Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75257046 . G A CCDS32490.1:NM_001906.4:c.244Gac>Aac_NP_001897.4:p.82D>N Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
1993-10-31 ASP A:64 E:64 18.0 0.12 S -86.4 164.8 18.0 0.12 0.0 HOH
2.726
O
O
1cgi 1 P00766 81.63 3e-148 X-RAY
1993-10-31 ASP A:64 E:64 18.0 0.12 S -83.8 163.2 16.0 0.107 0.013 B:P00995:0.013
1cgj 1 P00766 81.63 3e-148 X-RAY
1993-10-31 ASP A:64 E:64 18.0 0.12 S -90.8 158.2 14.0 0.093 0.027 B:P00995:0.027
HOH
6.989
OD1
O
1chg 1 P00766 81.63 3e-148 X-RAY
1976-11-22 ASP A:64 A:64 15.0 0.1 -107.5 151.7 15.0 0.1 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
2000-05-17 ASP A:64 A:64 16.0 0.107 S -74.0 175.4 16.0 0.107 0.0 HOH
2.839
OD1
O
1gcd 1 P00766 81.63 3e-148 X-RAY
1994-06-22 ASP A:64 A:64 20.0 0.133 S -90.3 166.3 5.0 0.033 0.1 A:P00766:0.1
SO4
HOH
9.215
2.680
OD1
OD1
O3
O
1gl0 1 P00766 81.63 3e-148 X-RAY
2001-11-28 ASP A:64 E:64 22.0 0.147 S -105.5 167.6 22.0 0.147 0.0 HOH
2.567
O
O
1gl1 1 P00766 81.63 3e-148 X-RAY
2001-11-28 ASP A:64 A:64 20.0 0.133 S -88.6 169.3 20.0 0.133 0.0 HOH
2.543
O
O
ASP B:64 B:64 17.0 0.113 S -90.8 166.1 NA NA NA
ASP C:64 C:64 20.0 0.133 S -102.4 165.7 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
2001-12-05 ASP A:64 1:64 15.0 0.1 S -82.2 164.0 15.0 0.1 0.0 HOH
2.627
O
O
1oxg 1 P00766 81.63 3e-148 X-RAY
2004-05-18 ASP A:64 A:64 15.0 0.1 S -92.2 164.4 15.0 0.1 0.0 SO4
HOH
6.807
2.688
N
O
O2
O
1p2m 1 P00766 81.63 3e-148 X-RAY
2004-04-20 ASP A:64 A:64 21.0 0.14 S -85.3 167.7 21.0 0.14 0.0 HOH
2.624
O
O
ASP C:64 C:64 20.0 0.133 S -85.6 167.1 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
2004-04-20 ASP A:64 A:64 21.0 0.14 S -85.3 166.4 21.0 0.14 0.0 HOH
2.656
O
O
ASP C:64 C:64 21.0 0.14 S -84.4 167.3 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
2004-04-20 ASP A:64 A:64 20.0 0.133 S -83.2 170.9 20.0 0.133 0.0 HOH
2.654
O
O
ASP C:64 C:64 22.0 0.147 S -86.4 166.4 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
2004-04-20 ASP A:64 A:64 20.0 0.133 S -83.3 167.3 20.0 0.133 0.0 TRS
HOH
2.634
2.642
OD1
O
O3
O
ASP C:64 C:64 21.0 0.14 S -85.7 167.1 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
2005-03-08 ASP A:64 A:64 20.0 0.133 S -85.0 167.1 20.0 0.133 0.0 HOH
2.619
OD1
O
ASP C:64 C:64 21.0 0.14 S -89.3 166.5 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
2005-03-08 ASP A:64 A:64 21.0 0.14 S -84.7 167.9 21.0 0.14 0.0 HOH
2.622
O
O
ASP C:64 C:64 20.0 0.133 S -85.8 166.6 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
2005-03-08 ASP A:64 A:64 20.0 0.133 S -81.4 170.3 20.0 0.133 0.0 HOH
2.629
O
O
ASP C:64 C:64 20.0 0.133 S -84.8 166.5 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
2005-03-08 ASP A:64 A:64 21.0 0.14 S -82.7 168.4 21.0 0.14 0.0 HOH
2.657
OD1
O
ASP C:64 C:64 20.0 0.133 S -87.6 165.9 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
2005-03-08 ASP A:64 A:64 20.0 0.133 S -83.7 169.0 20.0 0.133 0.0 HOH
2.608
O
O
ASP C:64 C:64 22.0 0.147 S -85.6 167.9 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
1987-04-16 ASP A:64 A:64 16.0 0.107 S -61.3 155.0 16.0 0.107 0.0 HOH
2.959
O
O
ASP B:64 B:64 19.0 0.127 -81.9 171.3 19.0 0.127 0.0 HOH
2.675
O
O
2y6t 1 P00766 81.63 3e-148 X-RAY
2011-04-20 ASP A:64 A:64 15.0 0.1 -83.6 159.2 15.0 0.1 0.0 HOH
9.765
OD2
O
ASP B:64 B:64 16.0 0.107 S -75.6 169.9 16.0 0.107 0.0
ASP C:64 C:64 15.0 0.1 -96.4 165.7 NA NA NA
ASP D:64 D:64 15.0 0.1 -80.1 169.3 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
2012-08-01 ASP A:64 A:64 19.0 0.127 S -80.7 167.4 19.0 0.127 0.0 HOH
2.638
OD2
O
ASP C:64 B:64 15.0 0.1 S -83.8 160.7 NA NA NA
ASP E:64 C:64 12.0 0.08 S -86.9 167.2 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
2014-07-23 ASP A:64 A:64 20.0 0.133 S -89.8 174.8 20.0 0.133 0.0 HOH
2.681
OD2
O
ASP B:64 B:64 20.0 0.133 S -74.8 164.0 NA NA NA
ASP C:64 C:64 23.0 0.153 S -79.5 178.8 NA NA NA
ASP D:64 D:64 23.0 0.153 S -87.7 167.7 10.0 0.067 0.086 A:P00766:0.087
HOH
2.660
O
O
5j4q 1 P00766 81.63 3e-148 X-RAY
2017-04-12 ASP A:64 A:64 17.0 0.113 S -89.5 163.2 17.0 0.113 0.0 HOH
2.707
O
O
5j4s 1 P00766 81.63 3e-148 X-RAY
2017-04-12 ASP A:64 A:64 17.0 0.113 S -84.0 160.1 17.0 0.113 0.0 HOH
2.612
O
O
7kty 1 P00766 81.63 3e-148 X-RAY
2021-03-10 ASP A:64 A:64 18.0 0.12 S -86.3 166.6 18.0 0.12 0.0 SO4
SO4
SO4
HOH
8.329
6.549
7.581
2.725
OD1
N
OD1
O
O4
O3
O1
O
7ktz 1 P00766 81.63 3e-148 X-RAY
2021-03-10 ASP A:64 A:64 17.0 0.113 S -82.3 168.5 16.0 0.107 0.006 A:P00766:0.007
SO4
SO4
SO4
HOH
7.285
6.327
8.168
2.607
OD2
N
OD2
O
O4
O3
O1
O
7ku0 1 P00766 81.63 3e-148 X-RAY
2021-03-10 ASP A:64 A:64 16.0 0.107 S -79.0 168.8 15.0 0.1 0.007 A:P00766:0.007
SO4
SO4
SO4
HOH
8.168
6.299
7.158
2.565
OD2
N
OD2
O
O4
O3
O1
O
7ku1 1 P00766 81.63 3e-148 X-RAY
2021-03-10 ASP A:64 A:64 12.0 0.08 S -77.6 168.2 12.0 0.08 0.0
7ku2 1 P00766 81.63 3e-148 X-RAY
2021-03-10 ASP A:64 A:64 14.0 0.093 S -87.3 162.0 14.0 0.093 0.0 HOH
4.328
N
O
7ku3 1 P00766 81.63 3e-148 X-RAY
2021-03-10 ASP A:64 A:64 18.0 0.12 S -76.9 167.6 16.0 0.107 0.013 A:P00766:0.013
SO4
SO4
SO4
HOH
7.995
6.472
7.396
2.579
OD2
N
OD2
O
O4
O3
O1
O
1dlk 2 P00766 80.87 2e-137 X-RAY
2000-05-03 ASP B:49 B:64 20.0 0.133 S -78.2 170.7 20.0 0.133 0.0 HOH
2.421
O
O
ASP D:49 D:64 21.0 0.14 S -79.7 162.9 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 ASP A:49 A:64 13.0 0.087 -100.5 149.5 13.0 0.087 0.0
2jet 2 P07338 89.84 5e-83 X-RAY
2007-09-18 ASP B:46 B:64 1.0 0.007 -73.8 158.2 1.0 0.007 0.0 HOH
2.687
OD1
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 ASP B:49 B:64 17.0 0.113 S -81.0 161.4 17.0 0.113 0.0 HOH
2.693
O
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 ASP B:49 B:64 20.0 0.133 S -84.3 165.5 20.0 0.133 0.0 HOH
2.617
O
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 ASP B:49 B:64 15.0 0.1 S -81.1 157.5 15.0 0.1 0.0 HOH
2.756
O
O
ASP F:49 G:64 15.0 0.1 S -90.9 171.0 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 ASP B:49 B:64 19.0 0.127 S -85.4 163.3 19.0 0.127 0.0 HOH
2.636
O
O
ASP F:49 G:64 18.0 0.12 S -80.6 178.3 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 ASP B:49 F:64 16.0 0.107 -84.3 165.2 10.0 0.067 0.04 D:P68390:0.04
HOH
2.674
O
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 ASP B:49 B:64 18.0 0.12 S -86.1 162.3 5.0 0.033 0.087 B:P00766:0.087
SO4
HOH
9.080
2.521
OD2
O
O4
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 ASP B:49 B:64 15.0 0.1 S -89.1 166.3 15.0 0.1 0.0 HOH
2.663
O
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 ASP B:49 B:64 17.0 0.113 S -83.9 164.5 17.0 0.113 0.0 HOH
2.653
O
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 ASP B:49 F:64 21.0 0.14 S -85.8 179.5 10.0 0.067 0.073 B:P00766:0.073
SO4
HOH
9.442
4.694
OD1
OD1
O1
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 ASP B:49 F:64 18.0 0.12 S -83.3 158.2 5.0 0.033 0.087 B:P00766:0.087
IPA
IPA
HOH
7.321
6.177
2.446
OD2
OD2
O
C3
O2
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 ASP B:49 F:64 15.0 0.1 S -84.1 158.1 3.0 0.02 0.08 B:P00766:0.08
HOH
2.805
O
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 ASP B:49 F:64 14.0 0.093 S -69.1 159.8 2.0 0.013 0.08 B:P00766:0.08
HEX
HOH
7.663
2.901
OD2
O
C6
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 ASP B:49 F:64 21.0 0.14 S -84.4 159.8 21.0 0.14 0.0 HOH
2.443
O
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 ASP B:49 B:64 20.0 0.133 S -87.8 167.7 15.0 0.1 0.033 D:P68390:0.033
HOH
2.802
OD1
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 ASP B:49 B:64 24.0 0.16 S -92.0 175.8 24.0 0.16 0.0 HOH
2.677
O
O
ASP F:49 F:64 18.0 0.12 S -90.7 174.2 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 ASP B:49 B:64 15.0 0.1 -90.8 164.0 15.0 0.1 0.0 HOH
2.750
OD1
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ASP B:49 B:64 18.0 0.12 S -87.3 159.2 18.0 0.12 0.0 HOH
6.073
C
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 ASP B:49 C:64 16.0 0.107 S -82.2 161.2 5.0 0.033 0.074 F:P00766:0.073
HOH
2.633
OD2
O
ASP E:49 D:64 14.0 0.093 S -86.0 159.6 3.0 0.02 0.073 C:P00766:0.073
HOH
2.630
OD2
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 ASP B:49 B:64 21.0 0.14 S -81.8 165.0 9.0 0.06 0.08 F:P00766:0.08
HOH
2.818
O
O
ASP E:49 F:64 21.0 0.14 S -81.8 165.0 9.0 0.06 0.08 C:P00766:0.08
HOH
8.796
OD2
O
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 ASP B:49 F:64 18.0 0.12 S -83.3 161.7 6.0 0.04 0.08 B:P00766:0.08
HOH
2.865
O
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 ASP B:49 B:64 11.0 0.073 S -104.6 164.8 2.0 0.013 0.06 B:P00766:0.06
SO4
HOH
9.115
2.381
OD2
O
O4
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 ASP B:49 B:64 19.0 0.127 S -76.5 170.7 6.0 0.04 0.087 B:P00766:0.087
HOH
2.303
O
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 ASP B:49 B:64 19.0 0.127 S -85.2 168.3 19.0 0.127 0.0 HOH
2.658
O
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ASP B:49 B:64 18.0 0.12 S -86.8 158.6 18.0 0.12 0.0 HOH
7.120
OD2
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 ASP B:49 B:64 14.0 0.093 S -80.5 153.6 14.0 0.093 0.0 HOH
2.556
O
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ASP B:49 B:64 20.0 0.133 S -86.3 158.7 7.0 0.047 0.086 B:P00766:0.087
HOH
2.803
OD2
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 ASP B:49 F:64 20.0 0.133 S -85.3 163.9 7.0 0.047 0.086 B:P00766:0.087
SO4
HOH
9.109
2.587
OD2
O
O4
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 ASP D:49 D:64 17.0 0.113 S -88.2 167.0 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ASP B:49 B:64 21.0 0.14 S -84.7 162.4 21.0 0.14 0.0 HOH
6.362
C
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 ASP B:49 B:64 16.0 0.107 S -79.2 161.0 5.0 0.033 0.074 F:P00766:0.073
HOH
2.716
O
O
ASP E:49 F:64 17.0 0.113 S -77.7 162.1 7.0 0.047 0.066 C:P00766:0.067
HOH
2.590
O
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ASP B:49 F:64 18.0 0.12 -90.4 165.2 5.0 0.033 0.087 B:P00766:0.087
HOH
2.993
O
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ASP B:49 B:64 19.0 0.127 S -83.2 155.6 19.0 0.127 0.0 HOH
7.006
OD2
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 ASP B:49 B:64 19.0 0.127 S -69.6 161.5 9.0 0.06 0.067 F:P00766:0.067
HOH
3.183
O
O
ASP E:49 F:64 13.0 0.087 S -89.4 161.2 4.0 0.027 0.06 C:P00766:0.06
HOH
2.459
O
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ASP B:49 F:64 21.0 0.14 S -89.0 154.6 9.0 0.06 0.08 B:P00766:0.08
HOH
3.020
OD2
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 21.0 0.14 S -84.0 167.0 21.0 0.14 0.0 IOD
HOH
7.961
2.663
OD2
O
I
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 19.0 0.127 S -85.2 167.6 19.0 0.127 0.0 IOD
HOH
7.912
2.640
OD2
O
I
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 19.0 0.127 S -85.9 168.7 19.0 0.127 0.0 IOD
HOH
7.888
2.648
OD2
O
I
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 20.0 0.133 S -85.7 168.6 20.0 0.133 0.0 IOD
HOH
7.796
2.665
OD2
O
I
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 17.0 0.113 S -83.0 166.9 17.0 0.113 0.0 IOD
HOH
7.922
2.664
OD2
O
I
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 20.0 0.133 S -85.3 166.2 20.0 0.133 0.0 IOD
HOH
7.773
2.667
OD2
O
I
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 14.0 0.093 S -84.3 167.6 14.0 0.093 0.0 IOD
HOH
7.919
2.654
OD2
O
I
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 20.0 0.133 S -86.9 168.3 20.0 0.133 0.0 IOD
HOH
7.749
2.657
OD2
O
I
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 17.0 0.113 S -82.9 166.9 17.0 0.113 0.0 IOD
HOH
7.851
2.641
OD2
O
I
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 23.0 0.153 S -88.7 167.3 23.0 0.153 0.0 IOD
SO4
HOH
8.276
9.368
2.569
N
O
O
I
O4
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 19.0 0.127 S -84.9 166.7 19.0 0.127 0.0 IOD
HOH
7.895
2.654
OD2
O
I
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ASP B:49 B:64 18.0 0.12 S -85.2 166.5 18.0 0.12 0.0 IOD
IOD
SO4
HOH
7.662
8.396
9.400
2.648
OD2
N
O
OD1
I
I
O4
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 ASP B:49 B:64 18.0 0.12 -74.2 176.4 8.0 0.053 0.067 F:P00766:0.067
HOH
2.800
OD2
O
ASP E:49 F:64 13.0 0.087 -70.5 157.4 4.0 0.027 0.06 C:P00766:0.06
HOH
5.708
O
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 ASP B:49 B:64 15.0 0.1 S -82.1 163.6 15.0 0.1 0.0 SO4
SO4
HOH
7.509
5.204
2.479
OD2
OD1
OD1
O4
O4
O
ASP E:49 E:64 14.0 0.093 S -84.0 160.9 NA NA NA
ASP H:49 H:64 13.0 0.087 S -83.8 161.8 NA NA NA
ASP K:49 K:64 14.0 0.093 S -84.7 161.3 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ASP B:49 F:64 20.0 0.133 S -78.6 157.9 7.0 0.047 0.086 B:P00766:0.087
HOH
2.643
O
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ASP B:49 F:64 22.0 0.147 S -86.1 157.3 22.0 0.147 0.0 HOH
2.339
O
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 ASP B:49 B:64 19.0 0.127 S -77.8 164.3 16.0 0.107 0.02 D:Q6VEQ7:0.02
HOH
2.518
OD2
O
ASP F:49 b:64 19.0 0.127 S -76.8 162.9 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 ASP B:49 F:64 22.0 0.147 S -91.1 165.6 22.0 0.147 0.0 HOH
2.538
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 ASP A:82 A:82 7.0 0.047 S -95.5 160.8
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 ASP A:82 A:82 14.0 0.093 S -87.2 164.6