Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55860095 . G A CCDS32450.1:NM_001025195.1:c.373Cct>Tct_NP_001020366.1:p.125P>S Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 PRO A:106 A:1124 8.0 0.055 -84.0 -12.7 8.0 0.055 0.0 HOH
 3.328
 O
 O
PRO B:106 B:2124 8.0 0.055 -86.2 -6.9 8.0 0.055 0.0 HOH
 2.876
 O
 O
PRO C:106 C:3124 9.0 0.062 -87.8 -6.8 9.0 0.062 0.0 HOH
 2.939
 O
 O
PRO D:106 D:4124 10.0 0.069 -89.6 -5.8 10.0 0.069 0.0 HOH
 2.675
 O
 O
PRO E:106 E:5124 4.0 0.028 -93.1 -3.1 4.0 0.028 0.0 HOH
 4.056
 O
 O
PRO F:106 F:6124 10.0 0.069 -89.4 0.5 10.0 0.069 0.0 HOH
 2.614
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 PRO A:106 A:1124 8.0 0.055 -82.3 -4.7 8.0 0.055 0.0 HOH
 2.935
 O
 O
PRO B:106 B:2124 3.0 0.021 -88.3 -10.0 3.0 0.021 0.0 HOH
 4.265
 O
 O
PRO C:106 C:3124 9.0 0.062 -87.0 -6.3 9.0 0.062 0.0 HOH
 2.661
 O
 O
PRO D:106 D:4124 5.0 0.034 -80.1 -18.5 NA NA NA
PRO E:106 E:5124 9.0 0.062 -84.4 -11.0 NA NA NA
PRO F:106 F:6124 10.0 0.069 -84.0 -5.2 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 PRO A:106 A:1124 4.0 0.028 -83.2 0.2 4.0 0.028 0.0 HOH
 7.164
 O
 O
PRO B:106 B:2124 12.0 0.083 -82.0 -5.7 12.0 0.083 0.0 HOH
 3.203
 O
 O
PRO C:106 C:3124 9.0 0.062 -92.7 3.7 9.0 0.062 0.0 HOH
 4.440
 CB
 O
PRO D:106 D:4124 12.0 0.083 -83.7 -9.4 12.0 0.083 0.0 HOH
 5.525
 O
 O
PRO E:106 E:5124 6.0 0.041 -86.4 -3.1 6.0 0.041 0.0 HOH
 2.795
 O
 O
PRO F:106 F:6124 6.0 0.041 -82.3 -21.2 6.0 0.041 0.0 HOH
 3.856
 O
 O
PRO G:106 G:1124 3.0 0.021 -89.0 -11.0 NA NA NA
PRO H:106 H:2124 10.0 0.069 -72.3 -12.1 NA NA NA
PRO I:106 I:3124 11.0 0.076 -92.6 -17.7 NA NA NA
PRO J:106 J:4124 17.0 0.117 -86.3 -9.3 NA NA NA
PRO K:106 K:5124 7.0 0.048 -88.0 -18.8 NA NA NA
PRO L:106 L:6124 9.0 0.062 -87.1 -19.4 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:106 A:1124 7.0 0.048 -88.5 -6.5 7.0 0.048 0.0 HOH
 3.155
 O
 O
PRO B:106 B:2124 5.0 0.034 -89.4 -6.0 5.0 0.034 0.0 HOH
 3.562
 CB
 O
PRO C:106 C:3124 6.0 0.041 -89.6 -7.1 6.0 0.041 0.0 HOH
 4.401
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:106 A:1124 11.0 0.076 -88.2 -4.0 11.0 0.076 0.0 HOH
 2.935
 O
 O
PRO B:106 B:2124 7.0 0.048 -91.4 0.8 7.0 0.048 0.0 HOH
 2.864
 O
 O
PRO C:106 C:3124 2.0 0.014 -91.3 1.5 2.0 0.014 0.0 HOH
 4.258
 CB
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:106 A:1124 8.0 0.055 -87.1 3.8 8.0 0.055 0.0 HOH
 2.629
 O
 O
PRO B:106 B:2124 8.0 0.055 -87.5 3.4 8.0 0.055 0.0 HOH
 2.682
 O
 O
PRO C:106 C:3124 7.0 0.048 -87.0 3.4 7.0 0.048 0.0 HOH
 6.213
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:106 A:1124 12.0 0.083 -89.7 -1.5 12.0 0.083 0.0 HOH
 2.780
 O
 O
PRO B:106 B:2124 9.0 0.062 -87.5 -1.1 9.0 0.062 0.0 HOH
 3.174
 CB
 O
PRO C:106 C:3124 9.0 0.062 -84.7 -11.3 9.0 0.062 0.0 HOH
 2.972
 O
 O
PRO D:106 D:4124 11.0 0.076 -92.2 6.9 11.0 0.076 0.0 HOH
 2.916
 O
 O
PRO E:106 E:5124 4.0 0.028 -90.0 0.5 4.0 0.028 0.0 HOH
 2.921
 O
 O
PRO F:106 F:6124 7.0 0.048 -86.9 -6.3 7.0 0.048 0.0 HOH
 3.080
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:104 A:124 8.0 0.055 -86.6 -2.4 8.0 0.055 0.0
PRO B:104 B:124 9.0 0.062 -78.9 -7.5 9.0 0.062 0.0 HOH
 9.838
 CD
 O
PRO C:104 C:124 7.0 0.048 -83.9 -4.7 7.0 0.048 0.0 HOH
 5.852
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:104 A:124 10.0 0.069 -92.1 -4.3 10.0 0.069 0.0 HOH
 2.744
 O
 O
PRO B:104 B:124 9.0 0.062 -95.8 -10.5 9.0 0.062 0.0 HOH
 4.142
 O
 O
PRO C:104 C:124 6.0 0.041 -89.8 -4.6 6.0 0.041 0.0 HOH
 4.357
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:104 A:124 6.0 0.041 -82.4 -11.4 6.0 0.041 0.0 HOH
 3.169
 O
 O
PRO B:104 B:124 6.0 0.041 -86.5 -9.0 6.0 0.041 0.0 HOH
 2.634
 O
 O
PRO C:104 C:124 6.0 0.041 -83.3 -9.4 6.0 0.041 0.0 HOH
 4.145
 CB
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:104 A:124 6.0 0.041 -93.7 22.3 6.0 0.041 0.0 HOH
 7.525
 CG
 O
PRO B:104 B:124 14.0 0.097 -99.1 22.7 14.0 0.097 0.0
PRO C:104 C:124 4.0 0.028 -92.3 5.9 4.0 0.028 0.0
PRO D:104 D:124 13.0 0.09 -85.0 5.5 NA NA NA
PRO E:104 E:124 10.0 0.069 -99.6 18.4 NA NA NA
PRO F:104 F:124 2.0 0.014 -89.1 8.7 NA NA NA
PRO G:104 G:124 1.0 0.007 -92.6 5.5 NA NA NA
PRO H:104 H:124 12.0 0.083 -85.5 4.0 NA NA NA
PRO I:104 I:124 12.0 0.083 -104.1 26.0 NA NA NA
PRO J:104 J:124 3.0 0.021 -86.3 26.9 NA NA NA
PRO K:104 K:124 11.0 0.076 -92.9 12.3 NA NA NA
PRO L:104 L:124 10.0 0.069 -97.7 20.6 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 PRO A:104 A:1124 10.0 0.069 -82.6 -10.3 10.0 0.069 0.0 HOH
 3.044
 O
 O
PRO B:104 B:2124 10.0 0.069 -92.0 4.2 10.0 0.069 0.0 HOH
 2.729
 O
 O
PRO C:104 C:3124 6.0 0.041 -90.9 -2.0 6.0 0.041 0.0 HOH
 6.158
 O
 O
PRO D:104 D:4124 9.0 0.062 -84.0 -11.7 NA NA NA
PRO E:104 E:5124 8.0 0.055 -93.8 4.2 NA NA NA
PRO F:104 F:6124 6.0 0.041 -89.9 -11.0 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 PRO A:104 A:1124 12.0 0.083 -88.9 -6.2 12.0 0.083 0.0 HOH
 2.670
 O
 O
PRO B:104 B:2124 8.0 0.055 -89.5 -0.7 8.0 0.055 0.0 HOH
 4.192
 CB
 O
PRO C:104 C:3124 6.0 0.041 -92.9 0.9 6.0 0.041 0.0 HOH
 3.992
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 PRO A:104 A:124 18.0 0.124 -88.2 4.1 18.0 0.124 0.0 HOH
 3.793
 C
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 PRO A:104 A:124 30.0 0.207 -87.9 -1.4 30.0 0.207 0.0 HOH
 2.956
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 PRO A:104 A:124 12.0 0.083 -83.4 -2.4 12.0 0.083 0.0 HOH
 2.699
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 PRO A:103 A:124 8.0 0.055 -87.1 1.1 8.0 0.055 0.0 IOD
HOH
 4.283
4.475
 C
CB
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 PRO A:101 A:1124 11.0 0.076 -82.8 -10.3 11.0 0.076 0.0
PRO B:101 B:2124 11.0 0.076 -83.1 -11.4 11.0 0.076 0.0
PRO C:101 C:3124 26.0 0.179 -82.2 -10.6 26.0 0.179 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 PRO A:102 A:124 10.0 0.069 -90.9 -9.6 10.0 0.069 0.0 HOH
 5.331
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 PRO A:124 A:124 11.0 0.076 -84.0 -4.0
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 PRO A:125 A:125 12.0 0.083 -83.0 -3.7