Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55860158 . T A CCDS32450.1:NM_001025195.1:c.310Aac>Tac_NP_001020366.1:p.104N>Y Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ASN A:85 A:1103 2.0 0.013 -103.7 -2.9 2.0 0.013 0.0 HOH
 3.342
 CB
 O
ASN B:85 B:2103 3.0 0.019 -102.7 6.5 3.0 0.019 0.0 HOH
 3.237
 CB
 O
ASN C:85 C:3103 2.0 0.013 -104.0 3.9 2.0 0.013 0.0 HOH
 3.783
 ND2
 O
ASN D:85 D:4103 2.0 0.013 -103.3 2.0 2.0 0.013 0.0 HOH
 3.790
 ND2
 O
ASN E:85 E:5103 2.0 0.013 -97.9 5.2 2.0 0.013 0.0 HOH
 3.083
 CB
 O
ASN F:85 F:6103 3.0 0.019 -101.1 0.5 3.0 0.019 0.0 HOH
 3.195
 CB
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASN A:85 A:1103 2.0 0.013 S -100.3 2.9 2.0 0.013 0.0 HOH
 3.412
 CB
 O
ASN B:85 B:2103 2.0 0.013 -125.2 4.1 2.0 0.013 0.0 HOH
 3.072
 CB
 O
ASN C:85 C:3103 2.0 0.013 -104.1 -4.0 2.0 0.013 0.0 HOH
 3.243
 CB
 O
ASN D:85 D:4103 1.0 0.006 -108.8 -5.0 NA NA NA
ASN E:85 E:5103 2.0 0.013 -100.9 -8.8 NA NA NA
ASN F:85 F:6103 2.0 0.013 -105.5 1.7 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASN A:85 A:1103 3.0 0.019 -101.9 13.0 3.0 0.019 0.0 HOH
 3.837
 CB
 O
ASN B:85 B:2103 2.0 0.013 -114.8 11.2 2.0 0.013 0.0 HOH
 3.708
 ND2
 O
ASN C:85 C:3103 2.0 0.013 -110.2 11.7 2.0 0.013 0.0 HOH
 3.455
 ND2
 O
ASN D:85 D:4103 3.0 0.019 -111.6 16.4 3.0 0.019 0.0 HOH
 4.864
 O
 O
ASN E:85 E:5103 2.0 0.013 -114.3 7.3 2.0 0.013 0.0 HOH
 3.300
 CB
 O
ASN F:85 F:6103 2.0 0.013 -108.1 10.4 2.0 0.013 0.0 HOH
 3.447
 ND2
 O
ASN G:85 G:1103 3.0 0.019 -100.2 -8.7 NA NA NA
ASN H:85 H:2103 1.0 0.006 -108.7 8.8 NA NA NA
ASN I:85 I:3103 2.0 0.013 -90.8 -12.5 NA NA NA
ASN J:85 J:4103 2.0 0.013 -126.8 6.4 NA NA NA
ASN K:85 K:5103 2.0 0.013 -119.8 27.9 NA NA NA
ASN L:85 L:6103 3.0 0.019 -108.0 -10.1 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:85 A:1103 2.0 0.013 -109.0 -1.3 2.0 0.013 0.0 HOH
 3.489
 ND2
 O
ASN B:85 B:2103 2.0 0.013 -109.8 -2.2 2.0 0.013 0.0 HOH
 2.987
 CB
 O
ASN C:85 C:3103 2.0 0.013 -109.4 -2.8 2.0 0.013 0.0 HOH
 7.304
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:85 A:1103 1.0 0.006 -101.8 -5.0 1.0 0.006 0.0 HOH
 3.009
 CB
 O
ASN B:85 B:2103 2.0 0.013 -106.9 -7.1 2.0 0.013 0.0 HOH
 3.972
 ND2
 O
ASN C:85 C:3103 1.0 0.006 -104.3 -10.6 1.0 0.006 0.0 HOH
 3.509
 CB
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:85 A:1103 2.0 0.013 -98.1 -4.3 2.0 0.013 0.0 HOH
 3.218
 CB
 O
ASN B:85 B:2103 2.0 0.013 -97.3 -4.9 2.0 0.013 0.0 HOH
 3.630
 ND2
 O
ASN C:85 C:3103 1.0 0.006 -98.2 -4.8 1.0 0.006 0.0 HOH
 3.146
 CB
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:85 A:1103 2.0 0.013 -99.3 -2.8 2.0 0.013 0.0 HOH
 3.362
 CB
 O
ASN B:85 B:2103 2.0 0.013 -100.2 -1.5 2.0 0.013 0.0 HOH
 3.403
 CB
 O
ASN C:85 C:3103 2.0 0.013 -100.7 2.9 2.0 0.013 0.0 HOH
 3.135
 CB
 O
ASN D:85 D:4103 2.0 0.013 -95.5 -4.2 2.0 0.013 0.0 HOH
 3.190
 CB
 O
ASN E:85 E:5103 2.0 0.013 -100.8 -3.1 2.0 0.013 0.0 HOH
 3.201
 CB
 O
ASN F:85 F:6103 3.0 0.019 -101.9 7.8 3.0 0.019 0.0 HOH
 3.286
 CB
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:83 A:103 2.0 0.013 -100.2 4.9 2.0 0.013 0.0 HOH
 7.456
 OD1
 O
ASN B:83 B:103 2.0 0.013 -92.0 -3.2 2.0 0.013 0.0 HOH
 4.113
 ND2
 O
ASN C:83 C:103 1.0 0.006 -98.6 4.9 1.0 0.006 0.0 HOH
 5.535
 N
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:83 A:103 2.0 0.013 -97.8 12.3 2.0 0.013 0.0 HOH
 3.452
 CB
 O
ASN B:83 B:103 2.0 0.013 -119.5 -3.2 2.0 0.013 0.0 HOH
 3.309
 CB
 O
ASN C:83 C:103 3.0 0.019 -110.2 4.0 3.0 0.019 0.0 HOH
 4.768
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:83 A:103 2.0 0.013 -104.8 -1.4 2.0 0.013 0.0 HOH
 3.183
 CB
 O
ASN B:83 B:103 3.0 0.019 -101.0 -3.6 3.0 0.019 0.0 HOH
 3.614
 ND2
 O
ASN C:83 C:103 2.0 0.013 -104.8 -1.6 2.0 0.013 0.0 HOH
 2.959
 CB
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:83 A:103 1.0 0.006 -121.3 19.2 1.0 0.006 0.0 HOH
 6.060
 N
 O
ASN B:83 B:103 2.0 0.013 -124.9 -14.7 2.0 0.013 0.0 HOH
 3.504
 CB
 O
ASN C:83 C:103 3.0 0.019 -117.2 2.4 3.0 0.019 0.0 HOH
 7.448
 OD1
 O
ASN D:83 D:103 2.0 0.013 -105.6 20.2 NA NA NA
ASN E:83 E:103 2.0 0.013 -126.7 6.7 NA NA NA
ASN F:83 F:103 2.0 0.013 -121.1 13.2 NA NA NA
ASN G:83 G:103 2.0 0.013 -100.6 -4.2 NA NA NA
ASN H:83 H:103 2.0 0.013 -118.8 15.5 NA NA NA
ASN I:83 I:103 2.0 0.013 -124.7 -0.1 NA NA NA
ASN J:83 J:103 3.0 0.019 -109.6 -25.1 NA NA NA
ASN K:83 K:103 3.0 0.019 -112.4 17.7 NA NA NA
ASN L:83 L:103 1.0 0.006 -175.3 16.4 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASN A:83 A:1103 2.0 0.013 -101.2 0.1 2.0 0.013 0.0 HOH
 3.762
 ND2
 O
ASN B:83 B:2103 2.0 0.013 -105.0 -5.2 2.0 0.013 0.0 HOH
 3.819
 ND2
 O
ASN C:83 C:3103 2.0 0.013 -109.9 4.0 2.0 0.013 0.0 HOH
 3.043
 CB
 O
ASN D:83 D:4103 1.0 0.006 -100.6 5.8 NA NA NA
ASN E:83 E:5103 2.0 0.013 -103.8 -4.4 NA NA NA
ASN F:83 F:6103 2.0 0.013 -112.0 2.5 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASN A:83 A:1103 2.0 0.013 -97.4 -0.7 2.0 0.013 0.0 HOH
 3.137
 CB
 O
ASN B:83 B:2103 2.0 0.013 -99.7 -11.4 2.0 0.013 0.0 HOH
 3.661
 ND2
 O
ASN C:83 C:3103 3.0 0.019 -104.8 -3.3 3.0 0.019 0.0 HOH
 3.239
 CB
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ASN A:83 A:103 2.0 0.013 -96.8 1.7 2.0 0.013 0.0 HOH
 3.259
 CB
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ASN A:83 A:103 2.0 0.013 -95.4 -0.1 2.0 0.013 0.0 HOH
 3.380
 CB
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASN A:83 A:103 2.0 0.013 -86.9 -4.4 2.0 0.013 0.0 HOH
 3.403
 CB
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASN A:82 A:103 3.0 0.019 -93.8 9.1 3.0 0.019 0.0 IOD
HOH
 8.335
3.340
 N
CB
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ASN A:80 A:1103 3.0 0.019 -108.2 15.9 3.0 0.019 0.0
ASN B:80 B:2103 3.0 0.019 -107.5 16.6 3.0 0.019 0.0 HOH
 3.564
 ND2
 O
ASN C:80 C:3103 8.0 0.05 -107.9 16.2 8.0 0.05 0.0 HOH
 7.679
 OD1
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ASN A:81 A:103 0.0 0.0 S -101.2 25.5 0.0 0.0 0.0 HOH
 3.145
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ASN A:103 A:103 1.0 0.006 -80.5 -2.1
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ASN A:104 A:104 97.0 0.606 -92.8 8.3