Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55862871 . G A CCDS32450.1:NM_001025195.1:c.68tCg>tTg_NP_001020366.1:p.23S>L Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 SER A:4 A:1022 90.0 0.783 -40.8 111.5 90.0 0.783 0.0 NAG
HOH
 9.836
2.785
 C
N
 C8
O
SER B:4 B:2022 150.0 1.0 360.0 148.8 150.0 1.0 0.0 NAG
HOH
 8.403
2.624
 C
N
 O6
O
SER C:4 C:3022 141.0 1.0 360.0 166.5 141.0 1.0 0.0 HOH
 2.528
 N
 O
SER D:4 D:4022 155.0 1.0 360.0 134.4 155.0 1.0 0.0 HOH
 2.608
 O
 O
SER E:4 E:5022 147.0 1.0 360.0 142.0 147.0 1.0 0.0 NAG
HOH
 8.296
2.612
 C
N
 O7
O
SER F:4 F:6022 144.0 1.0 360.0 161.1 144.0 1.0 0.0 HOH
 2.680
 N
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 SER A:4 A:1022 108.0 0.939 -52.9 106.3 108.0 0.939 0.0 NAG
HOH
 9.424
2.877
 C
N
 C8
O
SER B:4 B:2022 138.0 1.0 360.0 129.5 138.0 1.0 0.0 HOH
 2.930
 CB
 O
SER C:4 C:3022 147.0 1.0 360.0 114.5 147.0 1.0 0.0 HOH
 3.350
 OG
 O
SER D:4 D:4022 102.0 0.887 -81.2 120.1 NA NA NA
SER E:4 E:5022 144.0 1.0 360.0 141.7 NA NA NA
SER F:4 F:6022 144.0 1.0 360.0 140.6 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 SER A:4 A:1022 89.0 0.774 -111.3 154.2 89.0 0.774 0.0 HOH
 3.766
 N
 O
SER B:4 B:2022 82.0 0.713 -171.0 136.1 82.0 0.713 0.0 HOH
 8.564
 O
 O
SER C:4 C:3022 148.0 1.0 360.0 149.1 148.0 1.0 0.0 HOH
 2.512
 N
 O
SER D:4 D:4022 98.0 0.852 -38.9 118.7 98.0 0.852 0.0 HOH
 2.833
 N
 O
SER E:4 E:5022 149.0 1.0 360.0 127.0 149.0 1.0 0.0 HOH
 2.700
 N
 O
SER F:4 F:6022 148.0 1.0 360.0 163.2 148.0 1.0 0.0 HOH
 2.616
 N
 O
SER G:4 G:1022 97.0 0.843 -38.7 105.0 NA NA NA
SER H:4 H:2022 155.0 1.0 360.0 52.0 NA NA NA
SER I:4 I:3022 145.0 1.0 360.0 140.3 NA NA NA
SER J:4 J:4022 99.0 0.861 -99.4 123.6 NA NA NA
SER K:4 K:5022 147.0 1.0 360.0 139.9 NA NA NA
SER L:4 L:6022 149.0 1.0 360.0 125.4 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:4 A:1022 80.0 0.696 -174.9 133.8 80.0 0.696 0.0 NAG
HOH
 8.260
6.551
 C
C
 O6
O
SER B:4 B:2022 84.0 0.73 -127.1 132.5 84.0 0.73 0.0 NAG
HOH
 7.696
3.339
 C
N
 C6
O
SER C:4 C:3022 97.0 0.843 -65.4 136.9 97.0 0.843 0.0 NAG
HOH
 8.665
5.638
 OG
N
 O7
O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:4 A:1022 79.0 0.687 -167.2 140.6 79.0 0.687 0.0 NAG
HOH
 9.656
2.717
 C
O
 O6
O
SER B:4 B:2022 95.0 0.826 -61.9 139.5 95.0 0.826 0.0 NAG
 7.047
 OG
 C6
SER C:4 C:3022 93.0 0.809 -93.6 152.5 93.0 0.809 0.0 HOH
 2.834
 N
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:4 A:1022 91.0 0.791 -152.8 132.5 91.0 0.791 0.0 HOH
 5.670
 N
 O
SER B:4 B:2022 105.0 0.913 -85.4 133.3 105.0 0.913 0.0 NAG
HOH
 8.255
7.498
 C
C
 C6
O
SER C:4 C:3022 99.0 0.861 -58.8 135.8 99.0 0.861 0.0 NAG
HOH
 7.577
4.758
 C
O
 O6
O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 SER A:4 A:1022 102.0 0.887 69.1 78.3 102.0 0.887 0.0 HOH
 5.193
 O
 O
SER B:4 B:2022 146.0 1.0 360.0 137.2 146.0 1.0 0.0 HOH
 2.703
 O
 O
SER C:4 C:3022 146.0 1.0 360.0 160.5 146.0 1.0 0.0 NAG
HOH
 9.341
2.882
 C
N
 C8
O
SER D:4 D:4022 91.0 0.791 -81.0 166.9 91.0 0.791 0.0 HOH
 3.010
 CA
 O
SER E:4 E:5022 144.0 1.0 360.0 159.1 144.0 1.0 0.0 NAG
HOH
 9.141
3.486
 C
OG
 O7
O
SER F:4 F:6022 143.0 1.0 360.0 156.1 143.0 1.0 0.0 HOH
 3.053
 N
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:2 A:22 141.0 1.0 360.0 55.2 141.0 1.0 0.0
SER B:2 B:22 103.0 0.896 -70.1 177.0 103.0 0.896 0.0 NAG
HOH
 7.269
3.677
 CB
O
 C6
O
SER C:2 C:22 83.0 0.722 -133.6 125.7 83.0 0.722 0.0 NAG
HOH
 7.083
4.955
 C
O
 O6
O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:2 A:22 82.0 0.713 -135.9 143.8 82.0 0.713 0.0 NAG
HOH
 7.050
4.983
 OG
O
 O6
O
SER B:2 B:22 105.0 0.913 -88.6 123.1 105.0 0.913 0.0 NAG
HOH
 7.877
4.980
 C
C
 C6
O
SER C:2 C:22 84.0 0.73 -96.8 145.1 84.0 0.73 0.0 NAG
HOH
 7.664
6.718
 C
C
 O6
O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:2 A:22 84.0 0.73 -136.2 133.3 84.0 0.73 0.0 NAG
HOH
 9.961
2.983
 C
OG
 O3
O
SER B:2 B:22 99.0 0.861 -80.0 124.7 99.0 0.861 0.0 NAG
HOH
 7.811
3.439
 C
C
 O6
O
SER C:2 C:22 96.0 0.835 -111.5 136.8 96.0 0.835 0.0 NAG
HOH
 8.007
4.904
 C
C
 O6
O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 SER A:2 A:22 87.0 0.757 -176.0 119.9 87.0 0.757 0.0 NAG
 7.023
 C
 O6
SER B:2 B:22 98.0 0.852 -121.2 119.7 98.0 0.852 0.0 NAG
 7.980
 C
 C6
SER C:2 C:22 89.0 0.774 -79.6 137.9 89.0 0.774 0.0 NAG
 7.253
 C
 O6
SER D:2 D:22 87.0 0.757 -97.4 122.9 NA NA NA
SER E:2 E:22 109.0 0.948 -59.7 120.5 NA NA NA
SER F:2 F:22 93.0 0.809 -76.4 118.3 NA NA NA
SER G:2 G:22 93.0 0.809 -89.6 125.1 NA NA NA
SER H:2 H:22 109.0 0.948 -98.1 360.0 NA NA NA
SER I:2 I:22 96.0 0.835 -58.2 111.0 NA NA NA
SER J:2 J:22 92.0 0.8 -55.7 153.3 NA NA NA
SER K:2 K:22 90.0 0.783 -118.5 133.9 NA NA NA
SER L:2 L:22 101.0 0.878 -64.6 128.1 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 SER A:2 A:1022 86.0 0.748 -110.3 125.0 86.0 0.748 0.0 NAG
HOH
 8.462
5.237
 C
C
 O7
O
SER B:2 B:2022 144.0 1.0 360.0 122.5 144.0 1.0 0.0 NAG
HOH
 9.229
2.486
 C
O
 O6
O
SER C:2 C:3022 145.0 1.0 360.0 118.5 145.0 1.0 0.0 NAG
HOH
 9.882
3.208
 C
CB
 O6
O
SER D:2 D:4022 92.0 0.8 -113.8 143.1 NA NA NA
SER E:2 E:5022 143.0 1.0 360.0 122.1 NA NA NA
SER F:2 F:6022 144.0 1.0 360.0 98.7 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 SER A:2 A:1022 88.0 0.765 -108.8 152.0 88.0 0.765 0.0 NAG
HOH
 9.035
2.535
 C
O
 O7
O
SER B:2 B:2022 144.0 1.0 360.0 124.4 144.0 1.0 0.0 NAG
HOH
 8.101
2.359
 C
O
 O6
O
SER C:2 C:3022 142.0 1.0 360.0 133.7 142.0 1.0 0.0 NAG
HOH
 8.095
3.622
 OG
OG
 O7
O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 SER A:2 A:22 152.0 1.0 360.0 154.7 152.0 1.0 0.0 NAG
HOH
 9.442
4.641
 C
C
 C8
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 SER A:2 A:22 98.0 0.852 -71.1 151.0 98.0 0.852 0.0 NAG
HOH
 9.078
5.201
 C
C
 C8
O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 SER A:2 A:22 93.0 0.809 -73.7 130.8 93.0 0.809 0.0 HOH
 3.501
 C
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 SER A:1 A:22 94.0 0.817 360.0 -4.9 94.0 0.817 0.0 IOD
HOH
 9.388
8.897
 CB
C
 I
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 SER A:22 A:22 80.0 0.696 S -133.2 137.6
af-q9uky3-f1 1 Q9UKY3 93.63 3e-170 SER A:23 A:23 103.0 0.896 -51.0 139.2