Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862703 . T A CCDS32450.1:NM_001025195.1:c.236aAg>aTg_NP_001020366.1:p.79K>M Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 LYS A:60 A:1078 71.0 0.355 E -89.0 122.3 35.0 0.175 0.18 B:P23141:0.18
 NAG
SIA
HOH
 7.111
4.449
2.936
 C
CD
NZ
 C8
O2
O
LYS B:60 B:2078 73.0 0.365 E -87.9 126.3 35.0 0.175 0.19 C:P23141:0.19
 NAG
SIA
HOH
 6.274
3.227
2.893
 C
CG
NZ
 C1
C9
O
LYS C:60 C:3078 70.0 0.35 E -86.6 125.1 33.0 0.165 0.185 A:P23141:0.185
 NAG
HOH
 7.118
2.556
 C
NZ
 C8
O
LYS D:60 D:4078 74.0 0.37 E -87.9 129.7 39.0 0.195 0.175 E:P23141:0.175
 NAG
SIA
HOH
 7.188
3.661
2.900
 C
C
NZ
 C8
O1A
O
LYS E:60 E:5078 70.0 0.35 E -85.5 130.5 36.0 0.18 0.17 F:P23141:0.17
 NAG
SIA
HOH
 6.504
3.041
2.490
 C
CD
NZ
 O5
O4
O
LYS F:60 F:6078 70.0 0.35 E -81.8 127.8 34.0 0.17 0.18 D:P23141:0.18
 NAG
HOH
 7.203
2.966
 C
NZ
 C1
O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LYS A:60 A:1078 68.0 0.34 E -85.4 125.3 33.0 0.165 0.175 B:P23141:0.175
 NAG
SIA
HOH
 7.037
4.411
2.887
 C
NZ
NZ
 C1
O8
O
LYS B:60 B:2078 71.0 0.355 E -87.0 121.9 33.0 0.165 0.19 C:P23141:0.19
 NAG
SIA
HOH
 6.872
5.006
2.964
 C
CG
NZ
 C5
N5
O
LYS C:60 C:3078 70.0 0.35 E -79.5 133.3 35.0 0.175 0.175 A:P23141:0.175
 NAG
HOH
 7.173
2.606
 C
NZ
 O7
O
LYS D:60 D:4078 70.0 0.35 E -90.5 126.4 NA NA NA
LYS E:60 E:5078 74.0 0.37 E -76.7 133.8 NA NA NA
LYS F:60 F:6078 74.0 0.37 E -75.2 125.2 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LYS A:60 A:1078 66.0 0.33 E -81.3 136.9 33.0 0.165 0.165 B:P23141:0.165
 NAG
HOH
 7.170
5.340
 C
CE
 O7
O
LYS B:60 B:2078 72.0 0.36 E -77.4 114.6 36.0 0.18 0.18 C:P23141:0.18
 NAG
HOH
 7.672
2.484
 C
NZ
 C1
O
LYS C:60 C:3078 78.0 0.39 E -68.7 103.5 41.0 0.205 0.185 A:P23141:0.185
 NAG
HOH
 5.299
2.951
 C
NZ
 C8
O
LYS D:60 D:4078 67.0 0.335 E -77.0 124.6 34.0 0.17 0.165 E:P23141:0.165
 NAG
HOH
 4.195
5.849
 C
CE
 C8
O
LYS E:60 E:5078 78.0 0.39 E -72.4 109.3 38.0 0.19 0.2 F:P23141:0.2
 NAG
HOH
 8.003
5.780
 C
N
 C1
O
LYS F:60 F:6078 76.0 0.38 E -73.3 131.3 38.0 0.19 0.19 D:P23141:0.19
 NAG
HOH
 5.120
6.006
 C
N
 C8
O
LYS G:60 G:1078 69.0 0.345 E -84.5 114.1 NA NA NA
LYS H:60 H:2078 75.0 0.375 E -82.2 125.5 NA NA NA
LYS I:60 I:3078 80.0 0.4 E -97.5 121.2 NA NA NA
LYS J:60 J:4078 64.0 0.32 E -88.0 130.4 NA NA NA
LYS K:60 K:5078 69.0 0.345 E -93.4 112.2 NA NA NA
LYS L:60 L:6078 71.0 0.355 E -78.2 123.7 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:60 A:1078 83.0 0.415 E -92.2 129.3 41.0 0.205 0.21 B:P23141:0.21
 NAG
SIA
HOH
 6.366
2.837
3.377
 C
CG
NZ
 C1
O1B
O
LYS B:60 B:2078 85.0 0.425 E -92.3 128.1 39.0 0.195 0.23 C:P23141:0.23
 NAG
SIA
HOH
 6.300
3.316
5.295
 C
CG
CA
 C1
O1B
O
LYS C:60 C:3078 82.0 0.41 E -93.2 129.5 41.0 0.205 0.205 A:P23141:0.205
 NAG
SIA
HOH
 6.039
3.754
5.904
 C
CG
N
 C1
O1B
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:60 A:1078 76.0 0.38 E -87.3 130.7 40.0 0.2 0.18 B:P23141:0.18
 NAG
SIA
HOH
 5.984
4.656
3.053
 C
C
NZ
 C1
O1B
O
LYS B:60 B:2078 77.0 0.385 E -87.9 118.9 36.0 0.18 0.205 C:P23141:0.205
 NAG
SIA
HOH
 6.511
3.167
2.933
 C
CG
NZ
 C1
O1B
O
LYS C:60 C:3078 73.0 0.365 E -102.0 121.0 37.0 0.185 0.18 A:P23141:0.18
 NAG
SIA
HOH
 6.561
3.196
2.764
 C
CG
NZ
 C1
O1B
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:60 A:1078 81.0 0.405 E -88.8 126.3 39.0 0.195 0.21 B:P23141:0.21
 NAG
SIA
HOH
 6.188
4.271
3.102
 C
CG
CD
 C1
O7
O
LYS B:60 B:2078 86.0 0.43 E -87.7 125.1 40.0 0.2 0.23 C:P23141:0.23
 NAG
SIA
HOH
 6.407
2.824
2.775
 C
CG
NZ
 C1
O1B
O
LYS C:60 C:3078 83.0 0.415 E -89.0 125.3 40.0 0.2 0.215 A:P23141:0.215
 NAG
SIA
HOH
 6.446
2.909
3.495
 C
NZ
CD
 C1
O1B
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:60 A:1078 70.0 0.35 E -79.7 127.3 36.0 0.18 0.17 B:P23141:0.17
 NAG
HOH
 7.199
2.816
 C
NZ
 O7
O
LYS B:60 B:2078 70.0 0.35 E -85.1 130.0 34.0 0.17 0.18 C:P23141:0.18
 NAG
HOH
 6.777
2.769
 C
NZ
 O7
O
LYS C:60 C:3078 70.0 0.35 E -84.5 128.9 33.0 0.165 0.185 A:P23141:0.185
 NAG
HOH
 6.886
2.751
 C
NZ
 C1
O
LYS D:60 D:4078 68.0 0.34 E -84.5 129.6 34.0 0.17 0.17 F:P23141:0.17
 NAG
SIA
HOH
 7.219
2.981
3.165
 C
CG
NZ
 C1
O10
O
LYS E:60 E:5078 71.0 0.355 E -81.1 125.7 34.0 0.17 0.185 D:P23141:0.185
 NAG
SIA
HOH
 6.662
3.288
2.635
 C
CD
NZ
 C8
O1A
O
LYS F:60 F:6078 68.0 0.34 E -79.7 126.9 35.0 0.175 0.165 E:P23141:0.165
 NAG
HOH
 6.236
2.695
 C
NZ
 C8
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:58 A:78 83.0 0.415 E -75.2 132.7 44.0 0.22 0.195 B:P23141:0.195
 NAG
SIA
HOH
 6.549
4.208
2.796
 C
CG
NZ
 O5
O7
O
LYS B:58 B:78 81.0 0.405 E -76.4 133.1 39.0 0.195 0.21 C:P23141:0.21
 NAG
SIA
HOH
 6.387
2.983
2.978
 C
CG
NZ
 C1
O1B
O
LYS C:58 C:78 82.0 0.41 E -77.6 131.6 43.0 0.215 0.195 A:P23141:0.195
 NAG
SIA
HOH
 6.436
3.021
3.957
 C
NZ
CD
 C1
O1B
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:58 A:78 74.0 0.37 E -90.0 135.8 40.0 0.2 0.17 B:P23141:0.17
 NAG
SIA
HOH
 6.252
3.842
5.084
 C
CG
CE
 C1
O1B
O
LYS B:58 B:78 75.0 0.375 E -89.9 125.8 38.0 0.19 0.185 C:P23141:0.185
 NAG
SIA
HOH
 6.271
2.972
4.967
 C
CG
NZ
 C8
O1B
O
LYS C:58 C:78 76.0 0.38 E -93.1 125.0 40.0 0.2 0.18 A:P23141:0.18
 NAG
SIA
HOH
 6.397
4.093
2.663
 C
CG
NZ
 C1
O1B
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:58 A:78 76.0 0.38 E -88.8 129.6 40.0 0.2 0.18 B:P23141:0.18
 NAG
SIA
HOH
 6.412
4.356
3.255
 C
CG
NZ
 O5
O7
O
LYS B:58 B:78 77.0 0.385 E -84.9 129.1 37.0 0.185 0.2 C:P23141:0.2
 NAG
SIA
HOH
 6.378
3.765
3.941
 C
CG
CA
 C1
O1B
O
LYS C:58 C:78 77.0 0.385 E -91.7 124.1 38.0 0.19 0.195 A:P23141:0.195
 SIA
NAG
HOH
 3.970
6.512
3.620
 CG
C
CA
 O9
C1
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:58 A:78 94.0 0.47 E -77.7 128.8 47.0 0.235 0.235 B:P23141:0.235
 NAG
SIA
HOH
 6.372
4.375
3.091
 C
CG
NZ
 C1
C9
O
LYS B:58 B:78 77.0 0.385 E -68.8 112.0 41.0 0.205 0.18 C:P23141:0.18
 NAG
SIA
HOH
 6.326
2.866
5.383
 C
CG
NZ
 C8
O1B
O
LYS C:58 C:78 89.0 0.445 E -73.5 124.3 44.0 0.22 0.225 A:P23141:0.225
 SIA
NAG
HOH
 3.895
6.472
7.523
 CG
C
CE
 O1B
C1
O
LYS D:58 D:78 92.0 0.46 E -82.2 120.9 NA NA NA
LYS E:58 E:78 78.0 0.39 E -77.8 120.6 NA NA NA
LYS F:58 F:78 80.0 0.4 E -90.9 111.4 NA NA NA
LYS G:58 G:78 83.0 0.415 E -108.5 111.2 NA NA NA
LYS H:58 H:78 88.0 0.44 E -86.8 121.6 NA NA NA
LYS I:58 I:78 77.0 0.385 E -81.0 99.2 NA NA NA
LYS J:58 J:78 87.0 0.435 E -80.3 115.4 NA NA NA
LYS K:58 K:78 97.0 0.485 E -84.7 104.7 NA NA NA
LYS L:58 L:78 78.0 0.39 E -81.0 106.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LYS A:58 A:1078 69.0 0.345 E -86.2 131.6 36.0 0.18 0.165 B:Q9UK77:0.165
 NAG
SIA
HOH
 5.926
3.448
3.002
 C
CG
NZ
 O5
O10
O
LYS B:58 B:2078 68.0 0.34 E -80.7 127.5 33.0 0.165 0.175 C:Q9UK77:0.175
 NAG
SIA
HOH
 5.413
3.430
2.714
 C
CG
NZ
 C1
O1B
O
LYS C:58 C:3078 73.0 0.365 E -91.4 117.7 36.0 0.18 0.185 A:Q9UK77:0.185
 NAG
SIA
HOH
 6.590
4.365
3.947
 C
CG
CA
 C1
O1B
O
LYS D:58 D:4078 63.0 0.315 E -94.7 131.1 NA NA NA
LYS E:58 E:5078 71.0 0.355 E -85.5 130.7 NA NA NA
LYS F:58 F:6078 66.0 0.33 E -91.2 121.0 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LYS A:58 A:1078 69.0 0.345 E -75.2 138.0 34.0 0.17 0.175 B:Q9UK77:0.175
 NAG
SIA
HOH
 5.790
3.986
3.043
 C
CD
NZ
 O6
O8
O
LYS B:58 B:2078 69.0 0.345 E -89.5 133.9 35.0 0.175 0.17 C:Q9UK77:0.17
 NAG
SIA
HOH
 5.787
3.169
2.719
 C
CG
NZ
 C1
O1B
O
LYS C:58 C:3078 72.0 0.36 E -86.8 126.2 33.0 0.165 0.195 A:Q9UK77:0.195
 NAG
SIA
HOH
 6.492
3.117
3.769
 C
NZ
C
 O5
O1B
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 LYS A:58 A:78 69.0 0.345 E -92.2 127.8 35.0 0.175 0.17 A:P23141:0.17
 NAG
SCN
HOH
 7.166
5.689
3.896
 C
NZ
CA
 C1
N
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 LYS A:58 A:78 72.0 0.36 E -79.3 125.7 37.0 0.185 0.175 A:P23141-3:0.175
 NAG
HOH
 7.269
3.279
 C
NZ
 C1
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LYS A:58 A:78 67.0 0.335 E -80.9 130.1 67.0 0.335 0.0 NAG
HOH
 6.990
2.928
 C
NZ
 C8
O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LYS A:57 A:78 67.0 0.335 E -75.7 134.0 67.0 0.335 0.0 IOD
IOD
HOH
 4.487
6.657
5.379
 N
NZ
NZ
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 LYS A:55 A:1078 52.0 0.26 E -81.8 134.4 39.0 0.195 0.065 B:P23141:0.065
 HOH
 4.574
 CA
 O
LYS B:55 B:2078 64.0 0.32 E -90.8 118.6 38.0 0.19 0.13 C:P23141:0.13
 HOH
 5.731
 CE
 O
LYS C:55 C:3078 51.0 0.255 E -90.5 119.0 33.0 0.165 0.09 A:P23141:0.09
 HOH
 4.839
 NZ
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 LYS A:56 A:78 56.0 0.28 E -80.3 119.2 56.0 0.28 0.0 NAG
HOH
 6.816
2.800
 C
NZ
 C8
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 LYS A:78 A:78 74.0 0.37 E -73.0 128.6
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 LYS A:79 A:79 51.0 0.255 E -74.1 124.1