Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 58750684 . A C CCDS10801.1:NM_002080.2:c.736Tac>Gac_NP_002071.2:p.246Y>D Homo sapiens glutamic-oxaloacetic transaminase 2 (GOT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ax8 1 P00505 99.75 0.0 X-RAY
 2016-03-16 TYR A:217 A:246 13.0 0.057 S -130.7 35.1 13.0 0.057 0.0
TYR B:217 B:246 15.0 0.065 -125.4 28.9 NA NA NA
TYR C:217 C:246 19.0 0.083 -123.7 27.8 19.0 0.083 0.0
TYR D:217 D:246 9.0 0.039 -127.7 26.4 NA NA NA
3hlm 1 P05202 95.26 0.0 X-RAY
 2010-06-02 TYR A:217 A:246 4.0 0.017 -137.1 12.3 4.0 0.017 0.0 GOL
HOH
 5.872
2.645
 OH
N
 O1
O
TYR B:217 B:246 5.0 0.022 -136.0 22.2 5.0 0.022 0.0 HOH
 3.138
 N
 O
TYR C:217 C:246 5.0 0.022 -138.8 35.5 NA NA NA
TYR D:217 D:246 5.0 0.022 -126.5 14.3 NA NA NA
3pd6 1 P05202 95.26 0.0 X-RAY
 2010-11-10 TYR A:217 A:246 14.0 0.061 -140.9 22.9 13.0 0.057 0.004 I:None:0.004
 PMP
KYN
HOH
 2.654
5.223
2.931
 OH
OH
N
 O3
N
O
TYR C:217 C:246 17.0 0.074 -128.2 32.0 NA NA NA
3pd6 2 P05202 95.26 0.0 X-RAY
 2010-11-10 TYR B:217 B:246 4.0 0.017 -125.3 20.8 4.0 0.017 0.0 GOL
HOH
 4.842
2.899
 OH
N
 O3
O
TYR D:217 D:246 5.0 0.022 -130.7 24.2 NA NA NA
3pdb 1 P05202 95.26 0.0 X-RAY
 2010-11-10 TYR A:217 A:246 4.0 0.017 -133.6 24.9 4.0 0.017 0.0 GOL
OAA
HOH
 9.651
5.173
2.844
 O
OH
N
 O1
O3
O
TYR C:217 C:246 4.0 0.017 -137.5 17.9 NA NA NA
3pdb 2 P05202 95.26 0.0 X-RAY
 2010-11-10 TYR B:217 B:246 12.0 0.052 -126.5 20.5 12.0 0.052 0.0 BME
PMP
HOH
 4.651
2.630
2.839
 OH
OH
N
 C1
O3
O
TYR D:217 D:246 16.0 0.07 -128.8 22.8 NA NA NA
1ama 1 P00508 86.28 0.0 X-RAY
 1993-10-31 TYR A:217 A:225 6.0 0.026 -119.8 35.6 6.0 0.026 0.0 PLA
HOH
 2.759
2.733
 OH
N
 O3
O
1ivr 1 P00508 86.28 0.0 X-RAY
 1997-07-23 TYR A:217 A:217 3.0 0.013 -116.0 24.7 3.0 0.013 0.0 CBA
HOH
 2.585
2.753
 OH
N
 O3
O
1map 1 P00508 86.28 0.0 X-RAY
 1994-01-31 TYR A:217 A:225 5.0 0.022 -121.1 31.3 5.0 0.022 0.0 KET
HOH
 2.768
2.911
 OH
N
 O3
O
1maq 1 P00508 86.28 0.0 X-RAY
 1994-01-31 TYR A:217 A:225 5.0 0.022 -124.3 38.1 5.0 0.022 0.0 PGU
HOH
 2.806
2.772
 OH
N
 O3
O
1oxo 1 P00508 86.28 0.0 X-RAY
 1996-06-10 TYR A:217 A:225 16.0 0.07 -138.8 35.0 16.0 0.07 0.0 IK2
HOH
 2.632
2.956
 OH
N
 O3
O
TYR B:217 B:225 21.0 0.091 -125.9 30.3 21.0 0.091 0.0 IK2
HOH
 2.630
3.077
 OH
N
 O3
O
1oxp 1 P00508 86.28 0.0 X-RAY
 1996-06-10 TYR A:217 A:225 14.0 0.061 -114.5 31.1 14.0 0.061 0.0 IK2
HOH
 2.560
2.878
 OH
N
 O3
O
1tar 1 P00508 86.28 0.0 X-RAY
 1994-01-31 TYR A:217 A:225 13.0 0.057 -138.2 29.1 13.0 0.057 0.0 PLP
HOH
 2.439
2.684
 OH
N
 O3
O
TYR B:217 B:225 13.0 0.057 -138.9 22.1 13.0 0.057 0.0 PLP
HOH
 2.612
2.922
 OH
N
 O3
O
1tas 1 P00508 86.28 0.0 X-RAY
 1994-01-31 TYR A:217 A:225 4.0 0.017 -115.8 29.6 4.0 0.017 0.0 PLA
 2.895
 OH
 O3
TYR B:217 B:225 5.0 0.022 -140.8 34.8 5.0 0.022 0.0 PLA
 2.608
 OH
 O3
1tat 1 P00508 86.28 0.0 X-RAY
 1994-01-31 TYR A:217 A:225 12.0 0.052 -111.9 54.0 12.0 0.052 0.0 PLP
 2.471
 OH
 O3
TYR B:217 B:225 15.0 0.065 -120.7 53.9 15.0 0.065 0.0 PLP
 2.397
 OH
 O3
7aat 1 P00508 86.28 0.0 X-RAY
 1993-10-31 TYR A:217 A:225 12.0 0.052 -126.9 29.7 12.0 0.052 0.0 PLP
HOH
 2.492
2.913
 OH
N
 O3
O
TYR B:217 B:225 12.0 0.052 -127.4 30.4 12.0 0.052 0.0 PLP
HOH
 2.586
2.903
 OH
OH
 O3
O
8aat 1 P00508 86.28 0.0 X-RAY
 1993-10-31 TYR A:217 A:225 10.0 0.043 -130.8 35.8 10.0 0.043 0.0 PLP
HOH
 2.824
2.947
 OH
N
 O3
O
TYR B:217 B:225 11.0 0.048 -124.4 28.1 11.0 0.048 0.0 PLP
HOH
 2.746
2.865
 OH
N
 O3
O
9aat 1 P00508 86.28 0.0 X-RAY
 1993-10-31 TYR A:217 A:225 15.0 0.065 -136.2 38.5 15.0 0.065 0.0 PMP
HOH
 2.352
2.889
 OH
N
 O3
O
TYR B:217 B:225 17.0 0.074 -126.4 32.5 17.0 0.074 0.0 PMP
HOH
 2.538
2.882
 OH
N
 O3
O
1aka 1 P00508 86.03 0.0 X-RAY
 1994-07-31 TYR A:217 A:225 18.0 0.078 -131.2 34.0 18.0 0.078 0.0 PLP
HOH
 2.363
2.828
 OH
N
 O3
O
TYR B:217 B:225 19.0 0.083 -130.8 29.9 19.0 0.083 0.0 PO4
HOH
 6.376
3.021
 OH
N
 O4
O
1akb 1 P00508 86.03 0.0 X-RAY
 1994-07-31 TYR A:217 A:225 4.0 0.017 -121.3 42.3 4.0 0.017 0.0 PPD
HOH
 2.555
2.741
 OH
N
 O3
O
1akc 1 P00508 86.03 0.0 X-RAY
 1994-07-31 TYR A:217 A:225 18.0 0.078 -118.0 39.2 18.0 0.078 0.0 PPE
HOH
 2.427
2.991
 OH
N
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00505-f1 1 P00505 100.0 0.0 TYR A:246 A:246 9.0 0.039 -130.2 15.1