Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862712 . C A CCDS32450.1:NM_001025195.1:c.227aGc>aTc_NP_001020366.1:p.76S>I Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 SER A:57 A:1075 91.0 0.791 S -99.5 170.4 39.0 0.339 0.452 B:P23141:0.452
 HOH
 3.137
 N
 O
SER B:57 B:2075 87.0 0.757 S -99.5 163.3 31.0 0.27 0.487 C:P23141:0.487
 SIA
HOH
 8.448
2.621
 O
O
 O9
O
SER C:57 C:3075 110.0 0.957 S -80.6 -39.3 50.0 0.435 0.522 A:P23141:0.522
 HOH
 2.577
 OG
 O
SER D:57 D:4075 91.0 0.791 S -94.9 167.6 40.0 0.348 0.443 E:P23141:0.443
 SIA
HOH
 8.924
2.533
 O
O
 O1A
O
SER E:57 E:5075 96.0 0.835 S -91.4 157.5 35.0 0.304 0.531 F:P23141:0.53
 SIA
HOH
 8.092
2.594
 O
O
 C11
O
SER F:57 F:6075 111.0 0.965 S -75.6 -45.2 48.0 0.417 0.548 D:P23141:0.548
 HOH
 2.382
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 SER A:57 A:1075 92.0 0.8 S -93.8 168.4 32.0 0.278 0.522 B:P23141:0.522
 SIA
HOH
 9.521
2.661
 O
O
 C11
O
SER B:57 B:2075 109.0 0.948 S -65.5 -58.9 46.0 0.4 0.548 C:P23141:0.548
 HOH
 2.714
 N
 O
SER C:57 C:3075 108.0 0.939 S -80.1 -17.8 41.0 0.357 0.582 A:P23141:0.583
 HOH
 2.479
 O
 O
SER D:57 D:4075 92.0 0.8 S -83.2 157.6 NA NA NA
SER E:57 E:5075 107.0 0.93 S -83.7 -29.7 NA NA NA
SER F:57 F:6075 109.0 0.948 S -77.6 -46.8 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 SER A:57 A:1075 110.0 0.957 S -75.0 -39.0 47.0 0.409 0.548 B:P23141:0.548
 HOH
 2.675
 O
 O
SER B:57 B:2075 106.0 0.922 S -78.9 -41.9 45.0 0.391 0.531 C:P23141:0.53
 HOH
 3.237
 O
 O
SER C:57 C:3075 111.0 0.965 S -86.3 -17.9 49.0 0.426 0.539 A:P23141:0.539
 NAG
HOH
 9.405
6.062
 C
C
 C8
O
SER D:57 D:4075 93.0 0.809 S -95.7 152.0 33.0 0.287 0.522 E:P23141:0.522
 NAG
HOH
 7.747
2.773
 O
N
 C8
O
SER E:57 E:5075 104.0 0.904 S -90.9 -28.2 39.0 0.339 0.565 F:P23141:0.565
 HOH
 2.802
 N
 O
SER F:57 F:6075 114.0 0.991 S -78.1 -38.2 51.0 0.443 0.548 D:P23141:0.548
 NAG
HOH
 9.834
2.425
 C
O
 C8
O
SER G:57 G:1075 99.0 0.861 S -103.5 161.2 NA NA NA
SER H:57 H:2075 93.0 0.809 -111.4 153.8 NA NA NA
SER I:57 I:3075 98.0 0.852 S -77.2 148.9 NA NA NA
SER J:57 J:4075 102.0 0.887 S -74.6 -69.8 NA NA NA
SER K:57 K:5075 94.0 0.817 -76.2 173.4 NA NA NA
SER L:57 L:6075 107.0 0.93 S -94.4 -46.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:57 A:1075 110.0 0.957 S -76.3 -29.0 42.0 0.365 0.592 B:P23141:0.591
 SIA
HOH
 9.025
2.436
 N
OG
 O1A
O
SER B:57 B:2075 112.0 0.974 S -75.7 -30.4 46.0 0.4 0.574 C:P23141:0.574
 SIA
HOH
 9.950
2.831
 N
N
 O1B
O
SER C:57 C:3075 111.0 0.965 S -75.7 -29.4 47.0 0.409 0.556 A:P23141:0.557
 HOH
 2.566
 N
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:57 A:1075 108.0 0.939 S -78.7 -46.1 46.0 0.4 0.539 B:P23141:0.539
 HOH
 2.692
 O
 O
SER B:57 B:2075 109.0 0.948 S -84.9 -25.5 45.0 0.391 0.557 C:P23141:0.557
 SIA
HOH
 9.505
3.118
 N
N
 O1B
O
SER C:57 C:3075 112.0 0.974 S -67.7 -74.0 47.0 0.409 0.565 A:P23141:0.565
 HOH
 2.542
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:57 A:1075 110.0 0.957 S -72.8 -32.0 42.0 0.365 0.592 B:P23141:0.591
 HOH
 3.417
 O
 O
SER B:57 B:2075 110.0 0.957 S -74.2 -33.3 45.0 0.391 0.566 C:P23141:0.565
 SIA
HOH
 9.365
2.717
 N
N
 O1B
O
SER C:57 C:3075 113.0 0.983 S -74.0 -32.6 48.0 0.417 0.566 A:P23141:0.565
 SIA
HOH
 9.100
2.708
 N
N
 O1A
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:57 A:1075 93.0 0.809 S -89.0 165.0 39.0 0.339 0.47 B:P23141:0.47
 HOH
 2.556
 O
 O
SER B:57 B:2075 92.0 0.8 S -93.9 160.2 36.0 0.313 0.487 C:P23141:0.487
 HOH
 2.504
 O
 O
SER C:57 C:3075 91.0 0.791 S -94.2 162.0 35.0 0.304 0.487 A:P23141:0.487
 HOH
 2.531
 O
 O
SER D:57 D:4075 87.0 0.757 S -95.2 166.8 33.0 0.287 0.47 F:P23141:0.47
 SIA
HOH
 9.400
2.507
 O
O
 O10
O
SER E:57 E:5075 90.0 0.783 S -89.8 166.0 33.0 0.287 0.496 D:P23141:0.496
 HOH
 2.610
 O
 O
SER F:57 F:6075 92.0 0.8 S -93.1 165.0 33.0 0.287 0.513 E:P23141:0.513
 HOH
 2.627
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:55 A:75 111.0 0.965 S -85.1 -43.4 47.0 0.409 0.556 B:P23141:0.557
 HOH
 3.256
 N
 O
SER B:55 B:75 112.0 0.974 S -91.7 -36.7 45.0 0.391 0.583 C:P23141:0.583
 SIA
HOH
 9.167
2.805
 N
N
 O1B
O
SER C:55 C:75 111.0 0.965 S -89.3 -40.2 46.0 0.4 0.565 A:P23141:0.565
 SIA
HOH
 9.240
2.765
 N
N
 O1B
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:55 A:75 112.0 0.974 S -72.0 -22.9 45.0 0.391 0.583 B:P23141:0.583
 HOH
 2.887
 N
 O
SER B:55 B:75 116.0 1.0 S -61.5 -46.8 46.0 0.4 0.6 C:P23141:0.609
 SIA
HOH
 9.681
2.725
 N
N
 O1B
O
SER C:55 C:75 111.0 0.965 S -85.1 -39.3 50.0 0.435 0.53 A:P23141:0.53
 HOH
 2.640
 N
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:55 A:75 109.0 0.948 S -79.5 -31.5 45.0 0.391 0.557 B:P23141:0.557
 HOH
 2.765
 O
 O
SER B:55 B:75 113.0 0.983 S -74.1 -33.3 45.0 0.391 0.592 C:P23141:0.591
 HOH
 2.918
 N
 O
SER C:55 C:75 111.0 0.965 S -74.6 -30.2 46.0 0.4 0.565 A:P23141:0.565
 HOH
 2.888
 N
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:55 A:75 112.0 0.974 S -83.6 -4.8 42.0 0.365 0.609 B:P23141:0.609
 HOH
 2.939
 N
 O
SER B:55 B:75 116.0 1.0 S -73.3 -35.5 47.0 0.409 0.591 C:P23141:0.6
 SIA
HOH
 9.402
3.657
 N
CB
 O1B
O
SER C:55 C:75 112.0 0.974 S -101.0 -11.8 47.0 0.409 0.565 A:P23141:0.565
 HOH
 7.492
 OG
 O
SER D:55 D:75 115.0 1.0 S -90.2 22.5 NA NA NA
SER E:55 E:75 115.0 1.0 S -82.5 -38.1 NA NA NA
SER F:55 F:75 109.0 0.948 -84.7 -87.6 NA NA NA
SER G:55 G:75 111.0 0.965 S -77.9 -71.3 NA NA NA
SER H:55 H:75 113.0 0.983 S -86.2 -15.2 NA NA NA
SER I:55 I:75 102.0 0.887 S -83.9 -88.5 NA NA NA
SER J:55 J:75 114.0 0.991 S -82.0 -17.6 NA NA NA
SER K:55 K:75 108.0 0.939 S -86.8 18.7 NA NA NA
SER L:55 L:75 103.0 0.896 S -77.5 -105.4 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 SER A:55 A:1075 91.0 0.791 S -101.3 162.7 38.0 0.33 0.461 B:Q9UK77:0.461
 NAG
SIA
HOH
 9.456
7.333
3.112
 O
O
N
 C6
O10
O
SER B:55 B:2075 92.0 0.8 S -96.0 164.0 31.0 0.27 0.53 C:Q9UK77:0.53
 NAG
SIA
HOH
 9.523
7.786
2.566
 O
O
O
 N2
O1B
O
SER C:55 C:3075 106.0 0.922 S -73.0 -81.6 47.0 0.409 0.513 A:Q9UK77:0.513
 HOH
 2.498
 O
 O
SER D:55 D:4075 91.0 0.791 S -100.9 157.3 NA NA NA
SER E:55 E:5075 109.0 0.948 S -82.2 -45.1 NA NA NA
SER F:55 F:6075 112.0 0.974 S -72.7 -58.7 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 SER A:55 A:1075 107.0 0.93 S -74.5 -38.9 45.0 0.391 0.539 B:Q9UK77:0.539
 HOH
 2.700
 OG
 O
SER B:55 B:2075 108.0 0.939 S -80.9 -42.4 44.0 0.383 0.556 C:Q9UK77:0.557
 SIA
HOH
 8.973
2.778
 N
N
 O1B
O
SER C:55 C:3075 107.0 0.93 S -70.0 -71.8 46.0 0.4 0.53 A:Q9UK77:0.53
 SIA
HOH
 8.572
2.863
 N
N
 O1A
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 SER A:55 A:75 113.0 0.983 S -92.1 -20.0 57.0 0.496 0.487 A:P23141:0.487
 SCN
HOH
 3.451
3.387
 N
C
 S
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 SER A:55 A:75 91.0 0.791 S -87.4 161.9 33.0 0.287 0.504 A:P23141-3:0.504
 HOH
 2.978
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 SER A:55 A:75 89.0 0.774 S -89.0 162.1 89.0 0.774 0.0 HOH
 2.590
 OG
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 SER A:54 A:75 92.0 0.8 -90.4 153.5 92.0 0.8 0.0 IOD
IOD
HOH
 2.698
3.333
2.971
 O
N
CA
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 SER A:52 A:1075 103.0 0.896 S -98.9 149.0 48.0 0.417 0.479 B:P23141:0.478
 HOH
 2.978
 O
 O
SER B:52 B:2075 104.0 0.904 S -84.7 153.4 37.0 0.322 0.582 C:P23141:0.583
 HOH
 2.999
 N
 O
SER C:52 C:3075 103.0 0.896 S -85.6 153.3 39.0 0.339 0.557 A:P23141:0.557
 HOH
 3.798
 C
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 SER A:53 A:75 132.0 1.0 S -99.3 -19.8 132.0 1.0 0.0 HOH
 2.581
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 SER A:75 A:75 120.0 1.0 S -80.8 -30.4
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ASN A:76 A:76 175.0 1.0 S -88.9 -15.2