Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75256870 . A C CCDS32490.1:NM_001906.4:c.160Aaa>Caa_NP_001897.4:p.54K>Q Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
1993-10-31 LYS A:36 E:36 172.0 0.86 T -58.0 -26.4 172.0 0.86 0.0 HOH
2.439
O
O
1cgi 1 P00766 81.63 3e-148 X-RAY
1993-10-31 LYS A:36 E:36 182.0 0.91 T -77.8 -23.0 182.0 0.91 0.0 HOH
7.660
O
O
1cgj 1 P00766 81.63 3e-148 X-RAY
1993-10-31 LYS A:36 E:36 188.0 0.94 S -82.9 -35.1 188.0 0.94 0.0 HOH
7.864
N
O
1chg 1 P00766 81.63 3e-148 X-RAY
1976-11-22 LYS A:36 A:36 171.0 0.855 T -57.6 -31.0 171.0 0.855 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
2000-05-17 LYS A:36 A:36 167.0 0.835 S -56.9 -69.7 167.0 0.835 0.0 HOH
6.596
N
O
1gcd 1 P00766 81.63 3e-148 X-RAY
1994-06-22 LYS A:36 A:36 184.0 0.92 T -51.3 -33.4 148.0 0.74 0.18 A:P00766:0.18
SO4
HOH
2.737
2.680
NZ
NZ
O3
O
1gl0 1 P00766 81.63 3e-148 X-RAY
2001-11-28 LYS A:36 E:36 173.0 0.865 T -47.0 -42.6 173.0 0.865 0.0 HOH
4.978
O
O
1gl1 1 P00766 81.63 3e-148 X-RAY
2001-11-28 LYS A:36 A:36 174.0 0.87 T -53.5 -34.4 174.0 0.87 0.0 HOH
5.424
O
O
LYS B:36 B:36 173.0 0.865 T -59.9 -35.4 NA NA NA
LYS C:36 C:36 173.0 0.865 T -59.9 -39.2 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
2001-12-05 LYS A:36 1:36 172.0 0.86 T -61.6 -17.9 172.0 0.86 0.0 HOH
2.721
O
O
1oxg 1 P00766 81.63 3e-148 X-RAY
2004-05-18 LYS A:36 A:36 155.0 0.775 T -57.0 -37.9 155.0 0.775 0.0 HOH
2.830
CD
O
1p2m 1 P00766 81.63 3e-148 X-RAY
2004-04-20 LYS A:36 A:36 166.0 0.83 T -56.0 -20.9 166.0 0.83 0.0 HOH
2.793
N
O
LYS C:36 C:36 172.0 0.86 T -58.7 -16.9 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
2004-04-20 LYS A:36 A:36 167.0 0.835 T -57.9 -17.4 167.0 0.835 0.0 HOH
2.735
N
O
LYS C:36 C:36 187.0 0.935 T -57.8 -17.6 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
2004-04-20 LYS A:36 A:36 164.0 0.82 T -55.9 -17.4 164.0 0.82 0.0 HOH
3.557
O
O
LYS C:36 C:36 170.0 0.85 T -58.5 -15.0 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
2004-04-20 LYS A:36 A:36 187.0 0.935 T -56.3 -19.3 187.0 0.935 0.0 TRS
HOH
5.517
2.824
N
N
O3
O
LYS C:36 C:36 168.0 0.84 T -57.1 -17.2 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
2005-03-08 LYS A:36 A:36 187.0 0.935 T -55.3 -20.6 187.0 0.935 0.0 HOH
2.760
N
O
LYS C:36 C:36 188.0 0.94 T -58.8 -15.9 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
2005-03-08 LYS A:36 A:36 188.0 0.94 T -60.6 -15.7 188.0 0.94 0.0 HOH
2.925
N
O
LYS C:36 C:36 185.0 0.925 T -60.2 -14.4 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
2005-03-08 LYS A:36 A:36 184.0 0.92 T -55.4 -18.5 184.0 0.92 0.0 HOH
2.922
N
O
LYS C:36 C:36 181.0 0.905 T -57.2 -16.0 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
2005-03-08 LYS A:36 A:36 184.0 0.92 T -58.1 -18.7 184.0 0.92 0.0 HOH
2.777
N
O
LYS C:36 C:36 188.0 0.94 T -59.6 -14.9 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
2005-03-08 LYS A:36 A:36 166.0 0.83 T -56.7 -19.3 166.0 0.83 0.0 HOH
2.854
N
O
LYS C:36 C:36 189.0 0.945 T -57.0 -15.6 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
1987-04-16 LYS A:36 A:36 171.0 0.855 T -41.9 -46.2 171.0 0.855 0.0 HOH
3.315
NZ
O
LYS B:36 B:36 185.0 0.925 T -86.2 -17.7 185.0 0.925 0.0 HOH
7.290
N
O
2y6t 1 P00766 81.63 3e-148 X-RAY
2011-04-20 LYS A:36 A:36 180.0 0.9 T -38.6 -49.2 180.0 0.9 0.0
LYS B:36 B:36 168.0 0.84 T -59.8 -20.6 168.0 0.84 0.0
LYS C:36 C:36 181.0 0.905 S -57.6 -43.9 NA NA NA
LYS D:36 D:36 162.0 0.81 T -57.1 -29.7 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
2012-08-01 LYS A:36 A:36 172.0 0.86 T -73.1 -10.4 172.0 0.86 0.0 HOH
3.138
N
O
LYS C:36 B:36 159.0 0.795 T -72.1 -12.1 NA NA NA
LYS E:36 C:36 172.0 0.86 T -63.9 -16.8 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
2014-07-23 LYS A:36 A:36 180.0 0.9 T -59.6 -17.8 180.0 0.9 0.0 HOH
2.691
N
O
LYS B:36 B:36 159.0 0.795 T -57.0 -19.5 NA NA NA
LYS C:36 C:36 94.0 NA T -67.1 7.1 NA NA NA
LYS D:36 D:36 177.0 0.885 T -66.8 -22.2 144.0 0.72 0.165 A:P00766:0.165
HOH
3.627
CE
O
5j4q 1 P00766 81.63 3e-148 X-RAY
2017-04-12 LYS A:36 A:36 173.0 0.865 T -48.7 -40.4 173.0 0.865 0.0 HOH
3.140
N
O
5j4s 1 P00766 81.63 3e-148 X-RAY
2017-04-12 LYS A:36 A:36 176.0 0.88 T -61.2 -24.7 176.0 0.88 0.0 HOH
2.472
H
O
7kty 1 P00766 81.63 3e-148 X-RAY
2021-03-10 LYS A:36 A:36 162.0 0.81 T -61.8 -15.3 127.0 0.635 0.175 A:P00766:0.175
SO4
SO4
HOH
9.145
6.291
3.794
NZ
NZ
O
O3
O4
O
7ktz 1 P00766 81.63 3e-148 X-RAY
2021-03-10 LYS A:36 A:36 142.0 0.71 T -47.3 -37.4 142.0 0.71 0.0 SO4
SO4
HOH
8.171
9.029
2.950
NZ
NZ
N
O3
O4
O
7ku0 1 P00766 81.63 3e-148 X-RAY
2021-03-10 LYS A:36 A:36 167.0 0.835 T -62.5 -12.5 126.0 0.63 0.205 A:P00766:0.205
SO4
SO4
HOH
9.102
5.627
2.349
NZ
NZ
NZ
O3
O2
O
7ku1 1 P00766 81.63 3e-148 X-RAY
2021-03-10 LYS A:36 A:36 170.0 0.85 T -48.2 -24.6 170.0 0.85 0.0
7ku2 1 P00766 81.63 3e-148 X-RAY
2021-03-10 LYS A:36 A:36 166.0 0.83 T -47.5 -28.1 166.0 0.83 0.0 HOH
4.129
CG
O
7ku3 1 P00766 81.63 3e-148 X-RAY
2021-03-10 LYS A:36 A:36 166.0 0.83 T -62.5 -13.3 125.0 0.625 0.205 A:P00766:0.205
SO4
SO4
HOH
9.094
5.685
2.605
NZ
NZ
O
O3
O2
O
1dlk 2 P00766 80.87 2e-137 X-RAY
2000-05-03 LYS B:21 B:36 163.0 0.815 T -67.4 -7.7 153.0 0.765 0.05 D:P00766:0.05
HOH
2.617
NZ
O
LYS D:21 D:36 160.0 0.8 T -78.8 0.1 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 LYS A:21 A:36 180.0 0.9 T -54.3 -5.9 180.0 0.9 0.0
2jet 2 P07338 89.84 5e-83 X-RAY
2007-09-18 LYS B:18 B:36 149.0 0.745 T -54.7 -34.1 149.0 0.745 0.0 HOH
2.721
N
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 LYS B:21 B:36 177.0 0.885 T -60.1 -23.0 177.0 0.885 0.0 HOH
2.631
O
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 LYS B:21 B:36 175.0 0.875 T -59.3 -20.6 175.0 0.875 0.0 HOH
2.919
N
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 LYS B:21 B:36 175.0 0.875 T -49.3 -48.8 175.0 0.875 0.0 HOH
4.293
O
O
LYS F:21 G:36 163.0 0.815 T -53.0 -26.9 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 LYS B:21 B:36 170.0 0.85 T -50.8 -40.1 170.0 0.85 0.0 HOH
4.043
O
O
LYS F:21 G:36 163.0 0.815 T -60.8 -8.0 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 LYS B:21 F:36 116.0 0.58 T -54.2 -29.5 116.0 0.58 0.0 HOH
3.017
N
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 LYS B:21 B:36 178.0 0.89 T -58.4 -24.1 155.0 0.775 0.115 B:P00766:0.115
SO4
HOH
2.452
2.780
NZ
O
O4
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 LYS B:21 B:36 172.0 0.86 T -59.2 -15.2 172.0 0.86 0.0 APL
HOH
7.675
2.885
O
N
CN2
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 LYS B:21 B:36 172.0 0.86 T -62.8 -17.5 172.0 0.86 0.0 HOH
2.642
O
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 LYS B:21 F:36 176.0 0.88 T -66.1 2.7 152.0 0.76 0.12 B:P00766:0.12
SO4
HOH
3.246
3.445
CE
NZ
O4
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 LYS B:21 F:36 170.0 0.85 T -78.5 9.6 147.0 0.735 0.115 B:P00766:0.115
HOH
2.779
NZ
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 LYS B:21 F:36 169.0 0.845 T -64.5 -13.9 144.0 0.72 0.125 B:P00766:0.125
HOH
2.965
N
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 LYS B:21 F:36 163.0 0.815 T -65.6 -14.3 148.0 0.74 0.075 B:P00766:0.075
HOH
3.172
N
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 LYS B:21 F:36 179.0 0.895 T -57.0 -28.1 179.0 0.895 0.0 HOH
3.203
O
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 LYS B:21 B:36 131.0 0.655 T -62.6 -43.3 131.0 0.655 0.0 HOH
3.616
CG
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 LYS B:21 B:36 178.0 0.89 T -54.4 -49.2 178.0 0.89 0.0 HOH
7.986
CG
O
LYS F:21 F:36 185.0 0.925 T -27.6 -71.2 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 LYS B:21 B:36 114.0 0.57 T -72.1 -8.4 114.0 0.57 0.0 HOH
2.727
CG
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 LYS B:21 B:36 174.0 0.87 T -66.2 -18.1 174.0 0.87 0.0 HOH
2.925
NZ
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 LYS B:21 C:36 175.0 0.875 T -66.4 -16.4 149.0 0.745 0.13 F:P00766:0.13
HOH
3.049
N
O
LYS E:21 D:36 171.0 0.855 T -67.2 -15.8 136.0 0.68 0.175 C:P00766:0.175
HOH
2.828
NZ
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 LYS B:21 B:36 147.0 0.735 S -120.4 1.8 147.0 0.735 0.0 HOH
2.811
N
O
LYS E:21 F:36 147.0 0.735 S -120.4 1.8 147.0 0.735 0.0 HOH
7.016
C
O
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 LYS B:21 F:36 177.0 0.885 T -62.9 -15.8 145.0 0.725 0.16 B:P00766:0.16
HOH
2.445
NZ
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 LYS B:21 B:36 178.0 0.89 T -58.2 -23.3 158.0 0.79 0.1 B:P00766:0.1
SO4
SO4
HOH
9.613
2.868
2.965
O
CE
O
O4
O4
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 LYS B:21 B:36 171.0 0.855 T -65.9 -19.4 134.0 0.67 0.185 B:P00766:0.185
HOH
2.486
NZ
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 LYS B:21 B:36 173.0 0.865 T -70.0 -18.0 173.0 0.865 0.0 HOH
2.812
O
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 LYS B:21 B:36 172.0 0.86 T -61.5 -15.7 172.0 0.86 0.0 HOH
2.708
NZ
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 LYS B:21 B:36 170.0 0.85 T -61.2 -25.5 170.0 0.85 0.0 HOH
8.525
N
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 LYS B:21 B:36 185.0 0.925 T -45.8 -21.2 153.0 0.765 0.16 B:P00766:0.16
HOH
3.576
N
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 LYS B:21 F:36 171.0 0.855 T -65.4 -25.3 150.0 0.75 0.105 B:P00766:0.105
SO4
HOH
2.460
2.682
NZ
O
O4
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 LYS D:21 D:36 179.0 0.895 T -66.4 -11.2 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 LYS B:21 B:36 176.0 0.88 T -61.2 -17.7 176.0 0.88 0.0 HOH
2.824
NZ
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 LYS B:21 B:36 161.0 0.805 T -68.1 -25.2 160.0 0.8 0.005 F:P00766:0.005
HOH
8.065
CG
O
LYS E:21 F:36 143.0 0.715 T -84.7 4.3 143.0 0.715 0.0 HOH
6.237
CE
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 LYS B:21 F:36 179.0 0.895 S -79.7 -10.0 147.0 0.735 0.16 B:P00766:0.16
HOH
3.053
N
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 LYS B:21 B:36 175.0 0.875 T -60.3 -8.5 175.0 0.875 0.0 HOH
2.888
NZ
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 LYS B:21 B:36 150.0 0.75 S -71.0 -42.1 150.0 0.75 0.0 HOH
3.910
NZ
O
LYS E:21 F:36 107.0 0.535 T -85.3 12.9 107.0 0.535 0.0 HOH
4.467
C
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 LYS B:21 F:36 179.0 0.895 T -53.9 -10.2 149.0 0.745 0.15 B:P00766:0.15
HOH
3.408
NZ
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 180.0 0.9 T -60.9 -27.6 180.0 0.9 0.0 HOH
2.784
O
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 177.0 0.885 T -64.7 -23.5 177.0 0.885 0.0 HOH
2.751
O
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 172.0 0.86 T -66.2 -21.9 172.0 0.86 0.0 HOH
2.738
O
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 179.0 0.895 T -67.8 -18.1 179.0 0.895 0.0 HOH
2.669
O
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 174.0 0.87 T -68.6 -16.3 174.0 0.87 0.0 HOH
3.004
N
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 177.0 0.885 T -49.9 -37.5 177.0 0.885 0.0 HOH
2.973
N
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 174.0 0.87 T -65.6 -19.6 174.0 0.87 0.0 HOH
2.823
O
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 180.0 0.9 T -52.2 -36.9 180.0 0.9 0.0 HOH
2.998
N
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 168.0 0.84 T -67.5 -16.7 168.0 0.84 0.0 HOH
2.782
O
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 176.0 0.88 T -59.9 -27.6 176.0 0.88 0.0 HOH
2.787
NZ
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 174.0 0.87 T -65.0 -20.2 174.0 0.87 0.0 HOH
2.728
O
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 LYS B:21 B:36 173.0 0.865 T -57.4 -31.9 173.0 0.865 0.0 HOH
2.619
O
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 LYS B:21 B:36 148.0 0.74 S -61.7 -29.1 148.0 0.74 0.0 HOH
3.909
N
O
LYS E:21 F:36 116.0 0.58 T -71.0 -27.5 115.0 0.575 0.005 C:P00766:0.005
HOH
4.582
C
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 LYS B:21 B:36 96.0 NA T -59.4 -22.9 96.0 NA NA SO4
HOH
4.860
3.360
CG
CG
O3
O
LYS E:21 E:36 162.0 0.81 T -58.4 -23.7 NA NA NA
LYS H:21 H:36 95.0 NA T -58.5 -23.8 NA NA NA
LYS K:21 K:36 167.0 0.835 T -59.0 -23.5 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 LYS B:21 F:36 178.0 0.89 T -59.6 -17.1 157.0 0.785 0.105 B:P00766:0.105
HOH
2.897
CE
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 LYS B:21 F:36 179.0 0.895 T -49.0 -31.2 179.0 0.895 0.0 HOH
7.725
N
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 LYS B:21 B:36 172.0 0.86 T -65.9 -15.4 172.0 0.86 0.0 HOH
2.875
O
O
LYS F:21 b:36 169.0 0.845 T -64.6 -16.8 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 LYS B:21 F:36 178.0 0.89 T -57.9 -32.5 178.0 0.89 0.0 HOH
3.042
NZ
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 LYS A:54 A:54 181.0 0.905 T -59.4 -7.5
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 LYS A:54 A:54 174.0 0.87 T -61.0 -15.5