Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75257100 . G A CCDS32490.1:NM_001906.4:c.298Gtc>Atc_NP_001897.4:p.100V>I Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 LYS A:82 E:82 132.0 0.66 E -104.1 111.6 132.0 0.66 0.0 HOH
 4.230
 CE
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 LYS A:82 E:82 141.0 0.705 E -103.2 91.3 141.0 0.705 0.0 HOH
 4.448
 CD
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 LYS A:82 E:82 145.0 0.725 E -103.8 94.9 145.0 0.725 0.0 HOH
 4.528
 CD
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 LYS A:82 A:82 121.0 0.605 E -105.8 121.9 121.0 0.605 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 LYS A:82 A:82 138.0 0.69 E -104.7 105.8 138.0 0.69 0.0 HOH
 2.981
 NZ
 O
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 LYS A:82 A:82 145.0 0.725 E -96.1 107.4 145.0 0.725 0.0 HOH
 2.655
 O
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 LYS A:82 E:82 148.0 0.74 E -82.5 116.2 148.0 0.74 0.0 HOH
 3.825
 NZ
 O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 LYS A:82 A:82 153.0 0.765 E -96.7 112.5 153.0 0.765 0.0 HOH
 5.098
 CE
 O
LYS B:82 B:82 149.0 0.745 E -98.1 109.2 NA NA NA
LYS C:82 C:82 148.0 0.74 E -96.2 108.6 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 LYS A:82 1:82 139.0 0.695 E -100.8 107.7 139.0 0.695 0.0 HOH
 2.876
 N
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 LYS A:82 A:82 109.0 0.545 E -99.1 117.7 109.0 0.545 0.0 HOH
 2.513
 CE
 O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:82 A:82 158.0 0.79 E -94.6 105.6 158.0 0.79 0.0 HOH
 2.858
 N
 O
LYS C:82 C:82 139.0 0.695 E -94.6 110.7 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:82 A:82 159.0 0.795 E -93.0 106.3 159.0 0.795 0.0 HOH
 2.861
 N
 O
LYS C:82 C:82 159.0 0.795 E -95.6 111.1 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:82 A:82 155.0 0.775 E -96.9 96.0 155.0 0.775 0.0 HOH
 4.130
 CE
 O
LYS C:82 C:82 141.0 0.705 E -94.7 106.9 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:82 A:82 158.0 0.79 E -92.2 105.0 158.0 0.79 0.0 HOH
 2.884
 N
 O
LYS C:82 C:82 137.0 0.685 E -93.0 109.5 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:82 A:82 147.0 0.735 E -91.6 107.5 147.0 0.735 0.0 HOH
 2.887
 N
 O
LYS C:82 C:82 156.0 0.78 E -93.4 109.9 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:82 A:82 157.0 0.785 E -91.4 108.9 157.0 0.785 0.0 HOH
 2.802
 N
 O
LYS C:82 C:82 157.0 0.785 E -94.4 110.5 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:82 A:82 154.0 0.77 E -91.7 105.3 154.0 0.77 0.0 HOH
 2.789
 N
 O
LYS C:82 C:82 154.0 0.77 E -96.4 106.3 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:82 A:82 147.0 0.735 E -91.5 107.2 147.0 0.735 0.0 HOH
 2.904
 N
 O
LYS C:82 C:82 154.0 0.77 E -91.6 110.2 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:82 A:82 159.0 0.795 E -91.4 106.5 159.0 0.795 0.0 HOH
 2.808
 N
 O
LYS C:82 C:82 156.0 0.78 E -95.7 109.1 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 LYS A:82 A:82 145.0 0.725 E -104.8 114.5 145.0 0.725 0.0 HOH
 4.847
 CD
 O
LYS B:82 B:82 129.0 0.645 E -109.3 106.5 129.0 0.645 0.0 HOH
 6.066
 NZ
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 LYS A:82 A:82 149.0 0.745 E -95.6 100.2 149.0 0.745 0.0
LYS B:82 B:82 120.0 0.6 E -85.9 111.3 120.0 0.6 0.0
LYS C:82 C:82 160.0 0.8 E -92.0 100.2 NA NA NA
LYS D:82 D:82 143.0 0.715 E -106.2 109.3 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 LYS A:82 A:82 166.0 0.83 E -93.7 103.0 166.0 0.83 0.0 HOH
 2.966
 N
 O
LYS C:82 B:82 135.0 0.675 E -96.2 103.4 NA NA NA
LYS E:82 C:82 174.0 0.87 E -89.1 105.3 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 LYS A:82 A:82 157.0 0.785 E -96.0 108.6 157.0 0.785 0.0 HOH
 2.729
 O
 O
LYS B:82 B:82 116.0 0.58 E -95.6 111.1 NA NA NA
LYS C:82 C:82 138.0 0.69 E -77.2 110.3 NA NA NA
LYS D:82 D:82 126.0 0.63 E -100.6 116.1 126.0 0.63 0.0 HOH
 2.872
 NZ
 O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 LYS A:82 A:82 139.0 0.695 E -95.8 101.8 139.0 0.695 0.0 HOH
 3.980
 O
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 LYS A:82 A:82 139.0 0.695 E -97.9 108.4 139.0 0.695 0.0 HOH
 2.348
 H
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:82 A:82 147.0 0.735 E -101.6 117.3 147.0 0.735 0.0 HOH
 2.929
 N
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:82 A:82 143.0 0.715 E -93.6 114.2 143.0 0.715 0.0 HOH
 2.828
 O
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:82 A:82 144.0 0.72 E -92.6 116.0 144.0 0.72 0.0 HOH
 2.783
 O
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:82 A:82 143.0 0.715 E -89.8 117.2 143.0 0.715 0.0 HOH
 7.539
 N
 O
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:82 A:82 139.0 0.695 E -94.5 115.4 139.0 0.695 0.0 HOH
 7.270
 N
 O
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:82 A:82 143.0 0.715 E -95.6 112.9 143.0 0.715 0.0 HOH
 2.871
 N
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 LYS B:67 B:82 128.0 0.64 E -106.3 109.3 128.0 0.64 0.0 HOH
 3.050
 N
 O
LYS D:67 D:82 148.0 0.74 E -105.6 110.8 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 VAL A:67 A:82 82.0 0.529 E -90.1 91.0 82.0 0.529 0.0 HOH
 7.781
 CG2
 O
2jet 2 P07338 89.84 5e-83 X-RAY
 2007-09-18 VAL B:64 B:82 88.0 0.568 E -83.5 104.0 88.0 0.568 0.0 HOH
 5.441
 CG1
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 LYS B:67 B:82 149.0 0.745 E -95.2 109.8 149.0 0.745 0.0 HOH
 5.035
 NZ
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 LYS B:67 B:82 148.0 0.74 E -99.1 104.9 148.0 0.74 0.0 HOH
 3.146
 NZ
 O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 LYS B:67 B:82 130.0 0.65 E -106.5 98.9 130.0 0.65 0.0 HOH
 3.865
 O
 O
LYS F:67 G:82 108.0 0.54 E -97.6 90.4 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 LYS B:67 B:82 151.0 0.755 E -123.1 83.4 151.0 0.755 0.0 HOH
 4.485
 CE
 O
LYS F:67 G:82 150.0 0.75 E -78.6 139.4 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 LYS B:67 F:82 131.0 0.655 E -106.7 112.0 131.0 0.655 0.0 HOH
 2.801
 NZ
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 LYS B:67 B:82 130.0 0.65 E -100.3 113.7 130.0 0.65 0.0 HOH
 3.225
 NZ
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 LYS B:67 B:82 153.0 0.765 E -92.0 103.4 153.0 0.765 0.0 APL
HOH
 3.552
2.884
 CE
O
 F11
O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 LYS B:67 B:82 152.0 0.76 E -97.3 109.5 152.0 0.76 0.0 HOH
 2.934
 N
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 LYS B:67 F:82 150.0 0.75 E -85.7 106.1 150.0 0.75 0.0 HOH
 3.788
 O
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 LYS B:67 F:82 145.0 0.725 E -85.2 104.4 145.0 0.725 0.0 HOH
 3.057
 CD
 O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 LYS B:67 F:82 145.0 0.725 E -98.2 100.1 145.0 0.725 0.0 HOH
 5.848
 CG
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 LYS B:67 F:82 129.0 0.645 E -89.8 92.7 129.0 0.645 0.0 HEX
HOH
 8.784
4.539
 N
CD
 C2
O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 LYS B:67 F:82 145.0 0.725 E -103.1 109.9 145.0 0.725 0.0 HOH
 6.026
 CD
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 LYS B:67 B:82 113.0 0.565 E -99.2 102.6 113.0 0.565 0.0 HOH
 2.897
 O
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 LYS B:67 B:82 164.0 0.82 E -104.1 106.3 164.0 0.82 0.0 HOH
 7.976
 C
 O
LYS F:67 F:82 156.0 0.78 E -82.6 125.1 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 LYS B:67 B:82 122.0 0.61 E -109.4 116.7 122.0 0.61 0.0 HOH
 2.993
 N
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 LYS B:67 B:82 155.0 0.775 E -99.6 105.9 155.0 0.775 0.0 HOH
 6.000
 CD
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 LYS B:67 C:82 130.0 0.65 E -110.6 105.1 130.0 0.65 0.0 HOH
 2.716
 O
 O
LYS E:67 D:82 145.0 0.725 E -104.0 106.3 145.0 0.725 0.0 HOH
 2.751
 O
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 LYS B:67 B:82 154.0 0.77 E -85.9 102.3 154.0 0.77 0.0 HOH
 7.675
 CE
 O
LYS E:67 F:82 151.0 0.755 E -85.9 102.3 151.0 0.755 0.0
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 LYS B:67 F:82 151.0 0.755 E -92.6 115.8 151.0 0.755 0.0 HOH
 3.663
 CE
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 LYS B:67 B:82 113.0 0.565 E -103.5 103.1 113.0 0.565 0.0 SO4
HOH
 2.639
3.765
 NZ
CD
 O1
O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 LYS B:67 B:82 148.0 0.74 E -98.1 108.2 148.0 0.74 0.0 HOH
 4.726
 N
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 LYS B:67 B:82 153.0 0.765 E -94.2 109.7 153.0 0.765 0.0 HOH
 2.816
 N
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 LYS B:67 B:82 158.0 0.79 E -99.0 112.8 158.0 0.79 0.0 HOH
 7.932
 N
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 LYS B:67 B:82 133.0 0.665 E -84.4 99.2 133.0 0.665 0.0 HOH
 2.823
 O
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 LYS B:67 B:82 144.0 0.72 E -82.1 97.8 144.0 0.72 0.0 HOH
 3.073
 O
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 LYS B:67 F:82 148.0 0.74 E -97.1 112.8 148.0 0.74 0.0 HOH
 3.853
 NZ
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 LYS D:67 D:82 142.0 0.71 E -98.7 114.0 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 LYS B:67 B:82 147.0 0.735 E -99.3 107.5 147.0 0.735 0.0 HOH
 3.295
 NZ
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 LYS B:67 B:82 149.0 0.745 E -100.3 108.0 149.0 0.745 0.0 HOH
 7.834
 C
 O
LYS E:67 F:82 140.0 0.7 E -94.5 115.2 140.0 0.7 0.0 HOH
 8.141
 C
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 LYS B:67 F:82 135.0 0.675 E -87.3 110.1 135.0 0.675 0.0 HOH
 2.792
 O
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 LYS B:67 B:82 144.0 0.72 E -94.0 109.8 144.0 0.72 0.0 HOH
 8.303
 N
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 LYS B:67 B:82 153.0 0.765 E -94.4 100.4 153.0 0.765 0.0 HOH
 2.680
 CG
 O
LYS E:67 F:82 127.0 0.635 E -103.4 111.4 127.0 0.635 0.0 HOH
 4.096
 O
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 LYS B:67 F:82 147.0 0.735 E -84.0 93.7 147.0 0.735 0.0 HOH
 2.721
 O
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 129.0 0.645 E -103.2 114.0 129.0 0.645 0.0 HOH
 2.753
 NZ
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 150.0 0.75 E -100.0 108.3 150.0 0.75 0.0 HOH
 2.711
 NZ
 O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 134.0 0.67 E -103.4 112.8 134.0 0.67 0.0 HOH
 2.914
 NZ
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 144.0 0.72 E -101.5 110.9 144.0 0.72 0.0 HOH
 2.896
 O
 O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 132.0 0.66 E -102.5 113.5 132.0 0.66 0.0 HOH
 2.833
 N
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 134.0 0.67 E -102.2 109.5 134.0 0.67 0.0 HOH
 2.920
 N
 O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 136.0 0.68 E -103.1 114.3 136.0 0.68 0.0 HOH
 2.843
 O
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 150.0 0.75 E -99.3 109.4 150.0 0.75 0.0 HOH
 2.914
 N
 O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 133.0 0.665 E -102.9 113.6 133.0 0.665 0.0 HOH
 2.817
 O
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 152.0 0.76 E -99.8 103.3 152.0 0.76 0.0 SO4
HOH
 4.269
1.922
 O
CD
 O4
O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 133.0 0.665 E -103.4 113.4 133.0 0.665 0.0 HOH
 2.882
 N
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 LYS B:67 B:82 151.0 0.755 E -100.8 108.3 151.0 0.755 0.0 SO4
HOH
 4.289
2.752
 O
O
 O4
O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 LYS B:67 B:82 157.0 0.785 E -87.6 109.1 157.0 0.785 0.0 HOH
 6.755
 CE
 O
LYS E:67 F:82 118.0 0.59 E -99.9 114.8 118.0 0.59 0.0 HOH
 4.690
 NZ
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 LYS B:67 B:82 150.0 0.75 E -98.1 108.9 150.0 0.75 0.0 HOH
 2.690
 O
 O
LYS E:67 E:82 145.0 0.725 E -99.6 107.8 NA NA NA
LYS H:67 H:82 153.0 0.765 E -98.2 107.8 NA NA NA
LYS K:67 K:82 147.0 0.735 E -99.1 108.5 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 LYS B:67 F:82 137.0 0.685 E -93.8 88.1 137.0 0.685 0.0 HOH
 4.637
 O
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 LYS B:67 F:82 145.0 0.725 E -102.0 112.7 145.0 0.725 0.0 HOH
 3.378
 N
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 LYS B:67 B:82 134.0 0.67 E -101.2 106.4 134.0 0.67 0.0 HOH
 2.867
 O
 O
LYS F:67 b:82 134.0 0.67 E -99.8 103.5 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 LYS B:67 F:82 147.0 0.735 E -93.6 104.2 147.0 0.735 0.0 HOH
 2.097
 NZ
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 VAL A:100 A:100 90.0 0.581 E -90.3 105.3
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 VAL A:100 A:100 92.0 0.594 E -93.2 105.9