Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239282 . G A CCDS32489.1:NM_001025200.3:c.445Ccc>Tcc_NP_001020371.3:p.149P>S Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ALA A:131 E:131 49.0 0.426 -60.0 148.5 49.0 0.426 0.0 HOH
 4.014
 CA
 O
1cgi 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ALA A:131 E:131 52.0 0.452 -56.9 136.2 52.0 0.452 0.0 HOH
 7.570
 CA
 O
1cgj 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ALA A:131 E:131 50.0 0.435 -55.3 143.0 50.0 0.435 0.0 HOH
 7.146
 CB
 O
1chg 1 P00766 80.82 1e-146 X-RAY
 1976-11-22 ALA A:131 A:131 43.0 0.374 -52.2 124.3 43.0 0.374 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
 2000-05-17 ALA A:131 A:131 45.0 0.391 -46.2 154.6 45.0 0.391 0.0 HOH
 4.730
 C
 O
1gcd 1 P00766 80.82 1e-146 X-RAY
 1994-06-22 ALA A:131 A:131 44.0 0.383 -64.3 144.5 44.0 0.383 0.0 HOH
 2.855
 N
 O
1gl0 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 ALA A:131 E:131 55.0 0.478 -62.0 149.5 55.0 0.478 0.0 HOH
 6.261
 N
 O
1gl1 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 ALA A:131 A:131 49.0 0.426 -62.6 144.2 49.0 0.426 0.0 HOH
 3.023
 N
 O
ALA B:131 B:131 54.0 0.47 -60.9 149.2 NA NA NA
ALA C:131 C:131 53.0 0.461 -58.0 148.0 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
 2001-12-05 ALA A:131 1:131 49.0 0.426 -64.9 150.4 49.0 0.426 0.0 HOH
 3.013
 N
 O
1oxg 1 P00766 80.82 1e-146 X-RAY
 2004-05-18 ALA A:131 A:131 45.0 0.391 -83.9 150.6 45.0 0.391 0.0 HOH
 4.166
 O
 O
1p2m 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:131 A:131 50.0 0.435 -55.6 145.4 50.0 0.435 0.0 HOH
 5.154
 N
 O
ALA C:131 C:131 52.0 0.452 -46.2 146.9 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:131 A:131 51.0 0.443 -58.0 145.2 51.0 0.443 0.0 HOH
 2.943
 N
 O
ALA C:131 C:131 51.0 0.443 -57.2 144.3 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:131 A:131 52.0 0.452 -63.4 147.2 52.0 0.452 0.0 HOH
 7.369
 C
 O
ALA C:131 C:131 50.0 0.435 -59.5 149.8 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:131 A:131 52.0 0.452 -60.2 149.0 52.0 0.452 0.0 HOH
 2.964
 N
 O
ALA C:131 C:131 51.0 0.443 -50.5 143.6 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:131 A:131 52.0 0.452 -54.1 144.4 52.0 0.452 0.0 HOH
 3.013
 N
 O
ALA C:131 C:131 52.0 0.452 -53.1 145.2 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:131 A:131 51.0 0.443 -58.4 147.8 51.0 0.443 0.0 HOH
 2.976
 N
 O
ALA C:131 C:131 49.0 0.426 -55.4 146.7 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:131 A:131 51.0 0.443 -46.9 143.7 51.0 0.443 0.0 HOH
 2.874
 N
 O
ALA C:131 C:131 54.0 0.47 -41.5 145.1 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:131 A:131 52.0 0.452 -54.6 147.0 52.0 0.452 0.0 HOH
 2.907
 N
 O
ALA C:131 C:131 52.0 0.452 -53.5 145.7 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:131 A:131 50.0 0.435 -53.5 146.1 50.0 0.435 0.0 HOH
 3.528
 CA
 O
ALA C:131 C:131 51.0 0.443 -54.1 148.3 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
 1987-04-16 ALA A:131 A:131 50.0 0.435 -54.5 149.0 50.0 0.435 0.0 HOH
 4.669
 CB
 O
ALA B:131 B:131 49.0 0.426 -67.0 156.8 49.0 0.426 0.0 HOH
 5.167
 C
 O
2y6t 1 P00766 80.82 1e-146 X-RAY
 2011-04-20 ALA A:131 A:131 49.0 0.426 -76.8 152.3 49.0 0.426 0.0 HOH
 7.579
 C
 O
ALA B:131 B:131 50.0 0.435 -68.6 171.3 50.0 0.435 0.0 HOH
 9.051
 N
 O
ALA C:131 C:131 46.0 0.4 -64.6 166.8 NA NA NA
ALA D:131 D:131 45.0 0.391 -63.4 157.0 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
 2012-08-01 ALA A:131 A:131 45.0 0.391 -66.5 143.8 45.0 0.391 0.0 HOH
 2.894
 N
 O
ALA C:131 B:131 50.0 0.435 -71.9 152.6 NA NA NA
ALA E:131 C:131 46.0 0.4 -74.2 156.2 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
 2014-07-23 ALA A:131 A:131 46.0 0.4 -74.8 156.3 46.0 0.4 0.0 HOH
 2.729
 N
 O
ALA B:131 B:131 40.0 0.348 -60.8 152.0 NA NA NA
ALA C:131 C:131 42.0 0.365 -74.9 139.0 NA NA NA
ALA D:131 D:131 44.0 0.383 -75.4 149.1 44.0 0.383 0.0 HOH
 2.659
 N
 O
5j4q 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 ALA A:131 A:131 48.0 0.417 -65.5 143.5 48.0 0.417 0.0 HOH
 2.678
 N
 O
5j4s 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 ALA A:131 A:131 52.0 0.452 -76.9 134.6 52.0 0.452 0.0 HOH
 2.833
 HB1
 O
7kty 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:131 A:131 45.0 0.391 -77.5 146.5 45.0 0.391 0.0 HOH
 3.693
 CA
 O
7ktz 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:131 A:131 43.0 0.374 -69.3 147.5 43.0 0.374 0.0 HOH
 2.921
 N
 O
7ku0 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:131 A:131 44.0 0.383 -71.0 150.0 44.0 0.383 0.0 HOH
 2.781
 N
 O
7ku1 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:131 A:131 61.0 0.53 -65.1 149.4 61.0 0.53 0.0 HOH
 9.288
 N
 O
7ku2 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:131 A:131 49.0 0.426 -78.6 155.3 49.0 0.426 0.0 HOH
 5.536
 N
 O
7ku3 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:131 A:131 45.0 0.391 -67.7 146.0 45.0 0.391 0.0 HOH
 2.862
 N
 O
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 PRO A:116 A:131 71.0 0.49 -46.4 153.2 70.0 0.483 0.007 B:P07338:0.007
 HOH
 4.596
 N
 O
2jet 2 P07338 89.84 6e-83 X-RAY
 2007-09-18 PRO B:113 B:131 59.0 0.407 -73.6 165.1 57.0 0.393 0.014 C:P07338:0.014
 HOH
 6.198
 CA
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 ALA B:116 B:131 52.0 0.452 -62.2 145.7 48.0 0.417 0.035 C:P00766:0.035
 HOH
 5.177
 N
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 ALA B:116 B:131 50.0 0.435 -65.0 143.2 47.0 0.409 0.026 C:P00766:0.026
 HOH
 4.325
 CB
 O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ALA B:116 B:131 50.0 0.435 -63.8 154.4 46.0 0.4 0.035 C:P00766:0.035
 HOH
 3.184
 CA
 O
ALA F:116 G:131 52.0 0.452 -68.9 164.2 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ALA B:116 B:131 59.0 0.513 -51.4 141.4 57.0 0.496 0.017 C:P00766:0.017
 HOH
 7.389
 C
 O
ALA F:116 G:131 59.0 0.513 -64.0 145.5 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 ALA B:116 F:131 56.0 0.487 -61.0 144.8 52.0 0.452 0.035 C:P00766:0.035
 HOH
 5.180
 N
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:116 B:131 54.0 0.47 -73.1 150.2 48.0 0.417 0.053 C:P00766:0.052
 HOH
 2.962
 N
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ALA B:116 B:131 52.0 0.452 -67.7 149.3 47.0 0.409 0.043 C:P00766:0.043
 SO4
HOH
 3.994
3.138
 C
N
 O3
O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ALA B:116 B:131 52.0 0.452 -64.4 145.8 48.0 0.417 0.035 C:P00766:0.035
 HOH
 2.739
 N
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ALA B:116 F:131 53.0 0.461 -60.5 145.8 48.0 0.417 0.044 C:P00766:0.043
 HOH
 2.877
 N
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ALA B:116 F:131 60.0 0.522 -68.1 156.3 53.0 0.461 0.061 C:P00766:0.061
 HOH
 2.813
 N
 O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ALA B:116 F:131 67.0 0.583 -64.7 143.8 63.0 0.548 0.035 C:P00766:0.035
 HOH
 2.955
 N
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ALA B:116 F:131 64.0 0.557 -58.7 143.3 59.0 0.513 0.044 C:P00766:0.043
 HOH
 3.117
 CB
 O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 ALA B:116 F:131 51.0 0.443 -69.9 148.3 48.0 0.417 0.026 C:P00766:0.026
 HOH
 3.784
 C
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 ALA B:116 B:131 59.0 0.513 -62.2 158.4 53.0 0.461 0.052 C:P00766:0.052
 HOH
 7.531
 C
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 ALA B:116 B:131 54.0 0.47 -59.4 138.0 51.0 0.443 0.027 C:P00766:0.026
 HOH
 8.736
 C
 O
ALA F:116 F:131 61.0 0.53 -68.1 137.2 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 ALA B:116 B:131 52.0 0.452 -67.5 147.6 40.0 0.348 0.104 C:P00766:0.043
D:P23827:0.07
 HOH
 2.976
 N
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:116 B:131 53.0 0.461 -63.9 147.7 48.0 0.417 0.044 C:P00766:0.043
 HOH
 5.095
 N
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 ALA B:116 C:131 50.0 0.435 -64.9 149.2 45.0 0.391 0.044 C:P00766:0.043
 HOH
 2.957
 N
 O
ALA E:116 D:131 50.0 0.435 -63.7 146.1 46.0 0.4 0.035 F:P00766:0.035
 HOH
 2.871
 N
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 ALA B:116 B:131 55.0 0.478 -65.9 154.9 50.0 0.435 0.043 C:P00766:0.043
 HOH
 9.346
 N
 O
ALA E:116 F:131 54.0 0.47 -65.9 154.9 50.0 0.435 0.035 F:P00766:0.035
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 ALA B:116 F:131 57.0 0.496 -68.1 141.9 52.0 0.452 0.044 C:P00766:0.043
 HOH
 3.107
 N
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:116 B:131 54.0 0.47 -64.2 148.3 50.0 0.435 0.035 C:P00766:0.035
 HOH
 2.882
 N
 O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 ALA B:116 B:131 52.0 0.452 -59.3 136.9 47.0 0.409 0.043 C:P00766:0.043
 HOH
 4.341
 CB
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 ALA B:116 B:131 46.0 0.4 -78.1 154.1 42.0 0.365 0.035 C:P00766:0.035
 HOH
 2.902
 N
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:116 B:131 52.0 0.452 -66.2 150.4 46.0 0.4 0.052 C:P00766:0.052
 HOH
 3.862
 CA
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 ALA B:116 B:131 57.0 0.496 -59.5 144.1 55.0 0.478 0.018 C:P00766:0.017
 HOH
 3.533
 N
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:116 B:131 53.0 0.461 -75.3 149.5 49.0 0.426 0.035 C:P00766:0.035
 HOH
 5.848
 CB
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:116 F:131 52.0 0.452 -71.8 147.0 47.0 0.409 0.043 C:P00766:0.043
 HOH
 3.102
 N
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 ALA D:116 D:131 46.0 0.4 -73.4 146.0 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:116 B:131 51.0 0.443 -65.8 146.8 45.0 0.391 0.052 C:P00766:0.052
 HOH
 3.722
 CA
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ALA B:116 B:131 51.0 0.443 -69.6 151.8 46.0 0.4 0.043 C:P00766:0.043
 HOH
 6.733
 N
 O
ALA E:116 F:131 56.0 0.487 -67.2 150.8 52.0 0.452 0.035 F:P00766:0.035
 HOH
 6.822
 N
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:116 F:131 53.0 0.461 -59.5 138.1 49.0 0.426 0.035 C:P00766:0.035
 HOH
 5.624
 N
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:116 B:131 50.0 0.435 -62.8 145.0 47.0 0.409 0.026 C:P00766:0.026
 HOH
 5.018
 C
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ALA B:116 B:131 53.0 0.461 -70.4 140.6 49.0 0.426 0.035 C:P00766:0.035
 HOH
 3.508
 CA
 O
ALA E:116 F:131 54.0 0.47 -80.8 151.6 50.0 0.435 0.035 F:P00766:0.035
 HOH
 6.680
 C
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:116 F:131 55.0 0.478 -74.4 143.2 53.0 0.461 0.017 C:P00766:0.017
 HOH
 5.659
 CB
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 51.0 0.443 -74.3 146.1 46.0 0.4 0.043 C:P00766:0.043
 HOH
 2.891
 N
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 48.0 0.417 -74.5 142.6 42.0 0.365 0.052 C:P00766:0.052
 HOH
 2.849
 N
 O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 70.0 0.609 -75.8 146.0 66.0 0.574 0.035 C:P00766:0.035
 HOH
 2.974
 N
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 69.0 0.6 -74.1 144.8 64.0 0.557 0.043 C:P00766:0.043
 HOH
 2.914
 N
 O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 50.0 0.435 -75.2 146.3 45.0 0.391 0.044 C:P00766:0.043
 HOH
 2.865
 N
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 48.0 0.417 -73.3 143.1 44.0 0.383 0.034 C:P00766:0.035
 HOH
 2.916
 N
 O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 50.0 0.435 -74.1 146.2 46.0 0.4 0.035 C:P00766:0.035
 HOH
 2.903
 N
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 48.0 0.417 -72.4 141.7 43.0 0.374 0.043 C:P00766:0.043
 HOH
 2.936
 N
 O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 51.0 0.443 -78.3 148.3 46.0 0.4 0.043 C:P00766:0.043
 HOH
 2.909
 N
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 49.0 0.426 -75.2 145.1 44.0 0.383 0.043 C:P00766:0.043
 HOH
 2.859
 N
 O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 52.0 0.452 -76.7 148.8 47.0 0.409 0.043 C:P00766:0.043
 HOH
 3.071
 N
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:116 B:131 49.0 0.426 -75.7 143.9 44.0 0.383 0.043 C:P00766:0.043
 HOH
 2.841
 N
 O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 ALA B:116 B:131 56.0 0.487 -75.7 149.3 51.0 0.443 0.044 C:P00766:0.043
 HOH
 2.753
 N
 O
ALA E:116 F:131 57.0 0.496 -67.8 148.6 51.0 0.443 0.053 F:P00766:0.052
 HOH
 3.900
 CA
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 ALA B:116 B:131 51.0 0.443 -74.4 156.2 47.0 0.409 0.034 C:P00766:0.035
 HOH
 2.972
 N
 O
ALA E:116 E:131 52.0 0.452 -74.3 156.5 NA NA NA
ALA H:116 H:131 51.0 0.443 -73.8 156.0 NA NA NA
ALA K:116 K:131 52.0 0.452 -74.0 157.2 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:116 F:131 52.0 0.452 -59.4 142.6 48.0 0.417 0.035 C:P00766:0.035
 HOH
 2.861
 N
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:116 F:131 54.0 0.47 -75.3 155.0 11.0 0.096 0.374 C:P00766:0.043
C:P00766:0.322
 HOH
 2.525
 N
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 ALA B:116 B:131 47.0 0.409 -64.8 144.0 43.0 0.374 0.035 C:P00766:0.035
 HOH
 2.860
 N
 O
ALA F:116 b:131 49.0 0.426 -63.7 142.8 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 ALA B:116 F:131 48.0 0.417 -69.1 137.2 45.0 0.391 0.026 C:P00766:0.026
 HOH
 2.777
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 PRO A:149 A:149 73.0 0.503 -64.7 156.1
af-p17538-f1 1 P17538 95.82 0.0 PRO A:149 A:149 70.0 0.483 -57.9 155.4