Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862733 . G A CCDS32450.1:NM_001025195.1:c.206cCg>cTg_NP_001020366.1:p.69P>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 PRO A:50 A:1068 30.0 0.207 -68.0 144.4 30.0 0.207 0.0 HOH
 2.589
 O
 O
PRO B:50 B:2068 30.0 0.207 -68.7 151.5 30.0 0.207 0.0 HOH
 2.990
 O
 O
PRO C:50 C:3068 26.0 0.179 -67.0 147.3 26.0 0.179 0.0 HOH
 2.895
 O
 O
PRO D:50 D:4068 30.0 0.207 -67.9 147.5 30.0 0.207 0.0 HOH
 3.156
 O
 O
PRO E:50 E:5068 29.0 0.2 -65.7 144.0 29.0 0.2 0.0 HOH
 2.792
 O
 O
PRO F:50 F:6068 25.0 0.172 -65.7 140.1 25.0 0.172 0.0 HOH
 2.895
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 PRO A:50 A:1068 28.0 0.193 -70.6 147.6 28.0 0.193 0.0 HOH
 2.595
 O
 O
PRO B:50 B:2068 28.0 0.193 -57.0 143.5 28.0 0.193 0.0 HOH
 3.052
 O
 O
PRO C:50 C:3068 17.0 0.117 -57.3 142.6 17.0 0.117 0.0 HOH
 2.667
 O
 O
PRO D:50 D:4068 27.0 0.186 -60.1 137.7 NA NA NA
PRO E:50 E:5068 28.0 0.193 -57.7 148.5 NA NA NA
PRO F:50 F:6068 24.0 0.166 -65.9 153.1 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 PRO A:50 A:1068 29.0 0.2 -72.8 150.4 29.0 0.2 0.0 HOH
 2.970
 CA
 O
PRO B:50 B:2068 30.0 0.207 -70.7 131.6 30.0 0.207 0.0 HOH
 2.795
 O
 O
PRO C:50 C:3068 21.0 0.145 -61.7 150.1 21.0 0.145 0.0 HOH
 3.514
 CA
 O
PRO D:50 D:4068 29.0 0.2 -68.7 133.8 29.0 0.2 0.0 HOH
 3.310
 CA
 O
PRO E:50 E:5068 27.0 0.186 -69.7 146.8 27.0 0.186 0.0 HOH
 6.026
 CG
 O
PRO F:50 F:6068 31.0 0.214 -68.7 147.8 31.0 0.214 0.0 HOH
 3.514
 CA
 O
PRO G:50 G:1068 29.0 0.2 -71.7 153.7 NA NA NA
PRO H:50 H:2068 26.0 0.179 -63.0 153.5 NA NA NA
PRO I:50 I:3068 26.0 0.179 -64.3 138.6 NA NA NA
PRO J:50 J:4068 25.0 0.172 -76.4 131.1 NA NA NA
PRO K:50 K:5068 29.0 0.2 -71.2 142.1 NA NA NA
PRO L:50 L:6068 27.0 0.186 -61.4 158.6 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:50 A:1068 28.0 0.193 -73.0 138.5 28.0 0.193 0.0 HOH
 8.124
 N
 O
PRO B:50 B:2068 29.0 0.2 -72.4 140.0 29.0 0.2 0.0 HOH
 3.168
 CA
 O
PRO C:50 C:3068 29.0 0.2 -73.4 139.1 29.0 0.2 0.0 HOH
 3.005
 CA
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:50 A:1068 29.0 0.2 -67.9 135.3 29.0 0.2 0.0 HOH
 2.747
 O
 O
PRO B:50 B:2068 29.0 0.2 -67.4 136.7 29.0 0.2 0.0 HOH
 3.468
 O
 O
PRO C:50 C:3068 25.0 0.172 -68.2 141.2 25.0 0.172 0.0 HOH
 2.721
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:50 A:1068 27.0 0.186 -64.3 142.6 27.0 0.186 0.0 HOH
 3.558
 C
 O
PRO B:50 B:2068 28.0 0.193 -65.9 144.7 28.0 0.193 0.0
PRO C:50 C:3068 26.0 0.179 -64.5 144.3 26.0 0.179 0.0 HOH
 3.827
 CA
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 PRO A:50 A:1068 29.0 0.2 -69.6 141.9 29.0 0.2 0.0 HOH
 2.752
 O
 O
PRO B:50 B:2068 30.0 0.207 -68.8 143.9 30.0 0.207 0.0 HOH
 2.735
 O
 O
PRO C:50 C:3068 20.0 0.138 -66.7 135.2 20.0 0.138 0.0 HOH
 2.594
 O
 O
PRO D:50 D:4068 30.0 0.207 -72.0 143.9 30.0 0.207 0.0 HOH
 2.952
 O
 O
PRO E:50 E:5068 29.0 0.2 -66.7 145.1 29.0 0.2 0.0 HOH
 3.025
 O
 O
PRO F:50 F:6068 28.0 0.193 -68.5 141.1 28.0 0.193 0.0 HOH
 2.825
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:48 A:68 29.0 0.2 -66.0 142.2 29.0 0.2 0.0 HOH
 3.033
 O
 O
PRO B:48 B:68 28.0 0.193 -75.4 142.1 28.0 0.193 0.0 HOH
 6.276
 O
 O
PRO C:48 C:68 26.0 0.179 -74.3 144.3 26.0 0.179 0.0 HOH
 3.250
 CA
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:48 A:68 29.0 0.2 -70.2 138.1 29.0 0.2 0.0 HOH
 2.948
 O
 O
PRO B:48 B:68 30.0 0.207 -63.8 137.1 30.0 0.207 0.0 HOH
 8.046
 N
 O
PRO C:48 C:68 25.0 0.172 -69.3 148.0 25.0 0.172 0.0 HOH
 3.208
 CA
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:48 A:68 26.0 0.179 -67.7 136.8 26.0 0.179 0.0 HOH
 2.757
 O
 O
PRO B:48 B:68 28.0 0.193 -66.3 145.1 28.0 0.193 0.0 HOH
 3.257
 CA
 O
PRO C:48 C:68 27.0 0.186 -68.3 139.7 27.0 0.186 0.0 HOH
 4.097
 CG
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 PRO A:48 A:68 32.0 0.221 -68.1 124.3 32.0 0.221 0.0 HOH
 9.010
 CB
 O
PRO B:48 B:68 25.0 0.172 -68.2 133.8 25.0 0.172 0.0 HOH
 8.221
 N
 O
PRO C:48 C:68 25.0 0.172 -62.8 122.2 25.0 0.172 0.0 HOH
 4.696
 C
 O
PRO D:48 D:68 30.0 0.207 -69.2 126.5 NA NA NA
PRO E:48 E:68 26.0 0.179 -67.5 144.3 NA NA NA
PRO F:48 F:68 29.0 0.2 -67.5 130.2 NA NA NA
PRO G:48 G:68 28.0 0.193 -62.5 146.9 NA NA NA
PRO H:48 H:68 32.0 0.221 -67.3 129.9 NA NA NA
PRO I:48 I:68 31.0 0.214 -60.9 142.1 NA NA NA
PRO J:48 J:68 28.0 0.193 -57.8 138.6 NA NA NA
PRO K:48 K:68 28.0 0.193 -63.5 128.1 NA NA NA
PRO L:48 L:68 26.0 0.179 -75.3 140.9 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 PRO A:48 A:1068 27.0 0.186 -77.0 135.1 27.0 0.186 0.0 HOH
 2.670
 O
 O
PRO B:48 B:2068 31.0 0.214 -69.0 147.4 31.0 0.214 0.0 HOH
 2.934
 O
 O
PRO C:48 C:3068 29.0 0.2 -63.9 146.4 29.0 0.2 0.0 HOH
 3.143
 CA
 O
PRO D:48 D:4068 28.0 0.193 -73.7 142.3 NA NA NA
PRO E:48 E:5068 30.0 0.207 -66.5 143.2 NA NA NA
PRO F:48 F:6068 28.0 0.193 -65.8 141.8 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 PRO A:48 A:1068 27.0 0.186 -63.8 137.8 27.0 0.186 0.0 HOH
 3.517
 CA
 O
PRO B:48 B:2068 30.0 0.207 -71.2 139.7 30.0 0.207 0.0 HOH
 3.439
 CA
 O
PRO C:48 C:3068 30.0 0.207 -61.9 141.1 30.0 0.207 0.0 HOH
 3.259
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 PRO A:48 A:68 24.0 0.166 -61.8 147.5 24.0 0.166 0.0 HOH
 3.130
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 PRO A:48 A:68 26.0 0.179 -65.5 134.7 26.0 0.179 0.0 HOH
 2.923
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 PRO A:48 A:68 28.0 0.193 -63.0 139.0 28.0 0.193 0.0 HOH
 2.644
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 PRO A:47 A:68 20.0 0.138 -63.5 145.2 20.0 0.138 0.0 IOD
HOH
 6.953
3.419
 CD
CA
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 PRO A:45 A:1068 27.0 0.186 -71.5 145.8 27.0 0.186 0.0 HOH
 2.997
 CA
 O
PRO B:45 B:2068 27.0 0.186 -71.0 145.2 27.0 0.186 0.0 HOH
 7.749
 C
 O
PRO C:45 C:3068 26.0 0.179 -71.8 145.7 26.0 0.179 0.0 HOH
 3.161
 CA
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 PRO A:46 A:68 26.0 0.179 -65.6 131.9 26.0 0.179 0.0 HOH
 2.855
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 PRO A:68 A:68 27.0 0.186 -60.4 140.0
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 PRO A:69 A:69 26.0 0.179 -60.6 133.9