Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 55862793 | . | G | A | CCDS32450.1:NM_001025195.1:c.146gCc>gTc_NP_001020366.1:p.49A>V | Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1mx1 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-22 | ALA | A:30 | A:1048 | 0.0 | 0.0 | E | -88.7 | 116.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.214 |
N |
O |
||
| ALA | B:30 | B:2048 | 0.0 | 0.0 | E | -87.4 | 128.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.672 |
CB |
O |
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| ALA | C:30 | C:3048 | 1.0 | 0.009 | E | -87.4 | 126.9 | 1.0 | 0.009 | 0.0 |
HOH |
4.001 |
N |
O |
|||||||||
| ALA | D:30 | D:4048 | 0.0 | 0.0 | E | -88.1 | 124.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.694 |
CA |
O |
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| ALA | E:30 | E:5048 | 1.0 | 0.009 | E | -89.2 | 129.8 | 1.0 | 0.009 | 0.0 |
HOH |
4.335 |
N |
O |
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| ALA | F:30 | F:6048 | 0.0 | 0.0 | E | -90.8 | 122.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.627 |
N |
O |
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| 1mx5 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ALA | A:30 | A:1048 | 0.0 | 0.0 | E | -85.4 | 118.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.262 |
N |
O |
||
| ALA | B:30 | B:2048 | 0.0 | 0.0 | E | -85.0 | 116.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.842 |
CB |
O |
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| ALA | C:30 | C:3048 | 0.0 | 0.0 | E | -82.0 | 124.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.322 |
N |
O |
|||||||||
| ALA | D:30 | D:4048 | 0.0 | 0.0 | E | -83.9 | 115.8 | NA | NA | NA | |||||||||||||
| ALA | E:30 | E:5048 | 1.0 | 0.009 | E | -89.2 | 132.6 | NA | NA | NA | |||||||||||||
| ALA | F:30 | F:6048 | 0.0 | 0.0 | E | -92.0 | 104.8 | NA | NA | NA | |||||||||||||
| 1mx9 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ALA | A:30 | A:1048 | 1.0 | 0.009 | E | -85.6 | 122.2 | 1.0 | 0.009 | 0.0 |
HOH |
6.937 |
CB |
O |
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| ALA | B:30 | B:2048 | 0.0 | 0.0 | E | -93.4 | 114.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.728 |
N |
O |
|||||||||
| ALA | C:30 | C:3048 | 1.0 | 0.009 | E | -85.1 | 130.5 | 1.0 | 0.009 | 0.0 |
HOH |
7.661 |
N |
O |
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| ALA | D:30 | D:4048 | 0.0 | 0.0 | E | -92.8 | 113.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.241 |
CB |
O |
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| ALA | E:30 | E:5048 | 0.0 | 0.0 | E | -96.3 | 112.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.165 |
N |
O |
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| ALA | F:30 | F:6048 | 0.0 | 0.0 | E | -101.7 | 112.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.186 |
N |
O |
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| ALA | G:30 | G:1048 | 1.0 | 0.009 | E | -84.6 | 125.2 | NA | NA | NA | |||||||||||||
| ALA | H:30 | H:2048 | 0.0 | 0.0 | E | -85.2 | 119.1 | NA | NA | NA | |||||||||||||
| ALA | I:30 | I:3048 | 1.0 | 0.009 | E | -87.4 | 123.9 | NA | NA | NA | |||||||||||||
| ALA | J:30 | J:4048 | 1.0 | 0.009 | E | -82.2 | 136.8 | NA | NA | NA | |||||||||||||
| ALA | K:30 | K:5048 | 1.0 | 0.009 | E | -79.4 | 127.0 | NA | NA | NA | |||||||||||||
| ALA | L:30 | L:6048 | 1.0 | 0.009 | E | -82.3 | 105.8 | NA | NA | NA | |||||||||||||
| 2dqy | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:30 | A:1048 | 1.0 | 0.009 | E | -89.7 | 119.9 | 1.0 | 0.009 | 0.0 |
HOH |
4.646 |
CB |
O |
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| ALA | B:30 | B:2048 | 1.0 | 0.009 | E | -89.3 | 119.7 | 1.0 | 0.009 | 0.0 |
HOH |
4.213 |
N |
O |
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| ALA | C:30 | C:3048 | 1.0 | 0.009 | E | -89.4 | 119.7 | 1.0 | 0.009 | 0.0 |
HOH |
4.734 |
CB |
O |
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| 2dqz | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:30 | A:1048 | 0.0 | 0.0 | E | -91.0 | 118.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.683 |
CB |
O |
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| ALA | B:30 | B:2048 | 1.0 | 0.009 | E | -85.0 | 125.9 | 1.0 | 0.009 | 0.0 |
HOH |
6.366 |
N |
O |
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| ALA | C:30 | C:3048 | 1.0 | 0.009 | E | -82.5 | 122.9 | 1.0 | 0.009 | 0.0 |
HOH |
4.304 |
CB |
O |
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| 2dr0 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:30 | A:1048 | 0.0 | 0.0 | E | -88.6 | 125.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.751 |
N |
O |
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| ALA | B:30 | B:2048 | 0.0 | 0.0 | E | -88.9 | 125.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.418 |
N |
O |
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| ALA | C:30 | C:3048 | 0.0 | 0.0 | E | -88.6 | 126.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.984 |
CB |
O |
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| 2h7c | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:30 | A:1048 | 1.0 | 0.009 | E | -92.0 | 125.1 | 1.0 | 0.009 | 0.0 |
HOH |
3.378 |
N |
O |
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| ALA | B:30 | B:2048 | 0.0 | 0.0 | E | -87.5 | 123.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.577 |
N |
O |
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| ALA | C:30 | C:3048 | 1.0 | 0.009 | E | -84.4 | 122.2 | 1.0 | 0.009 | 0.0 |
HOH |
3.651 |
N |
O |
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| ALA | D:30 | D:4048 | 0.0 | 0.0 | E | -88.2 | 121.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.608 |
N |
O |
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| ALA | E:30 | E:5048 | 0.0 | 0.0 | E | -86.8 | 121.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.996 |
N |
O |
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| ALA | F:30 | F:6048 | 0.0 | 0.0 | E | -84.0 | 123.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.517 |
N |
O |
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| 1ya4 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:28 | A:48 | 0.0 | 0.0 | E | -81.8 | 125.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.434 |
C |
O |
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| ALA | B:28 | B:48 | 0.0 | 0.0 | E | -83.5 | 122.5 | 0.0 | 0.0 | 0.0 |
HOH |
8.719 |
O |
O |
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| ALA | C:28 | C:48 | 0.0 | 0.0 | E | -82.0 | 127.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.583 |
CB |
O |
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| 1ya8 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:28 | A:48 | 0.0 | 0.0 | E | -92.2 | 115.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.007 |
CB |
O |
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| ALA | B:28 | B:48 | 0.0 | 0.0 | E | -86.6 | 124.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.772 |
CB |
O |
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| ALA | C:28 | C:48 | 1.0 | 0.009 | E | -86.1 | 132.4 | 1.0 | 0.009 | 0.0 |
HOH |
5.249 |
CB |
O |
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| 1yah | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:28 | A:48 | 0.0 | 0.0 | E | -85.5 | 121.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.697 |
CB |
O |
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| ALA | B:28 | B:48 | 0.0 | 0.0 | E | -85.0 | 120.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.822 |
N |
O |
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| ALA | C:28 | C:48 | 0.0 | 0.0 | E | -87.9 | 120.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.283 |
CB |
O |
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| 1yaj | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:28 | A:48 | 1.0 | 0.009 | E | -93.1 | 127.0 | 1.0 | 0.009 | 0.0 |
HOH |
9.333 |
O |
O |
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| ALA | B:28 | B:48 | 1.0 | 0.009 | E | -84.2 | 118.9 | 1.0 | 0.009 | 0.0 | |||||||||||||
| ALA | C:28 | C:48 | 0.0 | 0.0 | E | -83.5 | 120.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ALA | D:28 | D:48 | 0.0 | 0.0 | E | -87.1 | 110.7 | NA | NA | NA | |||||||||||||
| ALA | E:28 | E:48 | 0.0 | 0.0 | E | -91.3 | 116.9 | NA | NA | NA | |||||||||||||
| ALA | F:28 | F:48 | 0.0 | 0.0 | E | -85.7 | 120.8 | NA | NA | NA | |||||||||||||
| ALA | G:28 | G:48 | 0.0 | 0.0 | E | -81.4 | 124.3 | NA | NA | NA | |||||||||||||
| ALA | H:28 | H:48 | 2.0 | 0.017 | E | -92.9 | 115.9 | NA | NA | NA | |||||||||||||
| ALA | I:28 | I:48 | 1.0 | 0.009 | E | -74.9 | 123.5 | NA | NA | NA | |||||||||||||
| ALA | J:28 | J:48 | 0.0 | 0.0 | E | -87.5 | 121.7 | NA | NA | NA | |||||||||||||
| ALA | K:28 | K:48 | 1.0 | 0.009 | E | -99.8 | 122.1 | NA | NA | NA | |||||||||||||
| ALA | L:28 | L:48 | 0.0 | 0.0 | E | -82.7 | 125.6 | NA | NA | NA | |||||||||||||
| 2hrq | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ALA | A:28 | A:1048 | 0.0 | 0.0 | E | -92.9 | 123.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.517 |
CB |
O |
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| ALA | B:28 | B:2048 | 0.0 | 0.0 | E | -84.2 | 126.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.567 |
N |
O |
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| ALA | C:28 | C:3048 | 1.0 | 0.009 | E | -81.4 | 117.9 | 1.0 | 0.009 | 0.0 |
HOH |
5.132 |
CB |
O |
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| ALA | D:28 | D:4048 | 1.0 | 0.009 | E | -94.7 | 120.5 | NA | NA | NA | |||||||||||||
| ALA | E:28 | E:5048 | 1.0 | 0.009 | E | -83.9 | 127.4 | NA | NA | NA | |||||||||||||
| ALA | F:28 | F:6048 | 1.0 | 0.009 | E | -82.8 | 122.6 | NA | NA | NA | |||||||||||||
| 2hrr | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ALA | A:28 | A:1048 | 0.0 | 0.0 | E | -92.1 | 120.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.783 |
CB |
O |
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| ALA | B:28 | B:2048 | 1.0 | 0.009 | E | -86.4 | 121.0 | 1.0 | 0.009 | 0.0 |
HOH |
3.508 |
N |
O |
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| ALA | C:28 | C:3048 | 0.0 | 0.0 | E | -84.2 | 116.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.727 |
N |
O |
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| 4ab1 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2012-03-07 | ALA | A:28 | A:48 | 1.0 | 0.009 | E | -90.1 | 126.4 | 1.0 | 0.009 | 0.0 |
HOH |
3.465 |
N |
O |
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| 5a7f | 1 | P23141-3 | 99.81 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:28 | A:48 | 1.0 | 0.009 | E | -86.0 | 124.6 | 1.0 | 0.009 | 0.0 |
HOH |
3.835 |
CB |
O |
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| 5a7g | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:28 | A:48 | 1.0 | 0.009 | E | -91.0 | 123.7 | 1.0 | 0.009 | 0.0 |
HOH |
3.716 |
N |
O |
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| 5a7h | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:27 | A:48 | 1.0 | 0.009 | E | -82.4 | 122.5 | 1.0 | 0.009 | 0.0 |
IOD HOH |
3.643 4.682 |
N CB |
I O |
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| 3k9b | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2010-01-19 | ALA | A:25 | A:1048 | 1.0 | 0.009 | E | -99.6 | 120.4 | 1.0 | 0.009 | 0.0 | ||||||
| ALA | B:25 | B:2048 | 1.0 | 0.009 | E | -98.6 | 121.7 | 1.0 | 0.009 | 0.0 | |||||||||||||
| ALA | C:25 | C:3048 | 0.0 | 0.0 | E | -98.9 | 120.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.064 |
CA |
O |
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| 1k4y | 1 | 3219695 | 82.06 | 0.0 |
X-RAY |
2002-05-01 | ALA | A:26 | A:48 | 2.0 | 0.017 | E | -87.5 | 123.6 | 2.0 | 0.017 | 0.0 |
HOH |
5.857 |
CB |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p23141-f1 | 1 | P23141 | 99.82 | 0.0 | ALA | A:48 | A:48 | 0.0 | 0.0 | E | -83.6 | 123.7 | |
| af-q9uky3-f1 | 1 | Q9UKY3 | 93.63 | 3e-170 | ALA | A:49 | A:49 | 0.0 | 0.0 | E | -81.3 | 122.5 | |