Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862680 . T A CCDS32450.1:NM_001025195.1:c.259Atg>Ttg_NP_001020366.1:p.87M>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 MET A:68 A:1086 9.0 0.049 E -97.1 155.9 9.0 0.049 0.0 SIA
HOH
 8.386
3.575
 N
CA
 O4
O
MET B:68 B:2086 9.0 0.049 E -101.4 150.5 9.0 0.049 0.0 SIA
HOH
 7.555
3.381
 N
CE
 O4
O
MET C:68 C:3086 9.0 0.049 E -101.4 150.4 9.0 0.049 0.0 HOH
 3.332
 CB
 O
MET D:68 D:4086 9.0 0.049 E -99.6 154.6 9.0 0.049 0.0 SIA
HOH
 7.631
3.640
 N
CA
 C11
O
MET E:68 E:5086 12.0 0.065 E -101.9 154.7 12.0 0.065 0.0 SIA
HOH
 7.740
3.364
 N
CE
 O1B
O
MET F:68 F:6086 10.0 0.054 E -93.2 154.2 10.0 0.054 0.0 HOH
 3.374
 CA
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 MET A:68 A:1086 7.0 0.038 B -102.0 142.9 7.0 0.038 0.0 SIA
HOH
 8.241
3.041
 N
CA
 O1B
O
MET B:68 B:2086 11.0 0.059 E -93.4 152.0 11.0 0.059 0.0 SIA
HOH
 7.174
3.001
 N
CA
 O1B
O
MET C:68 C:3086 10.0 0.054 E -99.1 146.6 10.0 0.054 0.0 HOH
 3.249
 CE
 O
MET D:68 D:4086 9.0 0.049 E -93.4 150.1 NA NA NA
MET E:68 E:5086 10.0 0.054 E -91.4 153.6 NA NA NA
MET F:68 F:6086 9.0 0.049 E -99.8 145.1 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 MET A:68 A:1086 10.0 0.054 E -104.9 147.5 10.0 0.054 0.0 HOH
 3.416
 CE
 O
MET B:68 B:2086 14.0 0.076 E -94.6 149.6 14.0 0.076 0.0 HOH
 3.444
 CA
 O
MET C:68 C:3086 10.0 0.054 B -115.3 149.1 10.0 0.054 0.0 HOH
 4.474
 N
 O
MET D:68 D:4086 11.0 0.059 E -109.8 149.5 11.0 0.059 0.0 HOH
 3.719
 CA
 O
MET E:68 E:5086 13.0 0.07 E -113.6 143.1 13.0 0.07 0.0 HOH
 3.148
 CA
 O
MET F:68 F:6086 11.0 0.059 E -94.9 143.8 11.0 0.059 0.0 HOH
 4.041
 SD
 O
MET G:68 G:1086 10.0 0.054 E -102.5 139.9 NA NA NA
MET H:68 H:2086 14.0 0.076 E -108.3 151.6 NA NA NA
MET I:68 I:3086 13.0 0.07 B -99.0 164.7 NA NA NA
MET J:68 J:4086 10.0 0.054 E -101.8 143.2 NA NA NA
MET K:68 K:5086 9.0 0.049 E -96.7 156.9 NA NA NA
MET L:68 L:6086 10.0 0.054 E -101.4 151.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:68 A:1086 8.0 0.043 E -107.2 147.9 8.0 0.043 0.0 SIA
HOH
 9.858
4.242
 N
SD
 O9
O
MET B:68 B:2086 9.0 0.049 E -107.5 146.6 9.0 0.049 0.0 SIA
HOH
 9.513
3.154
 N
CA
 O9
O
MET C:68 C:3086 7.0 0.038 E -107.9 146.7 7.0 0.038 0.0 SIA
HOH
 9.284
4.047
 N
CB
 O9
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:68 A:1086 13.0 0.07 B -105.3 150.8 13.0 0.07 0.0 SIA
HOH
 9.116
3.151
 N
CA
 O9
O
MET B:68 B:2086 13.0 0.07 E -104.2 144.4 13.0 0.07 0.0 SIA
HOH
 9.863
3.493
 N
CA
 O9
O
MET C:68 C:3086 8.0 0.043 E -97.0 151.6 8.0 0.043 0.0 SIA
HOH
 9.030
3.304
 N
CE
 O9
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:68 A:1086 13.0 0.07 E -95.0 148.4 13.0 0.07 0.0 SIA
TCH
HOH
 8.883
9.988
3.410
 N
SD
CA
 O10
C21
O
MET B:68 B:2086 13.0 0.07 E -95.8 147.5 13.0 0.07 0.0 SIA
HOH
 9.803
4.080
 N
N
 O9
O
MET C:68 C:3086 14.0 0.076 E -96.6 148.3 14.0 0.076 0.0 SIA
HOH
 8.892
3.169
 N
CA
 C9
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 MET A:68 A:1086 10.0 0.054 E -94.1 156.4 10.0 0.054 0.0 COA
HOH
 9.007
3.416
 SD
CE
 O9P
O
MET B:68 B:2086 9.0 0.049 E -101.8 147.5 9.0 0.049 0.0 COA
HOH
 9.042
3.420
 CE
CA
 O9P
O
MET C:68 C:3086 10.0 0.054 E -99.1 149.8 10.0 0.054 0.0 COA
HOH
 8.900
2.951
 CE
CE
 O9P
O
MET D:68 D:4086 9.0 0.049 E -97.5 155.5 9.0 0.049 0.0 SIA
COA
HOH
 7.322
9.067
3.321
 N
CE
CE
 O1B
O9P
O
MET E:68 E:5086 11.0 0.059 E -95.2 152.7 11.0 0.059 0.0 SIA
COA
HOH
 9.120
9.146
3.257
 N
SD
CE
 O4
O9P
O
MET F:68 F:6086 10.0 0.054 E -96.1 150.3 10.0 0.054 0.0 COA
HOH
 8.648
3.509
 CE
CA
 O9P
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:66 A:86 9.0 0.049 B -87.9 146.6 9.0 0.049 0.0 SIA
HOH
 8.622
3.434
 N
CB
 O10
O
MET B:66 B:86 8.0 0.043 B -101.9 143.0 8.0 0.043 0.0 SIA
HOH
 9.328
4.017
 N
N
 C9
O
MET C:66 C:86 6.0 0.032 B -98.9 144.9 6.0 0.032 0.0 SIA
HOH
 8.784
6.230
 N
O
 C9
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:66 A:86 13.0 0.07 E -103.9 150.5 13.0 0.07 0.0 SIA
HOH
 8.854
3.714
 N
CA
 O9
O
MET B:66 B:86 9.0 0.049 E -98.9 137.0 9.0 0.049 0.0 SIA
HOH
 9.140
2.824
 N
CE
 O9
O
MET C:66 C:86 5.0 0.027 E -88.9 145.7 5.0 0.027 0.0 SIA
HOH
 9.103
3.196
 N
CA
 O8
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:66 A:86 10.0 0.054 E -98.8 142.6 10.0 0.054 0.0 SIA
HOH
 9.089
3.994
 N
SD
 O10
O
MET B:66 B:86 10.0 0.054 E -93.2 143.4 10.0 0.054 0.0 SIA
HOH
 8.747
3.027
 N
CE
 O8
O
MET C:66 C:86 9.0 0.049 E -86.2 145.4 9.0 0.049 0.0 SIA
HOH
 8.971
2.925
 N
CA
 O8
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 MET A:66 A:86 9.0 0.049 E -105.6 146.6 9.0 0.049 0.0 SIA
HOH
 8.698
5.151
 N
C
 C11
O
MET B:66 B:86 10.0 0.054 B -100.2 142.8 10.0 0.054 0.0 SIA
HOH
 9.328
3.259
 N
C
 C9
O
MET C:66 C:86 6.0 0.032 E -81.5 140.2 6.0 0.032 0.0 SIA
HOH
 8.654
3.220
 N
CA
 O9
O
MET D:66 D:86 7.0 0.038 E -110.6 143.5 NA NA NA
MET E:66 E:86 13.0 0.07 B -94.0 146.1 NA NA NA
MET F:66 F:86 12.0 0.065 B -106.1 140.8 NA NA NA
MET G:66 G:86 11.0 0.059 B -102.2 139.6 NA NA NA
MET H:66 H:86 6.0 0.032 E -112.5 147.6 NA NA NA
MET I:66 I:86 15.0 0.081 B -100.5 151.2 NA NA NA
MET J:66 J:86 7.0 0.038 B -101.8 137.8 NA NA NA
MET K:66 K:86 9.0 0.049 E -109.5 149.1 NA NA NA
MET L:66 L:86 12.0 0.065 B -98.6 148.4 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 MET A:66 A:1086 12.0 0.065 E -105.5 146.1 12.0 0.065 0.0 HOH
 3.111
 CE
 O
MET B:66 B:2086 11.0 0.059 E -98.6 146.7 11.0 0.059 0.0 SIA
HOH
 8.713
2.990
 N
CE
 C9
O
MET C:66 C:3086 4.0 0.022 E -89.3 152.8 4.0 0.022 0.0 SIA
HOH
 9.512
3.206
 N
CA
 O9
O
MET D:66 D:4086 12.0 0.065 E -107.2 145.4 NA NA NA
MET E:66 E:5086 12.0 0.065 E -96.7 148.0 NA NA NA
MET F:66 F:6086 10.0 0.054 E -89.2 149.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 MET A:66 A:1086 11.0 0.059 E -106.6 149.2 11.0 0.059 0.0 SIA
HOH
 7.514
3.643
 N
CA
 O10
O
MET B:66 B:2086 9.0 0.049 E -100.2 143.0 9.0 0.049 0.0 SIA
HOH
 9.047
3.009
 N
CE
 O9
O
MET C:66 C:3086 10.0 0.054 E -91.7 154.1 10.0 0.054 0.0 HOH
 3.257
 CA
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 MET A:66 A:86 15.0 0.081 E -89.9 156.6 15.0 0.081 0.0 HOH
 3.343
 CA
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 MET A:66 A:86 7.0 0.038 E -80.8 148.9 7.0 0.038 0.0 HOH
 3.533
 CA
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 MET A:66 A:86 12.0 0.065 E -86.8 152.5 12.0 0.065 0.0 HOH
 3.213
 SD
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 MET A:65 A:86 12.0 0.065 E -97.8 149.8 12.0 0.065 0.0 IOD
IOD
HOH
 6.643
4.370
3.541
 SD
CE
CB
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 MET A:63 A:1086 12.0 0.065 E -112.1 128.8 12.0 0.065 0.0 HOH
 1.220
 CG
 O
MET B:63 B:2086 11.0 0.059 E -124.1 147.4 11.0 0.059 0.0 HOH
 2.776
 C
 O
MET C:63 C:3086 11.0 0.059 E -56.1 -175.0 11.0 0.059 0.0 HOH
 3.721
 N
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 MET A:64 A:86 4.0 0.022 E -101.5 162.6 4.0 0.022 0.0 HOH
 3.371
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 MET A:86 A:86 11.0 0.059 E -77.8 151.7
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 MET A:87 A:87 11.0 0.059 E -81.2 152.9