Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857559 . C A CCDS32450.1:NM_001025195.1:c.442Ggt>Tgt_NP_001020366.1:p.148G>C Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:129 A:1147 6.0 0.08 115.5 163.8 6.0 0.08 0.0 THA
HOH
 7.337
2.803
 N
O
 C13
O
GLY B:129 B:2147 7.0 0.093 116.3 165.6 7.0 0.093 0.0 THA
HOH
 7.627
2.973
 N
O
 C13
O
GLY C:129 C:3147 7.0 0.093 120.8 170.0 7.0 0.093 0.0 THA
HOH
 7.585
2.877
 N
O
 C6
O
GLY D:129 D:4147 7.0 0.093 115.6 163.6 7.0 0.093 0.0 THA
HOH
 7.669
2.741
 N
O
 C13
O
GLY E:129 E:5147 6.0 0.08 116.9 165.0 6.0 0.08 0.0 THA
HOH
 7.121
2.880
 N
O
 C12
O
GLY F:129 F:6147 8.0 0.107 118.5 162.9 8.0 0.107 0.0 THA
HOH
 7.214
2.942
 N
O
 C13
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:129 A:1147 6.0 0.08 112.0 173.9 6.0 0.08 0.0 CL
HTQ
HOH
 8.661
6.470
2.979
 CA
N
O
 CL
C15
O
GLY B:129 B:2147 7.0 0.093 122.1 166.5 7.0 0.093 0.0 HTQ
HOH
 6.650
3.055
 N
O
 C15
O
GLY C:129 C:3147 7.0 0.093 120.5 163.5 7.0 0.093 0.0 HTQ
HOH
 6.298
2.967
 N
O
 C15
O
GLY D:129 D:4147 6.0 0.08 124.7 167.9 NA NA NA
GLY E:129 E:5147 5.0 0.067 113.6 164.8 NA NA NA
GLY F:129 F:6147 7.0 0.093 125.6 172.3 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:129 A:1147 5.0 0.067 102.6 153.6 5.0 0.067 0.0 NLX
HOH
 6.773
2.578
 N
O
 C16
O
GLY B:129 B:2147 8.0 0.107 108.6 159.2 8.0 0.107 0.0 NLX
HOH
 7.245
3.031
 CA
O
 O1
O
GLY C:129 C:3147 8.0 0.107 150.3 160.2 8.0 0.107 0.0 NLX
HOH
 8.493
3.812
 CA
C
 O1
O
GLY D:129 D:4147 7.0 0.093 117.7 153.2 7.0 0.093 0.0 NLX
HOH
 7.396
2.992
 N
O
 C16
O
GLY E:129 E:5147 7.0 0.093 130.5 166.2 7.0 0.093 0.0 NLX
HOH
 7.143
2.937
 N
O
 C8
O
GLY F:129 F:6147 6.0 0.08 111.7 161.4 6.0 0.08 0.0 NLX
HOH
 6.735
3.012
 N
CA
 C19
O
GLY G:129 G:1147 6.0 0.08 134.7 168.3 NA NA NA
GLY H:129 H:2147 9.0 0.12 124.0 172.4 NA NA NA
GLY I:129 I:3147 9.0 0.12 116.0 156.0 NA NA NA
GLY J:129 J:4147 5.0 0.067 116.0 156.6 NA NA NA
GLY K:129 K:5147 5.0 0.067 113.2 160.7 NA NA NA
GLY L:129 L:6147 5.0 0.067 118.6 171.1 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:129 A:1147 8.0 0.107 122.8 162.0 8.0 0.107 0.0 PLM
HOH
 7.429
3.233
 N
CA
 C7
O
GLY B:129 B:2147 8.0 0.107 133.6 161.8 8.0 0.107 0.0 PLM
HOH
 7.574
2.518
 N
O
 C6
O
GLY C:129 C:3147 8.0 0.107 122.6 170.1 8.0 0.107 0.0 PLM
HOH
 7.622
3.397
 N
CA
 C7
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:129 A:1147 9.0 0.12 121.5 162.1 9.0 0.12 0.0 F
PLM
HOH
 8.139
6.998
2.964
 CA
N
CA
 F
C7
O
GLY B:129 B:2147 8.0 0.107 125.6 175.1 8.0 0.107 0.0 F
PLM
HOH
 8.573
7.183
2.823
 CA
N
O
 F
C7
O
GLY C:129 C:3147 8.0 0.107 130.2 174.5 8.0 0.107 0.0 F
COA
HOH
 8.268
8.510
2.905
 CA
N
O
 F
O5P
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:129 A:1147 8.0 0.107 134.6 176.6 8.0 0.107 0.0 TCH
HOH
 5.883
2.930
 N
O
 C21
O
GLY B:129 B:2147 8.0 0.107 133.6 177.9 8.0 0.107 0.0 TCH
HOH
 6.940
4.331
 N
O
 C21
O
GLY C:129 C:3147 8.0 0.107 133.1 177.0 8.0 0.107 0.0 TCH
HOH
 6.905
3.047
 N
CA
 C21
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:129 A:1147 5.0 0.067 114.6 166.1 5.0 0.067 0.0 COA
HOH
 5.537
2.917
 N
O
 O9P
O
GLY B:129 B:2147 7.0 0.093 120.6 168.3 7.0 0.093 0.0 COA
HOH
 5.645
2.961
 N
O
 O9P
O
GLY C:129 C:3147 7.0 0.093 118.4 168.2 7.0 0.093 0.0 COA
HOH
 5.791
2.959
 N
O
 O9P
O
GLY D:129 D:4147 7.0 0.093 116.0 169.1 7.0 0.093 0.0 COA
HOH
 5.571
2.804
 N
O
 O9P
O
GLY E:129 E:5147 5.0 0.067 114.3 164.3 5.0 0.067 0.0 COA
HOH
 5.562
2.826
 N
O
 O9P
O
GLY F:129 F:6147 6.0 0.08 120.9 164.2 6.0 0.08 0.0 COA
HOH
 5.745
2.894
 N
O
 O9P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:127 A:147 7.0 0.093 111.2 167.0 7.0 0.093 0.0 CTX
HOH
 7.579
2.752
 N
CA
 C6
O
GLY B:127 B:147 8.0 0.107 124.7 173.5 8.0 0.107 0.0 CTX
HOH
 7.652
4.330
 N
O
 C6
O
GLY C:127 C:147 8.0 0.107 128.8 172.0 8.0 0.107 0.0 CTX
HOH
 7.798
7.505
 N
N
 C5
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:127 A:147 10.0 0.133 129.6 163.6 10.0 0.133 0.0 SMB
HOH
 7.692
3.058
 N
O
 C2
O
GLY B:127 B:147 10.0 0.133 122.6 165.0 10.0 0.133 0.0 SMB
HOH
 8.041
2.672
 N
O
 C2
O
GLY C:127 C:147 10.0 0.133 112.9 160.4 10.0 0.133 0.0 SMB
HOH
 7.586
3.167
 N
O
 O2
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:127 A:147 8.0 0.107 126.9 164.6 8.0 0.107 0.0 EEE
HOH
 8.217
3.069
 N
CA
 C2
O
GLY B:127 B:147 8.0 0.107 125.2 162.9 8.0 0.107 0.0 EEE
HOH
 8.080
2.630
 N
O
 C2
O
GLY C:127 C:147 7.0 0.093 124.2 165.4 7.0 0.093 0.0 EEE
HOH
 7.766
3.085
 N
O
 C2
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:127 A:147 9.0 0.12 105.6 169.5 9.0 0.12 0.0 BEZ
HOH
 7.944
3.884
 N
O
 C4
O
GLY B:127 B:147 10.0 0.133 117.4 169.0 10.0 0.133 0.0 BEZ
HOH
 8.225
2.926
 N
O
 O1
O
GLY C:127 C:147 6.0 0.08 164.4 -169.2 6.0 0.08 0.0 BEZ
HOH
 8.043
3.313
 CA
O
 O2
O
GLY D:127 D:147 6.0 0.08 108.4 178.0 NA NA NA
GLY E:127 E:147 6.0 0.08 106.3 164.5 NA NA NA
GLY F:127 F:147 4.0 0.053 123.0 153.6 NA NA NA
GLY G:127 G:147 3.0 0.04 108.1 143.3 NA NA NA
GLY H:127 H:147 8.0 0.107 136.0 170.4 NA NA NA
GLY I:127 I:147 8.0 0.107 117.3 166.0 NA NA NA
GLY J:127 J:147 4.0 0.053 117.8 150.9 NA NA NA
GLY K:127 K:147 8.0 0.107 125.3 173.5 NA NA NA
GLY L:127 L:147 10.0 0.133 116.0 167.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:127 A:1147 8.0 0.107 120.9 164.2 8.0 0.107 0.0 GD7
HOH
 7.916
2.988
 CA
O
 O11
O
GLY B:127 B:2147 7.0 0.093 131.0 169.0 7.0 0.093 0.0 GD7
HOH
 8.054
2.937
 CA
O
 O11
O
GLY C:127 C:3147 7.0 0.093 120.9 169.5 7.0 0.093 0.0 GD7
HOH
 8.064
2.896
 CA
O
 O11
O
GLY D:127 D:4147 8.0 0.107 115.6 163.9 NA NA NA
GLY E:127 E:5147 9.0 0.12 132.7 171.1 NA NA NA
GLY F:127 F:6147 8.0 0.107 120.8 171.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:127 A:1147 8.0 0.107 121.0 163.5 8.0 0.107 0.0 NTJ
HOH
 7.680
3.074
 CA
O
 C2
O
GLY B:127 B:2147 7.0 0.093 120.3 173.9 7.0 0.093 0.0 NTJ
HOH
 7.849
2.919
 CA
O
 C2
O
GLY C:127 C:3147 6.0 0.08 122.8 174.3 6.0 0.08 0.0 NTJ
HOH
 7.576
2.919
 CA
O
 C2
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:127 A:147 8.0 0.107 118.4 166.3 8.0 0.107 0.0 HOH
 2.997
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:127 A:147 6.0 0.08 119.3 166.9 6.0 0.08 0.0 HOH
 2.872
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:127 A:147 6.0 0.08 121.4 164.6 6.0 0.08 0.0 HOH
 2.888
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:126 A:147 7.0 0.093 123.4 165.6 7.0 0.093 0.0 IOD
IOD
HOH
 7.885
8.122
2.922
 C
C
O
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:124 A:1147 7.0 0.093 116.8 167.7 7.0 0.093 0.0 WW2
HOH
 7.431
6.377
 N
O
 C5
O
GLY B:124 B:2147 6.0 0.08 118.1 168.1 6.0 0.08 0.0 WW2
HOH
 7.818
3.275
 N
O
 O1
O
GLY C:124 C:3147 6.0 0.08 118.3 168.7 6.0 0.08 0.0 WW2
HOH
 7.671
6.440
 N
O
 O1
O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:125 A:147 7.0 0.093 121.9 168.7 7.0 0.093 0.0 HOH
 2.910
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:147 A:147 6.0 0.08 115.5 168.1
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:148 A:148 6.0 0.08 121.2 167.5