Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857570 . C A CCDS32450.1:NM_001025195.1:c.431gGg>gTg_NP_001020366.1:p.144G>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:125 A:1143 16.0 0.213 T 52.8 21.4 16.0 0.213 0.0 THA
HOH
 3.503
2.657
 N
N
 N7
O
GLY B:125 B:2143 14.0 0.187 T 58.9 20.7 14.0 0.187 0.0 THA
HOH
 3.731
2.635
 N
N
 N15
O
GLY C:125 C:3143 16.0 0.213 T 58.5 17.9 16.0 0.213 0.0 THA
HOH
 3.717
2.649
 N
N
 C2
O
GLY D:125 D:4143 19.0 0.253 T 56.7 16.4 19.0 0.253 0.0 THA
HOH
 3.566
2.528
 N
N
 N7
O
GLY E:125 E:5143 14.0 0.187 T 55.7 16.8 14.0 0.187 0.0 THA
HOH
 3.989
2.669
 N
N
 C10
O
GLY F:125 F:6143 16.0 0.213 T 59.5 16.1 16.0 0.213 0.0 THA
HOH
 3.680
2.590
 N
N
 C10
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:125 A:1143 14.0 0.187 T 62.9 18.0 14.0 0.187 0.0 CL
HTQ
HOH
 2.685
3.548
3.259
 N
CA
N
 CL
C4
O
GLY B:125 B:2143 11.0 0.147 T 62.7 12.2 11.0 0.147 0.0 HTQ
HOH
 3.525
2.672
 CA
N
 C4
O
GLY C:125 C:3143 18.0 0.24 T 53.7 18.5 18.0 0.24 0.0 HTQ
HOH
 3.363
2.635
 CA
N
 C4
O
GLY D:125 D:4143 12.0 0.16 T 55.8 16.8 NA NA NA
GLY E:125 E:5143 17.0 0.227 T 64.9 15.5 NA NA NA
GLY F:125 F:6143 14.0 0.187 T 64.1 14.1 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:125 A:1143 13.0 0.173 T 55.9 23.8 13.0 0.173 0.0 NLX
HOH
 3.024
3.549
 N
N
 O2
O
GLY B:125 B:2143 12.0 0.16 T 71.8 13.7 12.0 0.16 0.0 NLX
HOH
 3.278
2.554
 CA
N
 C16
O
GLY C:125 C:3143 11.0 0.147 T 61.7 23.3 11.0 0.147 0.0 NLX
HOH
 2.881
3.491
 N
O
 O2
O
GLY D:125 D:4143 15.0 0.2 T 54.0 29.4 15.0 0.2 0.0 NLX
HOH
 3.168
2.228
 N
N
 O2
O
GLY E:125 E:5143 11.0 0.147 B 70.6 6.0 11.0 0.147 0.0 NLX
HOH
 3.318
7.198
 N
N
 C8
O
GLY F:125 F:6143 8.0 0.107 T 87.0 16.1 8.0 0.107 0.0 NLX
HOH
 2.869
3.292
 N
N
 C8
O
GLY G:125 G:1143 11.0 0.147 T 48.1 33.8 NA NA NA
GLY H:125 H:2143 13.0 0.173 T 60.9 20.3 NA NA NA
GLY I:125 I:3143 10.0 0.133 T 66.1 14.6 NA NA NA
GLY J:125 J:4143 11.0 0.147 T 53.0 26.7 NA NA NA
GLY K:125 K:5143 14.0 0.187 T 70.1 24.8 NA NA NA
GLY L:125 L:6143 9.0 0.12 T 77.5 19.4 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:125 A:1143 27.0 0.36 T 53.2 26.2 27.0 0.36 0.0 PLM
HOH
 3.541
2.556
 N
N
 C6
O
GLY B:125 B:2143 13.0 0.173 T 53.7 26.9 13.0 0.173 0.0 PLM
HOH
 3.808
2.696
 CA
N
 O2
O
GLY C:125 C:3143 14.0 0.187 T 53.4 20.2 14.0 0.187 0.0 PLM
HOH
 4.037
2.454
 N
N
 C3
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:125 A:1143 22.0 0.293 T 49.5 22.0 22.0 0.293 0.0 F
PLM
HOH
 2.397
4.036
3.599
 N
N
N
 F
C5
O
GLY B:125 B:2143 16.0 0.213 T 59.3 21.3 16.0 0.213 0.0 F
PLM
HOH
 2.638
4.120
3.828
 N
N
N
 F
C5
O
GLY C:125 C:3143 13.0 0.173 T 59.1 18.4 13.0 0.173 0.0 F
COA
HOH
 2.693
3.923
3.635
 N
CA
N
 F
C2P
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:125 A:1143 24.0 0.32 T 58.5 16.5 24.0 0.32 0.0 TCH
HOH
 2.648
3.693
 N
N
 O12
O
GLY B:125 B:2143 23.0 0.307 T 59.3 17.1 23.0 0.307 0.0 TCH
HOH
 3.389
2.382
 N
N
 O12
O
GLY C:125 C:3143 24.0 0.32 T 58.5 16.8 24.0 0.32 0.0 TCH
HOH
 2.744
3.464
 N
N
 O12
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:125 A:1143 11.0 0.147 T 55.7 21.9 11.0 0.147 0.0 COA
HOH
 3.643
2.658
 N
N
 C5P
O
GLY B:125 B:2143 11.0 0.147 T 56.8 19.8 11.0 0.147 0.0 COA
HOH
 3.611
2.653
 N
N
 C5P
O
GLY C:125 C:3143 11.0 0.147 T 62.0 16.5 11.0 0.147 0.0 COA
HOH
 3.597
2.676
 N
N
 C3P
O
GLY D:125 D:4143 12.0 0.16 T 58.6 25.8 12.0 0.16 0.0 COA
HOH
 3.533
2.634
 CA
N
 C3P
O
GLY E:125 E:5143 11.0 0.147 T 63.0 15.4 11.0 0.147 0.0 COA
HOH
 3.754
2.719
 N
N
 C5P
O
GLY F:125 F:6143 11.0 0.147 T 55.2 19.0 11.0 0.147 0.0 COA
HOH
 3.456
2.626
 CA
N
 C3P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:123 A:143 17.0 0.227 T 52.5 28.6 17.0 0.227 0.0 CTX
HOH
 3.622
2.379
 N
N
 C9
O
GLY B:123 B:143 16.0 0.213 T 59.5 23.3 16.0 0.213 0.0 CTX
HOH
 3.766
2.607
 N
N
 C9
O
GLY C:123 C:143 17.0 0.227 T 50.1 17.9 17.0 0.227 0.0 CTX
HOH
 3.779
2.809
 N
N
 C9
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:123 A:143 29.0 0.387 T 52.6 26.9 29.0 0.387 0.0 SMB
HOH
 3.982
2.535
 N
N
 C3
O
GLY B:123 B:143 27.0 0.36 T 55.0 25.4 27.0 0.36 0.0 SMB
HOH
 3.681
2.612
 N
N
 C3
O
GLY C:123 C:143 22.0 0.293 T 48.9 18.9 22.0 0.293 0.0 SMB
HOH
 3.082
2.721
 N
N
 O2
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:123 A:143 22.0 0.293 T 51.9 20.8 22.0 0.293 0.0 EEE
HOH
 3.908
3.713
 CA
N
 C3
O
GLY B:123 B:143 20.0 0.267 T 52.8 19.3 20.0 0.267 0.0 EEE
HOH
 3.824
2.567
 N
N
 C2
O
GLY C:123 C:143 20.0 0.267 T 55.6 20.5 20.0 0.267 0.0 EEE
HOH
 3.756
2.569
 N
N
 C2
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:123 A:143 27.0 0.36 T 38.5 30.2 27.0 0.36 0.0 BEZ
HOH
 4.034
2.825
 N
N
 C1
O
GLY B:123 B:143 11.0 0.147 T 47.9 22.5 11.0 0.147 0.0 BEZ
HOH
 3.847
2.302
 N
N
 C
O
GLY C:123 C:143 13.0 0.173 T 77.8 12.7 13.0 0.173 0.0 BEZ
HOH
 2.533
3.750
 N
N
 O2
O
GLY D:123 D:143 20.0 0.267 T 54.0 18.0 NA NA NA
GLY E:123 E:143 16.0 0.213 T 60.0 23.9 NA NA NA
GLY F:123 F:143 9.0 0.12 T 57.9 19.7 NA NA NA
GLY G:123 G:143 10.0 0.133 T 77.9 13.5 NA NA NA
GLY H:123 H:143 20.0 0.267 T 39.6 25.7 NA NA NA
GLY I:123 I:143 14.0 0.187 T 61.4 27.5 NA NA NA
GLY J:123 J:143 11.0 0.147 T 59.7 12.9 NA NA NA
GLY K:123 K:143 27.0 0.36 T 37.4 24.7 NA NA NA
GLY L:123 L:143 11.0 0.147 T 61.2 20.8 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:123 A:1143 14.0 0.187 T 50.2 33.3 14.0 0.187 0.0 GD7
HOH
 2.793
3.586
 N
N
 O11
O
GLY B:123 B:2143 11.0 0.147 T 55.5 17.4 11.0 0.147 0.0 GD7
HOH
 2.616
3.703
 N
N
 O11
O
GLY C:123 C:3143 12.0 0.16 T 55.0 15.9 12.0 0.16 0.0 GD7
HOH
 2.697
3.560
 N
N
 O11
O
GLY D:123 D:4143 13.0 0.173 T 46.5 32.7 NA NA NA
GLY E:123 E:5143 10.0 0.133 T 59.0 15.3 NA NA NA
GLY F:123 F:6143 12.0 0.16 T 54.6 18.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:123 A:1143 21.0 0.28 T 56.6 27.8 21.0 0.28 0.0 NTJ
HOH
 2.776
3.498
 N
N
 O1
O
GLY B:123 B:2143 10.0 0.133 T 62.2 13.1 10.0 0.133 0.0 NTJ
HOH
 2.704
3.658
 N
N
 O1
O
GLY C:123 C:3143 12.0 0.16 T 58.1 15.5 12.0 0.16 0.0 NTJ
HOH
 2.662
3.621
 N
N
 O1
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:123 A:143 19.0 0.253 T 56.7 19.4 19.0 0.253 0.0 HOH
 2.756
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:123 A:143 14.0 0.187 T 60.6 21.3 14.0 0.187 0.0 HOH
 2.638
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:123 A:143 26.0 0.347 T 64.2 16.9 26.0 0.347 0.0 HOH
 2.801
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:122 A:143 13.0 0.173 T 62.3 24.7 13.0 0.173 0.0 HOH
 2.580
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:120 A:1143 27.0 0.36 T 64.8 17.1 27.0 0.36 0.0 WW2
HOH
 2.597
8.803
 N
O
 O1
O
GLY B:120 B:2143 26.0 0.347 T 63.0 18.9 26.0 0.347 0.0 WW2
HOH
 2.570
7.451
 N
N
 O1
O
GLY C:120 C:3143 22.0 0.293 T 63.8 18.9 22.0 0.293 0.0 WW2
 2.371
 N
 O1
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:121 A:143 15.0 0.2 T 57.5 16.0 15.0 0.2 0.0 HOH
 2.720
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:143 A:143 13.0 0.173 T 62.6 21.2
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:144 A:144 39.0 0.52 T 71.6 13.2