Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239260 . G A CCDS32489.1:NM_001025200.3:c.467aCc>aTc_NP_001020371.3:p.156T>I Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
1993-10-31 THR A:138 E:138 2.0 0.014 E -137.0 151.9 2.0 0.014 0.0 HOH
3.002
OG1
O
1cgi 1 P00766 80.82 1e-146 X-RAY
1993-10-31 THR A:138 E:138 7.0 0.05 E -124.6 143.9 7.0 0.05 0.0 HOH
2.707
OG1
O
1cgj 1 P00766 80.82 1e-146 X-RAY
1993-10-31 THR A:138 E:138 7.0 0.05 E -129.7 135.8 7.0 0.05 0.0 HOH
2.798
OG1
O
1chg 1 P00766 80.82 1e-146 X-RAY
1976-11-22 THR A:138 A:138 0.0 0.0 E -112.0 139.2 0.0 0.0 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
2000-05-17 THR A:138 A:138 0.0 0.0 E -127.0 137.7 0.0 0.0 0.0 HOH
6.829
OG1
O
1gcd 1 P00766 80.82 1e-146 X-RAY
1994-06-22 THR A:138 A:138 1.0 0.007 E -122.3 143.4 1.0 0.007 0.0 DEP
HOH
8.832
2.981
OG1
OG1
C2
O
1gl0 1 P00766 80.82 1e-146 X-RAY
2001-11-28 THR A:138 E:138 2.0 0.014 E -127.1 152.3 2.0 0.014 0.0 HOH
5.145
C
O
1gl1 1 P00766 80.82 1e-146 X-RAY
2001-11-28 THR A:138 A:138 3.0 0.021 E -127.7 144.0 3.0 0.021 0.0 HOH
2.749
OG1
O
THR B:138 B:138 2.0 0.014 E -132.3 144.4 NA NA NA
THR C:138 C:138 3.0 0.021 E -128.6 150.2 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
2001-12-05 THR A:138 1:138 2.0 0.014 E -128.7 148.1 2.0 0.014 0.0 SN1
HOH
7.737
2.759
OG1
OG1
OH2
O
1oxg 1 P00766 80.82 1e-146 X-RAY
2004-05-18 THR A:138 A:138 1.0 0.007 E -124.8 140.9 1.0 0.007 0.0 HOH
2.845
OG1
O
1p2m 1 P00766 80.82 1e-146 X-RAY
2004-04-20 THR A:138 A:138 2.0 0.014 E -127.2 148.0 2.0 0.014 0.0 HOH
2.750
OG1
O
THR C:138 C:138 2.0 0.014 E -124.5 150.0 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
2004-04-20 THR A:138 A:138 1.0 0.007 E -128.8 147.6 1.0 0.007 0.0 HOH
2.782
OG1
O
THR C:138 C:138 2.0 0.014 E -126.4 149.9 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
2004-04-20 THR A:138 A:138 2.0 0.014 E -129.6 149.0 2.0 0.014 0.0 HOH
5.223
C
O
THR C:138 C:138 3.0 0.021 E -121.8 150.5 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
2004-04-20 THR A:138 A:138 1.0 0.007 E -127.5 149.1 1.0 0.007 0.0 HOH
2.737
OG1
O
THR C:138 C:138 2.0 0.014 E -128.1 148.5 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
2005-03-08 THR A:138 A:138 2.0 0.014 E -126.9 148.6 2.0 0.014 0.0 HOH
2.801
OG1
O
THR C:138 C:138 2.0 0.014 E -127.4 147.6 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
2005-03-08 THR A:138 A:138 2.0 0.014 E -127.0 149.0 2.0 0.014 0.0 HOH
2.708
OG1
O
THR C:138 C:138 3.0 0.021 E -128.7 148.7 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
2005-03-08 THR A:138 A:138 2.0 0.014 E -126.3 149.3 2.0 0.014 0.0 HOH
2.693
OG1
O
THR C:138 C:138 2.0 0.014 E -127.1 148.8 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
2005-03-08 THR A:138 A:138 1.0 0.007 E -127.4 148.1 1.0 0.007 0.0 HOH
2.758
OG1
O
THR C:138 C:138 2.0 0.014 E -128.5 147.0 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
2005-03-08 THR A:138 A:138 2.0 0.014 E -126.9 148.9 2.0 0.014 0.0 HOH
2.733
OG1
O
THR C:138 C:138 1.0 0.007 E -125.5 150.1 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
1987-04-16 THR A:138 A:138 0.0 0.0 E -117.8 133.2 0.0 0.0 0.0 HOH
2.697
OG1
O
THR B:138 B:138 0.0 0.0 E -121.1 139.9 0.0 0.0 0.0 HOH
3.043
OG1
O
2y6t 1 P00766 80.82 1e-146 X-RAY
2011-04-20 THR A:138 A:138 1.0 0.007 E -115.3 143.5 1.0 0.007 0.0 HOH
9.526
O
O
THR B:138 B:138 2.0 0.014 E -127.3 139.8 2.0 0.014 0.0 HOH
9.326
O
O
THR C:138 C:138 2.0 0.014 E -124.2 145.1 NA NA NA
THR D:138 D:138 2.0 0.014 E -116.3 134.3 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
2012-08-01 THR A:138 A:138 2.0 0.014 E -124.9 153.4 2.0 0.014 0.0 HOH
2.736
OG1
O
THR C:138 B:138 1.0 0.007 E -123.2 149.9 NA NA NA
THR E:138 C:138 2.0 0.014 E -130.1 149.2 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
2014-07-23 THR A:138 A:138 1.0 0.007 E -120.1 153.5 1.0 0.007 0.0 5BF
HOH
8.185
7.566
OG1
O
C45
O
THR B:138 B:138 1.0 0.007 E -121.7 149.8 NA NA NA
THR C:138 C:138 1.0 0.007 E -116.7 157.4 NA NA NA
THR D:138 D:138 1.0 0.007 E -121.5 149.0 1.0 0.007 0.0 5BF
HOH
8.751
2.920
OG1
OG1
C41
O
5j4q 1 P00766 80.82 1e-146 X-RAY
2017-04-12 THR A:138 A:138 2.0 0.014 E -127.4 150.2 2.0 0.014 0.0 HOH
5.612
C
O
5j4s 1 P00766 80.82 1e-146 X-RAY
2017-04-12 THR A:138 A:138 1.0 0.007 E -125.4 147.0 1.0 0.007 0.0 HOH
2.728
OG1
O
7kty 1 P00766 80.82 1e-146 X-RAY
2021-03-10 THR A:138 A:138 0.0 0.0 E -111.5 139.8 0.0 0.0 0.0 HOH
3.018
OG1
O
7ktz 1 P00766 80.82 1e-146 X-RAY
2021-03-10 THR A:138 A:138 0.0 0.0 E -114.2 141.3 0.0 0.0 0.0 HOH
2.501
OG1
O
7ku0 1 P00766 80.82 1e-146 X-RAY
2021-03-10 THR A:138 A:138 0.0 0.0 E -113.9 139.7 0.0 0.0 0.0 HOH
2.364
OG1
O
7ku1 1 P00766 80.82 1e-146 X-RAY
2021-03-10 THR A:138 A:138 0.0 0.0 E -108.2 143.8 0.0 0.0 0.0
7ku2 1 P00766 80.82 1e-146 X-RAY
2021-03-10 THR A:138 A:138 0.0 0.0 E -116.7 144.0 0.0 0.0 0.0 HOH
2.671
OG1
O
7ku3 1 P00766 80.82 1e-146 X-RAY
2021-03-10 THR A:138 A:138 0.0 0.0 E -116.0 142.8 0.0 0.0 0.0 HOH
2.445
OG1
O
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 THR A:123 A:138 136.0 0.971 -140.4 140.0 1.0 0.007 0.964 B:P07338:0.964
HOH
3.460
CG2
O
2jet 2 P07338 89.84 6e-83 X-RAY
2007-09-18 THR B:120 B:138 136.0 0.971 -128.3 141.2 0.0 0.0 0.971 C:P07338:0.971
HOH
2.727
OG1
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 THR B:123 B:138 110.0 0.786 -126.5 146.8 1.0 0.007 0.779 C:P00766:0.779
HOH
2.744
OG1
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 THR B:123 B:138 111.0 0.793 -126.6 146.2 1.0 0.007 0.786 C:P00766:0.786
0FG
HOH
8.676
2.870
OG1
OG1
C3
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 THR B:123 B:138 111.0 0.793 -122.8 139.6 2.0 0.014 0.779 C:P00766:0.779
HOH
2.705
OG1
O
THR F:123 G:138 106.0 0.757 -129.9 147.7 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 THR B:123 B:138 105.0 0.75 -128.4 150.0 1.0 0.007 0.743 C:P00766:0.743
HOH
2.951
OG1
O
THR F:123 G:138 112.0 0.8 -127.2 144.5 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 THR B:123 F:138 112.0 0.8 -129.3 147.1 2.0 0.014 0.786 C:P00766:0.786
HOH
2.792
OG1
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 THR B:123 B:138 112.0 0.8 -129.2 142.5 1.0 0.007 0.793 C:P00766:0.793
HOH
2.807
OG1
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 THR B:123 B:138 109.0 0.779 -125.3 147.1 1.0 0.007 0.772 C:P00766:0.771
APF
HOH
8.301
2.733
OG1
OG1
CP2
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 THR B:123 B:138 109.0 0.779 -128.7 146.2 1.0 0.007 0.772 C:P00766:0.771
FAF
HOH
8.545
2.832
OG1
OG1
CD2
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 THR B:123 F:138 106.0 0.757 -123.9 145.5 1.0 0.007 0.75 C:P00766:0.75
HOH
2.738
OG1
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 THR B:123 F:138 113.0 0.807 -120.4 142.7 1.0 0.007 0.8 F:None:0.007
C:P00766:0.8
ACE
TRP
HEX
HOH
7.036
6.273
8.244
2.661
CG2
OG1
O
OG1
O
O
C6
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 THR B:123 F:138 110.0 0.786 -134.3 139.8 1.0 0.007 0.779 C:P00766:0.779
HOH
2.771
OG1
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 THR B:123 F:138 109.0 0.779 -134.6 147.2 1.0 0.007 0.772 C:P00766:0.771
HEX
HEX
HEX
HOH
8.244
3.037
9.986
2.763
O
O
O
OG1
C6
C2
C1
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 THR B:123 F:138 112.0 0.8 -122.8 150.2 1.0 0.007 0.793 C:P00766:0.793
ISP
HOH
9.386
2.788
OG1
OG1
C1
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 THR B:123 B:138 111.0 0.793 -127.9 141.2 1.0 0.007 0.786 C:P00766:0.786
HOH
2.922
OG1
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 THR B:123 B:138 110.0 0.786 -135.1 146.3 4.0 0.029 0.757 C:P00766:0.757
HOH
4.917
C
O
THR F:123 F:138 114.0 0.814 -133.1 148.1 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 THR B:123 B:138 109.0 0.779 -123.3 149.2 0.0 0.0 0.779 C:P00766:0.779
HOH
2.853
OG1
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:123 B:138 110.0 0.786 -123.1 144.8 1.0 0.007 0.779 C:P00766:0.779
V36
HOH
8.264
2.721
OG1
OG1
C6
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 THR B:123 C:138 113.0 0.807 -123.4 149.0 1.0 0.007 0.8 C:P00766:0.8
HOH
2.756
OG1
O
THR E:123 D:138 111.0 0.793 -124.6 149.7 1.0 0.007 0.786 F:P00766:0.786
HOH
2.755
OG1
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 THR B:123 B:138 111.0 0.793 -145.5 138.6 2.0 0.014 0.779 C:P00766:0.779
TSU
HOH
8.601
2.912
OG1
OG1
C6
O
THR E:123 F:138 112.0 0.8 -145.5 138.6 2.0 0.014 0.786 F:P00766:0.786
TSU
8.601
OG1
C6
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 THR B:123 F:138 115.0 0.821 -124.7 156.9 2.0 0.014 0.807 C:P00766:0.807
HOH
2.478
OG1
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 THR B:123 B:138 113.0 0.807 -127.7 137.7 1.0 0.007 0.8 C:P00766:0.8
HOH
2.599
OG1
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 THR B:123 B:138 112.0 0.8 -130.9 146.9 2.0 0.014 0.786 C:P00766:0.786
HOH
2.749
OG1
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 THR B:123 B:138 110.0 0.786 -120.4 150.2 1.0 0.007 0.779 C:P00766:0.779
BVA
HOH
8.049
2.771
OG1
OG1
C18
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:123 B:138 108.0 0.771 -129.2 146.4 1.0 0.007 0.764 C:P00766:0.764
V35
HOH
8.611
2.791
OG1
OG1
C5
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 THR B:123 B:138 106.0 0.757 -133.6 145.6 1.0 0.007 0.75 C:P00766:0.75
HOH
5.933
OG1
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:123 B:138 110.0 0.786 -121.9 146.4 1.0 0.007 0.779 C:P00766:0.779
OAC
HOH
8.340
4.866
OG1
CG2
OH
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 THR B:123 F:138 110.0 0.786 -130.7 146.5 1.0 0.007 0.779 C:P00766:0.779
HOH
2.703
OG1
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 THR D:123 D:138 108.0 0.771 -123.4 154.9 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:123 B:138 109.0 0.779 -128.4 146.2 1.0 0.007 0.772 C:P00766:0.771
SRB
HOH
7.414
2.850
OG1
OG1
C8
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 THR B:123 B:138 111.0 0.793 -127.3 149.7 1.0 0.007 0.786 C:P00766:0.786
A:P00766:0.007
HOH
2.939
OG1
O
THR E:123 F:138 111.0 0.793 -130.7 146.1 1.0 0.007 0.786 F:P00766:0.786
HOH
2.816
OG1
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:123 F:138 107.0 0.764 -124.7 144.5 1.0 0.007 0.757 C:P00766:0.757
DMC
HOH
8.285
5.315
OG1
OG1
OH
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:123 B:138 109.0 0.779 -137.2 142.1 2.0 0.014 0.765 C:P00766:0.764
SRD
HOH
8.281
2.698
OG1
OG1
C8
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 THR B:123 B:138 107.0 0.764 -132.0 146.6 2.0 0.014 0.75 C:P00766:0.75
HOH
2.720
OG1
O
THR E:123 F:138 116.0 0.829 -124.0 151.8 2.0 0.014 0.815 F:P00766:0.814
HOH
2.884
OG1
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:123 F:138 111.0 0.793 -134.6 131.7 2.0 0.014 0.779 C:P00766:0.779
HOH
5.153
CG2
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -126.0 153.2 1.0 0.007 0.779 C:P00766:0.779
HOH
2.761
OG1
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 109.0 0.779 -123.0 152.1 1.0 0.007 0.772 C:P00766:0.771
HOH
2.750
OG1
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -126.7 153.0 1.0 0.007 0.779 C:P00766:0.779
HOH
2.773
OG1
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 111.0 0.793 -123.5 153.1 1.0 0.007 0.786 C:P00766:0.786
HOH
2.747
OG1
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -126.1 152.6 2.0 0.014 0.772 C:P00766:0.771
HOH
2.755
OG1
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -122.7 152.8 1.0 0.007 0.779 C:P00766:0.779
HOH
2.749
OG1
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 111.0 0.793 -125.9 152.7 2.0 0.014 0.779 C:P00766:0.779
HOH
2.757
OG1
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -122.7 151.6 1.0 0.007 0.779 C:P00766:0.779
HOH
2.758
OG1
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 109.0 0.779 -125.9 153.7 1.0 0.007 0.772 C:P00766:0.771
HOH
2.769
OG1
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -122.9 152.6 1.0 0.007 0.779 C:P00766:0.779
HOH
2.730
OG1
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -125.9 153.4 1.0 0.007 0.779 C:P00766:0.779
HOH
2.765
OG1
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:123 B:138 110.0 0.786 -123.3 151.9 1.0 0.007 0.779 C:P00766:0.779
HOH
2.748
OG1
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 THR B:123 B:138 108.0 0.771 -134.6 144.2 3.0 0.021 0.75 C:P00766:0.75
PBA
HOH
8.035
3.201
OG1
OG1
CD2
O
THR E:123 F:138 112.0 0.8 -134.4 146.1 1.0 0.007 0.793 F:P00766:0.793
PBA
HOH
8.366
2.915
OG1
OG1
CD2
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 THR B:123 B:138 110.0 0.786 -120.7 150.8 1.0 0.007 0.779 C:P00766:0.779
HOH
2.586
OG1
O
THR E:123 E:138 108.0 0.771 -120.7 150.1 NA NA NA
THR H:123 H:138 110.0 0.786 -120.8 150.2 NA NA NA
THR K:123 K:138 109.0 0.779 -121.0 150.0 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:123 F:138 110.0 0.786 -110.9 146.2 1.0 0.007 0.779 C:P00766:0.779
APF
HOH
8.696
2.295
OG1
OG1
CP2
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:123 F:138 112.0 0.8 -124.2 142.1 1.0 0.007 0.793 C:P00766:0.793
LPF
HOH
8.870
2.435
OG1
OG1
CP6
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 THR B:123 B:138 112.0 0.8 -123.8 149.6 1.0 0.007 0.793 C:P00766:0.793
HOH
2.662
OG1
O
THR F:123 b:138 113.0 0.807 -120.4 148.8 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 THR B:123 F:138 111.0 0.793 -123.2 146.4 1.0 0.007 0.786 C:P00766:0.786
HOH
2.688
OG1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 THR A:156 A:156 0.0 0.0 E -127.8 150.4
af-p17538-f1 1 P17538 95.82 0.0 THR A:156 A:156 1.0 0.007 E -130.4 148.4