Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862840 . T A CCDS32450.1:NM_001025195.1:c.99aaA>aaT_NP_001020366.1:p.33K>N Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 LYS A:14 A:1032 82.0 0.41 E -86.4 145.4 82.0 0.41 0.0 NAG
SIA
HOH
 9.952
9.059
3.031
 O
O
N
 C8
O2
O
LYS B:14 B:2032 84.0 0.42 E -76.2 142.2 84.0 0.42 0.0 SIA
HOH
 8.004
3.125
 O
N
 C9
O
LYS C:14 C:3032 82.0 0.41 E -83.8 140.6 82.0 0.41 0.0 HOH
 2.875
 N
 O
LYS D:14 D:4032 85.0 0.425 E -78.2 145.4 85.0 0.425 0.0 SIA
HOH
 7.607
3.112
 O
N
 O1A
O
LYS E:14 E:5032 84.0 0.42 E -78.3 145.4 84.0 0.42 0.0 SIA
HOH
 7.937
3.005
 O
N
 C11
O
LYS F:14 F:6032 88.0 0.44 E -82.2 150.0 88.0 0.44 0.0 HOH
 2.986
 N
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LYS A:14 A:1032 89.0 0.445 E -74.6 141.8 89.0 0.445 0.0 SIA
HOH
 9.180
2.881
 O
N
 N5
O
LYS B:14 B:2032 85.0 0.425 E -78.5 142.0 85.0 0.425 0.0 SIA
HOH
 9.155
2.869
 O
CG
 C11
O
LYS C:14 C:3032 86.0 0.43 E -89.4 136.5 86.0 0.43 0.0 HOH
 2.789
 N
 O
LYS D:14 D:4032 88.0 0.44 E -71.7 135.2 NA NA NA
LYS E:14 E:5032 87.0 0.435 E -84.7 144.6 NA NA NA
LYS F:14 F:6032 85.0 0.425 E -78.2 141.8 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LYS A:14 A:1032 90.0 0.45 E -72.6 146.7 90.0 0.45 0.0 HOH
 2.727
 NZ
 O
LYS B:14 B:2032 81.0 0.405 E -85.9 150.9 81.0 0.405 0.0 HOH
 2.910
 NZ
 O
LYS C:14 C:3032 90.0 0.45 E -95.7 145.1 90.0 0.45 0.0 NAG
HOH
 8.399
5.577
 O
N
 C8
O
LYS D:14 D:4032 82.0 0.41 E -88.4 132.8 82.0 0.41 0.0 NAG
HOH
 7.596
3.143
 O
N
 C8
O
LYS E:14 E:5032 98.0 0.49 E -59.9 134.6 98.0 0.49 0.0 HOH
 7.711
 O
 O
LYS F:14 F:6032 90.0 0.45 E -83.5 129.9 90.0 0.45 0.0 NAG
HOH
 8.062
2.890
 O
N
 C8
O
LYS G:14 G:1032 87.0 0.435 E -86.9 131.2 NA NA NA
LYS H:14 H:2032 75.0 0.375 E -89.2 131.3 NA NA NA
LYS I:14 I:3032 90.0 0.45 E -87.1 131.0 NA NA NA
LYS J:14 J:4032 77.0 0.385 E -72.3 139.5 NA NA NA
LYS K:14 K:5032 95.0 0.475 E -68.5 140.4 NA NA NA
LYS L:14 L:6032 93.0 0.465 E -109.2 123.8 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:14 A:1032 92.0 0.46 E -58.6 141.3 92.0 0.46 0.0 NAG
SIA
HOH
 9.987
7.296
2.853
 O
O
N
 C1
O1B
O
LYS B:14 B:2032 92.0 0.46 E -60.1 142.2 92.0 0.46 0.0 NAG
SIA
HOH
 9.891
7.610
2.844
 O
O
N
 C1
O1B
O
LYS C:14 C:3032 91.0 0.455 E -58.7 141.5 91.0 0.455 0.0 NAG
SIA
HOH
 9.707
8.334
2.856
 O
O
NZ
 C1
O1B
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:14 A:1032 91.0 0.455 E -76.6 142.5 91.0 0.455 0.0 NAG
SIA
HOH
 9.473
8.521
2.967
 O
O
N
 C1
O1B
O
LYS B:14 B:2032 88.0 0.44 E -74.6 144.1 88.0 0.44 0.0 NAG
SIA
HOH
 9.930
7.031
2.823
 O
O
N
 C1
O1B
O
LYS C:14 C:3032 94.0 0.47 E -78.5 138.9 94.0 0.47 0.0 SIA
HOH
 7.344
2.839
 O
NZ
 O1B
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:14 A:1032 89.0 0.445 E -75.9 142.5 89.0 0.445 0.0 NAG
SIA
HOH
 9.891
8.856
3.733
 O
O
N
 C1
O1B
O
LYS B:14 B:2032 90.0 0.45 E -76.0 141.6 90.0 0.45 0.0 NAG
SIA
HOH
 9.682
7.006
2.743
 O
O
NZ
 C1
O1B
O
LYS C:14 C:3032 90.0 0.45 E -76.9 142.4 90.0 0.45 0.0 SIA
HOH
 7.621
2.793
 O
N
 O1A
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LYS A:14 A:1032 91.0 0.455 E -82.4 144.8 91.0 0.455 0.0 HOH
 3.028
 N
 O
LYS B:14 B:2032 79.0 0.395 E -79.2 145.3 79.0 0.395 0.0 HOH
 3.135
 N
 O
LYS C:14 C:3032 84.0 0.42 E -81.2 145.2 84.0 0.42 0.0 HOH
 3.106
 N
 O
LYS D:14 D:4032 94.0 0.47 E -83.2 142.6 94.0 0.47 0.0 SIA
HOH
 8.000
2.980
 O
N
 O10
O
LYS E:14 E:5032 83.0 0.415 E -78.9 146.0 83.0 0.415 0.0 NAG
SIA
HOH
 9.804
8.249
2.952
 O
O
N
 C8
O1A
O
LYS F:14 F:6032 81.0 0.405 E -81.8 145.5 81.0 0.405 0.0 NAG
HOH
 9.467
3.038
 O
CB
 C8
O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:12 A:32 94.0 0.47 E -80.3 141.5 94.0 0.47 0.0 NAG
SIA
HOH
 9.748
8.680
2.856
 O
O
N
 O6
O1B
O
LYS B:12 B:32 93.0 0.465 E -72.3 144.8 93.0 0.465 0.0 SIA
HOH
 7.379
6.961
 O
O
 O1B
O
LYS C:12 C:32 90.0 0.45 E -75.2 140.9 90.0 0.45 0.0 NAG
SIA
HOH
 9.927
7.623
2.488
 O
O
N
 C1
O1B
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:12 A:32 89.0 0.445 E -78.6 140.9 89.0 0.445 0.0 NAG
SIA
HOH
 9.700
7.689
3.467
 O
O
N
 C1
O1B
O
LYS B:12 B:32 87.0 0.435 E -85.2 149.9 87.0 0.435 0.0 NAG
SIA
HOH
 9.881
7.329
9.215
 O
O
O
 C1
O1B
O
LYS C:12 C:32 86.0 0.43 E -92.0 140.9 86.0 0.43 0.0 NAG
SIA
HOH
 9.586
8.301
3.258
 O
O
N
 C1
O1B
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:12 A:32 89.0 0.445 E -78.0 147.4 89.0 0.445 0.0 NAG
SIA
HOH
 9.907
8.480
6.672
 O
O
O
 O6
O1B
O
LYS B:12 B:32 87.0 0.435 E -78.4 142.7 87.0 0.435 0.0 NAG
SIA
HOH
 9.874
8.014
3.450
 O
O
N
 O7
O1B
O
LYS C:12 C:32 88.0 0.44 E -81.8 142.2 88.0 0.44 0.0 SIA
NAG
HOH
 8.737
9.987
3.094
 O
O
N
 O9
C1
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LYS A:12 A:32 98.0 0.49 E -81.0 149.6 98.0 0.49 0.0 NAG
SIA
HOH
 9.984
8.554
2.709
 O
O
NZ
 C1
C9
O
LYS B:12 B:32 100.0 0.5 E -84.0 121.6 100.0 0.5 0.0 NAG
SIA
 9.795
7.753
 O
O
 C8
O1B
LYS C:12 C:32 94.0 0.47 E -74.6 143.4 94.0 0.47 0.0 SIA
HOH
 8.708
3.591
 O
NZ
 O1B
O
LYS D:12 D:32 95.0 0.475 E -72.2 151.9 NA NA NA
LYS E:12 E:32 86.0 0.43 E -74.7 125.5 NA NA NA
LYS F:12 F:32 94.0 0.47 E -75.1 142.5 NA NA NA
LYS G:12 G:32 92.0 0.46 E -79.6 132.4 NA NA NA
LYS H:12 H:32 98.0 0.49 E -58.6 141.6 NA NA NA
LYS I:12 I:32 84.0 0.42 E -76.9 132.5 NA NA NA
LYS J:12 J:32 98.0 0.49 E -91.6 135.7 NA NA NA
LYS K:12 K:32 98.0 0.49 E -77.9 131.4 NA NA NA
LYS L:12 L:32 91.0 0.455 E -90.4 133.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LYS A:12 A:1032 95.0 0.475 E -80.7 144.1 95.0 0.475 0.0 NAG
SIA
HOH
 9.732
7.591
2.775
 O
O
NZ
 C6
C11
O
LYS B:12 B:2032 80.0 0.4 E -80.2 142.5 80.0 0.4 0.0 NAG
SIA
HOH
 8.954
7.783
3.133
 O
O
N
 C1
O1B
O
LYS C:12 C:3032 87.0 0.435 E -82.8 149.5 87.0 0.435 0.0 SIA
HOH
 8.351
3.123
 O
N
 O1B
O
LYS D:12 D:4032 89.0 0.445 E -87.7 147.1 NA NA NA
LYS E:12 E:5032 87.0 0.435 E -84.2 143.8 NA NA NA
LYS F:12 F:6032 98.0 0.49 E -73.4 151.0 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LYS A:12 A:1032 93.0 0.465 E -77.2 149.8 93.0 0.465 0.0 NAG
SIA
HOH
 9.394
8.771
3.049
 O
O
N
 O6
O8
O
LYS B:12 B:2032 80.0 0.4 E -84.6 141.1 80.0 0.4 0.0 NAG
SIA
HOH
 9.186
7.508
3.141
 O
O
N
 C1
O1B
O
LYS C:12 C:3032 103.0 0.515 E -80.0 140.6 103.0 0.515 0.0 NAG
SIA
HOH
 9.541
7.358
2.629
 O
O
NZ
 C8
O1A
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 LYS A:12 A:32 92.0 0.46 E -77.5 148.1 92.0 0.46 0.0 SCN
HOH
 7.667
3.163
 O
N
 N
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 LYS A:12 A:32 91.0 0.455 E -79.0 146.2 91.0 0.455 0.0 HOH
 3.151
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LYS A:12 A:32 84.0 0.42 E -82.0 143.4 84.0 0.42 0.0 HOH
 3.017
 N
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LYS A:11 A:32 86.0 0.43 E -81.6 144.7 86.0 0.43 0.0 IOD
IOD
HOH
 6.259
9.063
2.878
 O
O
N
 I
I
O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 LYS A:9 A:1032 87.0 0.435 E -89.7 141.7 87.0 0.435 0.0 HOH
 6.222
 O
 O
LYS B:9 B:2032 89.0 0.445 E -90.8 141.4 89.0 0.445 0.0 HOH
 7.534
 N
 O
LYS C:9 C:3032 90.0 0.45 E -90.7 142.1 90.0 0.45 0.0 HOH
 2.984
 N
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 LYS A:10 A:32 95.0 0.475 -81.8 146.7 95.0 0.475 0.0 NAG
HOH
 9.936
2.721
 O
NZ
 C8
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 LYS A:32 A:32 85.0 0.425 E -80.1 141.2
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 LYS A:33 A:33 79.0 0.395 E -78.3 140.3