Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239288 . C A CCDS32489.1:NM_001025200.3:c.439Gac>Tac_NP_001020371.3:p.147D>Y Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ASP A:129 E:129 121.0 0.807 -144.2 135.2 121.0 0.807 0.0 HOH
 4.219
 OD1
 O
1cgi 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ASP A:129 E:129 143.0 0.953 -128.2 108.2 143.0 0.953 0.0 HOH
 3.737
 OD2
 O
1cgj 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ASP A:129 E:129 142.0 0.947 -129.5 113.2 142.0 0.947 0.0 HOH
 3.865
 OD1
 O
1chg 1 P00766 80.82 1e-146 X-RAY
 1976-11-22 ASP A:129 A:129 130.0 0.867 -125.0 172.4 130.0 0.867 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
 2000-05-17 ASP A:129 A:129 115.0 0.767 -142.0 95.5 115.0 0.767 0.0 HOH
 3.491
 CA
 O
1gcd 1 P00766 80.82 1e-146 X-RAY
 1994-06-22 ASP A:129 A:129 127.0 0.847 -107.6 120.2 127.0 0.847 0.0 HOH
 2.699
 O
 O
1gl0 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 ASP A:129 E:129 123.0 0.82 -125.5 130.5 123.0 0.82 0.0 HOH
 2.969
 OD2
 O
1gl1 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 ASP A:129 A:129 116.0 0.773 -110.8 112.9 116.0 0.773 0.0 HOH
 2.749
 OD1
 O
ASP B:129 B:129 140.0 0.933 -129.6 116.0 NA NA NA
ASP C:129 C:129 131.0 0.873 -132.9 135.4 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
 2001-12-05 ASP A:129 1:129 116.0 0.773 -115.8 129.1 116.0 0.773 0.0 HOH
 3.457
 O
 O
1oxg 1 P00766 80.82 1e-146 X-RAY
 2004-05-18 ASP A:129 A:129 126.0 0.84 -113.8 111.5 126.0 0.84 0.0 HOH
 2.950
 O
 O
1p2m 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ASP A:129 A:129 141.0 0.94 -124.0 105.3 141.0 0.94 0.0 HOH
 3.398
 CA
 O
ASP C:129 C:129 143.0 0.953 -128.0 117.0 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ASP A:129 A:129 140.0 0.933 -120.7 105.3 140.0 0.933 0.0 HOH
 2.882
 N
 O
ASP C:129 C:129 141.0 0.94 -119.5 122.7 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ASP A:129 A:129 142.0 0.947 -123.8 108.9 142.0 0.947 0.0 HOH
 6.008
 CA
 O
ASP C:129 C:129 138.0 0.92 -127.2 113.6 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ASP A:129 A:129 144.0 0.96 -121.5 102.2 144.0 0.96 0.0 HOH
 2.902
 N
 O
ASP C:129 C:129 140.0 0.933 -118.7 121.3 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ASP A:129 A:129 141.0 0.94 -123.6 104.8 141.0 0.94 0.0 HOH
 2.860
 N
 O
ASP C:129 C:129 141.0 0.94 -125.5 111.1 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ASP A:129 A:129 140.0 0.933 -119.9 103.8 140.0 0.933 0.0 HOH
 3.044
 N
 O
ASP C:129 C:129 140.0 0.933 -119.9 121.7 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ASP A:129 A:129 141.0 0.94 -124.9 105.3 141.0 0.94 0.0 HOH
 2.901
 N
 O
ASP C:129 C:129 144.0 0.96 -125.5 119.4 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ASP A:129 A:129 143.0 0.953 -122.8 106.4 143.0 0.953 0.0 HOH
 2.981
 N
 O
ASP C:129 C:129 140.0 0.933 -122.1 122.4 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ASP A:129 A:129 141.0 0.94 -123.3 105.5 141.0 0.94 0.0 HOH
 2.910
 N
 O
ASP C:129 C:129 141.0 0.94 -123.0 118.9 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
 1987-04-16 ASP A:129 A:129 129.0 0.86 -109.4 122.9 129.0 0.86 0.0 HOH
 3.488
 OD1
 O
ASP B:129 B:129 120.0 0.8 -109.5 123.0 120.0 0.8 0.0 HOH
 5.080
 CB
 O
2y6t 1 P00766 80.82 1e-146 X-RAY
 2011-04-20 ASP A:129 A:129 134.0 0.893 -120.6 118.1 134.0 0.893 0.0
ASP B:129 B:129 132.0 0.88 -112.3 130.1 132.0 0.88 0.0 HOH
 7.660
 C
 O
ASP C:129 C:129 128.0 0.853 -105.4 131.7 NA NA NA
ASP D:129 D:129 139.0 0.927 -109.8 110.1 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
 2012-08-01 ASP A:129 A:129 136.0 0.907 -113.4 116.7 136.0 0.907 0.0 HOH
 2.616
 OD2
 O
ASP C:129 B:129 124.0 0.827 -119.4 114.5 NA NA NA
ASP E:129 C:129 119.0 0.793 -113.0 115.8 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
 2014-07-23 ASP A:129 A:129 121.0 0.807 -102.8 114.9 121.0 0.807 0.0 HOH
 2.923
 O
 O
ASP B:129 B:129 129.0 0.86 -109.8 95.8 NA NA NA
ASP C:129 C:129 143.0 0.953 -94.0 109.2 NA NA NA
ASP D:129 D:129 134.0 0.893 -110.8 98.5 134.0 0.893 0.0 HOH
 2.387
 OD2
 O
5j4q 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 ASP A:129 A:129 137.0 0.913 -113.9 119.0 137.0 0.913 0.0 HOH
 3.213
 O
 O
5j4s 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 ASP A:129 A:129 145.0 0.967 -114.0 105.3 145.0 0.967 0.0 HOH
 2.885
 HA
 O
7kty 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ASP A:129 A:129 136.0 0.907 -116.0 122.1 136.0 0.907 0.0 HOH
 3.450
 CA
 O
7ktz 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ASP A:129 A:129 128.0 0.853 -109.5 115.9 128.0 0.853 0.0 HOH
 2.730
 O
 O
7ku0 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ASP A:129 A:129 136.0 0.907 -111.6 115.6 136.0 0.907 0.0 HOH
 2.687
 O
 O
7ku1 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ASP A:129 A:129 158.0 1.0 -123.2 107.9 158.0 1.0 0.0 HOH
 7.955
 C
 O
7ku2 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ASP A:129 A:129 139.0 0.927 -116.2 111.1 139.0 0.927 0.0 HOH
 3.548
 CA
 O
7ku3 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ASP A:129 A:129 138.0 0.92 -115.3 114.8 138.0 0.92 0.0 HOH
 3.263
 O
 O
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 ASP A:114 A:129 142.0 0.947 -144.7 139.3 95.0 0.633 0.314 B:P07338:0.313
 HOH
 3.760
 OD1
 O
2jet 2 P07338 89.84 6e-83 X-RAY
 2007-09-18 ASP B:111 B:129 132.0 0.88 -139.3 136.7 104.0 0.693 0.187 C:P07338:0.187
 HOH
 3.732
 OD1
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 ASP B:114 B:129 140.0 0.933 -111.8 124.9 127.0 0.847 0.086 C:P00766:0.087
 HOH
 3.621
 CA
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 ASP B:114 B:129 138.0 0.92 -108.2 130.5 118.0 0.787 0.133 C:P00766:0.133
 HOH
 3.236
 CA
 O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ASP B:114 B:129 141.0 0.94 -117.9 101.1 138.0 0.92 0.02 C:P00766:0.02
 HOH
 2.716
 OD1
 O
ASP F:114 G:129 141.0 0.94 -111.4 119.2 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ASP B:114 B:129 143.0 0.953 -137.5 99.5 142.0 0.947 0.006 C:P00766:0.007
 HOH
 6.097
 OD1
 O
ASP F:114 G:129 151.0 1.0 -119.8 114.8 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 ASP B:114 F:129 135.0 0.9 -125.1 133.8 135.0 0.9 0.0 HOH
 2.601
 O
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ASP B:114 B:129 140.0 0.933 -108.9 118.6 122.0 0.813 0.12 C:P00766:0.12
 HOH
 3.208
 N
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ASP B:114 B:129 137.0 0.913 -106.3 126.8 135.0 0.9 0.013 C:P00766:0.013
 SO4
HOH
 5.032
2.920
 OD1
N
 O1
O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ASP B:114 B:129 136.0 0.907 -116.2 131.2 130.0 0.867 0.04 C:P00766:0.04
 HOH
 3.057
 N
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ASP B:114 F:129 134.0 0.893 -114.3 132.5 117.0 0.78 0.113 C:P00766:0.113
 HOH
 3.107
 N
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ASP B:114 F:129 143.0 0.953 -123.0 127.9 123.0 0.82 0.133 C:P00766:0.133
 HOH
 3.441
 O
 O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ASP B:114 F:129 143.0 0.953 -121.3 133.3 124.0 0.827 0.126 C:P00766:0.127
 HOH
 2.748
 OD1
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ASP B:114 F:129 145.0 0.967 -104.7 133.8 128.0 0.853 0.114 C:P00766:0.113
 HOH
 2.690
 OD1
 O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 ASP B:114 F:129 135.0 0.9 -106.6 127.2 120.0 0.8 0.1 C:P00766:0.1
 HOH
 5.445
 C
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 ASP B:114 B:129 137.0 0.913 -126.2 133.6 131.0 0.873 0.04 C:P00766:0.04
 HOH
 4.972
 N
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 ASP B:114 B:129 139.0 0.927 -117.0 118.3 131.0 0.873 0.054 C:P00766:0.053
 HOH
 4.533
 N
 O
ASP F:114 F:129 139.0 0.927 -142.2 129.7 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 ASP B:114 B:129 145.0 0.967 -119.3 125.4 83.0 0.553 0.414 C:P00766:0.093
D:P23827:0.32
 HOH
 2.780
 O
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:114 B:129 146.0 0.973 -114.7 128.1 123.0 0.82 0.153 C:P00766:0.153
 HOH
 3.763
 CA
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 ASP B:114 C:129 135.0 0.9 -115.2 123.9 124.0 0.827 0.073 C:P00766:0.073
 HOH
 2.656
 O
 O
ASP E:114 D:129 139.0 0.927 -113.9 117.7 131.0 0.873 0.054 F:P00766:0.053
 HOH
 2.758
 O
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 ASP B:114 B:129 130.0 0.867 -110.0 131.4 127.0 0.847 0.02 C:P00766:0.02
 HOH
 7.997
 C
 O
ASP E:114 F:129 130.0 0.867 -110.0 131.4 126.0 0.84 0.027 F:P00766:0.027
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 ASP B:114 F:129 148.0 0.987 -108.5 121.3 133.0 0.887 0.1 C:P00766:0.1
 HOH
 2.509
 N
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ASP B:114 B:129 141.0 0.94 -115.0 124.3 129.0 0.86 0.08 C:P00766:0.08
 HOH
 3.003
 O
 O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 ASP B:114 B:129 138.0 0.92 -99.4 126.2 119.0 0.793 0.127 C:P00766:0.127
 HOH
 3.127
 OD1
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 ASP B:114 B:129 138.0 0.92 -110.1 119.3 121.0 0.807 0.113 C:P00766:0.113
 HOH
 2.648
 OD1
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:114 B:129 136.0 0.907 -103.5 124.8 115.0 0.767 0.14 C:P00766:0.14
 HOH
 3.790
 C
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 ASP B:114 B:129 146.0 0.973 -125.2 119.3 139.0 0.927 0.046 C:P00766:0.047
 HOH
 2.933
 CB
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:114 B:129 139.0 0.927 -106.9 144.6 122.0 0.813 0.114 C:P00766:0.113
 HOH
 2.947
 OD2
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ASP B:114 F:129 139.0 0.927 -109.0 120.7 122.0 0.813 0.114 C:P00766:0.113
 HOH
 3.255
 O
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 ASP D:114 D:129 139.0 0.927 -104.5 114.8 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:114 B:129 138.0 0.92 -109.2 124.5 120.0 0.8 0.12 C:P00766:0.12
 HOH
 3.681
 CA
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ASP B:114 B:129 134.0 0.893 -116.8 127.1 130.0 0.867 0.026 C:P00766:0.027
 HOH
 5.522
 CA
 O
ASP E:114 F:129 139.0 0.927 -115.6 127.0 129.0 0.86 0.067 F:P00766:0.067
 HOH
 5.676
 CA
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:114 F:129 138.0 0.92 -98.5 145.5 117.0 0.78 0.14 C:P00766:0.14
 HOH
 3.412
 OD2
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:114 B:129 135.0 0.9 -109.3 126.9 119.0 0.793 0.107 C:P00766:0.107
 HOH
 4.739
 N
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ASP B:114 B:129 133.0 0.887 -109.1 134.3 130.0 0.867 0.02 C:P00766:0.02
 HOH
 2.374
 OD1
 O
ASP E:114 F:129 135.0 0.9 -127.7 109.7 133.0 0.887 0.013 F:P00766:0.013
 HOH
 4.746
 N
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:114 F:129 140.0 0.933 -115.3 139.5 125.0 0.833 0.1 C:P00766:0.1
 HOH
 3.189
 OD2
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 138.0 0.92 -111.8 127.1 124.0 0.827 0.093 C:P00766:0.093
 HOH
 3.603
 O
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 139.0 0.927 -108.6 123.1 122.0 0.813 0.114 C:P00766:0.113
 HOH
 2.440
 OD2
 O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 153.0 1.0 -117.1 131.8 139.0 0.927 0.073 C:P00766:0.093
 HOH
 3.826
 O
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 152.0 1.0 -115.0 134.2 131.0 0.873 0.127 C:P00766:0.14
 HOH
 3.340
 O
 O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 137.0 0.913 -111.1 125.8 124.0 0.827 0.086 C:P00766:0.087
 HOH
 3.460
 O
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 139.0 0.927 -111.6 123.1 122.0 0.813 0.114 C:P00766:0.113
 HOH
 2.957
 N
 O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 140.0 0.933 -111.5 125.5 127.0 0.847 0.086 C:P00766:0.087
 HOH
 3.546
 O
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 139.0 0.927 -110.3 124.1 121.0 0.807 0.12 C:P00766:0.12
 HOH
 2.857
 N
 O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 138.0 0.92 -110.4 126.5 124.0 0.827 0.093 C:P00766:0.093
 HOH
 2.914
 N
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 139.0 0.927 -107.2 125.4 139.0 0.927 0.0 HOH
 2.410
 OD2
 O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 136.0 0.907 -109.8 127.3 117.0 0.78 0.127 C:P00766:0.127
 HOH
 3.464
 CA
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:114 B:129 139.0 0.927 -105.9 125.6 138.0 0.92 0.007 C:P00766:0.007
 HOH
 2.376
 OD2
 O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 ASP B:114 B:129 131.0 0.873 -127.3 129.7 126.0 0.84 0.033 C:P00766:0.033
 HOH
 2.876
 OD1
 O
ASP E:114 F:129 135.0 0.9 -120.9 111.8 135.0 0.9 0.0 HOH
 2.685
 OD2
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 ASP B:114 B:129 142.0 0.947 -111.0 103.7 142.0 0.947 0.0 HOH
 2.745
 O
 O
ASP E:114 E:129 141.0 0.94 -110.3 106.0 NA NA NA
ASP H:114 H:129 143.0 0.953 -110.4 105.1 NA NA NA
ASP K:114 K:129 142.0 0.947 -109.4 105.2 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:114 F:129 144.0 0.96 -104.3 138.9 139.0 0.927 0.033 C:P00766:0.033
 HOH
 3.660
 O
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:114 F:129 135.0 0.9 -115.5 135.9 105.0 0.7 0.2 C:P00766:0.12
C:P00766:0.08
 HOH
 2.179
 OD2
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 ASP B:114 B:129 140.0 0.933 -107.6 111.1 130.0 0.867 0.066 C:P00766:0.067
 HOH
 2.388
 OD2
 O
ASP F:114 b:129 140.0 0.933 -109.1 117.2 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 ASP B:114 F:129 140.0 0.933 -103.9 131.7 135.0 0.9 0.033 C:P00766:0.033
 HOH
 2.399
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 ASP A:147 A:147 136.0 0.907 -109.7 124.3
af-p17538-f1 1 P17538 95.82 0.0 ASP A:147 A:147 129.0 0.86 -99.0 135.2