Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857573 . C A CCDS32450.1:NM_001025195.1:c.428gGg>gTg_NP_001020366.1:p.143G>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:124 A:1142 13.0 0.173 S 130.6 36.6 13.0 0.173 0.0 THA
HOH
 3.712
2.573
 CA
N
 C11
O
GLY B:124 B:2142 13.0 0.173 S 130.1 30.7 13.0 0.173 0.0 THA
HOH
 3.746
2.658
 CA
N
 N15
O
GLY C:124 C:3142 9.0 0.12 S 137.0 31.5 9.0 0.12 0.0 THA
HOH
 3.948
2.583
 CA
N
 C2
O
GLY D:124 D:4142 12.0 0.16 S 140.0 29.8 12.0 0.16 0.0 THA
HOH
 3.911
2.555
 CA
N
 C11
O
GLY E:124 E:5142 12.0 0.16 S 133.8 33.0 12.0 0.16 0.0 THA
HOH
 3.811
2.707
 CA
N
 C14
O
GLY F:124 F:6142 12.0 0.16 S 132.4 28.5 12.0 0.16 0.0 THA
HOH
 3.876
2.510
 N
N
 C11
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:124 A:1142 11.0 0.147 S 138.5 21.0 11.0 0.147 0.0 CL
HTQ
HOH
 3.091
3.507
2.879
 N
C
C
 CL
C15
O
GLY B:124 B:2142 9.0 0.12 S 142.1 24.6 9.0 0.12 0.0 HTQ
HOH
 3.392
2.811
 CA
N
 C13
O
GLY C:124 C:3142 12.0 0.16 S 133.8 38.0 12.0 0.16 0.0 HTQ
HOH
 3.533
2.650
 C
N
 C15
O
GLY D:124 D:4142 11.0 0.147 S 135.6 36.3 NA NA NA
GLY E:124 E:5142 11.0 0.147 S 131.7 26.8 NA NA NA
GLY F:124 F:6142 9.0 0.12 S 145.4 25.0 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:124 A:1142 13.0 0.173 S 127.0 34.3 13.0 0.173 0.0 NLX
HOH
 3.516
2.927
 O
C
 C15
O
GLY B:124 B:2142 12.0 0.16 S 134.3 22.4 12.0 0.16 0.0 NLX
HOH
 3.594
2.478
 CA
N
 O1
O
GLY C:124 C:3142 11.0 0.147 S 128.7 16.3 11.0 0.147 0.0 NLX
HOH
 3.552
3.369
 N
N
 O2
O
GLY D:124 D:4142 14.0 0.187 S 136.0 30.9 14.0 0.187 0.0 NLX
HOH
 3.386
2.468
 C
N
 C15
O
GLY E:124 E:5142 10.0 0.133 S 140.9 14.4 10.0 0.133 0.0 NLX
HOH
 3.029
4.802
 CA
N
 C8
O
GLY F:124 F:6142 11.0 0.147 S 136.7 -0.3 11.0 0.147 0.0 NLX
HOH
 3.295
3.206
 C
CA
 C8
O
GLY G:124 G:1142 9.0 0.12 S 125.3 30.8 NA NA NA
GLY H:124 H:2142 11.0 0.147 S 134.9 29.3 NA NA NA
GLY I:124 I:3142 9.0 0.12 S 158.2 13.5 NA NA NA
GLY J:124 J:4142 15.0 0.2 S 130.4 30.1 NA NA NA
GLY K:124 K:5142 13.0 0.173 S 127.2 5.8 NA NA NA
GLY L:124 L:6142 11.0 0.147 S 162.3 24.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:124 A:1142 14.0 0.187 S 137.6 34.7 14.0 0.187 0.0 PLM
HOH
 3.492
2.499
 C
N
 C6
O
GLY B:124 B:2142 10.0 0.133 S 138.5 33.0 10.0 0.133 0.0 PLM
HOH
 4.061
2.838
 C
N
 C6
O
GLY C:124 C:3142 10.0 0.133 S 138.5 35.2 10.0 0.133 0.0 PLM
HOH
 4.104
2.915
 C
N
 C5
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:124 A:1142 13.0 0.173 S 130.4 43.1 13.0 0.173 0.0 F
PLM
HOH
 2.671
3.712
3.031
 N
CA
C
 F
C5
O
GLY B:124 B:2142 10.0 0.133 S 139.3 27.3 10.0 0.133 0.0 F
PLM
HOH
 2.975
3.952
3.253
 N
C
N
 F
C5
O
GLY C:124 C:3142 11.0 0.147 S 140.0 34.6 11.0 0.147 0.0 F
COA
HOH
 2.703
4.029
3.025
 N
CA
N
 F
O5P
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:124 A:1142 14.0 0.187 S 136.5 23.6 14.0 0.187 0.0 TCH
HOH
 2.718
3.177
 C
CA
 O12
O
GLY B:124 B:2142 16.0 0.213 S 133.9 23.6 16.0 0.213 0.0 TCH
HOH
 3.762
2.440
 CA
N
 O12
O
GLY C:124 C:3142 14.0 0.187 S 135.8 25.6 14.0 0.187 0.0 TCH
HOH
 3.388
3.065
 C
N
 O12
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:124 A:1142 12.0 0.16 S 133.5 30.3 12.0 0.16 0.0 COA
HOH
 3.670
2.766
 CA
N
 C7P
O
GLY B:124 B:2142 11.0 0.147 S 134.0 33.2 11.0 0.147 0.0 COA
HOH
 3.909
2.717
 CA
N
 C7P
O
GLY C:124 C:3142 10.0 0.133 S 138.6 26.6 10.0 0.133 0.0 COA
HOH
 3.931
2.672
 C
N
 C5P
O
GLY D:124 D:4142 13.0 0.173 S 133.4 26.1 13.0 0.173 0.0 COA
HOH
 3.620
2.677
 CA
N
 C7P
O
GLY E:124 E:5142 12.0 0.16 S 139.1 26.3 12.0 0.16 0.0 COA
HOH
 3.720
2.757
 CA
N
 C7P
O
GLY F:124 F:6142 11.0 0.147 S 134.6 32.4 11.0 0.147 0.0 COA
HOH
 3.823
2.651
 CA
N
 C7P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:122 A:142 12.0 0.16 S 142.9 37.5 12.0 0.16 0.0 CTX
HOH
 3.885
2.586
 CA
N
 C9
O
GLY B:122 B:142 12.0 0.16 S 143.5 29.0 12.0 0.16 0.0 CTX
HOH
 3.840
3.191
 CA
N
 C9
O
GLY C:122 C:142 12.0 0.16 S 136.8 44.2 12.0 0.16 0.0 CTX
HOH
 3.829
2.464
 CA
N
 C9
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:122 A:142 11.0 0.147 S 134.8 31.9 11.0 0.147 0.0 SMB
HOH
 4.187
2.815
 C
C
 C3
O
GLY B:122 B:142 11.0 0.147 S 130.1 22.9 11.0 0.147 0.0 SMB
HOH
 3.885
2.778
 C
N
 C3
O
GLY C:122 C:142 11.0 0.147 S 135.1 39.6 11.0 0.147 0.0 SMB
HOH
 3.117
2.877
 CA
C
 O2
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:122 A:142 13.0 0.173 S 133.9 40.7 13.0 0.173 0.0 EEE
HOH
 4.228
3.115
 C
N
 C2
O
GLY B:122 B:142 13.0 0.173 S 132.2 33.8 13.0 0.173 0.0 EEE
HOH
 3.885
2.615
 C
N
 C2
O
GLY C:122 C:142 12.0 0.16 S 135.3 33.9 12.0 0.16 0.0 EEE
HOH
 3.718
2.592
 C
N
 C2
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:122 A:142 11.0 0.147 S 130.8 53.3 11.0 0.147 0.0 BEZ
HOH
 4.150
2.398
 CA
N
 C5
O
GLY B:122 B:142 7.0 0.093 S 121.1 36.6 7.0 0.093 0.0 BEZ
HOH
 4.216
3.117
 C
N
 C
O
GLY C:122 C:142 11.0 0.147 S 145.1 16.4 11.0 0.147 0.0 BEZ
HOH
 2.568
3.172
 N
CA
 O2
O
GLY D:122 D:142 13.0 0.173 S 135.1 41.5 NA NA NA
GLY E:122 E:142 12.0 0.16 S 128.0 24.7 NA NA NA
GLY F:122 F:142 10.0 0.133 S 123.5 40.3 NA NA NA
GLY G:122 G:142 13.0 0.173 S 140.0 32.8 NA NA NA
GLY H:122 H:142 15.0 0.2 S 109.4 46.4 NA NA NA
GLY I:122 I:142 11.0 0.147 S 173.4 18.2 NA NA NA
GLY J:122 J:142 8.0 0.107 S 147.2 34.9 NA NA NA
GLY K:122 K:142 13.0 0.173 S 138.9 45.6 NA NA NA
GLY L:122 L:142 13.0 0.173 S 117.5 17.0 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:122 A:1142 9.0 0.12 S 133.2 38.2 9.0 0.12 0.0 GD7
HOH
 2.486
3.085
 N
C
 O11
O
GLY B:122 B:2142 7.0 0.093 S 140.0 32.8 7.0 0.093 0.0 GD7
HOH
 2.550
3.110
 N
N
 O11
O
GLY C:122 C:3142 9.0 0.12 S 131.0 32.0 9.0 0.12 0.0 GD7
HOH
 2.623
3.117
 N
C
 O11
O
GLY D:122 D:4142 9.0 0.12 S 134.8 43.1 NA NA NA
GLY E:122 E:5142 7.0 0.093 S 137.8 28.2 NA NA NA
GLY F:122 F:6142 10.0 0.133 S 129.8 33.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:122 A:1142 11.0 0.147 S 132.1 31.7 11.0 0.147 0.0 NTJ
HOH
 2.778
3.031
 N
C
 O1
O
GLY B:122 B:2142 10.0 0.133 S 133.5 24.7 10.0 0.133 0.0 NTJ
HOH
 2.944
3.317
 N
N
 O1
O
GLY C:122 C:3142 9.0 0.12 S 136.6 33.0 9.0 0.12 0.0 NTJ
HOH
 2.709
3.134
 N
C
 O1
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:122 A:142 13.0 0.173 S 126.9 34.2 13.0 0.173 0.0 HOH
 3.009
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:122 A:142 11.0 0.147 S 128.0 34.0 11.0 0.147 0.0 HOH
 2.777
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:122 A:142 11.0 0.147 S 128.3 34.2 11.0 0.147 0.0 HOH
 3.100
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:121 A:142 10.0 0.133 S 124.4 27.5 10.0 0.133 0.0 HOH
 2.780
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:119 A:1142 12.0 0.16 S 148.4 25.0 12.0 0.16 0.0 WW2
HOH
 2.716
8.438
 N
O
 O1
O
GLY B:119 B:2142 13.0 0.173 S 149.4 25.9 13.0 0.173 0.0 WW2
HOH
 2.352
4.948
 N
N
 O1
O
GLY C:119 C:3142 12.0 0.16 S 148.2 24.6 12.0 0.16 0.0 WW2
 2.406
 N
 O1
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:120 A:142 10.0 0.133 S 133.2 34.9 10.0 0.133 0.0 HOH
 2.719
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:142 A:142 8.0 0.107 S 110.8 29.9
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:143 A:143 17.0 0.227 S 109.8 31.3