Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75257431 . A C CCDS32490.1:NM_001906.4:c.401cAg>cCg_NP_001897.4:p.134Q>P Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
1993-10-31 GLN A:116 E:116 126.0 0.7 T -62.5 -26.2 126.0 0.7 0.0 HOH
2.692
O
O
1cgi 1 P00766 81.63 3e-148 X-RAY
1993-10-31 GLN A:116 E:116 129.0 0.717 S -77.3 -32.9 129.0 0.717 0.0 HOH
3.177
O
O
1cgj 1 P00766 81.63 3e-148 X-RAY
1993-10-31 GLN A:116 E:116 129.0 0.717 S -76.4 -22.5 129.0 0.717 0.0 HOH
3.727
O
O
1chg 1 P00766 81.63 3e-148 X-RAY
1976-11-22 GLN A:116 A:116 115.0 0.639 T -73.0 -36.6 115.0 0.639 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
2000-05-17 GLN A:116 A:116 125.0 0.694 S -68.5 -50.6 125.0 0.694 0.0 HOH
6.882
C
O
1gcd 1 P00766 81.63 3e-148 X-RAY
1994-06-22 GLN A:116 A:116 120.0 0.667 S -70.1 -35.6 120.0 0.667 0.0 SO4
HOH
2.647
2.595
N
O
O3
O
1gl0 1 P00766 81.63 3e-148 X-RAY
2001-11-28 GLN A:116 E:116 129.0 0.717 S -67.6 -20.6 129.0 0.717 0.0 HOH
2.572
O
O
1gl1 1 P00766 81.63 3e-148 X-RAY
2001-11-28 GLN A:116 A:116 123.0 0.683 S -81.5 -12.4 123.0 0.683 0.0 HOH
2.732
O
O
GLN B:116 B:116 133.0 0.739 S -67.7 -30.0 NA NA NA
GLN C:116 C:116 127.0 0.706 S -67.5 -30.3 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
2001-12-05 GLN A:116 1:116 127.0 0.706 S -67.7 -24.9 127.0 0.706 0.0 HOH
2.741
O
O
1oxg 1 P00766 81.63 3e-148 X-RAY
2004-05-18 GLN A:116 A:116 123.0 0.683 T -52.0 -34.8 123.0 0.683 0.0 SO4
HOH
2.874
2.631
OE1
O
O1
O
1p2m 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLN A:116 A:116 146.0 0.811 S -63.8 -24.1 146.0 0.811 0.0 HOH
2.702
O
O
GLN C:116 C:116 122.0 0.678 T -51.2 -44.2 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLN A:116 A:116 123.0 0.683 T -61.3 -27.8 123.0 0.683 0.0 HOH
2.645
O
O
GLN C:116 C:116 122.0 0.678 T -51.4 -40.8 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLN A:116 A:116 133.0 0.739 T -63.4 -30.6 133.0 0.739 0.0 HOH
2.607
O
O
GLN C:116 C:116 122.0 0.678 T -55.4 -36.9 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLN A:116 A:116 123.0 0.683 T -61.7 -29.7 123.0 0.683 0.0 HOH
2.742
O
O
GLN C:116 C:116 119.0 0.661 T -53.8 -36.8 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLN A:116 A:116 127.0 0.706 S -62.1 -30.3 127.0 0.706 0.0 HOH
2.669
O
O
GLN C:116 C:116 124.0 0.689 T -55.8 -33.7 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLN A:116 A:116 126.0 0.7 S -60.4 -32.4 126.0 0.7 0.0 HOH
2.787
O
O
GLN C:116 C:116 121.0 0.672 T -54.1 -37.6 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLN A:116 A:116 128.0 0.711 T -61.1 -29.3 128.0 0.711 0.0 HOH
2.599
O
O
GLN C:116 C:116 123.0 0.683 T -54.8 -33.9 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLN A:116 A:116 126.0 0.7 T -61.1 -29.6 126.0 0.7 0.0 HOH
2.653
O
O
GLN C:116 C:116 124.0 0.689 T -55.4 -33.2 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLN A:116 A:116 126.0 0.7 T -63.0 -25.6 126.0 0.7 0.0 HOH
2.704
O
O
GLN C:116 C:116 122.0 0.678 T -51.5 -40.7 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
1987-04-16 GLN A:116 A:116 129.0 0.717 S -60.6 -28.4 120.0 0.667 0.05 B:P00766:0.05
HOH
2.672
NE2
O
GLN B:116 B:116 127.0 0.706 S -69.4 -32.6 127.0 0.706 0.0 HOH
2.768
O
O
2y6t 1 P00766 81.63 3e-148 X-RAY
2011-04-20 GLN A:116 A:116 129.0 0.717 S -75.9 -35.3 129.0 0.717 0.0 HOH
8.410
O
O
GLN B:116 B:116 126.0 0.7 S -52.7 -51.1 126.0 0.7 0.0
GLN C:116 C:116 132.0 0.733 S -80.0 -35.2 NA NA NA
GLN D:116 D:116 126.0 0.7 S -60.7 -47.0 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
2012-08-01 GLN A:116 A:116 121.0 0.672 T -56.1 -33.5 121.0 0.672 0.0 HOH
2.853
O
O
GLN C:116 B:116 131.0 0.728 T -55.3 -45.0 NA NA NA
GLN E:116 C:116 120.0 0.667 S -67.1 -35.6 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
2014-07-23 GLN A:116 A:116 128.0 0.711 S -62.5 -38.4 128.0 0.711 0.0 HOH
2.674
OE1
O
GLN B:116 B:116 132.0 0.733 S -56.9 -31.9 NA NA NA
GLN C:116 C:116 128.0 0.711 S -62.8 -42.1 NA NA NA
GLN D:116 D:116 120.0 0.667 S -46.6 -44.6 120.0 0.667 0.0 HOH
2.624
O
O
5j4q 1 P00766 81.63 3e-148 X-RAY
2017-04-12 GLN A:116 A:116 131.0 0.728 S -70.2 -21.5 131.0 0.728 0.0 HOH
2.613
O
O
5j4s 1 P00766 81.63 3e-148 X-RAY
2017-04-12 GLN A:116 A:116 131.0 0.728 S -66.5 -31.2 131.0 0.728 0.0 HOH
2.603
O
O
7kty 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLN A:116 A:116 130.0 0.722 S -62.8 -34.3 130.0 0.722 0.0 HOH
2.837
O
O
7ktz 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLN A:116 A:116 129.0 0.717 S -61.4 -35.5 129.0 0.717 0.0 HOH
2.341
OE1
O
7ku0 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLN A:116 A:116 124.0 0.689 S -58.2 -39.9 124.0 0.689 0.0 HOH
2.746
O
O
7ku1 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLN A:116 A:116 130.0 0.722 S -61.5 -39.9 130.0 0.722 0.0 HOH
2.581
O
O
7ku2 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLN A:116 A:116 128.0 0.711 S -63.5 -34.9 128.0 0.711 0.0 HOH
2.691
O
O
7ku3 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLN A:116 A:116 127.0 0.706 S -59.3 -37.6 127.0 0.706 0.0 HOH
2.763
O
O
1dlk 2 P00766 80.87 2e-137 X-RAY
2000-05-03 GLN B:101 B:116 185.0 1.0 T -73.7 -16.0 135.0 0.75 0.25 A:P00766:0.278
HOH
2.580
O
O
GLN D:101 D:116 184.0 1.0 T -60.2 -41.1 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 GLU A:101 A:116 185.0 0.974 T -62.4 -33.8 185.0 0.974 0.0 HOH
7.874
O
O
2jet 2 P07338 89.84 5e-83 X-RAY
2007-09-18 GLU B:98 B:116 185.0 0.974 S -63.2 -40.1 136.0 0.716 0.258 A:P07338:0.258
HOH
2.704
O
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 GLN B:101 B:116 190.0 1.0 T -66.2 -28.8 138.0 0.767 0.233 A:P00766:0.289
HOH
2.594
O
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 GLN B:101 B:116 185.0 1.0 T -64.5 -29.6 125.0 0.694 0.306 A:P00766:0.333
HOH
2.762
O
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 GLN B:101 B:116 176.0 0.978 T -74.5 -25.8 122.0 0.678 0.3 A:P00766:0.3
HOH
2.733
NE2
O
GLN F:101 G:116 182.0 1.0 S -66.1 -47.8 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 GLN B:101 B:116 185.0 1.0 S -99.9 9.7 127.0 0.706 0.294 A:P00767:0.322
HOH
2.680
O
O
GLN F:101 G:116 185.0 1.0 T -54.6 -39.0 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 GLN B:101 F:116 182.0 1.0 S -55.9 -46.5 127.0 0.706 0.294 A:P00766:0.306
HOH
2.634
O
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 GLN B:101 B:116 186.0 1.0 S -63.4 -30.7 126.0 0.7 0.3 A:P00766:0.333
HOH
2.631
O
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 GLN B:101 B:116 186.0 1.0 S -64.0 -37.5 129.0 0.717 0.283 A:P00766:0.317
HOH
2.576
O
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 GLN B:101 B:116 190.0 1.0 S -64.0 -33.7 130.0 0.722 0.278 A:P00766:0.333
HOH
2.648
O
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 GLN B:101 F:116 184.0 1.0 S -71.1 -18.2 117.0 0.65 0.35 A:P00766:0.372
HOH
2.569
O
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 GLN B:101 F:116 181.0 1.0 S -75.4 -22.1 118.0 0.656 0.344 A:P00766:0.35
HEX
HOH
7.646
2.508
O
O
C1
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 GLN B:101 F:116 187.0 1.0 T -63.7 -27.8 113.0 0.628 0.372 A:P00766:0.411
HOH
2.654
O
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 GLN B:101 F:116 176.0 0.978 S -68.4 -35.5 106.0 0.589 0.389 A:P00766:0.389
HEX
HEX
HOH
7.711
8.612
3.241
O
N
O
C5
C4
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 GLN B:101 F:116 188.0 1.0 S -65.2 -29.3 121.0 0.672 0.328 A:P00766:0.372
HOH
2.548
O
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 GLN B:101 B:116 175.0 0.972 S -74.7 -22.3 121.0 0.672 0.3 A:P00766:0.3
HOH
2.939
CD
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 GLN B:101 B:116 172.0 0.956 S -103.3 -18.2 124.0 0.689 0.267 A:P00766:0.267
HOH
2.654
O
O
GLN F:101 F:116 182.0 1.0 T -55.6 -37.7 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 GLN B:101 B:116 185.0 1.0 S -67.2 -32.7 118.0 0.656 0.344 A:P00766:0.372
HOH
2.526
O
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLN B:101 B:116 189.0 1.0 T -63.1 -33.4 129.0 0.717 0.283 A:P00766:0.333
HOH
2.554
O
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 GLN B:101 C:116 190.0 1.0 T -64.5 -33.0 131.0 0.728 0.272 A:P00766:0.328
HOH
2.728
O
O
GLN E:101 D:116 189.0 1.0 S -65.3 -36.5 127.0 0.706 0.294 D:P00766:0.344
HOH
2.742
O
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 GLN B:101 B:116 191.0 1.0 S -60.9 -32.3 143.0 0.794 0.206 A:P00766:0.267
HOH
2.701
O
O
GLN E:101 F:116 193.0 1.0 S -60.9 -32.3 142.0 0.789 0.211 D:P00766:0.283
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 GLN B:101 F:116 174.0 0.967 S -83.9 -22.6 111.0 0.617 0.35 A:P00766:0.35
HOH
2.605
O
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 GLN B:101 B:116 178.0 0.989 S -59.9 -32.3 117.0 0.65 0.339 A:P00766:0.339
HOH
2.571
O
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 GLN B:101 B:116 194.0 1.0 T -58.5 -32.8 124.0 0.689 0.311 A:P00766:0.389
HOH
2.725
O
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 GLN B:101 B:116 191.0 1.0 T -60.7 -30.1 132.0 0.733 0.267 A:P00766:0.328
HOH
2.693
O
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLN B:101 B:116 189.0 1.0 S -65.9 -33.1 133.0 0.739 0.261 A:P00766:0.311
HOH
2.661
O
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 GLN B:101 B:116 174.0 0.967 S -59.5 -45.9 119.0 0.661 0.306 A:P00766:0.306
HOH
2.804
O
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLN B:101 B:116 185.0 1.0 S -72.9 -15.6 122.0 0.678 0.322 A:P00766:0.35
HOH
3.164
O
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 GLN B:101 F:116 186.0 1.0 S -62.6 -37.4 133.0 0.739 0.261 A:P00766:0.294
HOH
2.482
O
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 GLN D:101 D:116 188.0 1.0 T -44.5 -40.3 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLN B:101 B:116 195.0 1.0 T -63.2 -30.9 136.0 0.756 0.244 A:P00766:0.328
SO4
HOH
3.200
2.633
N
O
O3
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 GLN B:101 B:116 197.0 1.0 S -67.6 -35.4 146.0 0.811 0.189 A:P00766:0.283
HOH
2.645
O
O
GLN E:101 F:116 186.0 1.0 S -58.1 -37.2 133.0 0.739 0.261 D:P00766:0.294
HOH
2.581
O
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLN B:101 F:116 171.0 0.95 S -69.9 -25.6 109.0 0.606 0.344 A:P00766:0.344
HOH
2.863
NE2
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 GLN B:101 B:116 189.0 1.0 T -62.9 -38.1 128.0 0.711 0.289 A:P00766:0.339
HOH
2.725
O
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 GLN B:101 B:116 169.0 0.939 S -75.3 -19.9 123.0 0.683 0.256 A:P00766:0.256
HOH
2.024
O
O
GLN E:101 F:116 183.0 1.0 S -58.4 -33.9 136.0 0.756 0.244 D:P00766:0.261
HOH
2.682
O
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLN B:101 F:116 185.0 1.0 S -70.9 -16.3 124.0 0.689 0.311 A:P00766:0.339
HOH
3.292
O
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 186.0 1.0 T -59.2 -33.0 133.0 0.739 0.261 A:P00766:0.294
HOH
2.743
O
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 190.0 1.0 T -55.2 -38.7 127.0 0.706 0.294 A:P00766:0.35
MLA
HOH
6.631
2.530
N
NE2
O1A
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 188.0 1.0 T -58.2 -33.7 136.0 0.756 0.244 A:P00766:0.289
HOH
2.742
O
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 188.0 1.0 T -57.5 -36.7 135.0 0.75 0.25 A:P00766:0.294
MLI
HOH
6.671
2.757
N
O
O9
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 188.0 1.0 T -59.5 -32.6 135.0 0.75 0.25 A:P00766:0.294
HOH
2.719
O
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 185.0 1.0 T -46.8 -46.2 123.0 0.683 0.317 A:P00766:0.344
HOH
2.792
N
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 189.0 1.0 T -59.1 -32.9 136.0 0.756 0.244 A:P00766:0.294
HOH
2.739
O
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 184.0 1.0 T -48.8 -42.1 122.0 0.678 0.322 A:P00766:0.344
HOH
2.636
OE1
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 190.0 1.0 T -58.4 -32.1 135.0 0.75 0.25 A:P00766:0.306
HOH
2.712
O
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 188.0 1.0 T -59.5 -34.4 129.0 0.717 0.283 A:P00766:0.328
SO4
HOH
8.992
2.745
O
O
O1
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 190.0 1.0 T -60.3 -30.2 138.0 0.767 0.233 A:P00766:0.289
HOH
2.735
O
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 GLN B:101 B:116 188.0 1.0 T -59.4 -34.2 133.0 0.739 0.261 A:P00766:0.306
HOH
2.754
O
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 GLN B:101 B:116 171.0 0.95 S -69.1 -22.5 127.0 0.706 0.244 A:P00766:0.244
HOH
3.098
O
O
GLN E:101 F:116 185.0 1.0 S -55.4 -32.9 141.0 0.783 0.217 D:P00766:0.244
HOH
2.699
O
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 GLN B:101 B:116 189.0 1.0 T -61.2 -23.4 132.0 0.733 0.267 A:P00766:0.317
HOH
2.669
O
O
GLN E:101 E:116 185.0 1.0 T -66.3 -18.3 NA NA NA
GLN H:101 H:116 186.0 1.0 T -65.2 -18.5 NA NA NA
GLN K:101 K:116 187.0 1.0 T -62.2 -23.2 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLN B:101 F:116 184.0 1.0 S -57.3 -31.5 120.0 0.667 0.333 A:P00766:0.356
HOH
2.171
NE2
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 GLN B:101 F:116 193.0 1.0 S -64.5 -23.7 123.0 0.683 0.317 A:P00766:0.389
HOH
3.593
O
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 GLN B:101 B:116 177.0 0.983 S -57.0 -37.7 112.0 0.622 0.361 A:P00766:0.361
HOH
2.697
O
O
GLN F:101 b:116 189.0 1.0 S -54.2 -39.1 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 GLN B:101 F:116 190.0 1.0 S -63.2 -34.0 126.0 0.7 0.3 A:P00766:0.356
SO4
HOH
2.981
2.251
N
NE2
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 GLN A:134 A:134 137.0 0.761 S -67.2 -22.6
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 GLN A:134 A:134 134.0 0.744 S -64.1 -25.8