 0.0 H -63.6 -55.6 NA NA NA
ALA F:140 F:6158 0.0 0.0 H -63.9 -55.8 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:140 A:1158 0.0 0.0 H -67.6 -53.5 0.0 0.0 0.0 HOH
 8.237
 O
 O
ALA B:140 B:2158 0.0 0.0 H -48.2 -51.6 0.0 0.0 0.0 HOH
 5.150
 N
 O
ALA C:140 C:3158 0.0 0.0 H -56.8 -52.3 0.0 0.0 0.0 HOH
 4.263
 O
 O
ALA D:140 D:4158 0.0 0.0 H -52.3 -61.8 0.0 0.0 0.0 HOH
 8.714
 O
 O
ALA E:140 E:5158 0.0 0.0 H -54.7 -40.1 0.0 0.0 0.0 HOH
 4.701
 N
 O
ALA F:140 F:6158 0.0 0.0 H -60.3 -48.3 0.0 0.0 0.0 HOH
 5.331
 N
 O
ALA G:140 G:1158 0.0 0.0 H -57.4 -57.1 NA NA NA
ALA H:140 H:2158 0.0 0.0 H -47.1 -45.4 NA NA NA
ALA I:140 I:3158 0.0 0.0 H -49.3 -49.7 NA NA NA
ALA J:140 J:4158 0.0 0.0 H -65.3 -45.8 NA NA NA
ALA K:140 K:5158 0.0 0.0 H -62.1 -58.4 NA NA NA
ALA L:140 L:6158 0.0 0.0 H -66.0 -50.6 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:140 A:1158 0.0 0.0 H -59.0 -44.8 0.0 0.0 0.0 HOH
 5.328
 O
 O
ALA B:140 B:2158 0.0 0.0 H -59.5 -45.6 0.0 0.0 0.0 HOH
 3.899
 O
 O
ALA C:140 C:3158 0.0 0.0 H -60.8 -45.2 0.0 0.0 0.0 HOH
 4.882
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:140 A:1158 0.0 0.0 H -61.6 -50.9 0.0 0.0 0.0 HOH
 4.749
 N
 O
ALA B:140 B:2158 0.0 0.0 H -65.7 -36.3 0.0 0.0 0.0 SO4
HOH
 9.098
3.661
 O
O
 O1
O
ALA C:140 C:3158 0.0 0.0 H -58.7 -41.9 0.0 0.0 0.0 HOH
 4.689
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:140 A:1158 0.0 0.0 H -57.0 -50.5 0.0 0.0 0.0 HOH
 5.614
 O
 O
ALA B:140 B:2158 0.0 0.0 H -56.7 -49.1 0.0 0.0 0.0 HOH
 4.817
 N
 O
ALA C:140 C:3158 0.0 0.0 H -58.6 -50.2 0.0 0.0 0.0 HOH
 4.659
 N
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:140 A:1158 0.0 0.0 H -60.5 -52.6 0.0 0.0 0.0 HOH
 4.427
 O
 O
ALA B:140 B:2158 0.0 0.0 H -56.9 -47.2 0.0 0.0 0.0 HOH
 4.427
 O
 O
ALA C:140 C:3158 0.0 0.0 H -58.6 -58.0 0.0 0.0 0.0 HOH
 4.584
 O
 O
ALA D:140 D:4158 0.0 0.0 H -60.9 -44.3 0.0 0.0 0.0 HOH
 4.938
 N
 O
ALA E:140 E:5158 0.0 0.0 H -59.8 -47.9 0.0 0.0 0.0 HOH
 4.965
 N
 O
ALA F:140 F:6158 0.0 0.0 H -56.6 -53.4 0.0 0.0 0.0 HOH
 4.731
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:138 A:158 0.0 0.0 H -61.5 -50.9 0.0 0.0 0.0 HOH
 8.635
 O
 O
ALA B:138 B:158 0.0 0.0 H -61.4 -52.6 0.0 0.0 0.0 HOH
 4.512
 N
 O
ALA C:138 C:158 0.0 0.0 H -54.3 -47.1 0.0 0.0 0.0 HOH
 7.633
 C
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:138 A:158 0.0 0.0 H -64.8 -47.6 0.0 0.0 0.0 HOH
 5.289
 N
 O
ALA B:138 B:158 0.0 0.0 H -59.9 -51.2 0.0 0.0 0.0 HOH
 4.524
 O
 O
ALA C:138 C:158 0.0 0.0 H -63.2 -48.4 0.0 0.0 0.0 HOH
 8.903
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:138 A:158 0.0 0.0 H -63.2 -46.7 0.0 0.0 0.0 HOH
 5.000
 N
 O
ALA B:138 B:158 0.0 0.0 H -57.1 -52.9 0.0 0.0 0.0 HOH
 5.074
 N
 O
ALA C:138 C:158 0.0 0.0 H -61.9 -52.3 0.0 0.0 0.0 HOH
 4.651
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:138 A:158 0.0 0.0 H -55.7 -66.8 0.0 0.0 0.0 HOH
 7.614
 O
 O
ALA B:138 B:158 0.0 0.0 H -73.7 -65.1 0.0 0.0 0.0 HOH
 8.577
 O
 O
ALA C:138 C:158 0.0 0.0 H -49.1 -38.3 0.0 0.0 0.0
ALA D:138 D:158 0.0 0.0 H -54.5 -60.7 NA NA NA
ALA E:138 E:158 0.0 0.0 H -65.5 -59.6 NA NA NA
ALA F:138 F:158 0.0 0.0 H -43.0 -40.7 NA NA NA
ALA G:138 G:158 0.0 0.0 H -76.6 -34.4 NA NA NA
ALA H:138 H:158 0.0 0.0 H -61.2 -55.0 NA NA NA
ALA I:138 I:158 0.0 0.0 H -57.3 -62.0 NA NA NA
ALA J:138 J:158 0.0 0.0 H -55.5 -52.1 NA NA NA
ALA K:138 K:158 0.0 0.0 H -62.7 -64.7 NA NA NA
ALA L:138 L:158 0.0 0.0 H -58.9 -68.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:138 A:1158 0.0 0.0 H -63.5 -47.7 0.0 0.0 0.0 HOH
 4.476
 O
 O
ALA B:138 B:2158 0.0 0.0 H -55.0 -50.2 0.0 0.0 0.0 HOH
 4.933
 N
 O
ALA C:138 C:3158 0.0 0.0 H -65.8 -57.1 0.0 0.0 0.0 HOH
 4.998
 N
 O
ALA D:138 D:4158 0.0 0.0 H -65.6 -50.7 NA NA NA
ALA E:138 E:5158 0.0 0.0 H -56.4 -51.0 NA NA NA
ALA F:138 F:6158 0.0 0.0 H -59.6 -55.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:138 A:1158 0.0 0.0 H -59.8 -51.4 0.0 0.0 0.0 HOH
 4.472
 O
 O
ALA B:138 B:2158 0.0 0.0 H -55.7 -60.0 0.0 0.0 0.0 HOH
 4.016
 O
 O
ALA C:138 C:3158 0.0 0.0 H -59.4 -58.7 0.0 0.0 0.0 HOH
 4.366
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ALA A:138 A:158 0.0 0.0 H -57.8 -47.7 0.0 0.0 0.0 HOH
 4.423
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ALA A:138 A:158 0.0 0.0 H -62.2 -47.2 0.0 0.0 0.0 HOH
 4.294
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:138 A:158 0.0 0.0 H -60.3 -45.4 0.0 0.0 0.0 HOH
 4.610
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:137 A:158 0.0 0.0 H -59.0 -47.0 0.0 0.0 0.0 IOD
HOH
 9.401
4.512
 CB
O
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ALA A:135 A:1158 0.0 0.0 H -57.7 -55.1 0.0 0.0 0.0
ALA B:135 B:2158 0.0 0.0 H -58.5 -55.1 0.0 0.0 0.0 HOH
 5.495
 N
 O
ALA C:135 C:3158 0.0 0.0 H -58.6 -54.6 0.0 0.0 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 SER A:136 A:158 0.0 0.0 H -66.9 -41.0 0.0 0.0 0.0 HOH
 7.242
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ALA A:158 A:158 0.0 0.0 H -61.3 -50.2
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ALA A:159 A:159 0.0 0.0 H -60.2 -49.4