Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239818 . C A CCDS32489.1:NM_001025200.3:c.229Ggg>Tgg_NP_001020371.3:p.77G>W Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
1993-10-31 GLY A:59 E:59 53.0 0.707 63.2 35.9 50.0 0.667 0.04 B:P01051:0.04
HOH
3.216
N
O
1cgi 1 P00766 80.82 1e-146 X-RAY
1993-10-31 GLY A:59 E:59 48.0 0.64 66.6 53.4 43.0 0.573 0.067 B:P00995:0.067
HOH
9.883
N
O
1cgj 1 P00766 80.82 1e-146 X-RAY
1993-10-31 GLY A:59 E:59 52.0 0.693 64.5 40.2 44.0 0.587 0.106 B:P00995:0.107
HOH
6.376
N
O
1chg 1 P00766 80.82 1e-146 X-RAY
1976-11-22 GLY A:59 A:59 61.0 0.813 43.4 26.3 61.0 0.813 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
2000-05-17 GLY A:59 A:59 56.0 0.747 43.6 45.9 56.0 0.747 0.0 HOH
3.659
CA
O
1gcd 1 P00766 80.82 1e-146 X-RAY
1994-06-22 GLY A:59 A:59 53.0 0.707 54.9 39.4 8.0 0.107 0.6 A:P00766:0.6
DEP
HOH
9.825
2.836
N
O
O2
O
1gl0 1 P00766 80.82 1e-146 X-RAY
2001-11-28 GLY A:59 E:59 54.0 0.72 48.1 65.0 54.0 0.72 0.0 HOH
3.690
O
O
1gl1 1 P00766 80.82 1e-146 X-RAY
2001-11-28 GLY A:59 A:59 51.0 0.68 61.7 42.8 50.0 0.667 0.013 D:P80060:0.013
HOH
3.175
N
O
GLY B:59 B:59 52.0 0.693 59.3 44.9 NA NA NA
GLY C:59 C:59 51.0 0.68 53.8 45.5 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
2001-12-05 GLY A:59 1:59 52.0 0.693 57.1 42.4 52.0 0.693 0.0 SN1
HOH
9.402
3.262
N
N
O2
O
1oxg 1 P00766 80.82 1e-146 X-RAY
2004-05-18 GLY A:59 A:59 52.0 0.693 63.6 31.7 52.0 0.693 0.0 SO4
HOH
7.055
2.648
O
O
O1
O
1p2m 1 P00766 80.82 1e-146 X-RAY
2004-04-20 GLY A:59 A:59 50.0 0.667 56.5 37.6 50.0 0.667 0.0 SO4
HOH
6.290
2.941
CA
O
O4
O
GLY C:59 C:59 50.0 0.667 56.4 39.9 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
2004-04-20 GLY A:59 A:59 51.0 0.68 57.0 37.2 51.0 0.68 0.0 SO4
HOH
7.167
2.606
N
O
O1
O
GLY C:59 C:59 50.0 0.667 57.5 39.3 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
2004-04-20 GLY A:59 A:59 51.0 0.68 55.0 38.7 50.0 0.667 0.013 B:P00974:0.013
SO4
HOH
6.804
2.987
CA
O
O4
O
GLY C:59 C:59 50.0 0.667 56.4 39.3 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
2004-04-20 GLY A:59 A:59 50.0 0.667 57.0 38.8 50.0 0.667 0.0 SO4
TRS
HOH
6.391
3.012
2.668
CA
O
O
O1
N
O
GLY C:59 C:59 50.0 0.667 55.5 38.9 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
2005-03-08 GLY A:59 A:59 50.0 0.667 57.2 37.9 49.0 0.653 0.014 B:P00974:0.013
SO4
HOH
6.461
2.641
CA
O
O4
O
GLY C:59 C:59 50.0 0.667 56.7 37.9 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
2005-03-08 GLY A:59 A:59 51.0 0.68 57.7 38.4 50.0 0.667 0.013 B:P00974:0.013
SO4
HOH
7.187
2.720
CA
O
O1
O
GLY C:59 C:59 50.0 0.667 57.0 38.8 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
2005-03-08 GLY A:59 A:59 51.0 0.68 56.9 38.8 50.0 0.667 0.013 B:P00974:0.013
SO4
HOH
6.368
2.633
CA
O
O1
O
GLY C:59 C:59 50.0 0.667 56.9 38.0 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
2005-03-08 GLY A:59 A:59 51.0 0.68 56.7 37.7 50.0 0.667 0.013 B:P00974:0.013
SO4
HOH
6.513
2.748
CA
O
O4
O
GLY C:59 C:59 50.0 0.667 56.0 38.1 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
2005-03-08 GLY A:59 A:59 50.0 0.667 56.2 38.7 50.0 0.667 0.0 SO4
HOH
6.928
2.777
CA
O
O4
O
GLY C:59 C:59 50.0 0.667 55.7 40.1 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
1987-04-16 GLY A:59 A:59 53.0 0.707 63.0 32.5 53.0 0.707 0.0 HOH
2.981
N
O
GLY B:59 B:59 54.0 0.72 61.0 35.2 54.0 0.72 0.0 HOH
3.011
O
O
2y6t 1 P00766 80.82 1e-146 X-RAY
2011-04-20 GLY A:59 A:59 50.0 0.667 65.5 31.6 44.0 0.587 0.08 E:B1JSA0:0.08
HOH
3.691
CA
O
GLY B:59 B:59 51.0 0.68 62.5 43.4 51.0 0.68 0.0
GLY C:59 C:59 55.0 0.733 53.0 39.4 NA NA NA
GLY D:59 D:59 50.0 0.667 68.0 42.4 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
2012-08-01 GLY A:59 A:59 51.0 0.68 59.6 36.9 51.0 0.68 0.0 HOH
2.731
O
O
GLY C:59 B:59 53.0 0.707 59.1 36.2 NA NA NA
GLY E:59 C:59 52.0 0.693 55.7 37.2 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
2014-07-23 GLY A:59 A:59 47.0 0.627 53.1 40.9 47.0 0.627 0.0 5BF
HOH
9.162
3.310
N
N
C04
O
GLY B:59 B:59 51.0 0.68 55.0 40.9 NA NA NA
GLY C:59 C:59 49.0 0.653 45.8 52.4 NA NA NA
GLY D:59 D:59 48.0 0.64 61.8 38.0 39.0 0.52 0.12 A:P00766:0.12
5BF
HOH
9.373
3.056
N
N
C04
O
5j4q 1 P00766 80.82 1e-146 X-RAY
2017-04-12 GLY A:59 A:59 50.0 0.667 69.2 40.4 50.0 0.667 0.0 HOH
3.340
C
O
5j4s 1 P00766 80.82 1e-146 X-RAY
2017-04-12 GLY A:59 A:59 49.0 0.653 65.8 31.3 49.0 0.653 0.0 HOH
3.109
H
O
7kty 1 P00766 80.82 1e-146 X-RAY
2021-03-10 GLY A:59 A:59 52.0 0.693 57.5 41.2 24.0 0.32 0.373 A:P00766:0.373
SO4
SO4
SO4
HOH
3.545
7.299
3.496
3.245
CA
O
O
N
O2
O2
O1
O
7ktz 1 P00766 80.82 1e-146 X-RAY
2021-03-10 GLY A:59 A:59 49.0 0.653 58.0 38.8 19.0 0.253 0.4 A:P00766:0.4
SO4
SO4
SO4
HOH
3.406
7.003
3.656
2.965
O
O
CA
O
O4
O2
O3
O
7ku0 1 P00766 80.82 1e-146 X-RAY
2021-03-10 GLY A:59 A:59 48.0 0.64 58.9 38.9 19.0 0.253 0.387 A:P00766:0.387
SO4
SO4
SO4
HOH
3.779
7.053
3.354
2.694
CA
O
O
O
O2
O2
O1
O
7ku1 1 P00766 80.82 1e-146 X-RAY
2021-03-10 GLY A:59 A:59 50.0 0.667 52.6 45.3 36.0 0.48 0.187 A:P00766:0.187
7ku2 1 P00766 80.82 1e-146 X-RAY
2021-03-10 GLY A:59 A:59 53.0 0.707 56.7 44.4 39.0 0.52 0.187 A:P00766:0.187
HOH
3.131
N
O
7ku3 1 P00766 80.82 1e-146 X-RAY
2021-03-10 GLY A:59 A:59 50.0 0.667 56.9 39.2 18.0 0.24 0.427 A:P00766:0.427
SO4
SO4
SO4
HOH
3.600
7.122
3.529
2.867
CA
O
CA
O
O2
O2
O1
O
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 GLY A:44 A:59 41.0 0.547 55.7 63.4 41.0 0.547 0.0
2jet 2 P07338 89.84 6e-83 X-RAY
2007-09-18 GLY B:41 B:59 39.0 0.52 67.3 50.4 39.0 0.52 0.0 HOH
4.173
CA
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 GLY B:44 B:59 50.0 0.667 58.6 44.1 50.0 0.667 0.0 HOH
3.207
N
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 GLY B:44 B:59 51.0 0.68 59.6 41.7 51.0 0.68 0.0 0FG
HOH
8.451
3.311
N
N
CE2
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 GLY B:44 B:59 50.0 0.667 65.2 46.6 50.0 0.667 0.0 HOH
3.252
O
O
GLY F:44 G:59 51.0 0.68 52.4 49.4 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 GLY B:44 B:59 48.0 0.64 70.3 43.7 48.0 0.64 0.0 HOH
3.083
O
O
GLY F:44 G:59 50.0 0.667 64.7 39.8 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 GLY B:44 F:59 50.0 0.667 55.1 48.1 42.0 0.56 0.107 D:P68390:0.107
HOH
2.330
O
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 GLY B:44 B:59 53.0 0.707 62.7 37.4 9.0 0.12 0.587 B:P00766:0.587
HOH
3.229
O
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 GLY B:44 B:59 53.0 0.707 51.0 39.3 53.0 0.707 0.0 APF
HOH
8.106
2.920
N
O
F12
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 GLY B:44 B:59 52.0 0.693 54.7 42.1 52.0 0.693 0.0 FAF
HOH
8.319
3.260
N
N
CDL
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 GLY B:44 F:59 52.0 0.693 61.2 46.7 6.0 0.08 0.613 B:P00766:0.613
HOH
3.056
N
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 GLY B:44 F:59 51.0 0.68 70.0 41.8 10.0 0.133 0.547 B:P00766:0.547
IPA
IPA
IPA
HOH
8.518
3.435
2.938
3.397
N
CA
O
N
C1
C2
O2
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 GLY B:44 F:59 50.0 0.667 66.6 35.1 5.0 0.067 0.6 B:P00766:0.6
HOH
3.033
O
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 GLY B:44 F:59 49.0 0.653 53.2 54.1 4.0 0.053 0.6 B:P00766:0.6
HEX
HEX
HOH
4.593
3.477
3.191
CA
CA
O
C6
C6
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 GLY B:44 F:59 54.0 0.72 54.1 44.9 54.0 0.72 0.0 ISP
HOH
8.421
3.098
N
CA
O2P
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 GLY B:44 B:59 52.0 0.693 65.4 40.0 44.0 0.587 0.106 D:P68390:0.107
HOH
3.081
N
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 GLY B:44 B:59 38.0 0.507 68.3 37.8 37.0 0.493 0.014 D:P00974:0.013
SO4
HOH
6.969
3.286
CA
N
O4
O
GLY F:44 F:59 47.0 0.627 60.2 50.1 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 GLY B:44 B:59 50.0 0.667 69.6 32.4 50.0 0.667 0.0 HOH
2.897
O
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLY B:44 B:59 53.0 0.707 60.1 39.7 53.0 0.707 0.0 V36
HOH
8.504
3.347
N
C
O3B
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 GLY B:44 C:59 48.0 0.64 63.5 36.0 17.0 0.227 0.413 F:P00766:0.413
SO4
HOH
5.638
2.882
CA
O
O2
O
GLY E:44 D:59 52.0 0.693 62.3 38.8 11.0 0.147 0.546 B:P00766:0.293
C:P00766:0.387
HOH
2.893
O
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 GLY B:44 B:59 54.0 0.72 54.2 46.8 16.0 0.213 0.507 E:P00766:0.12
F:P00766:0.453
HOH
5.050
N
O
GLY E:44 F:59 54.0 0.72 54.2 46.8 14.0 0.187 0.533 B:P00766:0.16
C:P00766:0.467
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 GLY B:44 F:59 50.0 0.667 64.4 41.5 7.0 0.093 0.574 B:P00766:0.573
HOH
3.222
O
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 GLY B:44 B:59 51.0 0.68 57.6 48.3 10.0 0.133 0.547 B:P00766:0.547
HOH
3.091
N
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 GLY B:44 B:59 51.0 0.68 57.1 53.3 8.0 0.107 0.573 B:P00766:0.573
HIN
HOH
6.716
3.259
N
O
C1
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 GLY B:44 B:59 52.0 0.693 63.0 29.9 52.0 0.693 0.0 BVA
HOH
9.093
3.190
N
C
O11
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLY B:44 B:59 55.0 0.733 56.4 44.5 55.0 0.733 0.0 V35
HOH
7.795
3.213
N
C
O1B
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 GLY B:44 B:59 39.0 0.52 42.7 59.5 39.0 0.52 0.0 HOH
3.290
N
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLY B:44 B:59 44.0 0.587 82.9 48.3 4.0 0.053 0.534 B:P00766:0.533
OAC
HOH
7.606
2.748
N
O
O
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 GLY B:44 F:59 53.0 0.707 63.4 38.4 12.0 0.16 0.547 B:P00766:0.547
HOH
3.198
N
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 GLY D:44 D:59 43.0 0.573 71.3 36.8 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLY B:44 B:59 53.0 0.707 60.2 40.4 53.0 0.707 0.0 SRB
HOH
7.957
3.215
N
C
O1B
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 GLY B:44 B:59 50.0 0.667 58.4 38.5 15.0 0.2 0.467 E:P00766:0.08
F:P00766:0.427
HOH
3.329
N
O
GLY E:44 F:59 54.0 0.72 51.5 43.1 17.0 0.227 0.493 B:P00766:0.107
C:P00766:0.453
HOH
3.375
N
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLY B:44 F:59 53.0 0.707 57.1 44.1 7.0 0.093 0.614 B:P00766:0.613
DMC
HOH
7.122
2.645
N
N
O
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLY B:44 B:59 52.0 0.693 63.8 40.5 52.0 0.693 0.0 SRD
HOH
7.423
3.241
N
C
O1B
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 GLY B:44 B:59 52.0 0.693 60.0 36.2 23.0 0.307 0.386 F:P00766:0.387
HOH
3.226
N
O
GLY E:44 F:59 51.0 0.68 52.4 36.8 9.0 0.12 0.56 B:P00766:0.293
C:P00766:0.427
HOH
2.934
O
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLY B:44 F:59 51.0 0.68 77.3 38.7 8.0 0.107 0.573 B:P00766:0.573
HOH
2.903
O
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 50.0 0.667 67.2 35.5 50.0 0.667 0.0 IOD
HOH
7.285
3.306
O
N
I
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 50.0 0.667 65.7 32.8 50.0 0.667 0.0 IOD
HOH
7.112
3.218
O
C
I
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 51.0 0.68 66.3 35.7 51.0 0.68 0.0 IOD
HOH
7.235
3.318
O
N
I
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 50.0 0.667 65.5 34.2 50.0 0.667 0.0 IOD
HOH
7.030
3.259
O
C
I
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 50.0 0.667 66.6 35.9 50.0 0.667 0.0 IOD
HOH
7.279
3.319
O
N
I
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 51.0 0.68 64.4 34.8 51.0 0.68 0.0 IOD
HOH
7.061
3.219
O
C
I
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 50.0 0.667 67.0 35.4 50.0 0.667 0.0 IOD
HOH
7.294
3.311
O
N
I
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 51.0 0.68 63.5 34.0 51.0 0.68 0.0 IOD
HOH
7.018
3.215
O
C
I
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 51.0 0.68 65.6 37.2 51.0 0.68 0.0 IOD
HOH
7.309
3.308
O
N
I
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 54.0 0.72 67.9 29.1 54.0 0.72 0.0 IOD
IOD
HOH
7.060
8.138
3.173
O
O
C
I
I
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 51.0 0.68 67.5 34.7 51.0 0.68 0.0 IOD
HOH
7.292
3.310
O
N
I
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLY B:44 B:59 54.0 0.72 69.3 28.0 54.0 0.72 0.0 IOD
IOD
HOH
6.942
8.175
3.178
O
O
C
I
I
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 GLY B:44 B:59 49.0 0.653 45.1 37.6 21.0 0.28 0.373 F:P00766:0.373
PBA
HOH
9.262
3.247
N
N
O2
O
GLY E:44 F:59 51.0 0.68 53.3 46.8 8.0 0.107 0.573 B:P00766:0.373
C:P00766:0.413
PBA
HOH
9.797
3.362
N
C
O1
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 GLY B:44 B:59 50.0 0.667 62.1 37.8 50.0 0.667 0.0 SO4
SO4
HOH
3.433
6.270
2.711
CA
O
O
O4
O4
O
GLY E:44 E:59 51.0 0.68 62.0 37.9 NA NA NA
GLY H:44 H:59 47.0 0.627 62.1 37.7 NA NA NA
GLY K:44 K:59 51.0 0.68 62.5 37.6 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLY B:44 F:59 52.0 0.693 47.3 46.2 2.0 0.027 0.666 B:P00766:0.667
APF
HOH
7.962
2.732
N
O
F11
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLY B:44 F:59 51.0 0.68 56.3 46.2 51.0 0.68 0.0 LPF
HOH
7.923
3.056
N
O
F12
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 GLY B:44 B:59 51.0 0.68 60.9 39.1 18.0 0.24 0.44 D:Q6VEQ7:0.44
HOH
2.808
O
O
GLY F:44 b:59 51.0 0.68 61.3 41.4 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 GLY B:44 F:59 48.0 0.64 59.9 39.3 48.0 0.64 0.0 HOH
2.812
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 GLY A:77 A:77 42.0 0.56 64.5 30.1
af-p17538-f1 1 P17538 95.82 0.0 GLY A:77 A:77 42.0 0.56 67.2 22.2