Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55857577 . C A CCDS32450.1:NM_001025195.1:c.424Gga>Tga_NP_001020366.1:p.142G>* Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:123 A:1141 0.0 0.0 -101.7 -170.4 0.0 0.0 0.0 THA
HOH
 4.604
2.903
 C
O
 C1
O
GLY B:123 B:2141 0.0 0.0 -100.0 -168.0 0.0 0.0 0.0 THA
HOH
 4.865
3.004
 C
O
 N15
O
GLY C:123 C:3141 0.0 0.0 -103.6 -173.9 0.0 0.0 0.0 THA
HOH
 4.978
2.752
 C
N
 N15
O
GLY D:123 D:4141 1.0 0.013 -97.8 -177.7 1.0 0.013 0.0 THA
HOH
 4.945
2.823
 C
N
 C2
O
GLY E:123 E:5141 0.0 0.0 -96.8 -171.2 0.0 0.0 0.0 THA
HOH
 4.912
2.812
 C
N
 C11
O
GLY F:123 F:6141 0.0 0.0 -96.8 -169.2 0.0 0.0 0.0 THA
HOH
 4.822
2.766
 C
N
 C2
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:123 A:1141 0.0 0.0 -93.6 -171.1 0.0 0.0 0.0 CL
HTQ
HOH
 4.076
4.883
2.867
 C
C
N
 CL
C13
O
GLY B:123 B:2141 0.0 0.0 -96.3 -174.5 0.0 0.0 0.0 HTQ
HOH
 4.688
2.937
 C
N
 O20
O
GLY C:123 C:3141 0.0 0.0 -110.0 -169.1 0.0 0.0 0.0 HTQ
HOH
 5.455
2.909
 C
O
 O12
O
GLY D:123 D:4141 0.0 0.0 -104.8 -171.7 NA NA NA
GLY E:123 E:5141 0.0 0.0 -99.3 -165.6 NA NA NA
GLY F:123 F:6141 0.0 0.0 -106.6 -177.1 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:123 A:1141 0.0 0.0 -100.6 -168.6 0.0 0.0 0.0 NLX
HOH
 5.016
2.483
 C
N
 O1
O
GLY B:123 B:2141 0.0 0.0 -112.8 -169.9 0.0 0.0 0.0 NLX
HOH
 4.800
2.846
 C
O
 O1
O
GLY C:123 C:3141 1.0 0.013 -96.0 -164.6 1.0 0.013 0.0 NLX
HOH
 4.705
2.888
 C
O
 O2
O
GLY D:123 D:4141 0.0 0.0 -106.0 -173.5 0.0 0.0 0.0 NLX
HOH
 4.399
2.954
 CA
C
 O1
O
GLY E:123 E:5141 0.0 0.0 -89.2 -172.7 0.0 0.0 0.0 NLX
HOH
 4.108
2.675
 C
N
 C7
O
GLY F:123 F:6141 0.0 0.0 -96.8 -171.7 0.0 0.0 0.0 NLX
HOH
 5.265
3.154
 C
O
 O4
O
GLY G:123 G:1141 0.0 0.0 -94.7 -169.1 NA NA NA
GLY H:123 H:2141 0.0 0.0 -104.4 -172.5 NA NA NA
GLY I:123 I:3141 0.0 0.0 -98.9 164.8 NA NA NA
GLY J:123 J:4141 0.0 0.0 -101.0 -177.0 NA NA NA
GLY K:123 K:5141 0.0 0.0 -96.0 -163.1 NA NA NA
GLY L:123 L:6141 2.0 0.027 81.3 147.0 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:123 A:1141 0.0 0.0 -103.1 -172.8 0.0 0.0 0.0 PLM
HOH
 5.585
2.584
 C
N
 C6
O
GLY B:123 B:2141 0.0 0.0 -103.6 -173.7 0.0 0.0 0.0 PLM
HOH
 6.212
2.799
 C
N
 C5
O
GLY C:123 C:3141 0.0 0.0 -105.9 -173.2 0.0 0.0 0.0 PLM
HOH
 6.006
3.949
 C
C
 C5
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:123 A:1141 0.0 0.0 -108.6 -168.1 0.0 0.0 0.0 F
PLM
HOH
 3.762
5.664
2.931
 C
C
N
 F
C5
O
GLY B:123 B:2141 0.0 0.0 -103.6 -171.5 0.0 0.0 0.0 F
PLM
HOH
 3.951
5.912
3.140
 C
C
N
 F
C5
O
GLY C:123 C:3141 0.0 0.0 -111.2 -173.7 0.0 0.0 0.0 F
COA
HOH
 3.690
5.380
2.725
 C
C
O
 F
O5P
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:123 A:1141 0.0 0.0 -94.6 -166.6 0.0 0.0 0.0 TCH
HOH
 4.892
2.946
 C
N
 O12
O
GLY B:123 B:2141 0.0 0.0 -95.0 -165.2 0.0 0.0 0.0 TCH
HOH
 5.011
3.019
 C
O
 O12
O
GLY C:123 C:3141 0.0 0.0 -95.2 -166.3 0.0 0.0 0.0 TCH
HOH
 5.742
2.732
 C
N
 O12
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:123 A:1141 0.0 0.0 -100.0 -170.7 0.0 0.0 0.0 COA
HOH
 5.262
2.770
 C
N
 O5P
O
GLY B:123 B:2141 0.0 0.0 -95.3 -173.7 0.0 0.0 0.0 COA
HOH
 5.481
2.912
 C
N
 C5P
O
GLY C:123 C:3141 0.0 0.0 -96.3 -174.3 0.0 0.0 0.0 COA
HOH
 5.485
2.921
 C
N
 C5P
O
GLY D:123 D:4141 0.0 0.0 -94.7 -173.1 0.0 0.0 0.0 COA
HOH
 4.852
2.811
 C
N
 O5P
O
GLY E:123 E:5141 0.0 0.0 -100.7 -175.4 0.0 0.0 0.0 COA
HOH
 5.168
2.957
 C
N
 O5P
O
GLY F:123 F:6141 0.0 0.0 -98.1 -172.2 0.0 0.0 0.0 COA
HOH
 5.282
2.960
 C
N
 O5P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:121 A:141 1.0 0.013 -114.6 -173.8 1.0 0.013 0.0 CTX
HOH
 4.648
2.987
 C
N
 C10
O
GLY B:121 B:141 1.0 0.013 -107.1 -172.8 1.0 0.013 0.0 CTX
HOH
 4.603
4.227
 C
C
 C10
O
GLY C:121 C:141 1.0 0.013 -113.5 -171.4 1.0 0.013 0.0 CTX
HOH
 4.752
2.891
 C
N
 C10
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:121 A:141 0.0 0.0 -94.1 -169.7 0.0 0.0 0.0 SMB
HOH
 5.342
2.780
 C
N
 O1
O
GLY B:121 B:141 0.0 0.0 -95.0 -169.8 0.0 0.0 0.0 SMB
HOH
 5.140
2.892
 C
N
 O1
O
GLY C:121 C:141 0.0 0.0 -102.3 -173.1 0.0 0.0 0.0 SMB
HOH
 4.541
3.305
 C
C
 O2
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:121 A:141 0.0 0.0 -99.5 -167.4 0.0 0.0 0.0 EEE
HOH
 6.483
3.018
 C
N
 C2
O
GLY B:121 B:141 0.0 0.0 -95.8 -169.3 0.0 0.0 0.0 EEE
HOH
 5.799
2.727
 C
O
 O1
O
GLY C:121 C:141 0.0 0.0 -100.4 -172.0 0.0 0.0 0.0 EEE
HOH
 5.865
3.044
 C
N
 C2
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:121 A:141 0.0 0.0 -116.1 -172.9 0.0 0.0 0.0 BEZ
HOH
 5.643
3.423
 C
C
 C5
O
GLY B:121 B:141 0.0 0.0 -95.5 -158.1 0.0 0.0 0.0 BEZ
HOH
 5.477
4.205
 C
C
 O2
O
GLY C:121 C:141 1.0 0.013 -98.2 -171.1 1.0 0.013 0.0 BEZ
HOH
 3.643
3.244
 C
C
 O2
O
GLY D:121 D:141 0.0 0.0 -94.8 -169.2 NA NA NA
GLY E:121 E:141 0.0 0.0 -99.6 -161.6 NA NA NA
GLY F:121 F:141 0.0 0.0 -122.0 -163.9 NA NA NA
GLY G:121 G:141 0.0 0.0 -157.1 -173.7 NA NA NA
GLY H:121 H:141 0.0 0.0 -112.6 -152.8 NA NA NA
GLY I:121 I:141 1.0 0.013 -98.0 159.6 NA NA NA
GLY J:121 J:141 0.0 0.0 -116.3 177.6 NA NA NA
GLY K:121 K:141 0.0 0.0 -108.4 -176.7 NA NA NA
GLY L:121 L:141 2.0 0.027 -85.0 -151.9 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:121 A:1141 0.0 0.0 -111.1 -170.1 0.0 0.0 0.0 GD7
HOH
 3.495
2.899
 C
N
 O11
O
GLY B:121 B:2141 0.0 0.0 -110.5 -174.4 0.0 0.0 0.0 GD7
HOH
 3.519
2.890
 C
O
 O11
O
GLY C:121 C:3141 0.0 0.0 -102.5 -170.2 0.0 0.0 0.0 GD7
HOH
 3.600
2.847
 C
O
 O11
O
GLY D:121 D:4141 0.0 0.0 -114.7 -172.5 NA NA NA
GLY E:121 E:5141 1.0 0.013 -101.8 -172.0 NA NA NA
GLY F:121 F:6141 0.0 0.0 -101.0 -169.3 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:121 A:1141 0.0 0.0 -99.7 -169.8 0.0 0.0 0.0 NTJ
HOH
 3.739
2.655
 C
N
 O1
O
GLY B:121 B:2141 0.0 0.0 -102.0 -167.6 0.0 0.0 0.0 NTJ
HOH
 3.982
2.935
 C
N
 O1
O
GLY C:121 C:3141 0.0 0.0 -98.9 -173.4 0.0 0.0 0.0 NTJ
HOH
 3.685
2.780
 C
N
 O1
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:121 A:141 0.0 0.0 -92.0 -167.8 0.0 0.0 0.0 HOH
 2.751
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:121 A:141 0.0 0.0 -109.1 -172.6 0.0 0.0 0.0 HOH
 2.818
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:121 A:141 0.0 0.0 -96.4 -170.2 0.0 0.0 0.0 HOH
 2.875
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:120 A:141 0.0 0.0 -96.1 -165.9 0.0 0.0 0.0 HOH
 2.949
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:118 A:1141 0.0 0.0 -112.7 -179.6 0.0 0.0 0.0 WW2
HOH
 3.690
6.185
 C
N
 O1
O
GLY B:118 B:2141 0.0 0.0 -113.3 178.3 0.0 0.0 0.0 WW2
HOH
 3.354
2.292
 C
N
 O1
O
GLY C:118 C:3141 0.0 0.0 -115.1 -179.9 0.0 0.0 0.0 WW2
 3.510
 C
 O1
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:119 A:141 1.0 0.013 -99.4 -174.9 1.0 0.013 0.0 HOH
 3.107
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:141 A:141 0.0 0.0 -76.8 -161.0
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:142 A:142 5.0 0.067 -81.5 -157.6