Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862805 . G A CCDS32450.1:NM_001025195.1:c.134gCa>gTa_NP_001020366.1:p.45A>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ALA A:26 A:1044 101.0 0.878 S -75.6 -56.0 101.0 0.878 0.0 HOH
 2.692
 N
 O
ALA B:26 B:2044 104.0 0.904 S -63.0 -47.3 104.0 0.904 0.0 HOH
 2.584
 N
 O
ALA C:26 C:3044 106.0 0.922 S -64.3 -58.1 106.0 0.922 0.0 HOH
 2.976
 N
 O
ALA D:26 D:4044 102.0 0.887 E -66.1 -48.6 102.0 0.887 0.0 HOH
 3.068
 N
 O
ALA E:26 E:5044 98.0 0.852 -74.2 -29.5 98.0 0.852 0.0 HOH
 3.481
 N
 O
ALA F:26 F:6044 104.0 0.904 S -76.0 -31.4 104.0 0.904 0.0 HOH
 3.080
 N
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:26 A:1044 98.0 0.852 S -63.5 -62.2 98.0 0.852 0.0 HOH
 3.165
 N
 O
ALA B:26 B:2044 94.0 0.817 S -77.2 -49.8 94.0 0.817 0.0 HOH
 3.515
 N
 O
ALA C:26 C:3044 104.0 0.904 S -59.4 -49.6 104.0 0.904 0.0 HOH
 2.666
 O
 O
ALA D:26 D:4044 97.0 0.843 S -71.2 -47.7 NA NA NA
ALA E:26 E:5044 104.0 0.904 S -67.2 -43.5 NA NA NA
ALA F:26 F:6044 101.0 0.878 E -67.3 -56.2 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ALA A:26 A:1044 107.0 0.93 S -64.4 -42.7 107.0 0.93 0.0 HOH
 2.714
 N
 O
ALA B:26 B:2044 99.0 0.861 S -56.9 -75.6 99.0 0.861 0.0 HOH
 2.786
 N
 O
ALA C:26 C:3044 100.0 0.87 S -72.4 -37.0 100.0 0.87 0.0 HOH
 3.034
 O
 O
ALA D:26 D:4044 111.0 0.965 S -59.5 -53.0 111.0 0.965 0.0 HOH
 6.753
 N
 O
ALA E:26 E:5044 93.0 0.809 E -60.2 -82.2 93.0 0.809 0.0 HOH
 7.093
 N
 O
ALA F:26 F:6044 105.0 0.913 S -60.9 -48.1 105.0 0.913 0.0 HOH
 3.153
 N
 O
ALA G:26 G:1044 105.0 0.913 S -78.8 -24.6 NA NA NA
ALA H:26 H:2044 102.0 0.887 S -57.1 -59.6 NA NA NA
ALA I:26 I:3044 96.0 0.835 S -95.3 -33.6 NA NA NA
ALA J:26 J:4044 107.0 0.93 S -57.1 -72.9 NA NA NA
ALA K:26 K:5044 96.0 0.835 S -68.9 -71.9 NA NA NA
ALA L:26 L:6044 105.0 0.913 E -51.4 -50.1 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:26 A:1044 96.0 0.835 S -72.1 -72.8 96.0 0.835 0.0 HOH
 3.197
 O
 O
ALA B:26 B:2044 95.0 0.826 S -72.6 -75.1 95.0 0.826 0.0 HOH
 7.096
 N
 O
ALA C:26 C:3044 93.0 0.809 S -74.0 -75.9 93.0 0.809 0.0 HOH
 2.706
 C
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:26 A:1044 105.0 0.913 S -60.2 -49.1 105.0 0.913 0.0 HOH
 2.892
 N
 O
ALA B:26 B:2044 101.0 0.878 S -61.8 -59.6 101.0 0.878 0.0 HOH
 2.472
 N
 O
ALA C:26 C:3044 97.0 0.843 S -72.8 -42.9 97.0 0.843 0.0 HOH
 3.447
 N
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:26 A:1044 103.0 0.896 S -57.4 -70.7 103.0 0.896 0.0 HOH
 3.754
 O
 O
ALA B:26 B:2044 101.0 0.878 S -58.2 -71.6 101.0 0.878 0.0 HOH
 2.768
 N
 O
ALA C:26 C:3044 102.0 0.887 S -58.4 -71.4 102.0 0.887 0.0 HOH
 4.380
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ALA A:26 A:1044 108.0 0.939 S -70.9 -47.0 108.0 0.939 0.0 HOH
 2.908
 N
 O
ALA B:26 B:2044 104.0 0.904 S -63.6 -48.3 104.0 0.904 0.0 HOH
 3.043
 N
 O
ALA C:26 C:3044 103.0 0.896 S -75.8 -40.4 103.0 0.896 0.0 HOH
 2.849
 N
 O
ALA D:26 D:4044 100.0 0.87 S -70.5 -63.0 100.0 0.87 0.0 HOH
 2.610
 O
 O
ALA E:26 E:5044 102.0 0.887 -69.0 -25.1 102.0 0.887 0.0 HOH
 2.458
 O
 O
ALA F:26 F:6044 100.0 0.87 S -68.9 -50.0 100.0 0.87 0.0 HOH
 4.563
 C
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:24 A:44 106.0 0.922 S -56.1 -60.8 106.0 0.922 0.0 HOH
 4.629
 N
 O
ALA B:24 B:44 100.0 0.87 S -61.3 -72.5 100.0 0.87 0.0
ALA C:24 C:44 101.0 0.878 S -58.3 -69.2 101.0 0.878 0.0 HOH
 4.946
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:24 A:44 102.0 0.887 E -52.6 -67.6 102.0 0.887 0.0 HOH
 6.097
 C
 O
ALA B:24 B:44 107.0 0.93 S -58.3 -59.1 107.0 0.93 0.0 HOH
 4.030
 O
 O
ALA C:24 C:44 102.0 0.887 S -75.6 -35.3 102.0 0.887 0.0 HOH
 2.872
 N
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:24 A:44 99.0 0.861 S -65.2 -58.9 99.0 0.861 0.0 HOH
 2.609
 N
 O
ALA B:24 B:44 97.0 0.843 S -63.1 -69.1 97.0 0.843 0.0 HOH
 3.727
 O
 O
ALA C:24 C:44 99.0 0.861 S -66.4 -65.3 99.0 0.861 0.0 HOH
 2.642
 N
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ALA A:24 A:44 105.0 0.913 E -77.1 -45.3 105.0 0.913 0.0
ALA B:24 B:44 93.0 0.809 S -94.1 -80.6 93.0 0.809 0.0
ALA C:24 C:44 102.0 0.887 S -81.3 -31.2 102.0 0.887 0.0
ALA D:24 D:44 100.0 0.87 S -82.4 -62.8 NA NA NA
ALA E:24 E:44 96.0 0.835 S -71.3 -79.3 NA NA NA
ALA F:24 F:44 103.0 0.896 S -70.4 -25.1 NA NA NA
ALA G:24 G:44 101.0 0.878 S -78.7 -21.3 NA NA NA
ALA H:24 H:44 106.0 0.922 S -63.0 -55.2 NA NA NA
ALA I:24 I:44 96.0 0.835 S -70.6 -75.3 NA NA NA
ALA J:24 J:44 98.0 0.852 S -61.6 -43.4 NA NA NA
ALA K:24 K:44 104.0 0.904 S -60.0 -46.7 NA NA NA
ALA L:24 L:44 105.0 0.913 S -66.4 -37.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:24 A:1044 101.0 0.878 S -75.1 -42.4 101.0 0.878 0.0 HOH
 5.689
 C
 O
ALA B:24 B:2044 101.0 0.878 E -70.0 -46.5 101.0 0.878 0.0 HOH
 5.322
 C
 O
ALA C:24 C:3044 97.0 0.843 S -72.7 -46.7 97.0 0.843 0.0 HOH
 6.639
 O
 O
ALA D:24 D:4044 102.0 0.887 S -75.7 -37.2 NA NA NA
ALA E:24 E:5044 103.0 0.896 E -74.2 -32.2 NA NA NA
ALA F:24 F:6044 100.0 0.87 S -73.7 -44.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ALA A:24 A:1044 101.0 0.878 S -70.3 -52.9 101.0 0.878 0.0 HOH
 2.784
 N
 O
ALA B:24 B:2044 104.0 0.904 S -67.4 -44.2 104.0 0.904 0.0 HOH
 7.454
 N
 O
ALA C:24 C:3044 97.0 0.843 S -71.4 -47.9 97.0 0.843 0.0 HOH
 2.488
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ALA A:24 A:44 93.0 0.809 S -87.8 -27.1 93.0 0.809 0.0 HOH
 3.045
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ALA A:24 A:44 96.0 0.835 S -72.5 -38.0 96.0 0.835 0.0 HOH
 3.096
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:24 A:44 106.0 0.922 S -70.3 -37.1 106.0 0.922 0.0 HOH
 3.108
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ALA A:23 A:44 103.0 0.896 S -74.0 -47.4 103.0 0.896 0.0 IOD
HOH
 8.223
2.462
 O
N
 I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ALA A:21 A:1044 108.0 0.939 S -77.0 -44.7 108.0 0.939 0.0
ALA B:21 B:2044 108.0 0.939 S -74.6 -46.5 108.0 0.939 0.0
ALA C:21 NA:NA DO NA DO DO DO NA NA NA
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ALA A:22 A:44 110.0 0.957 S -66.0 -43.0 110.0 0.957 0.0 HOH
 3.477
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ALA A:44 A:44 77.0 0.67 S -75.4 -36.1
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 ALA A:45 A:45 108.0 0.939 S -73.6 -37.5