Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857555 . G A CCDS32450.1:NM_001025195.1:c.446gCg>gTg_NP_001020366.1:p.149A>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ALA A:130 A:1148 1.0 0.009 -156.3 158.9 1.0 0.009 0.0 THA
HOH
 9.299
3.243
 N
N
 C6
O
ALA B:130 B:2148 1.0 0.009 -158.8 153.5 1.0 0.009 0.0 THA
HOH
 9.710
3.337
 N
N
 C13
O
ALA C:130 C:3148 1.0 0.009 -163.8 153.1 1.0 0.009 0.0 THA
HOH
 9.760
3.487
 N
N
 C1
O
ALA D:130 D:4148 1.0 0.009 -157.7 153.0 1.0 0.009 0.0 THA
HOH
 9.459
3.255
 N
N
 C13
O
ALA E:130 E:5148 2.0 0.017 -160.8 156.0 2.0 0.017 0.0 THA
HOH
 9.507
3.045
 N
N
 C13
O
ALA F:130 F:6148 2.0 0.017 -157.7 154.4 2.0 0.017 0.0 THA
HOH
 9.439
3.349
 N
N
 C1
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:130 A:1148 1.0 0.009 -165.8 163.6 1.0 0.009 0.0 HTQ
HOH
 9.171
3.245
 N
N
 O20
O
ALA B:130 B:2148 0.0 0.0 -163.9 156.2 0.0 0.0 0.0 HTQ
HOH
 8.708
3.239
 N
N
 O20
O
ALA C:130 C:3148 2.0 0.017 -153.9 158.5 2.0 0.017 0.0 HTQ
HOH
 9.254
3.171
 N
N
 C15
O
ALA D:130 D:4148 1.0 0.009 -164.2 151.9 NA NA NA
ALA E:130 E:5148 1.0 0.009 -150.2 166.0 NA NA NA
ALA F:130 F:6148 1.0 0.009 -165.0 159.1 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:130 A:1148 0.0 0.0 -147.6 160.2 0.0 0.0 0.0 NLX
HOH
 9.999
3.210
 N
CA
 C16
O
ALA B:130 B:2148 2.0 0.017 -146.2 168.2 2.0 0.017 0.0 NLX
HOH
 9.063
2.878
 N
N
 O1
O
ALA C:130 C:3148 4.0 0.035 -150.1 160.7 4.0 0.035 0.0 HOH
 3.043
 N
 O
ALA D:130 D:4148 2.0 0.017 -144.8 160.2 2.0 0.017 0.0 NLX
HOH
 9.975
2.814
 N
N
 O1
O
ALA E:130 E:5148 2.0 0.017 -160.2 145.8 2.0 0.017 0.0 NLX
HOH
 9.134
3.865
 N
CA
 C7
O
ALA F:130 F:6148 1.0 0.009 -157.1 157.1 1.0 0.009 0.0 NLX
HOH
 9.248
2.815
 N
N
 C19
O
ALA G:130 G:1148 1.0 0.009 -163.6 147.8 NA NA NA
ALA H:130 H:2148 2.0 0.017 -169.9 146.8 NA NA NA
ALA I:130 I:3148 2.0 0.017 -145.6 160.8 NA NA NA
ALA J:130 J:4148 2.0 0.017 -159.2 144.0 NA NA NA
ALA K:130 K:5148 2.0 0.017 -151.9 154.0 NA NA NA
ALA L:130 L:6148 1.0 0.009 -167.3 153.6 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:130 A:1148 1.0 0.009 -158.8 156.2 1.0 0.009 0.0 HOH
 3.540
 N
 O
ALA B:130 B:2148 2.0 0.017 -158.9 155.1 2.0 0.017 0.0 HOH
 3.555
 N
 O
ALA C:130 C:3148 1.0 0.009 -166.8 155.0 1.0 0.009 0.0 HOH
 3.496
 N
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:130 A:1148 2.0 0.017 -151.6 169.2 2.0 0.017 0.0 F
PLM
HOH
 9.904
9.866
3.174
 N
N
N
 F
C7
O
ALA B:130 B:2148 0.0 0.0 -167.5 169.5 0.0 0.0 0.0 HOH
 3.437
 N
 O
ALA C:130 C:3148 1.0 0.009 -172.4 160.3 1.0 0.009 0.0 F
HOH
 9.896
3.405
 N
N
 F
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:130 A:1148 2.0 0.017 -168.8 158.2 2.0 0.017 0.0 TCH
HOH
 8.662
3.746
 N
CA
 C21
O
ALA B:130 B:2148 2.0 0.017 -170.5 158.0 2.0 0.017 0.0 TCH
HOH
 9.322
3.905
 N
CB
 C21
O
ALA C:130 C:3148 2.0 0.017 -168.6 157.6 2.0 0.017 0.0 TCH
HOH
 9.730
3.519
 N
N
 C21
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:130 A:1148 1.0 0.009 -159.0 154.7 1.0 0.009 0.0 COA
HOH
 8.442
3.288
 N
N
 O9P
O
ALA B:130 B:2148 2.0 0.017 -162.3 150.4 2.0 0.017 0.0 COA
HOH
 8.418
3.212
 N
N
 O9P
O
ALA C:130 C:3148 1.0 0.009 -164.3 156.3 1.0 0.009 0.0 COA
HOH
 8.682
3.241
 N
N
 O9P
O
ALA D:130 D:4148 1.0 0.009 -162.1 154.2 1.0 0.009 0.0 COA
HOH
 8.380
3.175
 N
N
 O9P
O
ALA E:130 E:5148 1.0 0.009 -160.7 156.0 1.0 0.009 0.0 COA
HOH
 8.425
3.131
 N
N
 O9P
O
ALA F:130 F:6148 2.0 0.017 -158.4 153.0 2.0 0.017 0.0 COA
HOH
 8.520
3.294
 N
N
 O9P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:128 A:148 1.0 0.009 -160.2 165.9 1.0 0.009 0.0 CTX
HOH
 9.830
3.376
 N
N
 C10
O
ALA B:128 B:148 2.0 0.017 -173.1 152.7 2.0 0.017 0.0 CTX
HOH
 9.743
4.016
 N
CB
 C10
O
ALA C:128 C:148 2.0 0.017 -165.4 150.4 2.0 0.017 0.0 CTX
HOH
 9.739
6.595
 N
O
 C10
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:128 A:148 1.0 0.009 -157.3 158.6 1.0 0.009 0.0 HOH
 3.644
 N
 O
ALA B:128 B:148 2.0 0.017 -157.2 165.0 2.0 0.017 0.0 HOH
 3.483
 CA
 O
ALA C:128 C:148 2.0 0.017 -154.0 157.8 2.0 0.017 0.0 SMB
HOH
 9.804
3.238
 N
N
 O2
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:128 A:148 1.0 0.009 -162.8 153.7 1.0 0.009 0.0 HOH
 3.400
 N
 O
ALA B:128 B:148 0.0 0.0 -158.7 157.2 0.0 0.0 0.0 HOH
 3.411
 N
 O
ALA C:128 C:148 0.0 0.0 -162.3 157.6 0.0 0.0 0.0 HOH
 3.039
 N
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:128 A:148 2.0 0.017 -162.4 169.6 2.0 0.017 0.0 HOH
 4.645
 CA
 O
ALA B:128 B:148 2.0 0.017 -157.8 -177.3 2.0 0.017 0.0 HOH
 3.869
 CA
 O
ALA C:128 C:148 2.0 0.017 173.3 141.3 2.0 0.017 0.0 BEZ
HOH
 9.678
3.376
 N
N
 O2
O
ALA D:128 D:148 1.0 0.009 -169.8 177.7 NA NA NA
ALA E:128 E:148 3.0 0.026 -151.9 168.7 NA NA NA
ALA F:128 F:148 1.0 0.009 -152.1 145.7 NA NA NA
ALA G:128 G:148 1.0 0.009 -133.9 146.4 NA NA NA
ALA H:128 H:148 4.0 0.035 -167.8 149.2 NA NA NA
ALA I:128 I:148 2.0 0.017 -159.4 156.3 NA NA NA
ALA J:128 J:148 2.0 0.017 -143.5 162.8 NA NA NA
ALA K:128 K:148 2.0 0.017 -164.7 166.0 NA NA NA
ALA L:128 L:148 3.0 0.026 -156.0 -176.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:128 A:1148 2.0 0.017 -161.9 161.1 2.0 0.017 0.0 GD7
HOH
 9.598
3.105
 N
N
 O11
O
ALA B:128 B:2148 2.0 0.017 -162.2 158.3 2.0 0.017 0.0 GD7
HOH
 9.741
3.178
 N
N
 O11
O
ALA C:128 C:3148 1.0 0.009 -167.1 156.5 1.0 0.009 0.0 GD7
HOH
 9.722
3.286
 N
N
 O11
O
ALA D:128 D:4148 1.0 0.009 -159.3 163.9 NA NA NA
ALA E:128 E:5148 1.0 0.009 -167.3 155.8 NA NA NA
ALA F:128 F:6148 1.0 0.009 -164.9 164.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:128 A:1148 2.0 0.017 -158.4 150.0 2.0 0.017 0.0 NTJ
HOH
 9.262
3.186
 N
N
 C2
O
ALA B:128 B:2148 2.0 0.017 -168.0 162.4 2.0 0.017 0.0 NTJ
HOH
 9.542
3.239
 N
N
 C2
O
ALA C:128 C:3148 1.0 0.009 -172.1 159.4 1.0 0.009 0.0 NTJ
HOH
 9.152
3.423
 N
N
 C2
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ALA A:128 A:148 2.0 0.017 -156.5 156.2 2.0 0.017 0.0 HOH
 3.109
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ALA A:128 A:148 1.0 0.009 -154.6 149.0 1.0 0.009 0.0 HOH
 3.185
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:128 A:148 2.0 0.017 -157.3 150.5 2.0 0.017 0.0 HOH
 3.199
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:127 A:148 2.0 0.017 -153.3 153.2 2.0 0.017 0.0 IOD
IOD
HOH
 5.254
6.579
3.165
 CB
CB
N
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ALA A:125 A:1148 2.0 0.017 -164.5 150.5 2.0 0.017 0.0 WW2
HOH
 9.622
5.166
 N
CB
 C7
O
ALA B:125 B:2148 2.0 0.017 -165.9 150.7 2.0 0.017 0.0 WW2
HOH
 9.544
3.871
 N
CA
 O1
O
ALA C:125 C:3148 2.0 0.017 -165.5 151.0 2.0 0.017 0.0 WW2
HOH
 9.560
3.945
 N
CB
 O1
O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:126 A:148 1.0 0.013 -164.6 162.6 1.0 0.013 0.0 HOH
 2.826
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ALA A:148 A:148 2.0 0.017 -153.9 152.3
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ALA A:149 A:149 2.0 0.017 -154.4 145.4