Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862701 . T A CCDS32450.1:NM_001025195.1:c.238Aat>Tat_NP_001020366.1:p.80N>Y Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ASN A:61 A:1079 106.0 0.662 E -74.8 106.7 106.0 0.662 0.0 NAG
SIA
HOH
 1.453
2.258
3.038
 ND2
O
N
 C1
O1B
O
ASN B:61 B:2079 95.0 0.594 E -81.7 118.9 95.0 0.594 0.0 NAG
SIA
HOH
 1.444
2.873
3.085
 ND2
O
O
 C1
O1B
O
ASN C:61 C:3079 107.0 0.669 E -75.9 111.3 107.0 0.669 0.0 NAG
NDG
HOH
 1.449
6.820
2.748
 ND2
ND2
N
 C1
C1
O
ASN D:61 D:4079 104.0 0.65 E -82.7 108.6 104.0 0.65 0.0 NAG
SIA
HOH
 1.450
2.600
3.235
 ND2
O
O
 C1
O1A
O
ASN E:61 E:5079 99.0 0.619 E -84.3 101.0 99.0 0.619 0.0 NAG
SIA
HOH
 1.453
2.162
2.810
 ND2
O
O
 C1
O10
O
ASN F:61 F:6079 109.0 0.681 E -77.8 112.1 109.0 0.681 0.0 NAG
NAG
HOH
 1.448
7.247
3.491
 ND2
ND2
O
 C1
C1
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASN A:61 A:1079 112.0 0.7 E -76.7 97.5 112.0 0.7 0.0 NAG
SIA
HOH
 1.450
2.395
4.669
 ND2
O
N
 C1
O4
O
ASN B:61 B:2079 102.0 0.637 E -75.0 116.6 102.0 0.637 0.0 NAG
SIA
HOH
 1.451
2.612
2.606
 ND2
O
CB
 C1
O4
O
ASN C:61 C:3079 101.0 0.631 E -82.8 114.7 101.0 0.631 0.0 NAG
HOH
 1.453
2.651
 ND2
N
 C1
O
ASN D:61 D:4079 115.0 0.719 E -76.2 104.3 NA NA NA
ASN E:61 E:5079 101.0 0.631 E -84.4 111.2 NA NA NA
ASN F:61 F:6079 110.0 0.688 E -82.5 92.8 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ASN A:61 A:1079 109.0 0.681 E -89.2 107.8 109.0 0.681 0.0 NAG
NAG
HOH
 2.648
6.475
5.655
 ND2
ND2
OD1
 O5
O5
O
ASN B:61 B:2079 91.0 0.569 E -70.6 111.1 91.0 0.569 0.0 NAG
HOH
 2.552
2.728
 ND2
O
 C1
O
ASN C:61 C:3079 99.0 0.619 E -60.6 94.1 99.0 0.619 0.0 NAG
HOH
 2.682
4.430
 OD1
N
 O5
O
ASN D:61 D:4079 95.0 0.594 E -80.4 118.3 95.0 0.594 0.0 NAG
HOH
 2.882
2.483
 CG
ND2
 C1
O
ASN E:61 E:5079 93.0 0.581 E -81.3 108.6 93.0 0.581 0.0 NAG
HOH
 2.676
3.104
 ND2
CG
 O5
O
ASN F:61 F:6079 102.0 0.637 E -86.6 89.2 102.0 0.637 0.0 NAG
HOH
 2.801
2.569
 ND2
O
 O5
O
ASN G:61 G:1079 97.0 0.606 E -68.1 109.2 NA NA NA
ASN H:61 H:2079 95.0 0.594 -84.6 78.3 NA NA NA
ASN I:61 I:3079 103.0 0.644 E -68.8 85.7 NA NA NA
ASN J:61 J:4079 83.0 0.519 E -86.0 113.3 NA NA NA
ASN K:61 K:5079 109.0 0.681 E -65.1 110.8 NA NA NA
ASN L:61 L:6079 103.0 0.644 E -80.3 113.6 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:61 A:1079 106.0 0.662 E -85.0 100.4 106.0 0.662 0.0 NAG
SIA
HOH
 1.447
2.809
5.741
 ND2
O
N
 C1
O6
O
ASN B:61 B:2079 106.0 0.662 E -84.2 101.8 106.0 0.662 0.0 NAG
SIA
HOH
 1.452
2.445
4.541
 ND2
O
OD1
 C1
O2
O
ASN C:61 C:3079 105.0 0.656 E -84.5 99.4 105.0 0.656 0.0 NAG
SIA
HOH
 1.450
2.819
2.520
 ND2
O
ND2
 C1
O6
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:61 A:1079 111.0 0.694 E -90.7 114.3 111.0 0.694 0.0 NAG
SIA
HOH
 1.452
3.032
2.946
 ND2
ND2
O
 C1
O1A
O
ASN B:61 B:2079 113.0 0.706 E -75.3 109.9 113.0 0.706 0.0 NAG
SIA
HOH
 1.455
2.473
4.806
 ND2
O
N
 C1
O2
O
ASN C:61 C:3079 118.0 0.738 E -71.8 108.3 118.0 0.738 0.0 NAG
SIA
HOH
 1.457
2.625
3.008
 ND2
O
CB
 C1
O2
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:61 A:1079 102.0 0.637 E -84.5 113.1 102.0 0.637 0.0 NAG
SIA
HOH
 1.449
2.759
3.489
 ND2
O
ND2
 C1
O7
O
ASN B:61 B:2079 104.0 0.65 E -84.2 113.4 104.0 0.65 0.0 NAG
SIA
HOH
 1.442
2.181
3.030
 ND2
O
O
 C1
O2
O
ASN C:61 C:3079 100.0 0.625 E -84.1 112.6 100.0 0.625 0.0 NAG
SIA
HOH
 1.440
2.564
4.822
 ND2
O
O
 C1
O2
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ASN A:61 A:1079 111.0 0.694 E -78.7 120.1 111.0 0.694 0.0 NAG
NAG
HOH
 1.449
6.663
2.943
 ND2
ND2
N
 C1
C1
O
ASN B:61 B:2079 105.0 0.656 E -78.5 116.3 105.0 0.656 0.0 NAG
HOH
 1.452
2.725
 ND2
O
 C1
O
ASN C:61 C:3079 107.0 0.669 E -80.1 107.3 107.0 0.669 0.0 NAG
HOH
 1.450
2.473
 ND2
OD1
 C1
O
ASN D:61 D:4079 105.0 0.656 E -80.2 117.4 105.0 0.656 0.0 NAG
SIA
HOH
 1.450
3.544
2.936
 ND2
O
N
 C1
O10
O
ASN E:61 E:5079 105.0 0.656 E -77.3 103.2 90.0 0.562 0.094 D:P23141:0.094
 NAG
SIA
HOH
 1.454
3.366
2.716
 ND2
O
N
 C1
O1B
O
ASN F:61 F:6079 100.0 0.625 E -78.8 109.7 100.0 0.625 0.0 NAG
NAG
HOH
 1.450
6.674
2.928
 ND2
ND2
O
 C1
C1
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:59 A:79 106.0 0.662 E -85.8 93.5 106.0 0.662 0.0 NAG
SIA
HOH
 1.451
2.803
3.857
 ND2
O
ND2
 C1
O7
O
ASN B:59 B:79 105.0 0.656 E -87.4 86.4 105.0 0.656 0.0 NAG
SIA
HOH
 1.448
2.273
4.422
 ND2
O
N
 C1
O2
O
ASN C:59 C:79 104.0 0.65 E -88.3 89.9 104.0 0.65 0.0 NAG
SIA
HOH
 1.448
2.446
4.516
 ND2
O
O
 C1
O2
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:59 A:79 104.0 0.65 E -87.3 110.2 104.0 0.65 0.0 NAG
SIA
HOH
 1.448
2.787
3.045
 ND2
N
ND2
 C1
O1B
O
ASN B:59 B:79 103.0 0.644 E -79.4 89.0 103.0 0.644 0.0 NAG
SIA
HOH
 1.454
2.288
3.001
 ND2
O
O
 C1
O2
O
ASN C:59 C:79 109.0 0.681 E -79.7 99.9 109.0 0.681 0.0 NAG
SIA
HOH
 1.447
3.269
3.039
 ND2
CB
O
 C1
O1A
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:59 A:79 105.0 0.656 E -78.4 101.5 105.0 0.656 0.0 NAG
SIA
HOH
 1.448
3.025
2.648
 ND2
O
O
 C1
O2
O
ASN B:59 B:79 104.0 0.65 E -80.5 107.0 104.0 0.65 0.0 NAG
SIA
HOH
 1.451
2.438
3.263
 ND2
O
O
 C1
O2
O
ASN C:59 C:79 109.0 0.681 E -74.2 101.4 109.0 0.681 0.0 SIA
NAG
HOH
 3.096
1.454
2.661
 O
ND2
ND2
 O7
C1
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ASN A:59 A:79 108.0 0.675 E -84.0 88.4 108.0 0.675 0.0 NAG
SIA
HOH
 1.452
2.365
2.922
 ND2
O
N
 C1
O7
O
ASN B:59 B:79 110.0 0.688 -72.1 61.0 110.0 0.688 0.0 NAG
SIA
 1.448
2.690
 ND2
O
 C1
O2
ASN C:59 C:79 109.0 0.681 E -81.1 115.5 109.0 0.681 0.0 SIA
NAG
HOH
 3.349
1.446
6.046
 O
ND2
O
 C1
C1
O
ASN D:59 D:79 100.0 0.625 E -89.3 136.8 NA NA NA
ASN E:59 E:79 110.0 0.688 E -77.0 74.6 NA NA NA
ASN F:59 F:79 124.0 0.775 E -57.9 129.0 NA NA NA
ASN G:59 G:79 112.0 0.7 E -61.8 81.9 NA NA NA
ASN H:59 H:79 116.0 0.725 E -66.7 87.6 NA NA NA
ASN I:59 I:79 131.0 0.819 E -52.6 105.0 NA NA NA
ASN J:59 J:79 115.0 0.719 E -65.9 71.0 NA NA NA
ASN K:59 K:79 105.0 0.656 E -65.7 91.9 NA NA NA
ASN L:59 L:79 130.0 0.812 E -62.5 88.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASN A:59 A:1079 107.0 0.669 E -83.4 104.1 107.0 0.669 0.0 NAG
SIA
HOH
 1.461
2.947
3.130
 ND2
N
ND2
 C1
C11
O
ASN B:59 B:2079 103.0 0.644 E -86.2 92.0 103.0 0.644 0.0 NAG
SIA
HOH
 1.458
2.338
2.698
 ND2
O
O
 C1
O2
O
ASN C:59 C:3079 115.0 0.719 E -65.6 110.5 115.0 0.719 0.0 NAG
SIA
HOH
 1.455
2.869
2.786
 ND2
CB
ND2
 C1
O2
O
ASN D:59 D:4079 111.0 0.694 E -81.7 101.1 NA NA NA
ASN E:59 E:5079 103.0 0.644 E -85.5 98.7 NA NA NA
ASN F:59 F:6079 115.0 0.719 E -72.2 109.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ASN A:59 A:1079 105.0 0.656 E -90.4 110.4 105.0 0.656 0.0 NAG
SIA
HOH
 1.449
3.169
3.094
 ND2
O
OD1
 C1
O1B
O
ASN B:59 B:2079 106.0 0.662 E -84.6 94.5 106.0 0.662 0.0 NAG
SIA
HOH
 1.456
2.170
2.676
 ND2
O
O
 C1
O2
O
ASN C:59 C:3079 106.0 0.662 E -80.9 89.3 106.0 0.662 0.0 NAG
SIA
HOH
 1.452
2.429
2.820
 ND2
O
N
 C1
O2
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ASN A:59 A:79 113.0 0.706 E -67.3 116.4 113.0 0.706 0.0 NAG
SCN
HOH
 1.429
7.986
2.673
 ND2
N
O
 C1
N
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ASN A:59 A:79 108.0 0.675 E -79.5 101.2 108.0 0.675 0.0 NAG
HOH
 1.452
2.899
 ND2
N
 C1
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ASN A:59 A:79 101.0 0.631 E -80.7 113.3 101.0 0.631 0.0 NAG
HOH
 1.456
2.667
 ND2
O
 C1
O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLN A:58 A:79 123.0 0.683 E -75.2 115.9 123.0 0.683 0.0 IOD
IOD
HOH
 6.366
9.949
2.712
 N
N
O
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ASN A:56 A:1079 114.0 0.713 E -96.3 79.8 114.0 0.713 0.0 HOH
 6.135
 N
 O
ASN B:56 B:2079 103.0 0.644 E -73.3 114.2 103.0 0.644 0.0 HOH
 5.084
 O
 O
ASN C:56 C:3079 103.0 0.644 E -72.8 113.1 103.0 0.644 0.0 HOH
 3.032
 ND2
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ASN A:57 A:79 110.0 0.688 E -66.4 116.7 110.0 0.688 0.0 NAG
NAG
HOH
 1.463
6.688
3.017
 ND2
ND2
ND2
 C1
C1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ASN A:79 A:79 95.0 0.594 E -79.0 110.5
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ASN A:80 A:80 104.0 0.65 E -76.7 104.7