Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55860184 . C A CCDS32450.1:NM_001025195.1:c.284gGg>gTg_NP_001020366.1:p.95G>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:76 A:1094 2.0 0.027 H -57.5 -49.4 2.0 0.027 0.0 THA
HOH
 8.262
2.682
 N
O
 C13
O
GLY B:76 B:2094 2.0 0.027 H -63.2 -49.4 2.0 0.027 0.0 THA
HOH
 7.471
2.882
 N
O
 C6
O
GLY C:76 C:3094 2.0 0.027 H -62.8 -40.5 2.0 0.027 0.0 THA
HOH
 7.508
2.689
 N
O
 C6
O
GLY D:76 D:4094 1.0 0.013 H -61.3 -52.3 1.0 0.013 0.0 THA
HOH
 8.168
3.105
 N
O
 C6
O
GLY E:76 E:5094 2.0 0.027 H -62.4 -45.8 2.0 0.027 0.0 THA
HOH
 7.301
2.872
 N
O
 C12
O
GLY F:76 F:6094 2.0 0.027 H -68.7 -42.5 2.0 0.027 0.0 THA
HOH
 8.091
2.721
 CA
O
 C13
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:76 A:1094 1.0 0.013 H -52.8 -53.1 1.0 0.013 0.0 HTQ
HOH
 5.716
4.378
 N
O
 C19
O
GLY B:76 B:2094 1.0 0.013 H -64.2 -43.0 1.0 0.013 0.0 HTQ
HOH
 5.509
2.799
 N
O
 C19
O
GLY C:76 C:3094 2.0 0.027 H -57.9 -55.3 2.0 0.027 0.0 HTQ
HOH
 6.208
3.127
 N
O
 C17
O
GLY D:76 D:4094 1.0 0.013 H -63.6 -35.3 NA NA NA
GLY E:76 E:5094 1.0 0.013 H -59.0 -50.7 NA NA NA
GLY F:76 F:6094 1.0 0.013 H -61.1 -52.1 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:76 A:1094 1.0 0.013 H -78.6 -43.6 1.0 0.013 0.0 NLX
HOH
 5.862
5.113
 N
C
 C17
O
GLY B:76 B:2094 1.0 0.013 H -62.9 -45.3 1.0 0.013 0.0 NLX
HOH
 8.176
4.949
 CA
O
 C2
O
GLY C:76 C:3094 3.0 0.04 H -59.3 -53.0 3.0 0.04 0.0 NLX
HOH
 9.865
4.931
 O
O
 O1
O
GLY D:76 D:4094 2.0 0.027 H -58.7 -54.6 2.0 0.027 0.0 NLX
HOH
 7.003
4.899
 N
O
 C19
O
GLY E:76 E:5094 3.0 0.04 H -57.4 -58.6 3.0 0.04 0.0 NLX
HOH
 7.328
5.508
 N
C
 C19
O
GLY F:76 F:6094 2.0 0.027 H -52.0 -55.0 2.0 0.027 0.0 NLX
HOH
 6.493
2.997
 O
O
 C19
O
GLY G:76 G:1094 1.0 0.013 H -62.3 -58.8 NA NA NA
GLY H:76 H:2094 2.0 0.027 H -66.5 -44.7 NA NA NA
GLY I:76 I:3094 4.0 0.053 H -72.7 -38.4 NA NA NA
GLY J:76 J:4094 3.0 0.04 H -73.0 -34.8 NA NA NA
GLY K:76 K:5094 1.0 0.013 H -53.8 -40.4 NA NA NA
GLY L:76 L:6094 2.0 0.027 H -46.1 -42.2 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:76 A:1094 2.0 0.027 H -58.7 -55.8 2.0 0.027 0.0 PLM
HOH
 5.756
3.143
 N
O
 CC
O
GLY B:76 B:2094 2.0 0.027 H -60.0 -55.4 2.0 0.027 0.0 PLM
HOH
 6.400
4.734
 N
O
 C9
O
GLY C:76 C:3094 2.0 0.027 H -60.8 -54.3 2.0 0.027 0.0 PLM
HOH
 6.439
3.030
 N
O
 C9
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:76 A:1094 2.0 0.027 H -61.4 -51.6 2.0 0.027 0.0 PLM
HOH
 5.283
3.019
 N
O
 C9
O
GLY B:76 B:2094 1.0 0.013 H -60.8 -50.4 1.0 0.013 0.0 PLM
HOH
 5.129
4.681
 N
O
 C9
O
GLY C:76 C:3094 2.0 0.027 H -69.7 -34.0 2.0 0.027 0.0 COA
HOH
 9.487
2.858
 N
O
 C6P
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:76 A:1094 3.0 0.04 H -57.4 -57.6 3.0 0.04 0.0 TCH
HOH
 5.605
2.811
 N
O
 O24
O
GLY B:76 B:2094 3.0 0.04 H -59.3 -56.3 3.0 0.04 0.0 TCH
HOH
 6.474
6.245
 N
N
 O2S
O
GLY C:76 C:3094 3.0 0.04 H -57.6 -57.0 3.0 0.04 0.0 TCH
HOH
 5.454
3.414
 N
O
 O24
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:76 A:1094 1.0 0.013 H -65.7 -42.6 1.0 0.013 0.0 COA
HOH
 4.488
2.707
 N
O
 O9P
O
GLY B:76 B:2094 2.0 0.027 H -62.3 -42.7 2.0 0.027 0.0 COA
HOH
 4.730
2.780
 N
N
 O9P
O
GLY C:76 C:3094 2.0 0.027 H -64.6 -43.0 2.0 0.027 0.0 COA
HOH
 4.748
2.939
 N
O
 O9P
O
GLY D:76 D:4094 1.0 0.013 H -61.7 -44.5 1.0 0.013 0.0 COA
HOH
 4.609
2.825
 N
O
 O9P
O
GLY E:76 E:5094 1.0 0.013 H -67.0 -38.8 1.0 0.013 0.0 COA
HOH
 4.609
2.912
 N
O
 O9P
O
GLY F:76 F:6094 2.0 0.027 H -65.9 -43.9 2.0 0.027 0.0 COA
HOH
 4.498
2.770
 N
O
 O9P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:74 A:94 1.0 0.013 H -63.8 -60.9 1.0 0.013 0.0 CTX
HOH
 6.884
3.183
 N
O
 OL
O
GLY B:74 B:94 2.0 0.027 H -63.8 -56.8 2.0 0.027 0.0 CTX
HOH
 6.828
6.186
 N
N
 OL
O
GLY C:74 C:94 1.0 0.013 H -63.0 -52.5 1.0 0.013 0.0 CTX
HOH
 6.885
7.095
 N
C
 C6
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:74 A:94 4.0 0.053 H -62.1 -50.4 4.0 0.053 0.0 SMB
HOH
 8.393
3.123
 N
O
 C1
O
GLY B:74 B:94 2.0 0.027 H -59.0 -57.8 2.0 0.027 0.0 SMB
HOH
 8.449
4.940
 N
C
 C1
O
GLY C:74 C:94 1.0 0.013 H -61.7 -47.5 1.0 0.013 0.0 SMB
HOH
 9.887
3.154
 CA
O
 O2
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:74 A:94 1.0 0.013 H -56.9 -42.0 1.0 0.013 0.0 EEE
HOH
 8.932
3.031
 N
O
 C2
O
GLY B:74 B:94 1.0 0.013 H -59.5 -44.4 1.0 0.013 0.0 EEE
HOH
 9.106
2.998
 N
O
 C2
O
GLY C:74 C:94 1.0 0.013 H -61.6 -40.5 1.0 0.013 0.0 EEE
HOH
 8.834
4.365
 N
O
 C2
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:74 A:94 3.0 0.04 H -74.5 -36.6 3.0 0.04 0.0 BEZ
HOH
 8.422
7.223
 CA
N
 C4
O
GLY B:74 B:94 2.0 0.027 H -61.6 -40.3 2.0 0.027 0.0 BEZ
HOH
 9.151
8.571
 N
CA
 O1
O
GLY C:74 C:94 1.0 0.013 H -57.1 -36.2 1.0 0.013 0.0 HOH
 6.565
 O
 O
GLY D:74 D:94 0.0 0.0 H -72.9 -44.6 NA NA NA
GLY E:74 E:94 1.0 0.013 H -49.3 -54.8 NA NA NA
GLY F:74 F:94 3.0 0.04 H -62.2 -21.8 NA NA NA
GLY G:74 G:94 1.0 0.013 H -74.3 -41.4 NA NA NA
GLY H:74 H:94 2.0 0.027 H -53.2 -47.1 NA NA NA
GLY I:74 I:94 3.0 0.04 H -59.8 -52.6 NA NA NA
GLY J:74 J:94 0.0 0.0 H -52.3 -34.0 NA NA NA
GLY K:74 K:94 3.0 0.04 H -63.9 -24.4 NA NA NA
GLY L:74 L:94 2.0 0.027 H -63.5 -41.9 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:74 A:1094 2.0 0.027 H -67.8 -36.4 2.0 0.027 0.0 HOH
 3.017
 O
 O
GLY B:74 B:2094 1.0 0.013 H -67.4 -37.7 1.0 0.013 0.0 HOH
 2.985
 O
 O
GLY C:74 C:3094 1.0 0.013 H -66.6 -47.5 1.0 0.013 0.0 HOH
 2.877
 O
 O
GLY D:74 D:4094 2.0 0.027 H -65.7 -36.4 NA NA NA
GLY E:74 E:5094 2.0 0.027 H -61.0 -38.1 NA NA NA
GLY F:74 F:6094 2.0 0.027 H -65.1 -49.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:74 A:1094 2.0 0.027 H -66.6 -40.5 2.0 0.027 0.0 NTJ
HOH
 9.738
2.871
 O
O
 C2
O
GLY B:74 B:2094 2.0 0.027 H -74.8 -42.2 2.0 0.027 0.0 NTJ
HOH
 9.502
3.095
 O
O
 C2
O
GLY C:74 C:3094 2.0 0.027 H -68.2 -45.4 2.0 0.027 0.0 NTJ
HOH
 9.633
2.913
 O
O
 C2
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:74 A:94 2.0 0.027 H -56.9 -48.4 2.0 0.027 0.0 HOH
 2.861
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:74 A:94 1.0 0.013 H -71.4 -43.0 1.0 0.013 0.0 HOH
 2.721
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:74 A:94 2.0 0.027 H -66.5 -42.0 2.0 0.027 0.0 HOH
 2.765
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:73 A:94 2.0 0.027 H -58.0 -49.1 2.0 0.027 0.0 IOD
IOD
HOH
 7.278
4.747
2.804
 O
O
O
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:71 A:1094 3.0 0.04 H -69.5 -45.0 3.0 0.04 0.0 WW2
HOH
 7.909
8.056
 N
C
 C4
O
GLY B:71 B:2094 2.0 0.027 H -69.5 -44.8 2.0 0.027 0.0 WW2
HOH
 8.448
9.039
 N
CA
 C3
O
GLY C:71 C:3094 2.0 0.027 H -70.1 -44.6 2.0 0.027 0.0 WW2
HOH
 9.990
4.951
 N
N
 C4
O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:72 A:94 2.0 0.027 H -76.7 -42.7 2.0 0.027 0.0 HOH
 2.922
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:94 A:94 1.0 0.013 H -62.4 -44.5
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 GLY A:95 A:95 1.0 0.013 H -61.2 -46.2